公开(公告)号：US20240018558A1

公开(公告)日：2024-01-18

申请号：US18037320

申请日：2021-11-19

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Jin CHOI ,  Sunyoung YANG ,  Kwang Woo LEE

IPC: C12P13/14 ,  C12N9/88 ,  C12N15/77

CPC classification number: C12P13/14 ,  C12N9/88 ,  C12N15/77 ,  C12Y401/01032 ,  C12R2001/15

Abstract: The present disclosure relates to a microorganism having enhanced L-glutamine production ability and an L-glutamine production method using the same.

公开(公告)号：US20250011750A1

公开(公告)日：2025-01-09

申请号：US18885239

申请日：2024-09-13

Applicant: CJ CheilJedang Corporation

Inventor： Yeon-Jae JANG ,  Sungjae YANG ,  Kwang Soo SHIN ,  Yee-Seul SO ,  Kwang Woo LEE

IPC: C12N9/88 ,  C12P13/06

Abstract: The present disclosure provides a variant polypeptide having an activity of aspartate 1-dicarboxylase; a microorganism including same; a composition for producing beta-alanine or beta-alanine-derived compounds, the composition comprising the microorganism; and a method for producing beta-alanine or beta-alanine-derived compounds, the method comprising a step for culturing the microorganism.

公开(公告)号：US20240101977A1

公开(公告)日：2024-03-28

申请号：US18266500

申请日：2021-12-03

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Heeyeong KIM ,  Jihyun SHIM ,  Kyungrim KIM ,  Kwang Woo LEE ,  Woosung CHOI

IPC: C12N9/10 ,  C12N1/20 ,  C12N15/77 ,  C12P13/06

CPC classification number: C12N9/1096 ,  C12N1/20 ,  C12N15/77 ,  C12P13/06 ,  C12R2001/15 ,  C12Y206/01042

Abstract: The present application relates to a novel branched-chain amino acid aminotransferase variant that decreases the amount of by-products generated during the production of L-isoleucine, a polynucleotide encoding the variant, and a vector comprising the polynucleotide, a microorganism comprising the variant, polynucleotide or vector, and a method for producing L-isoleucine using the microorganism.

公开(公告)号：US20230046561A1

公开(公告)日：2023-02-16

申请号：US17938508

申请日：2022-10-06

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jaewon JANG ,  Kwang Woo LEE ,  Yong Uk SHIN ,  Imsang LEE

IPC: C12P13/08 ,  C12N1/20 ,  C12N9/10 ,  C12P13/06 ,  C12P13/12

Abstract: The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing an aspartate-derived L-amino acid using the modified polypeptide.

公开(公告)号：US20220396815A1

公开(公告)日：2022-12-15

申请号：US17604896

申请日：2021-03-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Jin CHOI ,  Imsang LEE ,  Heeyeong KIM ,  Byeong Soo KIM ,  Kwang Woo LEE

IPC: C12P13/14 ,  C12N15/77 ,  C12N9/00 ,  C40B40/10

Abstract: The present disclosure relates to a modified polypeptide of glutamine synthetase having enhanced activity and a method of producing L-glutamine using the same. Since production of L-glutamine may be increased by using the novel modified polypeptide without a decrease in a growth rate compared to wild-type strains having glutamine synthetase activity, the modified polypeptide may be widely used for mass production of L-glutamine.

公开(公告)号：US20210017510A1

公开(公告)日：2021-01-21

申请号：US16484315

申请日：2019-04-09

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyungrim KIM ,  Hyo Jeong BYUN ,  Kwang Woo LEE ,  Hyung Joon KIM ,  Yong Uk SHIN

IPC: C12N9/26 ,  C12N1/20 ,  C12P13/04 ,  C12P13/08 ,  C12P13/06

Abstract: The present disclosure relates to a microorganism for producing an L-amino acid with enhanced activity of α-glucosidase and a method for producing an L-amino acid using the same. According to the present disclosure, the microorganism of the genus Corynebacterium producing an L-amino acid has enhanced activity of α-glucosidase, thereby improving L-amino acid production yield. Therefore, the microorganism may be very usefully used for L-amino acid production.

公开(公告)号：US20240167065A1

公开(公告)日：2024-05-23

申请号：US17766389

申请日：2021-07-01

Applicant: CJ CheilJedang Corporation

Inventor： Kwang Soo SHIN ,  Kwang Woo LEE ,  Yee-Seul SO ,  Yeon-Jae JANG ,  Jihyun SHIM

IPC: C12P13/02 ,  C12N9/10 ,  C12N15/77 ,  C12P7/42 ,  C12R1/15

CPC classification number: C12P13/02 ,  C12N9/1014 ,  C12N15/77 ,  C12P7/42 ,  C12R2001/15 ,  C12Y201/02011

Abstract: Provided are: a polypeptide having activity of 3-methyl-2-oxobutanoate hydroxymethyltransferase; a microorganism having increased activity of 3-methyl-2-oxobutanoate hydroxymethyltransferase; a composition for producing pantothenic acid and/or pantoic acid, comprising the polypeptide and/or the microorganism, and a pantothenic acid and/or pantoic acid production method comprising a step for culturing the microorganism.

公开(公告)号：US20230098971A1

公开(公告)日：2023-03-30

申请号：US17440172

申请日：2021-04-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyungrim KIM ,  Imsang LEE ,  Heeyeong KIM ,  Kwang Woo LEE

IPC: C12N9/88 ,  C12N15/77 ,  C12P13/06

Abstract: Provided are a novel L-threonine dehydratase variant and a method of producing L-isoleucine using the same.

公开(公告)号：US20220170059A1

公开(公告)日：2022-06-02

申请号：US17600594

申请日：2020-03-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Yon KWON ,  Mina BAEK ,  Seung-ju SON ,  Kwang Woo LEE

IPC: C12P13/08 ,  C07K14/34 ,  C12N15/77 ,  C12N9/06 ,  C12N9/10 ,  C12N9/18

Abstract: The present application relates to a microorganism having an enhanced L-threonine producing ability and a method for producing L-threonine using the same.

公开(公告)号：US20210355514A1

公开(公告)日：2021-11-18

申请号：US16470030

申请日：2019-02-12

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jaewon JANG ,  Kwang Woo LEE ,  Yong Uk SHIN ,  Imsang LEE

IPC: C12P13/08 ,  C12N1/20 ,  C12N9/10 ,  C12P13/06 ,  C12P13/12

Abstract: The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing an aspartate-derived L-amino acid using the modified polypeptide.