公开(公告)号：US20160304919A1

公开(公告)日：2016-10-20

申请号：US15031706

申请日：2014-10-22

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Jin CHOI ,  So Young KIM ,  Chang Il SEO ,  Yong Uk SHIN ,  Young Lyeol YANG ,  Hye Won UM ,  Hye Min PARK ,  Sung Hoo JHON ,  Byung Hoon JUNG

IPC: C12P13/06 ,  C12N9/10

CPC classification number: C12P13/06 ,  C12N9/1029 ,  C12Y203/01046

Abstract: The present invention relates to a polypeptide having a resistant to feedback inhibition by methionine and an activity of homoserine O-succinyltransferase, a O-succinyl homoserine-producing microorganism expressing the polypeptide, and a method for producing O-succinyl homoserine using the same.

公开(公告)号：US20230072150A1

公开(公告)日：2023-03-09

申请号：US17784775

申请日：2021-02-10

Applicant: CJ CheilJedang Corporation

Inventor： Jaewon JANG ,  Jihyun SHIM ,  Sang Min PARK ,  Hyun Won BAE ,  Hyo Jeong BYUN ,  Yong Uk SHIN ,  Han Hyoung LEE ,  Boram LIM ,  Moo Young JUNG ,  Yunjung CHOI

IPC: C12P13/08 ,  C12N15/70 ,  C12N15/77 ,  C07K14/34 ,  C12P13/10

Abstract: Provided are a microorganism comprising variant LysE, and an L-amino acid producing method using same. The variant LysE may improve L-amino acid excretion and/or production capacity compared to a wild type.

公开(公告)号：US20170137853A1

公开(公告)日：2017-05-18

申请号：US15316475

申请日：2015-06-05

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jee Yeon BAE ,  Hyun Ah KIM ,  Yong Uk SHIN ,  So Young KIM ,  Sang Kyoum KIM ,  Kwang Ho NA ,  Ju Hee SEO ,  Sung Kwang SON ,  Hye Ryun YOO ,  Jin Geun CHOI

IPC: C12P13/06 ,  C12N9/02 ,  C12N9/12 ,  C12N9/10 ,  C12N15/52 ,  C12N9/88

CPC classification number: C12P13/06 ,  C07K14/245 ,  C12N9/0008 ,  C12N9/1029 ,  C12N9/1096 ,  C12N9/1205 ,  C12N9/1217 ,  C12N9/88 ,  C12N15/52 ,  C12P13/02 ,  C12R1/12 ,  C12Y102/01011 ,  C12Y203/01031 ,  C12Y206/01001 ,  C12Y207/01039 ,  C12Y207/02004 ,  C12Y401/01031 ,  C12Y402/01022

Abstract: The present disclosure relates to a microorganism producing O-acetylhomoserine with high efficiency and a method for producing O-acetylhomoserine and L-methionine using the microorganism. The present disclosure provides a microorganism producing O-acetylhomoserine having an enhanced activity of a protein which is predicted to export O-acetylhomoserine, and a method for producing O-acetylhomoserine and L-methionine using the microorganism.

公开(公告)号：US20170101655A1

公开(公告)日：2017-04-13

申请号：US14901532

申请日：2015-06-22

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyun Ah KIM ,  Ju Hee SEO ,  Yong Uk SHIN ,  So Young KIM ,  Sang Kyoum KIM ,  Kwang Ho NA ,  Jee Yeon BAE ,  Sung Kwang SON ,  Hye Ryun YOO ,  Jin Geun CHOI

IPC: C12P13/06

CPC classification number: C12P13/06 ,  C12N9/1029 ,  C12N9/1205 ,  C12N9/88 ,  C12N15/52 ,  C12Y203/01031 ,  C12Y203/03001 ,  C12Y207/01039 ,  C12Y401/01031

Abstract: Disclosed is a microorganism of Escherichia sp. producing O-acetyl homoserine, and a method of producing O-acetyl homoserine in high yield using the microorganism.

公开(公告)号：US20160304920A1

公开(公告)日：2016-10-20

申请号：US15031707

申请日：2014-10-22

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Chang Il SEO ,  So Young KIM ,  Yong Uk SHIN ,  Kwang Ho NA ,  Hye Won UM ,  In Kyung HEO

IPC: C12P13/06 ,  C12N9/10

CPC classification number: C12P13/06 ,  C12N9/1029 ,  C12Y203/01046

Abstract: The present invention relates to a polypeptide which is resistant to feedback inhibition by methionine and has an activity of homoserine O-succinyltransferase, a microorganism for producing O-succinylhomoserine which expresses the polypeptide, and a method for producing O-succinylhomoserine using the same.

Abstract translation: 本发明涉及对甲硫氨酸的反馈抑制有抗性并具有高丝氨酸O-琥珀酰基转移酶活性的多肽，用于产生表达多肽的O-琥珀酰高丝氨酸的微生物，以及使用其制备O-琥珀酰高丝氨酸的方法。

公开(公告)号：US20210355514A1

公开(公告)日：2021-11-18

申请号：US16470030

申请日：2019-02-12

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jaewon JANG ,  Kwang Woo LEE ,  Yong Uk SHIN ,  Imsang LEE

IPC: C12P13/08 ,  C12N1/20 ,  C12N9/10 ,  C12P13/06 ,  C12P13/12

Abstract: The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing an aspartate-derived L-amino acid using the modified polypeptide.

公开(公告)号：US20190338322A1

公开(公告)日：2019-11-07

申请号：US16514777

申请日：2019-07-17

Applicant: CJ Cheiljedang Corporation

Inventor： Jee Yeon BAE ,  Ji Hyun SHIM ,  Hyun Ah KIM ,  Juhee SEO ,  Yong Uk SHIN ,  Jae Hee LEE ,  Sang Kyoum KIM ,  So Young KIM

IPC: C12P13/06 ,  C12P13/12 ,  C07K14/245 ,  C12N15/70

Abstract: The present disclosure relates to a protein having the activity of exporting O-acetylhomoserine and a novel modified protein thereof, a microorganism capable of producing O-acetylhomoserine with enhanced expression of the protein, and a method for producing O-acetylhomoserine using the microorganism.

公开(公告)号：US20180135086A1

公开(公告)日：2018-05-17

申请号：US15579188

申请日：2016-06-03

Applicant: CJ Cheiljedang Corporation

Inventor： Jee Yeon BAE ,  Ji Hyun SHIM ,  Hyun Ah KIM ,  Juhee SEO ,  Yong Uk SHIN ,  Jae Hee LEE ,  Sang Kyoum KIM ,  So Young KIM

IPC: C12P13/06 ,  C12P13/12 ,  C12N15/70 ,  C07K14/245

CPC classification number: C12P13/06 ,  C07K14/245 ,  C12N15/70 ,  C12P13/12

Abstract: The present disclosure relates to a protein having the activity of exporting O-acetylhomoserine and a novel modified protein thereof, a microorganism capable of producing O-acetylhomoserine with enhanced expression of the protein, and a method for producing O-acetylhomoserine using the microorganism.

公开(公告)号：US20170159059A1

公开(公告)日：2017-06-08

申请号：US15323429

申请日：2015-06-30

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jin Sook CHANG ,  Ju Eun KIM ,  So Young KIM ,  Kwang Ho NA ,  Yong Uk SHIN ,  Jae Min LEE ,  Jae Hee LEE ,  In Kyung HEO

IPC: C12N15/70 ,  C12N15/52 ,  C12N9/10 ,  C12P17/12 ,  C12N9/06

CPC classification number: C12N15/70 ,  C12N9/0022 ,  C12N9/1077 ,  C12N9/1085 ,  C12N15/09 ,  C12N15/52 ,  C12P17/10 ,  C12P17/12 ,  C12Y104/03016 ,  C12Y204/02019 ,  C12Y205/01072

Abstract: The present invention relates to a recombinant microorganism producing quinolinic acid, more particularly, a microorganism producing quinolinic acid and having attenuated activity or eliminated activity of a protein having a sequence of SEQ ID NO: 1 and a method of producing quinolinic acid by using the recombinant microorganism.

公开(公告)号：US20160304918A1

公开(公告)日：2016-10-20

申请号：US15031703

申请日：2014-10-22

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Jin CHOI ,  So Young KIM ,  Chang Il SEO ,  Yong Uk SHIN ,  Young Lyeol YANG ,  Hye Won UM ,  Hye Min PARK ,  Sung Hoo JHON ,  Byung Hoon JUNG

IPC: C12P13/06 ,  C12N9/10

CPC classification number: C12P13/06 ,  C12N9/1029 ,  C12Y203/01046 ,  Y02P20/52

Abstract: The present invention relates to a polypeptide having a resistant to feedback inhibition by methionine and an activity of homoserine O-succinyltransferase, a O-succinyl homoserine-producing microorganism expressing the polypeptide, and a method for producing O-succinyl homoserine using the same.

Abstract translation: 本发明涉及具有抗甲硫氨酸反馈抑制和高丝氨酸O-琥珀酰基转移酶的活性的多肽，表达该多肽的产生O-琥珀酰高丝氨酸的微生物的活性，以及​​使用该多肽产生O-琥珀酰高丝氨酸的方法。