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    DETECTING THE DECOMPOSITION OF ENZYMES IN A TEST ELEMENT BY MEANS OF CONTROLLED RELEASE OF A PROTECTED ANALYTE
    1.
    发明申请
    DETECTING THE DECOMPOSITION OF ENZYMES IN A TEST ELEMENT BY MEANS OF CONTROLLED RELEASE OF A PROTECTED ANALYTE 审中-公开
    通过受保护分析仪的控制释放检测测试单元中酶的分解

    公开(公告)号：US20130052674A1

    公开(公告)日：2013-02-28

    申请号：US13524199

    申请日：2012-06-15

    申请人： Carina Horn ,  Dieter Heindl ,  Hans-Peter Haar ,  Nelli Steinke

    发明人： Carina Horn ,  Dieter Heindl ,  Hans-Peter Haar ,  Nelli Steinke

    IPC分类号： C12Q1/32 ,  G01N21/77 ,  C12Q1/54

    CPC分类号： C12Q1/54

    摘要： In one form, a diagnostic element for determining at least one analyte is provided. In a further form, an analytical measuring device includes the diagnostic element. Still, other forms are related to methods for the determination of an analyte, correcting a signal generated by an analyte, and/or checking the detection optics of an analytical measuring device using the diagnostic element. Another form is related to a system for the controlled release of a reagent and the use of such a system as a circuit element. Other aspects include, but are not limited to, unique methods, techniques, products, systems and devices involving diagnostic elements.

    摘要翻译： 在一种形式中，提供了用于确定至少一种分析物的诊断元件。 在另一种形式中，分析测量装置包括诊断元件。 仍然，其它形式涉及用于确定分析物的方法，校正由分析物产生的信号和/或使用诊断元件检查分析测量装置的检测光学元件。 另一种形式涉及用于控制释放试剂的系统以及使用诸如电路元件的系统。 其他方面包括但不限于涉及诊断元件的独特方法，技术，产品，系统和设备。

    METHOD AND DEVICE FOR DETERMINING THE CONCENTRATION OF AN ANALYTE USING FLUORESCENCE MEASUREMENT
    3.
    发明申请
    METHOD AND DEVICE FOR DETERMINING THE CONCENTRATION OF AN ANALYTE USING FLUORESCENCE MEASUREMENT 审中-公开
    使用荧光测量法确定分析仪浓度的方法和装置

    公开(公告)号：US20100227348A1

    公开(公告)日：2010-09-09

    申请号：US12696665

    申请日：2010-01-29

    申请人： Wolfgang Petrich ,  Hans-Peter Haar ,  Joachim Hoenes ,  Carina Horn

    发明人： Wolfgang Petrich ,  Hans-Peter Haar ,  Joachim Hoenes ,  Carina Horn

    IPC分类号： C12Q1/54 ,  C12M1/34

    CPC分类号： C12Q1/32 ,  C12Q1/54

    摘要： A method is presented for determining the concentration of an analyte in a liquid sample using a reagent system. The reaction of the sample with the reagent system results in a change of the quantity of a fluorophore, the quantity of the fluorophore correlating with the concentration of the analyte, a characteristic measurement variable for the quantity of the fluorophore being measured, and the concentration of the analyte being determined using an evaluation algorithm on the basis of the measurement variable. The reagent system is integrated in an analysis system and the fluorescence lifetime of the fluorophore is used in the ascertainment of the concentration of the analyte.

    摘要翻译： 提出了一种使用试剂系统确定液体样品中分析物浓度的方法。 样品与试剂系统的反应导致荧光团量的变化，荧光团的量与分析物的浓度相关，测量的荧光团的量的特征测量变量和浓度 使用基于测量变量的评估算法确定分析物。 试剂系统集成在分析系统中，荧光团的荧光寿命用于确定分析物的浓度。

    Test element for determining a body fluid and measurement method
    4.
    发明授权
    Test element for determining a body fluid and measurement method 失效
    用于确定体液的测试元件和测量方法

    公开(公告)号：US08409868B2

    公开(公告)日：2013-04-02

    申请号：US13224751

    申请日：2011-09-02

    申请人： Hans-Peter Haar ,  Carina Horn

    发明人： Hans-Peter Haar ,  Carina Horn

    IPC分类号： G01N21/77 ,  G01N33/48 ,  G01N33/66

    CPC分类号： G01N33/66 ,  G01N21/6408 ,  G01N21/77 ,  G01N21/78 ,  G01N21/8483 ,  G01N33/525 ,  G01N2021/7786 ,  Y10T436/144444

    摘要： A test element for determining a body fluid is provided. The test element, in particular for determining the blood glucose level, includes a detection region which is charged with a reagent sensitive to the body fluid. A function element is arranged in or adjacent to the detection region for detecting at least one status parameter for the detection region, such that the functional element can be evaluated by means of a status measurement. A method for measuring the test element is also disclosed.

    摘要翻译： 提供了一种用于确定体液的测试元件。 测试元件，特别是用于确定血糖水平的测试元件包括带有对体液敏感的试剂的检测区域。 功能元件布置在检测区域中或与检测区域相邻，用于检测用于检测区域的至少一个状态参数，使得可以通过状态测量来评估功能元件。 还公开了一种用于测量测试元件的方法。

    SIMPLIFIED STORAGE OF INTEGRATED SYSTEMS
    6.
    发明申请
    SIMPLIFIED STORAGE OF INTEGRATED SYSTEMS 有权
    简化的集成系统存储

    公开(公告)号：US20120241335A1

    公开(公告)日：2012-09-27

    申请号：US13400267

    申请日：2012-02-20

    申请人： Carina Horn ,  Christian Freitag ,  Hans-Peter Haar ,  Heino Eikmeier

    发明人： Carina Horn ,  Christian Freitag ,  Hans-Peter Haar ,  Heino Eikmeier

    IPC分类号： B65D79/00

    CPC分类号： G01N27/3272 ,  G01N33/48757 ,  G01N33/48764 ,  G01N33/48778

    摘要： Storage containers for storing at least one diagnostic test element including an enzyme and a stabilized coenzyme are disclosed. In addition, diagnostic products which include diagnostic test elements including an enzyme and a stabilized coenzyme, as well as analytical measuring devices which include such storage containers or diagnostic products, are also disclosed. Other aspects include, but are not limited to, unique methods, techniques, products, systems and devices involving test elements which include an enzyme and a stabilized coenzyme.

    摘要翻译： 公开了用于存储至少一种包括酶和稳定化辅酶的诊断测试元件的储存容器。 此外，还公开了包括酶和稳定化辅酶的诊断测试元件以及包括这种储存容器或诊断产品的分析测量装置的诊断产品。 其他方面包括但不限于独特的方法，技术，产品，系统和涉及包括酶和稳定化辅酶的测试元件的设备。

    TEST ELEMENT FOR DETERMINING A BODY FLUID AND MEASUREMENT METHOD
    7.
    发明申请
    TEST ELEMENT FOR DETERMINING A BODY FLUID AND MEASUREMENT METHOD 失效
    用于确定体液和测量方法的测试单元

    公开(公告)号：US20120045843A1

    公开(公告)日：2012-02-23

    申请号：US13224751

    申请日：2011-09-02

    申请人： Hans-Peter Haar ,  Carina Horn

    发明人： Hans-Peter Haar ,  Carina Horn

    IPC分类号： G01N21/64 ,  G01N21/75 ,  G01N33/66

    CPC分类号： G01N33/66 ,  G01N21/6408 ,  G01N21/77 ,  G01N21/78 ,  G01N21/8483 ,  G01N33/525 ,  G01N2021/7786 ,  Y10T436/144444

    摘要： A test element for determining a body fluid, in particular for determining the blood glucose level, comprises a detection region which is charged with a reagent sensitive to the body fluid. A function element is arranged in and/or adjacent to the detection region for detecting at least one status parameter for the detection region, wherein said functional element can be evaluated by means of a status measurement. A method for measuring the test element is also disclosed.

    摘要翻译： 用于确定体液的测试元件，特别是用于确定血液葡萄糖水平的测试元件包括带有对体液敏感的试剂的检测区域。 功能元件布置在检测区域和/或邻近检测区域中，用于检测用于检测区域的至少一个状态参数，其中可以通过状态测量来评估功能元件。 还公开了一种用于测量测试元件的方法。

    ANALYTICAL SYSTEM FOR DETECTING AN ANALYTE IN A BODY FLUID AND DISPOSABLE INTEGRATED PUNCTURING AND ANALYZING ELEMENT
    8.
    发明申请
    ANALYTICAL SYSTEM FOR DETECTING AN ANALYTE IN A BODY FLUID AND DISPOSABLE INTEGRATED PUNCTURING AND ANALYZING ELEMENT 有权

    公开(公告)号：US20080262386A1

    公开(公告)日：2008-10-23

    申请号：US12105596

    申请日：2008-04-18

    申请人： Hans-Peter Haar ,  Joachim Hoenes ,  Carina Horn ,  Andreas Poredda

    发明人： Hans-Peter Haar ,  Joachim Hoenes ,  Carina Horn ,  Andreas Poredda

    IPC分类号： A61B5/157

    CPC分类号： A61B5/157 ,  A61B5/14546 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/150442 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150717 ,  A61B5/151 ,  A61B5/15105 ,  A61B5/15142 ,  A61B5/15188 ,  A61B2562/0295

    摘要： An analytical system for detecting an analyte in a body fluid comprises a disposable integrated puncturing and analyzing element and a reusable analytical system. The integrated puncturing and analyzing element includes a puncturing element having a tip for generating a puncture wound in a body part and an elongated flat test strip having a top side and a bottom side. The analyzing instrument having a housing has a holder for holding an integrated puncturing and analyzing element, and a coupling unit which is provided such as to couple the puncturing element to a drive by means of which a puncturing movement of the puncturing element is driven, during which it is moved on a path of movement in the puncturing direction during an advancement phase and, after reaching a reversal point of the puncturing movement, is moved opposite to the puncturing direction in a return phase. The puncturing element is arranged to be parallel to the test strip and such as to be mobile with respect to the test strip along the movement path. The integrated puncturing and analyzing element is held in the holder such that, in a sample application position of the test strip, the top side of the test strip is facing upward and, in a puncturing position of the test strip, the tip of the puncturing element is moved beyond an end of the test strip which is its front end in the puncturing direction, in order to generate a puncture wound in a body part. A sample application area for manual application of a drop exiting from the puncture wound of the body part is provided on the top side of the test strip such that, in the sample application position, the drop is applied to the sample application area from directly above. The housing is shaped to allow access to the sample application area of a test strip positioned in the sample application position, and to allow access to the front end of a test strip which is positioned in the puncturing position.

    Microneedle and method for the production thereof
    10.
    发明授权
    Microneedle and method for the production thereof 有权
    微针及其制造方法

    公开(公告)号：US08671543B2

    公开(公告)日：2014-03-18

    申请号：US13311705

    申请日：2011-12-06

    申请人： Hans-Peter Haar

    发明人： Hans-Peter Haar

    IPC分类号： B21D39/02 ,  B23P11/00 ,  B21G1/00 ,  A61B5/00 ,  A61B5/15 ,  A61B5/151

    CPC分类号： A61B5/14514 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150419 ,  A61B5/150427 ,  A61B5/150511 ,  A61B5/685 ,  A61B17/205 ,  A61M2037/0053 ,  B21G1/08 ,  Y10T29/49826

    摘要： In a process for producing a microneedle (12) that can be inserted into body tissue in which a needle tip (20) and a preferably capillary collecting channel (14) having a distal inlet for body fluid formed at the needle tip (20) are formed, it is provided that at least part of a preform (38) prefabricated from a flat material is shaped into a tubular structure (22) so that the collecting channel (14) is at least substantially annularly closed in the cross-section in the area of the tubular structure (22).

    摘要翻译： 在用于制造可插入体针组织中的微针（12）的方法中，其中在针尖（20）处形成有用于体液的远端入口的针尖（20）和优选的毛细收集通道（14） 形成的是，从平坦材料预制的预成型件（38）的至少一部分成形为管状结构（22），使得收集通道（14）在截面中至少基本上环形封闭 管状结构（22）的面积。