公开(公告)号：US20200248197A1

公开(公告)日：2020-08-06

申请号：US16856536

申请日：2020-04-23

Applicant: Dow AgroSciences LLC

Inventor： Sandeep Kumar ,  Marcelo Ariel German ,  Pahao Wang ,  Todd P. Glancy ,  Shreedharan Sriram ,  Carla N. Yerkes ,  Andrew J. Bowling ,  Heather Pence ,  Andrew E. Robinson

IPC: C12N15/82

Abstract: This disclosure concerns the use of endogenous plant RNAi machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in seed tissues of a dicot plant.

公开(公告)号：US09738705B2

公开(公告)日：2017-08-22

申请号：US14693974

申请日：2015-04-23

Applicant: Dow AgroSciences LLC

Inventor： Eric Hongzheng Ma ,  Guomin Shan ,  Todd P. Glancy ,  Sarah E. Canada

IPC: C07K16/12

CPC classification number: C07K16/1278 ,  C07K2317/14 ,  C07K2317/33 ,  G01N2333/325 ,  G01N2430/10

Abstract: Described herein are murine monoclonal antibodies and methods useful for determining and quantitating the presence of Cry1Ca delta endotoxin. The claimed antibodies specifically bind the core toxin region making them suitable for detecting the native full length Cry1Ca toxin as well as the amino core toxin and N-terminal 29 residue truncated forms.

公开(公告)号：US20150309027A1

公开(公告)日：2015-10-29

申请号：US14693974

申请日：2015-04-23

Applicant: Dow AgroSciences LLC

Inventor： Eric Hongzheng Ma ,  Guomin Shan ,  Todd P. Glancy ,  Sarah E. Canada

IPC: G01N33/577 ,  G01N33/68 ,  C07K16/12

CPC classification number: C07K16/1278 ,  C07K2317/14 ,  C07K2317/33 ,  G01N2333/325 ,  G01N2430/10

Abstract: Described herein are murine monoclonal antibodies and methods useful for determining and quantitating the presence of Cry1Ca delta endotoxin. The claimed antibodies specifically bind the core toxin region making them suitable for detecting the native full length Cry1Ca toxin as well as the amino core toxin and N-terminal 29 residue truncated forms.

Abstract translation: 本文描述了鼠单克隆抗体和可用于测定和定量Cry1Caδ内毒素的存在的方法。 所要求的抗体特异性结合核心毒素区域，使其适合于检测天然全长Cry1Ca毒素以及氨基核心毒素和N末端29残基截短形式。

公开(公告)号：US20170051304A1

公开(公告)日：2017-02-23

申请号：US15232876

申请日：2016-08-10

Applicant: Dow AgroSciences LLC

Inventor： Timothy D. Hey ,  Xu Xiaoping ,  Todd P. Glancy ,  Diaa Alabed ,  Sarah E. Worden ,  Nick X. Wang ,  Carla Ausmus ,  Shao-Ching Hung

IPC: C12N15/82 ,  A01N37/44 ,  C07K14/325

CPC classification number: C12N15/8286 ,  A01N63/02 ,  C07K14/325 ,  Y02A40/162

Abstract: Engineered and modified Cry6Aa insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.

Abstract translation: 公开了工程化和修饰的Cry6Aa杀虫毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

公开(公告)号：US10570182B2

公开(公告)日：2020-02-25

申请号：US15541303

申请日：2015-12-16

Applicant: DOW AGROSCIENCES LLC

Inventor： Joel J. Sheets ,  Kenneth Narva ,  Thomas Meade ,  Timothy D. Hey ,  Sek Yee Tan ,  Audrey Jane Etter ,  Todd P. Glancy ,  Janna Mai Armstrong ,  Tristan E. Coram ,  Krishna M. Madduri ,  James E. King ,  Ryan M. Lee ,  Gaofeng Lin ,  Jianquan Li

IPC: C12N15/82 ,  C07K14/325 ,  A01N63/02 ,  A01N37/46

Abstract: The subject invention concerns Bacillus thuringiensis modified Cry1Ca insecticidal toxins and the polynucleotide sequences which encode these toxins. Uses in transgenic plants are described as are methods for protecting crops from insect pest damage.

公开(公告)号：US20180100162A1

公开(公告)日：2018-04-12

申请号：US15705312

申请日：2017-09-15

Applicant: Dow AgroSciences LLC

Inventor： Sandeep Kumar ,  Marcelo Ariel German ,  Pohao Wang ,  Todd P. Glancy ,  Shreedharan Sriram ,  Carla N. Yerkes ,  Andrew J. Bowling ,  Heather Pence ,  Andrew E. Robinson

IPC: C12N15/82

CPC classification number: C12N15/8218 ,  C12N15/8223 ,  C12N15/8234 ,  C12N15/8274

Abstract: This disclosure concerns the use of endogenous plant RNAi machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in seed tissues of a dicot plant.