公开(公告)号：US12065647B2

公开(公告)日：2024-08-20

申请号：US16971893

申请日：2019-02-22

Applicant: DOW AGROSCIENCES LLC ,  QUEENSLAND UNIVERSITY OF TECHNOLOGY

Inventor： Elane Fishilevich ,  Kenneth Narva ,  Xiaozeng Yang ,  Meghan L. Frey ,  Murugesan Rangasamy ,  Wendy Lo ,  Premchand Gandra ,  Peter Michael Waterhouse

IPC: C12N15/113 ,  A01N63/60 ,  C12N15/82

CPC classification number: C12N15/113 ,  A01N63/60 ,  C12N15/8218 ,  C12N15/8286 ,  C12N2310/14 ,  C12N2310/531

Abstract: This disclosure concerns compositions and methods for novel RNA inhibition molecules (e.g., small/short hairpin RNA (shRNA) molecules), polynucleotides encoding such molecules, use of such novel RNA inhibition molecules to inhibit a target gene by suppressing the expression of the mRNA of the target gene, and for application such as the of control insect pests, and transgenic plants that produce, and are protected, by these novel RNA inhibition molecules are described.

公开(公告)号：US10731176B2

公开(公告)日：2020-08-04

申请号：US15541290

申请日：2015-12-16

Applicant: DOW AGROSCIENCES LLC

Inventor： Timothy D. Hey ,  Meghan L. F. Frey ,  Xiaoping Xu ,  Audrey Jane Etter ,  Elizabeth Caldwell ,  Ted Letherer ,  Navin Elango ,  Kenneth Narva

IPC: C12N15/82 ,  A01N37/46 ,  A01N63/10 ,  C07K14/325

Abstract: DIG-305 insecticidal protein toxins, polynucleotides encoding such toxins, and transgenic plants that produce such toxins are disclosed. Also disclosed are methods for using such toxins to control insect pests in plants, especial crop plants. Methods for preparing transgenic plants expressing the protein toxins and methods for detecting the claimed toxins and polynucleotides in transgenic plants are disclosed.

公开(公告)号：US20160058017A1

公开(公告)日：2016-03-03

申请号：US14831301

申请日：2015-08-20

Applicant: Dow AgroSciences LLC

Inventor： Justin M. Lira ,  Holly Jean Butler ,  Timothy D. Hey ,  Doug A. Smith ,  Kenneth Narva ,  Aaron T. Woosley

IPC: A01N63/02 ,  C07K14/325

CPC classification number: A01N63/02 ,  A01N37/46 ,  C07K14/325 ,  C07K2319/55 ,  C12N15/8286

Abstract: DIG-17 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.

Abstract translation: 公开了DIG-17杀虫毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

公开(公告)号：US10570182B2

公开(公告)日：2020-02-25

申请号：US15541303

申请日：2015-12-16

Applicant: DOW AGROSCIENCES LLC

Inventor： Joel J. Sheets ,  Kenneth Narva ,  Thomas Meade ,  Timothy D. Hey ,  Sek Yee Tan ,  Audrey Jane Etter ,  Todd P. Glancy ,  Janna Mai Armstrong ,  Tristan E. Coram ,  Krishna M. Madduri ,  James E. King ,  Ryan M. Lee ,  Gaofeng Lin ,  Jianquan Li

IPC: C12N15/82 ,  C07K14/325 ,  A01N63/02 ,  A01N37/46

Abstract: The subject invention concerns Bacillus thuringiensis modified Cry1Ca insecticidal toxins and the polynucleotide sequences which encode these toxins. Uses in transgenic plants are described as are methods for protecting crops from insect pest damage.

公开(公告)号：US20160122399A1

公开(公告)日：2016-05-05

申请号：US14928106

申请日：2015-10-30

Applicant: DOW AGROSCIENCES LLC

Inventor： Meghan L.F. Frey ,  Justin M. Lira ,  Xiaoping Xu ,  Ignacio Mario Larrinua ,  Kenneth Narva ,  Timothy D Hey

IPC: C07K14/325 ,  A01N37/46 ,  C12N15/82

CPC classification number: C07K14/325 ,  A01N37/46 ,  C12N15/8286 ,  Y02A40/162

Abstract: DIG-303 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.

Abstract translation: 公开了DIG-303杀虫毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

公开(公告)号：US20160060306A1

公开(公告)日：2016-03-03

申请号：US14830997

申请日：2015-08-20

Applicant: DOW AGROSCIENCES LLC

Inventor： Justin M. Lira ,  Holly Jean Butler ,  Doug A. Smith ,  Kenneth Narva ,  Aaron T. Woosley

IPC: C07K14/325 ,  A01N37/18 ,  C12N15/82

CPC classification number: C07K14/325 ,  A01N37/46 ,  A01N63/02 ,  C12N15/8286 ,  Y02A40/162

Abstract: DIG-14 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.

Abstract translation: 公开了DIG-14杀虫毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

公开(公告)号：US20150366211A1

公开(公告)日：2015-12-24

申请号：US14740326

申请日：2015-06-16

Applicant: Dow AgroSciences LLC

Inventor： Janna Mai Armstrong ,  Audrey Jane Etter ,  Meghan L. F. Frey ,  Premchand Gandra ,  Ted Letherer ,  Gaofeng Lin ,  Krishna M. Madduri ,  Haley R. Mowery ,  Kenneth Narva ,  Joel J. Sheets ,  Sek Yee Tan

IPC: A01N47/44 ,  A01H1/02 ,  C07K14/32 ,  C12N15/82

CPC classification number: C07K14/32 ,  A01N37/46 ,  A01N63/02 ,  C07K14/325 ,  C12N15/8286 ,  Y02A40/162

Abstract: DIG-657 vegetative insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed. The invention includes DIG-657 variants, fragments and analogs.

Abstract translation: 公开了DIG-657营养性杀虫毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。 本发明包括DIG-657变体，片段和类似物。

公开(公告)号：US20170058293A1

公开(公告)日：2017-03-02

申请号：US15237918

申请日：2016-08-16

Applicant: Dow AgroSciences LLC

Inventor： Timothy D. Hey ,  Janna Mai Armstrong ,  Ted Letherer ,  Audrey Jane Etter ,  Meghan L. Frey ,  Haley Ellis ,  Kenneth Narva ,  Xiaoping Xu ,  Krishna M. Madduri ,  Sek Yee Tan ,  Premchand Gandra

IPC: C12N15/82 ,  A01N63/02 ,  C07K14/325

Abstract: Insecticidal toxins derived from Bacillus thuringiensis, polynucleotides encoding such toxins, use of such toxins to control plant pests, and transgenic plants that produce, and are protected, by these toxins are described.

Abstract translation: 描述了衍生自苏云金芽孢杆菌的杀虫毒素，编码这种毒素的多核苷酸，使用这些毒素来控制植物害虫，以及由这些毒素产生和保护的转基因植物。

公开(公告)号：US20160237452A1

公开(公告)日：2016-08-18

申请号：US15047456

申请日：2016-02-18

Applicant: Dow AgroSciences LLC

Inventor： Thomas Meade ,  Kenneth Narva ,  Nicholas P. Storer ,  Joel J. Sheets ,  Aaron T. Woosley ,  Stephanie L. Burton

IPC: C12N15/82 ,  A01N63/02

CPC classification number: C12N15/8286 ,  A01N63/02 ,  C07K14/325 ,  Y02A40/162

Abstract: The subject invention includes methods and plants for controlling European corn borer, said plants comprising a Cry1Ab insecticidal protein and a DIG-3 insecticidal protein to delay or prevent development of resistance by the insect.

公开(公告)号：US20140298536A1

公开(公告)日：2014-10-02

申请号：US14105231

申请日：2013-12-13

Applicant: DOW AGROSCIENCES LLC

Inventor： Kenneth Narva ,  Huarong Li ,  Chaoxian Geng ,  Ignacio M. Larrinua ,  Monica B. Olson ,  Navin Elango ,  Matthew J. Henry ,  Aaron T. Woosley ,  Murugesan Rangasamy

IPC: C12N15/113 ,  C12N15/82

CPC classification number: C12N15/113 ,  C12N15/8286 ,  C12N2310/14 ,  Y02A40/162

Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.

Abstract translation: 本公开涉及核酸分子及其用于通过RNA干扰介导的鞘内鳞翅目害虫中目标编码和转录的非编码序列的抑制来控制鞘翅目害虫的方法。 本公开还涉及用于制备表达可用于控制鞘翅目害虫的核酸分子的转基因植物以及由此获得的植物细胞和植物的方法。