公开(公告)号：US20170157054A1

公开(公告)日：2017-06-08

申请号：US15440630

申请日：2017-02-23

Applicant: DSM IP ASSETS B.V.

Inventor： Markus BECK ,  Hansjoerg GRASS ,  Bruno LEUENBERGER ,  Markus NOWOTNY ,  Christian SCHÄFER ,  Karl Manfred VOELKER

IPC: A61K9/20 ,  A61K31/01 ,  A23L33/155 ,  A23K20/179 ,  A23L5/44 ,  A61K31/047 ,  A23K20/174

CPC classification number: A61K9/2081 ,  A23K20/174 ,  A23K20/179 ,  A23L5/44 ,  A23L33/155 ,  A23V2002/00 ,  A61K8/0241 ,  A61K8/31 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2059 ,  A61K31/01 ,  A61K31/047 ,  A61K2800/52 ,  A61K2800/56 ,  A61Q19/00

Abstract: The present invention relates to formulations of a pharmacological effective fat-soluble active ingredient with a high bioavailability of said fat-soluble active ingredient as well as to their manufacture and use as dietary supplement, food, feed, personal care product and/or pharmaceutical. Such formulations are those which when dissolved, dispersed or diluted in/with water have an extinction E 1/1 at a wavelength in the range of from 200 to 800 nm, preferably in the range of from 250 to 600 nm, more preferably in the range of from 250 to 500 nm, more preferably in the range of from 370 to 485 nm, of ≧380, preferably of ≧600, most preferably ≧900. In preferred embodiments of the formulations of the present invention such formulations show an extrusion loss of fat-soluble active ingredient of ≦30% when pressed to tablets.

公开(公告)号：US20210347961A1

公开(公告)日：2021-11-11

申请号：US17382129

申请日：2021-07-21

Applicant: DSM IP Assets B.V.

Inventor： Karl Manfred VOELKER ,  Gabriela BADOLATO-BÖNISCH ,  Thomas LINDEMANN ,  Andrea HITZFELD ,  Stefanie KIRCHEN

IPC: C08K5/103 ,  A23L2/52 ,  A61K9/00 ,  A61K9/48 ,  A61Q19/00 ,  A61K8/49 ,  A61K8/02 ,  A61K8/06 ,  C08L3/00 ,  A61K8/67 ,  A61K8/73 ,  A61K9/14 ,  A23L29/212 ,  A23L29/30 ,  A23L33/15 ,  A23L29/219 ,  A23P10/40 ,  A23L29/10 ,  C08K5/1545 ,  C08L5/16

Abstract: Powderous formulations are disclosed containing vitamin E which can be produced easily and which can be used in many fields of application, but mainly in beverages.

公开(公告)号：US20160073667A1

公开(公告)日：2016-03-17

申请号：US14889049

申请日：2014-05-06

Applicant: DSM IP ASSETS B.V.

Inventor： Karl Manfred VOELKER ,  Gabriela BADOLATO-BÖNISCH ,  Thomas LINDEMANN ,  Andrea HITZFELD ,  Stefanie KIRCHEN

IPC: A23L1/302 ,  A23L1/00 ,  A23L1/0522 ,  A23L2/52 ,  A23L1/09

CPC classification number: C08K5/103 ,  A23L2/52 ,  A23L29/10 ,  A23L29/212 ,  A23L29/219 ,  A23L29/35 ,  A23L33/15 ,  A23P10/40 ,  A23V2002/00 ,  A61K8/022 ,  A61K8/06 ,  A61K8/4973 ,  A61K8/678 ,  A61K8/732 ,  A61K9/0095 ,  A61K9/145 ,  A61K9/4858 ,  A61K2800/21 ,  A61K2800/594 ,  A61K2800/92 ,  A61Q19/00 ,  C08K5/1545 ,  C08L3/00 ,  C08L5/16 ,  A23V2250/00 ,  A23V2250/5114 ,  A23V2250/712

Abstract: The present invention relates a powderous formulation comprising vitamin E, which can be produced easily and which can be used in many fields of application, but mainly in beverages.

Abstract translation: 本发明涉及包含维生素E的粉末制剂，其可以容易地制备并且可以用于许多应用领域，但主要在饮料中。

公开(公告)号：US20170281777A1

公开(公告)日：2017-10-05

申请号：US15625606

申请日：2017-06-16

Applicant: DSM IP ASSETS B.V.

Inventor： Denis HUG ,  Gabriela BADOLATO BOENISCH ,  Karl Manfred VOELKER

IPC: A61K47/26 ,  A23L33/15 ,  A61K31/355 ,  A61K9/00 ,  A23K20/174 ,  A23K20/158 ,  A23L33/10 ,  A23L2/52

CPC classification number: A61K47/26 ,  A23K20/158 ,  A23K20/174 ,  A23L2/52 ,  A23L33/10 ,  A23L33/15 ,  A23V2002/00 ,  A61K9/0095 ,  A61K31/355

Abstract: The present patent application relates to liquid concentrated vitamin E (and/or vitamin E derivatives) compositions. The liquid composition comprises vitamin E (and/or vitamin E derivatives) and at least 40 wt-% of at least one polyoxyethylene sorbitan monofatty acid ester and said liquid composition has an IU value of at least 0.30 IU/mg (based on the total weight of the liquid composition). Furthermore the present invention is related to the use of such compositions in liquid formulations (especially beverages, such as soft drinks), which are transparent (even after pasteurization).