公开(公告)号：US20160244710A1

公开(公告)日：2016-08-25

申请号：US14915796

申请日：2014-10-03

Applicant: EMD MILLIPORE CORPORATION

Inventor： Amy Wood ,  Dave Kraus ,  Anne Hansen ,  Kara Der ,  James McSweeney

IPC: C12M1/06 ,  C12Q3/00 ,  C12M1/00 ,  B01F3/04 ,  B01F7/22

CPC classification number: C12M27/02 ,  B01F3/04269 ,  B01F3/04531 ,  B01F7/22 ,  B01F13/0863 ,  B01F15/0022 ,  B01F15/00344 ,  B01F15/0085 ,  B01F2003/04297 ,  B01F2003/04631 ,  B01F2003/04673 ,  B01F2215/0073 ,  C12M29/06 ,  C12Q3/00

Abstract: An aeration device, and containers or vessels incorporating the same. The aeration device can comprise a plurality of interchangeable aeration elements that can produce gas bubble of different sizes and deliver them to the contents of the container. Also disclosed are containers, such as a disposable or single-use container, optionally having one or more inlets and one or more outlets, an aeration device including a plurality of aeration elements, and a mixer to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container can be a bioreactors and the aeration device controls the dissolved gas concentration content of the bioreactor contents, thereby facilitating proper growth of cell cultures in the bioreactor.

Abstract translation: 曝气装置，以及装有该装置的容器或容器。 曝气装置可以包括多个可互换曝气元件，其可以产生不同尺寸的气泡并将其输送到容器的内容物。 还公开了容器，例如一次性或一次性容器，可选地具有一个或多个入口和一个或多个出口，包括多个通气元件的曝气装置和用于引起混合，分散，均质化和/或 包含或添加到容器中的一种或多种成分的循环。 容器可以是生物反应器，曝气装置控制生物反应器内容物的溶解气体浓度含量，从而促进生物反应器中细胞培养物的适当生长。