Single use slurrying and chromatography systems

    公开(公告)号:US11253796B2

    公开(公告)日:2022-02-22

    申请号:US16589759

    申请日:2019-10-01

    摘要: Methods and systems for chromatography are disclosed that employ a flexible container configured to fit within a support structure and adapted to receive a filtration or absorptive medium. The flexible container can include at least one inlet, at least one outlet, and a separation barrier peripherally sealed within the container to separate the container into a resin containing portion and a drainage portion. The barrier can be configured to exclude the resin material from the drainage portion while allowing fluids to pass therethrough. The disposable chromatography system can further include one or more agitators disposed within the flexible container and adjustably configured to be raised or lowered in the flexible container. When the agitator is in the raised position, the resin packing material can operate in a settled, packed-bed configuration. Alternatively, the agitator in the lowered position permits the chromatography resin packing material to operate in a mixed, slurry configuration.

    Mixer support assembly for use in an integrated cover and mixer apparatus and anaerobic digester system incorporating same

    公开(公告)号:US11008238B2

    公开(公告)日:2021-05-18

    申请号:US15926622

    申请日:2018-03-20

    申请人: Thomas H. Probst

    发明人: Thomas H. Probst

    IPC分类号: B01F7/22 B01F15/00 C02F3/28

    摘要: A mixer support assembly for use in an integrated cover and mixer apparatus and anaerobic digester system incorporating same provided. The digester system includes a tank with an integrated cover and mixer apparatus which provides a completely or substantially gas tight enclosure for the collection of biogas. The integrated cover and mixer apparatus includes a cover, a mixer, and a mixer support assembly for supporting the mixer. The mixer support assembly includes a float ring and a support body that is selectively removable from the float ring. The support body is attached to the float ring by way of a clamping arrangement.

    OLIGOMERISER WITH IMPROVED MIXING PERFORMANCE

    公开(公告)号:US20200148819A1

    公开(公告)日:2020-05-14

    申请号:US16625887

    申请日:2018-06-29

    摘要: In an embodiment, a reactor for carrying out a melt transesterification reaction at a reactor temperature of 160 to 300° C. and a reactor pressure of 5 to 200 mbar, comprises a cylindrical tank comprising a top, a side, and a bottom, wherein the bottom is convex, extending away from the top; a stirring shaft disposed within the cylindrical tank along an axis thereof so that it is rotatable from outside of the cylindrical tank; an impeller extending from the stirring shaft in the cylindrical tank and comprising a plurality of blades; a reactant solution inlet; a reaction solution outlet; and an externally located heat exchanger in fluid communication with the cylindrical tank via a recirculation stream and a heated stream. The reactor can be used for the polymerization of a polycarbonate oligomer.