公开(公告)号：US09585618B2

公开(公告)日：2017-03-07

申请号：US14237084

申请日：2013-09-16

Applicant: Empire Technology Development LLC

Inventor： Boris Leschinsky ,  Jonathan R. Williams

IPC: A61B5/0492 ,  A61B5/00 ,  A61N1/05 ,  A61N1/08 ,  A61N1/36 ,  A61B5/0488

CPC classification number: A61B5/4893 ,  A61B5/04886 ,  A61B5/0492 ,  A61B5/6848 ,  A61B5/706 ,  A61B2562/043 ,  A61N1/0502 ,  A61N1/0551 ,  A61N1/08 ,  A61N1/36017 ,  A61N1/36057

Abstract: Technologies are generally provided for identifying and marking the location of the laryngeal nerve prior to tissue dissection. A frame may include two multi-electrode stimulating probes, a slider with a guide movable between the two probes, and a marker probe including an anchor. The two probes supported on the frame may be inserted into tissue in a vicinity of the nerve, and a controller may sequentially stimulate the electrodes on each probe and measure electromyography (EMG) responses from each stimulated electrode. The controller may determine the nerve's location relative to the probes based on the measured EMG responses, where the location may include a lateral position between the probes and an estimated depth. The slider may be moved to the lateral position and the marker probe may be inserted through the slider to the determined depth. The anchor may be deployed next to the nerve to indicate the nerve location.

Abstract translation: 通常提供技术用于在组织剥离之前识别和标记喉神经的位置。 框架可以包括两个多电极刺激探针，具有可在两个探针之间移动的引导件的滑块和包括锚固件的标记探针。 支撑在框架上的两个探针可以插入神经附近的组织中，并且控制器可以顺序地刺激每个探针上的电极并测量来自每个受激电极的肌电图（EMG）响应。 控制器可以基于测量的EMG响应来确定相对于探针的神经位置，其中位置可以包括探针之间的横向位置和估计的深度。 滑动器可以移动到横向位置，并且标记探针可以通过滑块插入到确定的深度。 锚可以部署在神经旁边以指示神经位置。

公开(公告)号：US09204807B2

公开(公告)日：2015-12-08

申请号：US14006801

申请日：2013-02-15

Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLC

Inventor： Boris Leschinsky ,  Jonathan Williams ,  Robert B. Schock

IPC: A61B5/00 ,  A61B5/01

CPC classification number: A61B5/015 ,  A61B5/0075

Abstract: Systems and methods for remote thermographic assessment of tissue viability are disclosed. A system may include a controllable source of one or more thermal stimuli to be applied to a tissue, a measurement system to measure a heat response of the tissue before, during, and/or after the application of the thermal stimuli, and an electronic device that may control either one or both of the source of thermal stimuli and the measurement system. The electronic device may also receive tissue thermal response data from the measurement system, and may further calculate a measure of tissue viability. A method of determining tissue viability may include supplying a thermal stimulus to a tissue, receiving, by a measurement device, the thermal response of the tissue to the stimuli, and a comparison of the thermal response data to at least some viability threshold values. The results may be displayed in a graphical manner.

Abstract translation: 公开了远程热成像评估组织存活力的系统和方法。 系统可以包括要施加到组织的一个或多个热刺激的可控源，测量系统以在施加热刺激之前，期间和/或之后测量组织的热响应，以及电子设备 这可以控制热刺激源中的一个或两个和测量系统。 电子设备还可以从测量系统接收组织热响应数据，并且还可以计算组织存活力的量度。 确定组织活力的方法可以包括向组织提供热刺激，通过测量装置接收组织对刺激的热响应，以及热响应数据与至少一些活力阈值的比较。 结果可以以图形方式显示。

公开(公告)号：US20150223720A1

公开(公告)日：2015-08-13

申请号：US14237084

申请日：2013-09-16

Applicant: EMPIRE TECHNOLOGY DEVELOPMENT, LLC

Inventor： Boris Leschinsky ,  Jonathan R. Williams

IPC: A61B5/0492 ,  A61B5/00 ,  A61B5/0488

CPC classification number: A61B5/4893 ,  A61B5/04886 ,  A61B5/0492 ,  A61B5/6848 ,  A61B5/706 ,  A61B2562/043 ,  A61N1/0502 ,  A61N1/0551 ,  A61N1/08 ,  A61N1/36017 ,  A61N1/36057

Abstract: Technologies are generally provided for identifying and marking the location of the laryngeal nerve prior to tissue dissection. A frame may include two multi-electrode stimulating probes, a slider with a guide movable between the two probes, and a marker probe including an anchor. The two probes supported on the frame may be inserted into tissue in a vicinity of the nerve, and a controller may sequentially stimulate the electrodes on each probe and measure electromyography (EMG) responses from each stimulated electrode. The controller may determine the nerve's location relative to the probes based on the measured EMG responses, where the location may include a lateral position between the probes and an estimated depth. The slider may be moved to the lateral position and the marker probe may be inserted through the slider to the determined depth. The anchor may be deployed next to the nerve to indicate the nerve location.

Abstract translation: 通常提供技术用于在组织剥离之前识别和标记喉神经的位置。 框架可以包括两个多电极刺激探针，具有可在两个探针之间移动的引导件的滑块和包括锚固件的标记探针。 支撑在框架上的两个探针可以插入神经附近的组织中，并且控制器可以顺序地刺激每个探针上的电极并测量来自每个受激电极的肌电图（EMG）响应。 控制器可以基于测量的EMG响应来确定相对于探针的神经位置，其中位置可以包括探针之间的横向位置和估计的深度。 滑动器可以移动到横向位置，并且标记探针可以通过滑块插入到确定的深度。 锚可以部署在神经旁边以指示神经位置。

公开(公告)号：US20150105810A1

公开(公告)日：2015-04-16

申请号：US14356391

申请日：2013-09-16

Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLC

Inventor： Boris Leschinsky ,  Jonathan R. Williams

IPC: A61B17/32 ,  A61B17/11 ,  A61B19/00

CPC classification number: A61B17/32002 ,  A61B5/0261 ,  A61B17/1114 ,  A61B17/320016 ,  A61B2017/00057 ,  A61B2017/00061 ,  A61B2017/00066 ,  A61B2090/0811 ,  A61B2562/046

Abstract: Technologies are provided for an opto-mechancial device is provided for enabling surgeons to rapidly simulate proposed intestinal/colorectal anastomosis cut lines and assess their impact upon tissue perfusion prior to their implementation. The pre-selection process enables a surgeon to decide upon the locations of the anastomotic cut lines that are most likely to reduce ischemia, while preserving most of the intestinal tissue length. The opto-mechanical device may simulate a cut line by applying pressure to intestinal tissue and detecting a light pattern transmitted through the intestinal tissue before and after the applied pressure. A perfusion map may be generated to estimate perfusion quality around the circumference of the intestinal tissue at the site of a simulated cut line, and the perfusion map may be displayed as a two-dimensional graphic image of the proposed anastomosis site. Once the site of the best cut line is selected, the surgeon may activate a cutting blade to implement the cut.

Abstract translation: 提供了一种用于光学机械装置的技术，用于使外科医生能够快速模拟所提出的肠/结肠直肠吻合切割线并评估其在组织灌注之前对其实施的影响。 预选过程使得外科医生能够决定最有可能减少缺血的吻合切割线的位置，同时保留大部分肠组织长度。 光学机械装置可以通过对肠组织施加压力并且在施加的压力之前和之后检测透过肠组织的光图案来模拟切割线。 可以产生灌注图，以估计在模拟切割线的部位的肠组织周围的灌注质量，并且灌注图可以显示为所提出的吻合部位的二维图形图像。 一旦选择了最佳切割线的部位，外科医生可以激活切割刀片来实现切割。

公开(公告)号：US20140236020A1

公开(公告)日：2014-08-21

申请号：US14006801

申请日：2013-02-15

Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLC

Inventor： Boris Leschinsky ,  Jonathan Williams ,  Robert B. Schock

IPC: A61B5/00 ,  A61B5/01

CPC classification number: A61B5/015 ,  A61B5/0075

Abstract: Systems and methods for remote thermographic assessment of tissue viability are disclosed. A system may include a controllable source of one or more thermal stimuli to be applied to a tissue, a measurement system to measure a heat response of the tissue before, during, and/or after the application of the thermal stimuli, and an electronic device that may control either one or both of the source of thermal stimuli and the measurement system. The electronic device may also receive tissue thermal response data from the measurement system, and may further calculate a measure of tissue viability. A method of determining tissue viability may include supplying a thermal stimulus to a tissue, receiving, by a measurement device, the thermal response of the tissue to the stimuli, and a comparison of the thermal response data to at least some viability threshold values. The results may be displayed in a graphical manner.

Abstract translation: 公开了远程热成像评估组织存活力的系统和方法。 系统可以包括要施加到组织的一个或多个热刺激的可控源，测量系统以在施加热刺激之前，期间和/或之后测量组织的热响应，以及电子设备 这可以控制热刺激源中的一个或两个和测量系统。 电子设备还可以从测量系统接收组织热响应数据，并且还可以计算组织存活力的量度。 确定组织活力的方法可以包括向组织提供热刺激，通过测量装置接收组织对刺激的热响应，以及热响应数据与至少一些活力阈值的比较。 结果可以以图形方式显示。

公开(公告)号：US09713480B2

公开(公告)日：2017-07-25

申请号：US14356391

申请日：2013-09-16

Applicant: Empire Technology Development LLC

Inventor： Boris Leschinsky ,  Jonathan R. Williams

IPC: A61B5/026 ,  A61B17/32 ,  A61B17/11 ,  A61B17/00 ,  A61B90/00

CPC classification number: A61B17/32002 ,  A61B5/0261 ,  A61B17/1114 ,  A61B17/320016 ,  A61B2017/00057 ,  A61B2017/00061 ,  A61B2017/00066 ,  A61B2090/0811 ,  A61B2562/046

Abstract: Technologies are provided for an opto-mechanical device for enabling surgeons to rapidly simulate proposed intestinal/colorectal anastomosis cut lines and assess their impact upon tissue perfusion prior to their implementation. The pre-selection process enables a surgeon to decide upon the locations of the anastomotic cut lines that are most likely to reduce ischemia, while preserving most of the intestinal tissue length. The opto-mechanical device may simulate a cut line by applying pressure to intestinal tissue and detecting a light pattern transmitted through the intestinal tissue before and after the applied pressure. A perfusion map may be generated to estimate perfusion quality around the circumference of the intestinal tissue at the site of a simulated cut line, and the perfusion map may be displayed as a two-dimensional graphic image of the proposed anastomosis site. Once the site of the best cut line is selected, the surgeon may activate a cutting blade to implement the cut.