公开(公告)号：US20210356474A1

公开(公告)日：2021-11-18

申请号：US17390010

申请日：2021-07-30

Applicant: FUJIFILM Corporation

Inventor： Kazuhiro NAKAMURA ,  Ryo OUCHI ,  Takeru SHIGEMURA

IPC: G01N33/68 ,  G01N33/543 ,  G01N21/64

Abstract: An object of the present invention is to provide a reagent kit, a measurement kit, and a measurement method for measuring serum amyloid A, which enable simple and rapid measurement of serum amyloid A by promoting dissociation of the serum amyloid A from HDL and carrying out an antigen-antibody reaction. According to the present invention, provided is a reagent kit for measuring serum amyloid A, including first particles having a label and modified with a first binding substance having a property of specifically binding to serum amyloid A, at least one nonionic surfactant having an HLB value of 17 to 20, which is defined by (inorganicity value/organicity value)×10, and a molecular weight of 1000 or less, and a buffer capable of adjusting a pH of a reaction solution to be in a range of 5.5 to 7.0 or a range of 8.5 to 9.0.

公开(公告)号：US20210356458A1

公开(公告)日：2021-11-18

申请号：US17389675

申请日：2021-07-30

Applicant: FUJIFILM Corporation

Inventor： Kazuhiro NAKAMURA ,  Ryo OUCHI ,  Takeru SHIGEMURA

IPC: G01N33/545 ,  C07K16/18

Abstract: An object of the present invention is to provide a reagent kit, a measurement kit, and a measurement method for immunologically measuring SAA with high accuracy and high sensitivity without using an alcohol designated as a hazardous material on the fire protection law. According to the present invention, provided is a reagent kit for measuring serum amyloid A, including first particles having a label and modified with a first binding substance having a property of specifically binding to serum amyloid A, at least one nonionic surfactant having a molecular weight of 1000 or less, and a buffer adjusting a pH of a reaction solution to be in a range of 5.5 to 7.0 or a range of 8.5 to 9.0.

公开(公告)号：US20250102512A1

公开(公告)日：2025-03-27

申请号：US18975901

申请日：2024-12-10

Applicant: FUJIFILM Corporation

Inventor： Ryo OUCHI ,  Kazuhiro NAKAMURA

IPC: G01N33/68 ,  G01N33/543

Abstract: An object of the present invention is to provide a reagent kit, a measurement kit, and a measurement method for immunologically measuring serum amyloid A with high accuracy and high sensitivity without using an alcohol designated as a hazardous material on the fire protection law. According to the present invention, provided is a reagent kit for measuring serum amyloid A, including first particles having a label and modified with a first binding substance having a property of specifically binding to serum amyloid A, and at least one nonionic surfactant having a molecular weight of 1000 or less.

公开(公告)号：US20150355175A1

公开(公告)日：2015-12-10

申请号：US14730378

申请日：2015-06-04

Applicant: FUJIFILM Corporation

Inventor： Nobuhiko FUJIWARA ,  Noriyuki KASAGI ,  Toshihito KIMURA ,  Kazuhiro NAKAMURA

IPC: G01N33/543

CPC classification number: G01N33/54386 ,  G01N21/553 ,  G01N21/64 ,  G01N21/648 ,  G01N21/82 ,  G01N33/54373 ,  G01N33/553 ,  G01N2021/825

Abstract: To provide a test substance measurement method and a test substance measurement kit adapted to improve the accuracy of the measurement of a test substance. A test substance measurement kit includes: fluorescent particles which are modified with a first binding substance having specific bindability to a test substance; non-fluorescent particles which are modified with a second binding substance having no specific bindability to the test substance; and a substrate on which a first metal film to which a third binding substance having specific bindability to the test substance is fixed, and a second metal film to which a fourth binding substance having no bindability to the test substance, but having bindability to the first binding substance is fixed, and which has a smaller thickness than the first metal film are formed.

Abstract translation: 提供测试物质测量方法和用于提高测试物质测量精度的测试物质测量套件。 测试物质测量试剂盒包括：用与测试物质具有特异性结合性的第一结合物修饰的荧光颗粒; 用对被检物质没有特异性结合性的第二结合物修饰的非荧光粒子; 和固定具有与测试物质具有特异性结合力的第三结合物质的第一金属膜的基材，以及第二金属膜，对测试物质不具有粘合性但与第一粘合物具有粘合性的第四结合物质 固定物质，并且形成比第一金属膜小的厚度。

公开(公告)号：US20160069909A1

公开(公告)日：2016-03-10

申请号：US14840710

申请日：2015-08-31

Applicant: FUJIFILM Corporation

Inventor： Kazuhiro NAKAMURA ,  Noriyuki KASAGI ,  Hiroyuki CHIKU ,  Kentaro NAKAMURA

IPC: G01N33/74 ,  G01N33/58 ,  G01N33/553

CPC classification number: G01N33/74 ,  G01N33/54313 ,  G01N33/54346 ,  G01N33/553 ,  G01N33/582 ,  G01N33/587 ,  G01N2333/695

Abstract: The present invention provides a reagent kit which is used for measuring a test substance in a biological sample and can improve measurement sensitivity of the test substance; measurement kit; and a method of measuring the test substance. Provided is a reagent kit which is used for measuring the above-described test substance in the biological sample and contains first particles which are modified by a first binding substance having specific binding properties with respect to the test substance and have a label, and a compound which has at least one amino group having a positive charge.

Abstract translation: 本发明提供了一种用于测量生物样品中测试物质并可提高测试物质的测量灵敏度的试剂盒; 测量套件; 以及测定被检物质的方法。 提供一种试剂盒，其用于测量生物样品中的上述测试物质，并含有由相对于被检物质具有特异性结合特性的第一结合物修饰并具有标记的第一颗粒和化合物 其具有至少一个具有正电荷的氨基。

公开(公告)号：US20130323192A1

公开(公告)日：2013-12-05

申请号：US13958941

申请日：2013-08-05

Applicant: FUJIFILM Corporation

Inventor： Kazuhiro NAKAMURA

IPC: A61K8/46 ,  A61Q1/02

CPC classification number: A61K8/466 ,  A61K8/0216 ,  A61K8/0241 ,  A61K2800/56 ,  A61Q1/02

Abstract: Provided are a method of producing a base makeup cosmetic, which includes mixing a solvent and a cosmetic base material including a red composite powder having a composite structure in which red pigment selected from the group consisting of lithol rubine B and lithol rubine BCA is intercalated into an inorganic substance, and filling the slurry into a container and then removing the solvent, as well as a base makeup cosmetic.

Abstract translation: 本发明提供一种基础化妆品的制造方法，其特征在于，包括混合溶剂和化妆品基材，所述化妆品基材含有具有复合结构的红色复合粉末，其中选自由伊蔻红宝石B和石脑油红宝石BCA组成的组的红色颜料插入 无机物质，并将浆料填充到容器中，然后除去溶剂，以及基础化妆品。