-
1.
公开(公告)号:US06984726B1
公开(公告)日:2006-01-10
申请号:US09647234
申请日:1999-03-25
申请人: Fatima Ferreira , Klaus Richter , Martin Himly , Edwin Engel , Christof Ebner , Michael Breitenbach , Dietrich Kraft
发明人: Fatima Ferreira , Klaus Richter , Martin Himly , Edwin Engel , Christof Ebner , Michael Breitenbach , Dietrich Kraft
IPC分类号: C07H21/04
CPC分类号: C07K14/415 , A61K39/00
摘要: The invention relates to DNA molecules which code for the allergen Art v 1 or isoforms thereof, the sequence of the allergen, a method for the production of an Art v 1 molecule, a vector and a transformed host cell.
摘要翻译: 本发明涉及编码变应原Art v 1或其同工型的DNA分子,变应原的序列,Art v 1分子的生产方法,载体和转化的宿主细胞。
-
公开(公告)号:US20110217334A1
公开(公告)日:2011-09-08
申请号:US12674195
申请日:2008-06-30
申请人: Michael Wallner , Barbara Bohle , Martin Himly , Nicole Wopfner , Gabriele Gadermaier , Matthias Egger , Peter Lackner , Fatima Ferreira , Michael Hauser
发明人: Michael Wallner , Barbara Bohle , Martin Himly , Nicole Wopfner , Gabriele Gadermaier , Matthias Egger , Peter Lackner , Fatima Ferreira , Michael Hauser
IPC分类号: A61K39/35 , C07K14/415 , C12N15/63 , C07H21/00 , A61P37/08
CPC分类号: C07K14/415
摘要: The present invention relates to a hypoallergenic molecule consisting of Bet v Ia or an allergen having at least 40% identity to Bet v Ia comprising mutations of at least four amino acid residues in the region of amino acids 100 to 125 of Bet v Ia or its corresponding region of the allergen having at least 40% identity to Bet v Ia.
摘要翻译: 本发明涉及由Bet v 1a或与Bet v Ia具有至少40%同一性的变应原组成的低变应原性分子,其包含Bet v Ia的氨基酸100至125的区域中至少四个氨基酸残基的突变或其 与Bet v Ia具有至少40%同一性的变应原的相应区域。
-
公开(公告)号:US09040054B2
公开(公告)日:2015-05-26
申请号:US12674195
申请日:2008-06-30
申请人: Michael Wallner , Barbara Bohle , Martin Himly , Nicole Wopfner , Gabriele Gadermaier , Matthias Egger , Peter Lackner , Fatima Ferreira , Michael Hauser
发明人: Michael Wallner , Barbara Bohle , Martin Himly , Nicole Wopfner , Gabriele Gadermaier , Matthias Egger , Peter Lackner , Fatima Ferreira , Michael Hauser
IPC分类号: A61K36/00 , A61K39/00 , A61K39/35 , A61K39/36 , C07K1/00 , C07K14/00 , C07K16/00 , C07K17/00 , C07K14/415
CPC分类号: C07K14/415
摘要: The present invention relates to a hypoallergenic molecule consisting of Bet v Ia or an allergen having at least 40% identity to Bet v Ia comprising mutations of at least four amino acid residues in the region of amino acids 100 to 125 of Bet v Ia or its corresponding region of the allergen having at least 40% identity to Bet v 1a.
摘要翻译: 本发明涉及由Bet v 1a或与Bet v Ia具有至少40%同一性的变应原组成的低变应原性分子,其包含Bet v Ia的氨基酸100至125的区域中至少四个氨基酸残基的突变或其 与Bet v 1a具有至少40%同一性的变应原的相应区域。
-
公开(公告)号:US20140242668A1
公开(公告)日:2014-08-28
申请号:US14131593
申请日:2012-07-09
IPC分类号: C12N9/88
CPC分类号: C12N9/88 , C12Y402/02
摘要: The present invention relates to a variant of a mature polysaccharide lyase having a beta helix structure, wherein said variant comprises an N- and/or C-terminal truncation and consists essentially of at least 90% of the beta helix structure of the mature polysaccharide lyase.
摘要翻译: 本发明涉及具有β螺旋结构的成熟多糖裂解酶的变体,其中所述变体包含N-和/或C-末端截短并且基本上由至少90%的成熟多糖裂解酶的β螺旋结构组成 。
-
-
-