摘要:
The invention relates to DNA molecules which code for the allergen Art v 1 or isoforms thereof, the sequence of the allergen, a method for the production of an Art v 1 molecule, a vector and a transformed host cell.
摘要翻译:本发明涉及编码变应原Art v 1或其同工型的DNA分子,变应原的序列,Art v 1分子的生产方法,载体和转化的宿主细胞。
摘要:
The invention relates to polypeptides made of mannitol-dehydrogenase of Cladosporium herbarum and Alternaria alternata nucleic acids coding therefor and the use thereof in diagnosis and therapy.
摘要:
The invention relates to polypeptides made of mannitol-dehydrogenase of Cladosporium herbarum and Alternaria alternata nucleic acids coding therefor and the use thereof in diagnosis and therapy.
摘要:
The invention provides recombinant DNA molecules which code for polypeptides that exhibit the antigenicity of a P14 allergen of birch Betula verrucosa and other plants of the order Fagales, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. A method is provided that permits purification of P14 allergens or cross reactive allergens by means of binding to poly(L-proline). In addition, methods are described for making the proteins and polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of diseases.
摘要:
This invention provides recombinant DNA molecules which code for polypeptides that exhibit the antigenicity of an Aln g I allergen of alder, Alnus sp., of a Cor a I allergen of hazel or of a Bet v I allergen of birch and other plants of the order Fageles, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. In addition, methods are described for using the polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of allergic diseases.
摘要翻译:PCT No.PCT / EP91 / 01479 371日期:1992年6月1日 102(e)日期1992年6月1日PCT 1991年8月6日PCT PCT。 出版物WO92 / 02621 日本1992年2月20日本发明提供重组DNA分子,其编码多肽,其表现出榛子al an an a a a a haz haz haz haz of of of of and and and and and and and and and and and and and and and and and and and and and 对于包含其至少一个表位的多肽,以及在严格条件下与这些DNA序列杂交或通过遗传密码的简并性可从这些序列衍生的核酸,其它植物的Fageles序列。 此外,描述了使用由这些DNA分子编码的多肽及其在过敏性疾病的诊断或治疗中的用途的方法。
摘要:
The invention relates to a method by which expression cDNA clone banks are screened by means of IgE antibodies derived from the sera of allergic individuals, or by means of monoclonal or polyconal antibodies. This type of screening is used for the detection of polynucleotides whose open-reading frames code for allergenically active proteins. These proteins are characterized in that their biological activity as allergens is equal to that of plant allergens occurring in nature.
摘要:
The invention provides recombinant DNA molecules which code for proteins or polypeptides that exhibit the antigenicity of a P14 allergen of birch Betula verrucosa and other plants of the order Fagales, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. A method is provided that permits purification of P14 allergens or cross-reactive allergens by means of binding to poly(L-proline). In addition, methods are described for making the proteins and polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of allergic diseases.
摘要:
The invention relates to a method by which expression cDNA clone banks are screened by means of IgE antibodies derived from the sera of allergic individuals, or by means of monoclonal or polyclonal antibodies. This type of screening is used for the detection of polynucleotides whose open-reading frames code for allergenically active proteins. These proteins are characterized in that their biological activity as allergens is equal to that of plant allergens occurring in nature.
摘要:
Recombinant materials, including DNA constructs, expression vectors, and host cells, and methods of identifying an environmental stimulus or a gene that alters the lifespan of an organism are identified. The recombinant DNA constructs include first and second chimeric genes that both encode substantially the same protein that is required for yeast replication, the first chimeric gene containing a promoter responsive to growth medium conditions and the second chimeric gene containing a promoter operable in mother cells but not daughter cells.
摘要:
In at least one aspect of the invention, systems are provided that comprise at least one computing device coupled to a plurality of other computing devices that are operable to retrieve market data for a plurality of risk reversals for a currency pair, determine a currency in which to quote skew for each of the risk reversals at a first time, determine that there has been a change in skew, and cause an interface screen to be displayed at least one of the other computing devices with a listing comprising the first and second risk reversals, the market data, and an indication of the change in skew of the at least one of the risk reversals.