Allergens of alder pollen and applications thereof
    5.
    发明授权
    Allergens of alder pollen and applications thereof 失效
    der粉花粉过敏原及其应用

    公开(公告)号:US5693495A

    公开(公告)日:1997-12-02

    申请号:US847010

    申请日:1992-06-01

    摘要: This invention provides recombinant DNA molecules which code for polypeptides that exhibit the antigenicity of an Aln g I allergen of alder, Alnus sp., of a Cor a I allergen of hazel or of a Bet v I allergen of birch and other plants of the order Fageles, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. In addition, methods are described for using the polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of allergic diseases.

    摘要翻译: PCT No.PCT / EP91 / 01479 371日期:1992年6月1日 102(e)日期1992年6月1日PCT 1991年8月6日PCT PCT。 出版物WO92 / 02621 日本1992年2月20日本发明提供重组DNA分子,其编码多肽,其表现出榛子al an an a a a a haz haz haz haz of of of of and and and and and and and and and and and and and and and and and and and and and 对于包含其至少一个表位的多肽,以及在严格条件下与这些DNA序列杂交或通过遗传密码的简并性可从这些序列衍生的核酸,其它植物的Fageles序列。 此外,描述了使用由这些DNA分子编码的多肽及其在过敏性疾病的诊断或治疗中的用途的方法。

    Birch pollen allergen P14 for diagnosis and therapy of allergic diseases
    7.
    发明授权
    Birch pollen allergen P14 for diagnosis and therapy of allergic diseases 失效
    桦木花粉过敏原P14用于诊断和治疗过敏性疾病

    公开(公告)号:US5583046A

    公开(公告)日:1996-12-10

    申请号:US846992

    申请日:1992-06-06

    CPC分类号: C07K1/22 C07K14/415 A61K38/00

    摘要: The invention provides recombinant DNA molecules which code for proteins or polypeptides that exhibit the antigenicity of a P14 allergen of birch Betula verrucosa and other plants of the order Fagales, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. A method is provided that permits purification of P14 allergens or cross-reactive allergens by means of binding to poly(L-proline). In addition, methods are described for making the proteins and polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of allergic diseases.

    摘要翻译: PCT No.PCT / EP91 / 01513 Sec。 371日期:1992年6月6日 102(e)日期1992年6月6日PCT 1991年8月9日PCT PCT。 公开号WO92 / 03551 日期1992年3月5日本发明提供重组DNA分子,其编码表现出白桦桦木的P14变应原和Fagales级别的其它植物的抗原性的蛋白质或多肽,并且对于包含其至少一个表位的多肽以及 在严格条件下与这些DNA序列杂交的核酸或通过遗传密码的简并性从这样的序列衍生。 提供了通过结合聚(L-脯氨酸)来纯化P14变应原或交叉反应性变应原的方法。 此外,描述了制备由这些DNA分子编码的蛋白质和多肽及其在过敏性疾病的诊断或治疗中的用途的方法。

    Materials and methods for identifying genes and/or agents that alter replicative lifespan
    9.
    发明授权
    Materials and methods for identifying genes and/or agents that alter replicative lifespan 失效
    用于鉴定改变复制寿命的基因和/或代理的材料和方法

    公开(公告)号:US07618774B2

    公开(公告)日:2009-11-17

    申请号:US10790456

    申请日:2004-03-01

    IPC分类号: C12Q1/68 C12N1/16 C12N1/18

    摘要: Recombinant materials, including DNA constructs, expression vectors, and host cells, and methods of identifying an environmental stimulus or a gene that alters the lifespan of an organism are identified. The recombinant DNA constructs include first and second chimeric genes that both encode substantially the same protein that is required for yeast replication, the first chimeric gene containing a promoter responsive to growth medium conditions and the second chimeric gene containing a promoter operable in mother cells but not daughter cells.

    摘要翻译: 鉴定重组材料,包括DNA构建体,表达载体和宿主细胞,以及识别改变生物体寿命的环境刺激或基因的方法。 重组DNA构建体包括第一和第二嵌合基因,其编码酵母复制所需的基本上相同的蛋白质,第一嵌合基因含有对生长培养基条件有响应的启动子,第二嵌合基因含有可在母细胞中可操作的启动子 女儿细胞。

    METHODS AND SYSTEMS FOR TRADING OPTIONS AND OTHER DERIVATIVES
    10.
    发明申请
    METHODS AND SYSTEMS FOR TRADING OPTIONS AND OTHER DERIVATIVES 审中-公开
    交易方案和其他衍生物的方法和系统

    公开(公告)号:US20090192930A1

    公开(公告)日:2009-07-30

    申请号:US12197734

    申请日:2008-08-25

    IPC分类号: G06Q40/00

    CPC分类号: G06Q40/04 G06Q40/00

    摘要: In at least one aspect of the invention, systems are provided that comprise at least one computing device coupled to a plurality of other computing devices that are operable to retrieve market data for a plurality of risk reversals for a currency pair, determine a currency in which to quote skew for each of the risk reversals at a first time, determine that there has been a change in skew, and cause an interface screen to be displayed at least one of the other computing devices with a listing comprising the first and second risk reversals, the market data, and an indication of the change in skew of the at least one of the risk reversals.

    摘要翻译: 在本发明的至少一个方面,提供了包括耦合到多个其他计算设备的至少一个计算设备的系统,所述计算设备可操作以检索用于货币对的多个风险反转的市场数据,确定其中 为了首次报告每个风险逆转的偏差,确定偏差发生了变化,并且使得界面屏幕显示至少一个其他计算设备,其中包括第一和第二风险反转的列表 ,市场数据,以及风险反转中的至少一个的偏差变化的指示。