公开(公告)号：US20140296666A1

公开(公告)日：2014-10-02

申请号：US14304690

申请日：2014-06-13

Applicant: GIVEN IMAGING LTD.

Inventor： ELISHA RABINOVITZ ,  Zvika GILAD ,  Amit PASCAL ,  Yaniv BIRNBOIM ,  Gavriel J. IDDAN ,  Daniel GAT ,  Hagai KRUPNIK ,  Ori BRAUN ,  Dan ROTTENBERG ,  Omer SHEZIFI ,  Yosi PESIS ,  Dima PINHASOV ,  Evgeny KAPILOV ,  Nir LILACH ,  Eliahu ELIACHAR ,  Oren COHEN ,  Daniel GAMZU

IPC: A61B5/1459

CPC classification number: A61B5/1459 ,  A61B1/041 ,  A61B1/063 ,  A61B1/0684 ,  A61B5/0084 ,  A61B5/073

Abstract: In-vivo devices, systems and methods for the detection of blood within in-vivo bodily fluids. The methods include irradiating in-vivo fluids passing through a gap in a housing of an in-vivo device introduced to the GI tract of a subject with a plurality of illumination sources positioned on a first side of a gap; detecting with at least one light detector positioned on the opposite side of the gap and facing the illumination sources, light irradiated by the illumination sources; transmitting a plurality of values representing the light detected over time; converting these values to blood concentration values over time, and comparing the blood concentration values to a predetermined threshold value. Based on the comparison, the method includes determining the type of bleeding profile, such that if a plurality of blood concentration values measured consecutively is above the threshold value, the bleeding profile indicates bleeding.

Abstract translation: 用于检测体内体液内的血液的体内装置，系统和方法。 所述方法包括：照射通过定位在间隙的第一侧上的多个照明源的通过被导入到对象的胃肠道的体内装置的壳体中的间隙的体内流体; 用位于所述间隙的相对侧上并且面对所述照明源的至少一个光检测器检测由所述照明源照射的光; 发送表示随时间检测到的光的多个值; 将这些值随时间转换为血液浓度值，并将血液浓度值与预定阈值进行比较。 基于比较，该方法包括确定出血分布的类型，使得如果连续测量的多个血液浓度值高于阈值，则出血分布指示出血。

公开(公告)号：US20170196615A1

公开(公告)日：2017-07-13

申请号：US15468471

申请日：2017-03-24

Applicant: GIVEN IMAGING LTD.

Inventor： Ori BRAUN ,  Gavriel J. Iddan ,  Eyal Kochavi ,  Elisha Rabinovitz ,  Zvika Gilad

IPC: A61B18/02

CPC classification number: A61B18/0218 ,  A61B1/00082 ,  A61B1/00087 ,  A61B1/00091 ,  A61B1/00094 ,  A61B1/015 ,  A61B1/018 ,  A61B1/2736 ,  A61B18/02 ,  A61B2018/0022 ,  A61B2018/00238 ,  A61B2018/00482 ,  A61B2018/00577 ,  A61B2018/00982 ,  A61B2018/0212

Abstract: A device for cryotherapy treatment of gastrointestinal lesions includes a cooling member that may be attached to a first tube for pressurizing cryogenic fluid through the tube and into the cooling member through nozzles located at the distal end of the first tube. A second tube may be attached to the cooling member for evacuating the cryogenic fluid from within the cooling member, following the fluid's expansion once it exits the first tube. The cryotherapy device may be attached to an endoscope such that the first tube may be passed through the endoscope's working channel, while the second tube may be passed along the endoscope's circumference. The cryotherapy device may further comprise securing means attached to the first tube, for securing the first tube to the endoscope's working channel, thus preventing free rotation of the cryotherapy device within the endoscope, relative to the rotation of the endoscope. In addition, the securing means assist in maintaining a constant and known location of the nozzles relative to the distal end of the endoscope.

公开(公告)号：US20160287309A1

公开(公告)日：2016-10-06

申请号：US15183601

申请日：2016-06-15

Applicant: GIVEN IMAGING LTD.

Inventor： Ori BRAUN ,  Gavriel J. Iddan ,  Eyal Kochavi ,  Elisha Rabinovitz ,  Zvika Gilad

IPC: A61B18/02 ,  A61B1/273 ,  A61B1/018

CPC classification number: A61B18/0218 ,  A61B1/00082 ,  A61B1/00087 ,  A61B1/00091 ,  A61B1/00094 ,  A61B1/015 ,  A61B1/018 ,  A61B1/2736 ,  A61B18/02 ,  A61B2018/0022 ,  A61B2018/00238 ,  A61B2018/00482 ,  A61B2018/00577 ,  A61B2018/00982 ,  A61B2018/0212

Abstract: A device for cryotherapy treatment of gastrointestinal lesions includes a cooling member that may be attached to a first tube for pressurizing cryogenic fluid through the tube and into the cooling member through nozzles located at the distal end of the first tube. A second tube may be attached to the cooling member for evacuating the cryogenic fluid from within the cooling member, following the fluid's expansion once it exits the first tube. The cryotherapy device may be attached to an endoscope such that the first tube may be passed through the endoscope's working channel, while the second tube may be passed along the endoscope's circumference. The cryotherapy device may further comprise securing means attached to the first tube, for securing the first tube to the endoscope's working channel, thus preventing free rotation of the cryotherapy device within the endoscope, relative to the rotation of the endoscope. In addition, the securing means assist in maintaining a constant and known location of the nozzles relative to the distal end of the endo scope.

Abstract translation: 用于冷冻治疗胃肠损伤的装置包括冷却构件，该冷却构件可以附接到第一管，用于通过管加压低温流体并通过位于第一管的远端的喷嘴进入冷却构件。 第二管可以附接到冷却构件，用于从冷却构件内部排出低温流体，一旦其离开第一管，流体膨胀。 冷冻治疗装置可以附接到内窥镜，使得第一管可以通过内窥镜的工作通道，而第二管可以沿着内窥镜的圆周通过。 冷冻治疗装置还可以包括附接到第一管的固定装置，用于将第一管固定到内窥镜的工作通道，从而防止冷冻治疗装置相对于内窥镜的旋转在内窥镜内的自由旋转。 此外，固定装置有助于保持喷嘴相对于内窥镜远端的恒定且已知的位置。