摘要:
The present invention relates to specific synergistic active skin- and/or hair-lightening and/or senile keratosis-reducing (cosmetic or pharmaceutical) preparations comprising a mixture comprising or consisting of a) a tyrosinase-inhibiting amount of one or more compounds of the formula 1: wherein: R1 is hydrogen, methyl, straight-chain or branched alkyl having 2-4 C atoms, OH or halogen, R2 is hydrogen, methyl or straight-chain or branched alkyl having 2-5 C atoms, R3 is methyl or straight-chain or branched alkyl having 2-5 C atoms, and R4 and R5 are, independently of one another hydrogen, methyl, straight-chain or branched alkyl having 2-5 C atoms, OH or halogen and b) a skin- and/or hair lightening and/or senile keratosis-reducing amount of one or more compounds selected from the group consisting of (i) chelating agents, (ii) phenolic derivatives, plant extracts with an amount of phenolic derivatives and (iii) organic acid derivatives as well as uses thereof.
摘要:
The present invention relates to specific (cosmetic) formulations for improving the bioavailability and activity of skin- or hair-lightening or senile keratosis-reducing diphenylmethane derivatives (tyrosinase inhibitors) of the following formula 1:
摘要:
The present invention relates primarily to a cosmetic and/or pharmaceutical preparation comprising of consisting of one or more phenolic compounds of the formula (I) where for formula (I) it is the case that: R1, R2, R3, R4 and R5 are independently of one another hydrogen, halogen, an OH group, methyl or a linear or branched alkyl having 2, 3, 4 or 5 C atoms, with 1, 2 or 3 different radicals from the group R1, R2, R3, R4 and R5 simultaneously representing an OH group, R6 and R7 are independently of one another hydrogen, methyl or a linear or branched alkyl having 2, 3, 4 or 5 C atoms, n is an integer from 0 to 20 and R8 is methyl or a linear or branched alkyl having 2 or 3 C atoms, a cycloalkyl having 3, 4, 5, 6 or 7 C atoms or a phenyl and one or more compounds of the formula (II) where for formula (II) it is the case that: R9, R10, R11 and R12 independently of one another are hydrogen, methyl, an OH group or a group —O—R13 and R13 is methyl or a linear or branched alkyl having 2, 3, 4, 5, 6, 7, 8, 9 or 10 C atoms, and to uses of compounds of the formula (II) for stabilizing compounds of the formula (I), and also to methods of stabilizing compounds of the formula (I).
摘要:
The use of a compound having formula (I) is described as an agent for the browning of skin or hair, Formula (I) wherein: R1 and R2 are mutually independently H, OH, C1-C10-alkyl, C1-C10-O-alkyl or O-prenyl, R3 is H, OH, O-glucose or O-rhamnose and R4 is a monosaccharide radical or an oligosaccharide radical having 2, 3, 4 or 5 carbohydrate units, with the proviso that the compound having formula (I) is not used in the form of a preparation based on Citrus auranitium dulcis.
摘要:
The present invention relates to the cosmetic, dermatological or pharmaceutical (therapeutic) use of compounds of formula (I) or a cosmetically acceptable salt of a compound of formula (I) or a mixture containing two or more of these compounds or the salts thereof wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that a 3 to 8 membered ring is formed, for the lightening of skin and/or hair. The invention further relates to compositions and cosmetic, dermatological or pharmaceutical preparations (compositions) comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition for lightening human skin and/or hair and to certain novel compounds of formula (I).
摘要翻译:本发明涉及式(I)化合物或式(I)化合物的化妆品可接受的盐或包含两种或更多种这些化合物或其盐的混合物的化妆品,皮肤病学或药学(治疗)用途,其中 R 1表示氢或碳原子数为1〜14的有机基团,R 2表示碳原子数1〜14的有机基团,且R 1和R 2中任选具有共价键,优选形成3〜8元环 ,用于减轻皮肤和/或头发。 本发明还涉及包含一种或多种适合于减轻人类皮肤和/或头发的相应方法的式(I)化合物的组合物和化妆品,皮肤病学或药物制剂(组合物)。 本发明还涉及作为药物的式(I)化合物,其用于制备用于减轻人类皮肤和/或头发的药物组合物和某些新的式(I)化合物的用途。
摘要:
The present invention relates to the cosmetic, dermatological or pharmaceutical (therapeutic) use of compounds of formula (I) or a cosmetically acceptable salt of a compound of formula (I) or a mixture containing two or more of these compounds or the salts thereof wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that a 3 to 8 membered ring is formed, for the lightening of skin and/or hair. The invention further relates to compositions and cosmetic, dermatological or pharmaceutical preparations (compositions) comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition for lightening human skin and/or hair and to certain novel compounds of formula (I).
摘要翻译:本发明涉及式(I)化合物或式(I)化合物的化妆品可接受的盐或包含两种或更多种这些化合物或其盐的混合物的化妆品,皮肤病学或药学(治疗)用途,其中 R 1表示氢或碳原子数为1〜14的有机基团,R 2表示碳原子数1〜14的有机基团,且R 1和R 2中任选具有共价键,优选形成3〜8元环 ,用于减轻皮肤和/或头发。 本发明还涉及包含一种或多种适合于减轻人类皮肤和/或头发的相应方法的式(I)化合物的组合物和化妆品,皮肤病学或药物制剂(组合物)。 本发明还涉及作为药物的式(I)化合物,其用于制备用于减轻人类皮肤和/或头发的药物组合物和某些新的式(I)化合物的用途。
摘要:
The present invention relates primarily to the use of locust tree (Gleditsia) wood or heartwood extracts as anti-cellulite active substances. The present invention further relates to certain locust-tree wood extracts and mixtures containing locust-tree wood extracts and corresponding cosmetic, dermatological or pharmaceutical preparations, which are suitable in particular for the prevention and treatment of cellulite in humans.
摘要:
A cellular rubber profile for the sealing of two components which cooperate with one another is disclosed. The profile has a black base structure and a non-black overlay structure which is co-extruded with the base structure. The overlay structure overlies the base structure in the manner of a cap. Opposite the overlay structure the profile has a foot portion with lateral protuberances.
摘要:
The present invention relates primarily to the use of locust tree (Gleditsia) wood or heartwood extracts as anti-cellulite active substances. The present invention further relates to certain locust-tree wood extracts and mixtures containing locust-tree wood extracts and corresponding cosmetic, dermatological or pharmaceutical preparations, which are suitable in particular for the prevention and treatment of cellulite in humans.