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公开(公告)号：US06234771B1
公开(公告)日：2001-05-22
申请号：US09322354
申请日：1999-05-28
IPC分类号： F04B1700
CPC分类号： F04B17/03 , F04B2203/0213
摘要： A precision pumping device for aspirating and dispensing different volumes of fluid is presented. The precision pumping device comprises a housing with integral anti-rotation guides, a stepper motor which drives a fine pitch lead screw, a coupling for linking the piston to the leadscrew, an anti-backlash leadscrew follower, a split hub clamp nut, and a nut for securing the chamber to the housing. A seal is provided which seals around the piston and against the chamber, as is an o-ring that is set into a groove in the chamber and seals against a flange of the seal. The precision pumping device further includes a piston and a chamber for receiving at least a portion of the piston therein. The piston and chamber are of different sizes for aspirating and dispensing different volumes of fluid. The chamber can include a single port or multiple ports. Due to the self-aligning features and the reduced number of parts, the pump can be easily changed from aspirating and dispensing a first volume of fluid to aspirating and dispensing a second volume of fluid.
摘要翻译： 提出了一种用于吸取和分配不同体积流体的精密抽吸装置。 精密泵送装置包括具有整体防旋转引导件的壳体，驱动细间距丝杆的步进马达，用于将活塞连接到丝杠的联接器，反间隙丝杠从动件，分离式轮毂夹紧螺母和 用于将腔室固定到壳体的螺母。 提供密封件，密封件围绕活塞密封并且抵靠腔室，O形环也被设置在腔室中的凹槽中并且密封抵靠密封件的凸缘。 精密泵送装置还包括活塞和用于容纳活塞的至少一部分的腔室。 活塞和腔室具有不同的尺寸，用于吸取和分配不同体积的流体。 该腔室可以包括单个端口或多个端口。 由于自对准特征和部件数量的减少，泵可以容易地从抽吸和分配第一体积的流体改变以吸取和分配第二体积的流体。
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公开(公告)号：US5735387A
公开(公告)日：1998-04-07
申请号：US502610
申请日：1995-07-14
CPC分类号： G01N35/04 , G01N2035/0477 , G01N35/026 , Y10T436/114165
摘要： A magnetic conveyor system for transporting test samples in tubes disposed in a sample rack having a magnetic or magnetically attractive region is described. The magnetic conveyor system includes a drive system, a magnet coupled to the drive system and movable in response to the drive system and a tray having a first surface adapted to receive the sample rack. The magnet is spaced a predetermined distance from the first surface of the tray such that the magnet provides a magnetic force at the surface of the tray. The magnetic force engages the magnetically attractive region of the sample rack disposed on the tray to thereby move the sample rack along the first surface of the tray in response to movement of the drive system. When the tray reaches the end of the rack it is moved onto a processing queue tray where it is available for test purposes. A barcode reader reads a bar code on each test sample as it is placed on the process queue to identify one or more tests to perform. When all samples have received the individual tests the rack exits to an output queue for disposal. When a test must be made on an immediate basis out of normal processing order a sample rack can be inserted into the process queue via a priority rack feed. In the indicated manner, testing can continue without interruption as new racks are added and completed racks removed.
摘要翻译： 描述了一种磁性输送系统，用于将测试样品输送到设置在具有磁性或磁吸引区域的样品架中的管中。 磁性输送系统包括驱动系统，耦合到驱动系统的磁体，并可响应于驱动系统而移动;以及托盘，其具有适于接收样品架的第一表面。 磁体与托盘的第一表面隔开预定的距离，使得磁铁在盘的表面提供磁力。 磁力接合设置在托盘上的样品架的磁吸引区域，从而响应于驱动系统的移动沿着托盘的第一表面移动样品架。 当托盘到达机架的末端时，将其移动到处理队列托盘中，以供测试。 条形码读取器读取每个测试样本上的条形码，因为它放置在进程队列中，以识别要执行的一个或多个测试。 当所有样品都接收到单独的测试时，机架退出到输出队列进行处置。 必须在正常处理顺序的基础上进行测试时，可以通过优先机架进给将样品架插入进程队列。 以指示的方式，随着添加新的机架和完成的机架被移除，测试可以不间断地继续。
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公开(公告)号：US5720377A
公开(公告)日：1998-02-24
申请号：US502653
申请日：1995-07-14
申请人： David J. Lapeus , Michael Ballash
发明人： David J. Lapeus , Michael Ballash
CPC分类号： B01L9/06 , G01N35/04 , B01L2200/025 , G01N2035/00752 , G01N2035/0467 , G01N2035/0477 , G01N35/026
摘要： A magnetic conveyor system for transporting test samples in tubes disposed in a sample rack having a magnetic or magnetically attractive region is described. The magnetic conveyor system includes a drive system, a magnet coupled to the drive system and movable in response to the drive system and a tray having a first surface adapted to receive the sample rack. The magnet is spaced a predetermined distance from the first surface of the tray such that the magnet provides a magnetic force at the surface of the tray. The magnetic force engages the magnetically attractive region of the sample rack disposed on the tray to thereby move the sample rack along the first surface of the tray in response to movement of the drive system. When the tray reaches the end of the rack it is moved onto a processing queue tray where it is available for test purposes. A barcode reader reads a bar code on each test sample as it is placed on the process queue to identify one or more tests to perform. When all samples have received the individual tests the rack exits to an output queue for disposal. When a test must be made on an immediate basis out of normal processing order a sample rack can be inserted into the process queue via a priority rack feed. In the indicated manner, testing can continue without interruption as new racks are added and completed racks removed.
摘要翻译： 描述了一种磁性输送系统，用于将测试样品输送到设置在具有磁性或磁吸引区域的样品架中的管中。 磁性输送系统包括驱动系统，耦合到驱动系统的磁体，并可响应于驱动系统而移动;以及托盘，其具有适于接纳样架的第一表面。 磁体与托盘的第一表面隔开预定的距离，使得磁铁在盘的表面提供磁力。 磁力接合设置在托盘上的样品架的磁吸引区域，从而响应于驱动系统的移动沿着托盘的第一表面移动样品架。 当托盘到达机架的末端时，将其移动到处理队列托盘中，以供测试。 条形码读取器读取每个测试样本上的条形码，因为它放置在进程队列中，以识别要执行的一个或多个测试。 当所有样品都接收到单独的测试时，机架退出到输出队列进行处置。 必须在正常处理顺序的基础上进行测试时，可以通过优先机架进给将样品架插入进程队列。 以指示的方式，随着添加新的机架和完成的机架被移除，测试可以不间断地继续。
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公开(公告)号：USD428497S
公开(公告)日：2000-07-18
申请号：US84655
申请日：1998-03-06
申请人： David J. Lapeus , Michael Ballash
设计人： David J. Lapeus , Michael Ballash
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公开(公告)号：USD413391S
公开(公告)日：1999-08-31
申请号：US83143
申请日：1998-02-05
申请人： David J. Lapeus , Michael Ballash
设计人： David J. Lapeus , Michael Ballash
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公开(公告)号：US5674047A
公开(公告)日：1997-10-07
申请号：US501855
申请日：1995-07-13
申请人： David J. Lapeus , James P. Polaniec
发明人： David J. Lapeus , James P. Polaniec
CPC分类号： B01L9/543 , G01N35/10 , G01N2035/0425
摘要： In a system for installing, from a supply of disposable probe tips, one such probe tip on a probe for each sample by an automated fluid analyzer system and for removing the tip after each use to allow a fresh tip to be installed, a mechanism for making a fresh supply of tips available in a carrier tray and for receiving and disposing of empty carrier trays. Multiple probe tip trays, each having a base, a lid, and holding an array of tips are stacked within a chute of the mechanism. A pair of arms are swung up from a substantially vertical position to a horizontal position beneath the chute. An associated latch engages the lid of the lowermost tray within the chute while tray guides, which hold the trays within the chute, separate to release the lowermost tray onto the pair of arms. A delivery rack associated with the analyzer system receives the lowermost tray base from the pair of arms by engaging the tray base with a pair of clips. The rack then removes the base, and the probes thereon, to the analyzer system. The pair of arms meanwhile lower and dump the lid into a waste receptacle or disposal chute. The delivery rack thereafter returns an empty base to the parallel arms, which similarly dump empty base into the waste receptacle or disposal chute. The cycle is repeated by removing the next tray from the chute.
摘要翻译： 在用于通过自动化流体分析仪系统从一次性探针尖端的一次性探针尖端的一个这样的探针尖端安装在每个样品的探针上并且在每次使用之后移除尖端以允许安装新的尖端的系统中， 在托盘中提供新鲜的提示，并接收和处理空托架。 多个探针尖端托盘，每个具有底座，盖子和保持尖端阵列堆叠在机构的滑槽内。 一对臂从大致垂直的位置向上摆动到滑槽下方的水平位置。 相关联的闩锁接合滑槽内的最下面的托盘的盖子，同时将托盘保持在滑槽内的托盘引导件被分离以将最下面的托盘释放到一对臂上。 与分析器系统相关联的输送架通过将托盘基座与一对夹子接合而从一对臂接收最下面的托盘基座。 然后，机架将基座和其上的探头移除到分析器系统。 一对手臂同时下降并将盖子倒入废物容器或处理槽中。 然后，送货架将空的基座返回到平行臂，这样同样地将空的基座倾倒到废物容器或处理槽中。 通过从滑槽中移除下一个托盘来重复该循环。
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公开(公告)号：US08865457B2
公开(公告)日：2014-10-21
申请号：US12077193
申请日：2008-03-17
申请人： Jim Polaniec , David J. Lapeus , Tim Greszler , Frank Klingshirn , Chris Sturges , Matt Schmidt
发明人： Jim Polaniec , David J. Lapeus , Tim Greszler , Frank Klingshirn , Chris Sturges , Matt Schmidt
CPC分类号： B01L7/52 , B01L2200/147 , B01L2300/0829 , B01L2300/1822 , B01L2300/1844 , B01L2300/185 , F25B21/04
摘要： Devices and systems for active thermal control of sample holding devices for bDNA testing, polymerase chain reaction testing, chemiluminescent immuno-assay testing, and so forth. The thermal control subsystem includes a fluidic circuit, first and second heater assemblies, a centrifugal pump, and a heat exchange device. The first and second heater assemblies include a heat removal device and a controllable thermo-electric device. One or both of the heater assemblies can include a heat spreader. A controller actively controls the pump, the heat removal device, and the thermo-electric devices, to thermally-control sample-containing vessels retained in the holding device.
摘要翻译： 用于bDNA测试，聚合酶链反应测试，化学发光免疫分析测试等的样品保持装置的主动热控制的装置和系统。 热控制子系统包括流体回路，第一和第二加热器组件，离心泵和热交换装置。 第一和第二加热器组件包括散热装置和可控热电装置。 一个或两个加热器组件可以包括散热器。 控制器主动地控制泵，除热装置和热电装置，以热控制保持在保持装置中的含样品的容器。
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公开(公告)号：US20080227186A1
公开(公告)日：2008-09-18
申请号：US12077193
申请日：2008-03-17
申请人： Jim Polaniec , David J. Lapeus , Tim Greszler , Frank Klingshirn , Chris Sturges , Matt Schmidt
发明人： Jim Polaniec , David J. Lapeus , Tim Greszler , Frank Klingshirn , Chris Sturges , Matt Schmidt
IPC分类号： C12M1/02
CPC分类号： B01L7/52 , B01L2200/147 , B01L2300/0829 , B01L2300/1822 , B01L2300/1844 , B01L2300/185 , F25B21/04
摘要： Devices and systems for active thermal control of sample holding devices for bDNA testing, polymerase chain reaction testing, chemiluminescent immuno-assay testing, and so forth. The thermal control subsystem includes a fluidic circuit, first and second heater assemblies, a centrifugal pump, and a heat exchange device. The first and second heater assemblies include a heat removal device and a controllable thermo-electric device. One or both of the heater assemblies can include a heat spreader. A controller actively controls the pump, the heat removal device, and the thermo-electric devices, to thermally-control sample-containing vessels retained in the holding device.
摘要翻译： 用于bDNA测试，聚合酶链反应测试，化学发光免疫分析测试等的样品保持装置的主动热控制的装置和系统。 热控制子系统包括流体回路，第一和第二加热器组件，离心泵和热交换装置。 第一和第二加热器组件包括散热装置和可控热电装置。 一个或两个加热器组件可以包括散热器。 控制器主动地控制泵，除热装置和热电装置，以热控制保持在保持装置中的含样品的容器。
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