公开(公告)号：US20210030691A1

公开(公告)日：2021-02-04

申请号：US17076435

申请日：2020-10-21

Applicant: HOWARD UNIVERSITY

Inventor： Preethi Chandran

IPC: A61K9/51 ,  A61K38/00 ,  A61K47/69 ,  A61K47/59 ,  C08G73/02 ,  A61K47/54 ,  A61K9/00

Abstract: Non-viral delivery platforms are provided for facilitating transport of molecules across cell membranes. In some forms, DNA nanoshells capable of transporting cargo molecules are formed, and may be formed in order to surround a variety of materials for a variety of purposes.

公开(公告)号：US12161985B2

公开(公告)日：2024-12-10

申请号：US17307515

申请日：2021-05-04

Applicant: HOWARD UNIVERSITY

Inventor： Mohsen Mosleh ,  Mousab Ahmed ,  Preethi Chandran ,  Marjan Alaghmand

IPC: C10M105/12 ,  B01J13/00 ,  C10M115/04 ,  C10M125/02 ,  C10M125/04 ,  C10M125/20 ,  C10M125/22 ,  C10M171/02 ,  C10M171/06 ,  B82Y40/00 ,  C10N20/06 ,  C10N50/00

Abstract: An organogel including a base fluid, cetyl alcohol, and a gelling agent provided in an amount to cause the fluid to change from a liquid state to a gelled state at temperatures below at least 25° C. A nanofluid including an organogel and a nanoparticle component which permits the nanofluid to change from a liquid state to a gelled state at temperatures below at least 25° C., the gelled state helping to maintain the nanoparticle component suspended throughout the base fluid; and a method for preparing a gelled nanofluid.

公开(公告)号：US12109316B2

公开(公告)日：2024-10-08

申请号：US17076435

申请日：2020-10-21

Applicant: HOWARD UNIVERSITY

Inventor： Preethi Chandran

IPC: A61K9/51 ,  A61K9/00 ,  A61K38/00 ,  A61K47/54 ,  A61K47/59 ,  A61K47/69 ,  C08G73/02

CPC classification number: A61K9/5146 ,  A61K9/0019 ,  A61K9/513 ,  A61K9/5161 ,  A61K9/5192 ,  A61K38/00 ,  A61K47/549 ,  A61K47/59 ,  A61K47/6925 ,  C08G73/02

Abstract: Non-viral delivery platforms are provided for facilitating transport of molecules across cell membranes. In some forms, DNA nanoshells capable of transporting cargo molecules are formed, and may be formed in order to surround a variety of materials for a variety of purposes.

公开(公告)号：US11707534B2

公开(公告)日：2023-07-25

申请号：US16310608

申请日：2017-06-23

Applicant: HOWARD UNIVERSITY

Inventor： Preethi Chandran

IPC: A61K47/69 ,  A61K9/00 ,  A61K48/00 ,  C08G73/02 ,  C08J3/24 ,  C08L79/02 ,  C08J3/12 ,  C08J3/075 ,  C08K5/00 ,  C08K5/07 ,  B82Y5/00 ,  C08L101/14

CPC classification number: A61K47/6935 ,  A61K9/0004 ,  A61K9/0053 ,  A61K48/0041 ,  C08G73/0206 ,  C08J3/075 ,  C08J3/12 ,  C08J3/24 ,  C08J3/246 ,  C08L79/02 ,  A61K48/0033 ,  B82Y5/00 ,  C08G2210/00 ,  C08J2300/14 ,  C08J2379/02 ,  C08K5/0025 ,  C08K5/07 ,  C08L101/14

Abstract: Covalently linked linear polyethylenimine (PEI) clusters are provided that change conformation depending upon changes in counterion concentrations. The structures may be used for the storage, delivery, and/or transport of substances.