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公开(公告)号：US20220002738A1
公开(公告)日：2022-01-06
申请号：US17293109
申请日：2019-11-18
Applicant: Jingping ZHONG , BASF SE
Inventor： Jingping Zhong , Xuqiu Tan , Melissa Ann Scranton , Daphne Li
IPC: C12N15/81 , C12P21/02 , C12N1/16 , C12N15/113
Abstract: The present invention relates to a recombinant yeast cell for high yield protein expression. The invention further relates to cell culture involving the recombinant yeast cell, a method for preparing protein involving culturing the recombinant yeast cell and a use of the recombinant yeast cell.
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Patent Agency Ranking2.发明授权Receptor-like protein kinase, RKN, and method of use for increasing growth and yield in plants 失效受体样蛋白激酶，RKN和用于增加植物生长和产量的方法
公开(公告)号：US6156954A
公开(公告)日：2000-12-05
申请号：US120855
申请日：1998-07-21
Applicant: Jingping Zhong , Qun Zhu , Christopher J. Lamb
Inventor： Jingping Zhong , Qun Zhu , Christopher J. Lamb
IPC: A01H5/00 , C07K14/415 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/09 , C12N15/29 , C12N15/82 , C12N15/84 , C12N5/04 , C12N15/52 , A01H5/10
CPC classification number: C12N9/1205 , C07K14/415 , C12N15/8261
Abstract: The present invention is based on the discovery that increased growth and yield in plants can be achieved by elevating the level of receptor-like protein kinase (RKN), a member of the receptor-like protein kinase (RLK) family. RKN polypeptide and polynucleotides encoding RKN polypeptide are provided, as are RKN expression control sequences. Also included are methods of producing a genetically modified plant characterized as having increased growth and yield as compared to a corresponding wild-type plant. A method for genetically modifying a plant cell such that a plant produced form the cell will have a modulated yield is also provided. A method of producing a genetically modified plant characterized as having increased expression of a gene product of interest in its roots as compared to the corresponding wild type plant is also provided. The invention also provides plants, plant tissue, and seeds produced by the genetically modified plants of the invention.
Abstract translation: 本发明基于以下发现：通过提高受体样蛋白激酶（RKN）（受体样蛋白激酶（RLK）家族的成员）的水平，能够增加植物的生长和产量。 提供RKN多肽和编码RKN多肽的多核苷酸，以及RKN表达调控序列。 还包括生产与相应野生型植物相比具有增加的生长和产量的遗传修饰植物的方法。 还提供了用于遗传修饰植物细胞使得从细胞产生的植物具有调制产量的方法。 还提供了一种生产遗传修饰植物的方法，其特征在于与相应的野生型植物相比，其在根中具有增加的感兴趣的基因产物的表达。 本发明还提供由本发明的转基因植物产生的植物，植物组织和种子。
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公开(公告)号：US20210388037A1
公开(公告)日：2021-12-16
申请号：US17293240
申请日：2019-11-18
Applicant: BASF SE
Inventor： Jingping Zhong , Xuqiu Tan , Melissa Ann Scranton
Abstract: The present invention relates to a leader peptide which promotes the secretion of recombinant proteins and a nucleic acid sequence encoding the leader peptide as well as expression cassettes, vectors and host cells comprising this leader sequence. Also disclosed is a method for producing a protein using this leader peptide.
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公开(公告)号：US20210115422A1
公开(公告)日：2021-04-22
申请号：US17051937
申请日：2019-04-24
Applicant: BASF SE
Inventor： Asfia Qureshi , Adrienne Huston Davenport , Xuqiu Tan , Oliver Spangenberg , Amanda Rae Logue , Janina Berndt , Tong Li , Stefan Seemayer , Hans Wolfgang Hoeffken , Jingping Zhong
Abstract: Engineered variant polypeptides having amylase enzyme activity, compositions comprising the enzymes, and methods of making and using the enzymes. The genetically engineered amylase enzymes are useful in many different applications such as laundry detergents, dish washing detergents, and cleaning products for homes, industry, vehicle care, baking, animal feed, pulp and paper processing, starch processing, and ethanol production.
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公开(公告)号：US20240084084A1
公开(公告)日：2024-03-14
申请号：US18512485
申请日：2023-11-17
Applicant: BASF SE
Inventor： Xuqiu Tan , Ruorong Cai , Jingping Zhong , Melissa Ann Scranton , Michael Speer
CPC classification number: C08J5/18 , B29C48/022 , B29C48/08 , B29C65/02 , B65B9/023 , C08L23/0815 , B29K2023/06 , B29L2031/7128
Abstract: A promoter operably linked to a gene encoding a protein is disclosed. The promoter drives expression of the protein in a yeast cell in the absence of methanol. Also disclosed are vectors, host cells and expression systems that include the promoter, as well as methods of using the promoter to express proteins in yeast.
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公开(公告)号：US11866714B2
公开(公告)日：2024-01-09
申请号：US15734682
申请日：2019-06-03
Applicant: BASF SE
Inventor： Xuqiu Tan , Ruorong Cai , Jingping Zhong , Melissa Ann Scranton , Michael Speer
CPC classification number: C12N15/815 , C07K14/39
Abstract: A promoter operably linked to a gene encoding a protein is disclosed. The promoter drives expression of the protein in a yeast cell in the absence of methanol. Also disclosed are vectors, host cells and expression systems that include the promoter, as well as methods of using the promoter to express proteins in yeast.
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