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    METHOD OF ELECTRICALLY DETECTING BIOMOLECULE
    1.
    发明申请
    METHOD OF ELECTRICALLY DETECTING BIOMOLECULE 审中-公开
    电生物分析方法

    公开(公告)号：US20100181209A1

    公开(公告)日：2010-07-22

    申请号：US12637245

    申请日：2009-12-14

    申请人： Kyu-tae YOO ,  Sung-ouk JUNG ,  Jun-hong MIN ,  Ji-na NAMGOONG ,  Soo-hyung CHOI ,  Jeo-young SHIM

    发明人： Kyu-tae YOO ,  Sung-ouk JUNG ,  Jun-hong MIN ,  Ji-na NAMGOONG ,  Soo-hyung CHOI ,  Jeo-young SHIM

    IPC分类号： G01N27/26

    CPC分类号： G01N33/54306

    摘要： Provided is a method of sensing biomolecules using a bioFET, the method including: forming a layer including Au on a gate of the bioFET; forming a probe immobilized on a substrate separated from the gate by a predetermined distance, and a biomolecule having a thiol group (—SH) which is incompletely bonded to the probe; reacting the probe with a sample including a target molecule; and measuring a current flowing in a channel region between a source and a drain of the bioFET.

    摘要翻译： 提供了一种使用bioFET感测生物分子的方法，该方法包括：在bioFET的栅极上形成包含Au的层; 形成固定在与栅极分离预定距离的基板上的探针，以及具有与探针不完全结合的硫醇基（-SH）的生物分子; 使探针与包含靶分子的样品反应; 以及测量在bioFET的源极和漏极之间的沟道区域中流动的电流。

    SENSING SWITCH AND DETECTING METHOD USING THE SAME
    2.
    发明申请
    SENSING SWITCH AND DETECTING METHOD USING THE SAME 有权
    感应开关及其检测方法

    公开(公告)号：US20100329931A1

    公开(公告)日：2010-12-30

    申请号：US12833095

    申请日：2010-07-09

    申请人： Kyu-tae YOO ,  Joon-ho KIM ,  Jun-hong MIN ,  Sung-ouk JUNG ,  Ji-na NAMGOONG ,  Kui-hyun KIM ,  Jeo-young SHIM ,  Kak NAMKOONG

    发明人： Kyu-tae YOO ,  Joon-ho KIM ,  Jun-hong MIN ,  Sung-ouk JUNG ,  Ji-na NAMGOONG ,  Kui-hyun KIM ,  Jeo-young SHIM ,  Kak NAMKOONG

    IPC分类号： G01N27/00

    CPC分类号： G01N33/54373

    摘要： Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.

    摘要翻译： 提供了一种感测开关和使用该感测开关的感测方法。 感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。 目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。

    SENSING SWITCH AND DETECTING METHOD USING THE SAME
    3.
    发明申请
    SENSING SWITCH AND DETECTING METHOD USING THE SAME 有权
    感应开关及其检测方法

    公开(公告)号：US20090170211A1

    公开(公告)日：2009-07-02

    申请号：US12272183

    申请日：2008-11-17

    申请人： Kyu-tae YOO ,  Joon-ho KIM ,  Jun-hong MIN ,  Sung-ouk JUNG ,  Ji-na NAMGOONG ,  Kui-hyun KIM ,  Jeo-young SHIM ,  Kak NAMKOONG

    发明人： Kyu-tae YOO ,  Joon-ho KIM ,  Jun-hong MIN ,  Sung-ouk JUNG ,  Ji-na NAMGOONG ,  Kui-hyun KIM ,  Jeo-young SHIM ,  Kak NAMKOONG

    IPC分类号： G01N27/00

    CPC分类号： G01N33/54373

    摘要： Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.

    摘要翻译： 提供了一种感测开关和使用该感测开关的感测方法。 感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。 目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。

    MICROFLUIDIC DEVICE USING CENTRIFUGAL FORCE AND PUMP TO CONTROL FLUID MOVEMENT, MICROFLUIDIC SYSTEM COMPRISING THE SAME AND METHOD OF MANUFACTURING THE MICROFLUIDIC DEVICE
    6.
    发明申请
    MICROFLUIDIC DEVICE USING CENTRIFUGAL FORCE AND PUMP TO CONTROL FLUID MOVEMENT, MICROFLUIDIC SYSTEM COMPRISING THE SAME AND METHOD OF MANUFACTURING THE MICROFLUIDIC DEVICE 有权
    使用离心力和泵控制流体运动的微流体装置，包括其的微流体系统和制造微流体装置的方法

    公开(公告)号：US20080135101A1

    公开(公告)日：2008-06-12

    申请号：US11869835

    申请日：2007-10-10

    申请人： Hun-joo LEE ,  Nam HUH ,  Soo-suk LEE ,  Sung-ouk JUNG ,  Soo-hyung CHOI

    发明人： Hun-joo LEE ,  Nam HUH ,  Soo-suk LEE ,  Sung-ouk JUNG ,  Soo-hyung CHOI

    IPC分类号： B81B1/00 ,  B21D51/16 ,  G05D7/03

    CPC分类号： G05D7/0694 ,  Y10T29/494 ,  Y10T137/0753 ,  Y10T137/2191 ,  Y10T137/86187

    摘要： The microfluidic device includes a rotatable platform, a plurality of connection ports disposed at a portion of the platform proximate to a shaft connection hole, the plurality of connection ports capable of being connected to an external connector for selectively injecting and discharging fluid and being closed by the connector, a trap chamber disposed at a portion of the platform further away from the shaft connection hole than the plurality of connection ports, the trap chamber including an inlet connected with at least one connection port of the plurality of connection ports, an outlet connected with another connection port of the plurality of connection ports and structures which enlarge a contact area with the fluid and a temporary storage including an inlet connected with the outlet of the trap chamber and an outlet connected with another connection port of the plurality of connection ports.

    摘要翻译： 所述微流体装置包括可旋转平台，多个连接端口，设置在所述平台的靠近轴连接孔的部分处，所述多个连接端口能够连接到外部连接器，用于选择性地注入和排出流体并且由 所述连接器，设置在所述平台的远离所述轴连接孔的所述平台部分处的所述收集室，所述收集室包括与所述多个连接端口中的至少一个连接端口连接的入口，所述入口连接到所述入口 多个连接端口中的另一个连接端口和扩大与流体的接触面积的结构以及包括与捕集室的出口连接的入口的临时存储器和与多个连接端口中的另一连接端口连接的出口。

    METHOD AND KIT FOR POSITIVELY DETECTING TOXIC MATERIAL
    7.
    发明申请
    METHOD AND KIT FOR POSITIVELY DETECTING TOXIC MATERIAL 有权
    用于阳极检测毒性材料的方法和工具包

    公开(公告)号：US20110256570A1

    公开(公告)日：2011-10-20

    申请号：US13155944

    申请日：2011-06-08

    申请人： Jung-im HAN ,  Soo-hyung CHOI ,  Soo-suk LEE ,  Sung-ouk JUNG ,  Joon-shik PARK ,  Ki-eun KIM

    发明人： Jung-im HAN ,  Soo-hyung CHOI ,  Soo-suk LEE ,  Sung-ouk JUNG ,  Joon-shik PARK ,  Ki-eun KIM

    IPC分类号： C12Q1/32 ,  C12Q1/00

    CPC分类号： G01N33/5079 ,  G01N2333/90209

    摘要： A method of positively detecting toxic materials within a sample, the method including contacting sub-mitochondrial particles having competent mitochondrial enzymes formed from inner membranes of mitochondria, an electron donor which transmits electrons to an electron transfer system of the sub-mitochondrial particles and the sample, and forming reaction resultants, adjusting a pH of a pH indicator which change color according to a change in pH, adding the pH indicators to each reaction resultant and identifying color changes of the pH indicator. Also provided is a kit for positively detecting toxic materials within a sample.

    摘要翻译： 一种积极检测样品内的有毒物质的方法，该方法包括使具有由线粒体内膜形成的感受态线粒体酶的亚线粒体颗粒，将电子传递到亚线粒体颗粒的电子转移系统的电子给体和样品 ，并形成反应产物，调节pH指示剂的pH值，根据pH的变化改变颜色，向每个反应产物添加pH指示剂并鉴定pH指示剂的颜色变化。 还提供了用于积极检测样品中有毒物质的试剂盒。

    NUCLEIC ACID CHIP COUPLING SYSTEM AND METHOD OF USE
    9.
    发明申请
    NUCLEIC ACID CHIP COUPLING SYSTEM AND METHOD OF USE 审中-公开
    核酸切片联合系统及其使用方法

    公开(公告)号：US20080248973A1

    公开(公告)日：2008-10-09

    申请号：US12099610

    申请日：2008-04-08

    申请人： Sung-ouk JUNG

    发明人： Sung-ouk JUNG

    IPC分类号： C40B60/00

    CPC分类号： C40B60/14 ,  C40B40/08

    摘要： Disclosed herein is a nucleic acid chip coupling system and a method of operating the nucleic acid chip coupling system. The nucleic acid chip coupling system comprises an upper case, a lower case, and a stirring shaft. The lower case is coupled with the upper case to form a space therein. The stirring shaft is rotatably coupled with one of the upper and lower cases and connected to one side of a wafer so as to rotate the wafer.

    摘要翻译： 本文公开了核酸芯片偶联系统和操作核酸芯片偶联系统的方法。 核酸芯片联接系统包括上壳体，下壳体和搅拌轴。 下壳体与上壳体联接以在其中形成空间。 搅拌轴与上壳体和下壳体中的一个可旋转地连接，并且连接到晶片的一侧以便旋转晶片。