Abstract:
Syringe systems and flow control systems configured to detect information associated with a liquid material are described. The syringe systems may include a syringe body for housing the liquid material and an injector piston for expelling the liquid material out of the syringe through a discharge outlet at a distal end of the syringe body. Components of the syringe, such as an injector piston, may include sensors configured to measure and/or detect a property of the liquid material, such as concentration, pH, or radioactivity. The flow control system may include a pinch valve and a platen arranged about a fluid delivery channel. Flow within the fluid delivery channel may be controlled by increasing (squeezing the fluid delivery channel) or decreasing the distance between the pinch valve and the platen. Components of the flow control system may include detectors configured to detect properties of fluid in the fluid control channel.
Abstract:
Methods and systems for dispensing a fluid using an automated fluid delivery system are disclosed. A pump may be configured to force an aliquot of fluid into a fluid delivery channel. A processor may receive values of a property for the aliquot and the source of the aliquot. The processor may use the values to determine the volume of the aliquot. The determined volume is compared by the processor against an expected volume to establish the amount of fluid being pumped by the pump per unit, such as time or revolutions. The processor controls operation of the pump to dispense a predetermined dose based on the amount of fluid being pumped by the pump per unit.
Abstract:
A device for delivery of a radiopharmaceutical and, in some embodiments, delivery of a pharmaceutical agent are provided herein. A fluid path set comprising a confluence valve, a four-way valve, and one or more tubing sections which are designed to place some combination of a radiopharmaceutical source, a medical fluid source, and a pharmaceutical agent source in sterile fluid communication with a patient or a waste receptacle. Also provided are holders for the fluid path set, and a sterile fluid delivery kit comprising the holder and fluid path set. A fluid delivery system may accept the holder with the fluid path set installed and various sources of radiopharmaceuticals, pharmaceuticals, and medical fluids. The fluid delivery system allows for automated mixing and delivery of exact amounts of these agents to a patient while improving efficiency and safety, and reducing waste.
Abstract:
A valveless pharmaceutical infusion system for delivery of a pharmaceutical, such as a radiopharmaceutical, is described. The device may include two or more roller pumps, a fluid path set including a confidence, and a measuring device for measuring a property of the pharmaceutical. Methods for delivering a pharmaceutical, such as a radiopharmaceutical, using a valveless pharmaceutical infusion system are also describe.