公开(公告)号：US20220003766A1

公开(公告)日：2022-01-06

申请号：US17246360

申请日：2021-04-30

Applicant: Meso Scale Technologies, LLC.

Inventor： Jacob N. WOHLSTADTER ,  George SIGAL ,  Anu MATHEW ,  Anastasia AKSYUK ,  David ROUTENBERG ,  Martin STENGELIN ,  John KENTEN ,  Timothy J. BREAK ,  Seth B. HARKINS ,  Michael TSIONSKY

IPC: G01N33/569 ,  C12Q1/70

Abstract: The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.

公开(公告)号：US20210291168A1

公开(公告)日：2021-09-23

申请号：US17215962

申请日：2021-03-29

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. GLEZER ,  Sudeep KUMAR ,  Pankaj OBEROI ,  George SIGAL ,  Michael TSIONSKY

IPC: B01L3/00 ,  C12Q1/6804 ,  G01N33/68 ,  G01N33/543 ,  C12Q1/6816 ,  C12Q1/6876

Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.

公开(公告)号：US20180154353A1

公开(公告)日：2018-06-07

申请号：US15882914

申请日：2018-01-29

Applicant: MESO SCALE TECHNOLOGIES, LLC

Inventor： Eli N. GLEZER ,  Bandele JEFFREY-COKER ,  Jeffery D. DEBAD ,  Sudeep M. KUMAR ,  George B. SIGAL ,  Gisbert SPIELES ,  Michael TSIONSKY ,  Michael WARNOCK

IPC: B01L3/00 ,  G01N33/543

CPC classification number: B01L3/5025 ,  B01L3/5085 ,  B01L2200/12 ,  B01L2200/16 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/0858 ,  B01L2300/105 ,  G01N33/54366 ,  G01N33/54393 ,  Y10S436/809

Abstract: We describe assay modules (e.g., assay plates, cartridges, multi-well assay plates, reaction vessels, etc.), processes for their preparation, and method of their use for conducting assays. Reagents may be present in free form or supported on solid phases including the surfaces of compartments (e.g., chambers, channels, flow cells, wells, etc.) in the assay modules or the surface of colloids, beads, or other particulate supports. In particular, dry reagents can be incorporated into the compartments of these assay modules and reconstituted prior to their use in accordance with the assay methods. A desiccant material may be used to maintain and stabilize these reagents in a dry state.

公开(公告)号：US20240159746A1

公开(公告)日：2024-05-16

申请号：US18548444

申请日：2022-02-28

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Michael TSIONSKY ,  John KENTEN

IPC: G01N33/543 ,  G01N33/58

CPC classification number: G01N33/54306 ,  G01N33/582 ,  G01N2458/10 ,  G01N2458/30 ,  G01N2474/00

Abstract: Described herein are methods, systems and kits for conducting an assay for one or more analytes of interest in a sample. In one aspect, a method is provided for conducting a multiplexed binding assay for a plurality of analytes of interest in a sample. In one aspect, the assay includes an analyte binding step and a detection step. In one aspect, the analyte binding step is separated from the detection step.

公开(公告)号：US20240375109A1

公开(公告)日：2024-11-14

申请号：US18597358

申请日：2024-03-06

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Eli N. GLEZER ,  Sudeep KUMAR ,  Pankaj OBEROI ,  George SIGAL ,  Michael TSIONSKY

IPC: B01L3/00 ,  C12Q1/6804 ,  C12Q1/6816 ,  C12Q1/6876 ,  G01N33/543 ,  G01N33/68

Abstract: The invention relates to methods for conducting solid-phase binding assays. Onc example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.