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32 条记录 (耗时 0.024 秒)

    Hemostatic material
    1.
    发明申请
    Hemostatic material 审中-公开
    止血材料

    公开(公告)号：US20070224251A1

    公开(公告)日：2007-09-27

    申请号：US11385750

    申请日：2006-03-22

    申请人： Masao Tanihara ,  Hisao Kinoshita ,  Takayuki Imamura ,  Chikateru Nozaki

    发明人： Masao Tanihara ,  Hisao Kinoshita ,  Takayuki Imamura ,  Chikateru Nozaki

    IPC分类号： A61K38/48 ,  A61L15/00

    CPC分类号： A61K38/4833 ,  A61L15/225 ,  A61L15/32 ,  A61L24/043 ,  A61L24/10 ,  A61L2400/04

    摘要： The present invention provides a hemostatic material which is excellent in hemostatic property, biodegradability and bioabsorbability, uniformity and stability of the quality, as well as reduces a risk of contamination with a pathogenic organism derived from an animal. The hemostatic material comprises a thrombin and a synthetic polypeptide capable of forming a triple helical structure. The polypeptide may show a peak of the molecular weight in the range from 5×104 to 100×104 in the molecular weight distribution. The polypeptide may contain at least a peptide unit represented by the formula: -Pro-X-Gly- (in the formula, X represents Pro or Hyp). The thrombin may be a recombinant. In the hemostatic material, the proportion of the thrombin may be about 0.1 to 500 units (U) relative to 1 mg of the polypeptide. The hemostatic material may further comprise a binder component having biodegradability and bioabsorbability. The hemostatic material may be formed on a substrate.

    摘要翻译： 本发明提供止血性，生物降解性和生物吸收性，质量的均匀性和稳定性优异的止血材料，并且降低了来自动物的病原体的污染的风险。 止血材料包含能够形成三重螺旋结构的凝血酶和合成多肽。 多肽可以在分子量分布中显示分子量在5×10 4至1​​00×10 4范围内的峰。 多肽可以至少含有由下式表示的肽单元：-Pro-X-Gly-（在该式中，X表示Pro或Hyp）。 凝血酶可以是重组体。 在止血材料中，相对于1mg多肽，凝血酶的比例可以为约0.1至500单位（U）。 止血材料还可以包含具有生物降解性和生物吸收性的粘合剂组分。 止血材料可以形成在基底上。

    Genetically modified ecarin and process for producing the same
    3.
    发明申请
    Genetically modified ecarin and process for producing the same 审中-公开
    转基因茄子及其生产方法

    公开(公告)号：US20050164365A1

    公开(公告)日：2005-07-28

    申请号：US10482925

    申请日：2002-07-04

    申请人： Hiroshi Yonemura ,  Takayuki Imamura ,  Hiroshi Nakatake ,  Kenji Soejima ,  Chikateru Nozaki

    发明人： Hiroshi Yonemura ,  Takayuki Imamura ,  Hiroshi Nakatake ,  Kenji Soejima ,  Chikateru Nozaki

    IPC分类号： C12N9/64 ,  C12N15/12 ,  C07H21/04 ,  C12N1/21 ,  C12N5/06 ,  C12N15/74

    CPC分类号： C12N9/6418

    摘要： A recombinant ecarin protein that specifically activates prothrombin, said protein being efficiently prepared by the genetic engineering technique comprising the steps: (1) culturing a transformant microorganism or animal cell transformed with an expression vector in which a gene encoding ecarin is incorporated to the downstream of a promoter so as to produce and accumulate ecarin in culture supernatant or within said transformant and recovering the produced ecarin; and (2) purifying a solution containing the recovered ecarin to obtain purified ecarin. The present invention allows for production of recombinant ecarin on an industrial scale.

    摘要翻译： 一种特异性激活凝血酶原的重组ecarin蛋白，所述蛋白通过遗传工程技术有效地制备，包括以下步骤：（1）培养用表达载体转化的转化体微生物或动物细胞，其中将编码ecarin的基因并入到 促进剂，以在培养上清液或所述转化体内产生和积累ecarin并回收所产生的ecarin; 和（2）纯化含有回收的ecarin的溶液以获得纯化的ecarin。 本发明允许以工业规模生产重组ecarin。

    Output shaft assembly, motor apparatus and wiper motor apparatus
    6.
    发明申请
    Output shaft assembly, motor apparatus and wiper motor apparatus 有权
    输出轴组件，电机装置和刮水器电机装置

    公开(公告)号：US20050097699A1

    公开(公告)日：2005-05-12

    申请号：US10978561

    申请日：2004-11-02

    申请人： Hideyuki Yagi ,  Takayuki Imamura

    发明人： Hideyuki Yagi ,  Takayuki Imamura

    IPC分类号： B60S1/16 ,  F16D7/04 ,  F16D7/02

    CPC分类号： F16D7/044 ,  B60S1/166 ,  Y10T74/18184 ,  Y10T74/19828

    摘要： An input disk, a clutch disk and wave washers are installed to an output shaft to form an output shaft assembly of a motor apparatus. The input disk is axially non-detachable from the output shaft and is rotatable about an axis of the output shaft. The input disk is driven by a drive force supplied from a motor main body of the motor apparatus. The clutch disk is supported by the output shaft in such a manner that the clutch disk is non-rotatable relative to the output shaft and is axially movable along the output shaft relative to the input disk. The wave washers apply a resistive force against axial movement of the clutch disk from a coupled state, at which the input disk is coupled with the clutch disk to rotate together.

    摘要翻译： 输入盘，离合器盘和波形垫圈安装到输出轴上以形成电动机装置的输出轴组件。 输入盘从输出轴轴向不可拆卸并且可绕输出轴的轴线旋转。 输入盘由从马达装置的马达主体提供的驱动力驱动。 离合器盘由输出轴支撑，使得离合器盘相对于输出轴不可旋转，并且可相对于输入盘沿输出轴轴向移动。 波形垫圈施加抵抗离合器盘从耦合状态的轴向移动的阻力，在该状态下，输入盘与离合器盘耦合在一起旋转。

    Motor apparatus and wiper motor apparatus
    7.
    发明授权
    Motor apparatus and wiper motor apparatus 有权
    电动机装置和刮水器电机装置

    公开(公告)号：US07685670B2

    公开(公告)日：2010-03-30

    申请号：US10978561

    申请日：2004-11-02

    申请人： Hideyuki Yagi ,  Takayuki Imamura

    发明人： Hideyuki Yagi ,  Takayuki Imamura

    IPC分类号： F16D7/02

    CPC分类号： F16D7/044 ,  B60S1/166 ,  Y10T74/18184 ,  Y10T74/19828

    摘要： An input disk, a clutch disk and wave washers are installed to an output shaft to form an output shaft assembly of a motor apparatus. The input disk is axially non-detachable from the output shaft and is rotatable about an axis of the output shaft. The input disk is driven by a drive force supplied from a motor main body of the motor apparatus. The clutch disk is supported by the output shaft in such a manner that the clutch disk is non-rotatable relative to the output shaft and is axially movable along the output shaft relative to the input disk. The wave washers apply a resistive force against axial movement of the clutch disk from a coupled state, at which the input disk is coupled with the clutch disk to rotate together.

    摘要翻译： 输入盘，离合器盘和波形垫圈安装到输出轴上以形成电动机装置的输出轴组件。 输入盘从输出轴轴向不可拆卸并且可绕输出轴的轴线旋转。 输入盘由从马达装置的马达主体提供的驱动力驱动。 离合器盘由输出轴支撑，使得离合器盘相对于输出轴不可旋转，并且可相对于输入盘沿输出轴轴向移动。 波形垫圈施加抵抗离合器盘从耦合状态的轴向运动的阻力，在该状态下，输入盘与离合器盘耦合在一起旋转。

    Tissue Sealant
    8.
    发明申请
    Tissue Sealant 审中-公开
    组织密封剂

    公开(公告)号：US20070231372A1

    公开(公告)日：2007-10-04

    申请号：US11597321

    申请日：2005-05-18

    申请人： Takayuki Imamura ,  Noriko Shinya ,  Ryoichi Kawamura ,  Chikateru Nazaki

    发明人： Takayuki Imamura ,  Noriko Shinya ,  Ryoichi Kawamura ,  Chikateru Nazaki

    IPC分类号： A61L24/00

    CPC分类号： A61K38/363 ,  A61K38/4833 ,  A61K45/06 ,  A61L24/0042 ,  A61L24/106

    摘要： The present invention relates to a tissue sealant which is safe and effective. In accordance with the present invention, a tissue sealant comprising as an effective ingredient thrombin and fibrinogen characterized in that a bioabsorbable synthetic nonwoven fabric is used as a supporting material; use of a combination of a bioabsorbable synthetic nonwoven fabric as a supporting material and thrombin and fibrinogen as an effective ingredient for a tissue sealant; use of a combination of a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient, and fibrinogen as an effective ingredient for a tissue sealant; a tissue sealing kit comprising a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient, and a container comprising fibrinogen as an effective ingredient; and a tissue sealing kit comprising a bioabsorbable synthetic nonwoven fabric as a substrate, a container comprising thrombin as an effective ingredient and a container comprising fibrinogen as an effective ingredient are provided.

    摘要翻译： 本发明涉及安全有效的组织密封剂。 根据本发明，包含作为有效成分凝血酶和纤维蛋白原的组织密封剂，其特征在于使用生物可吸收合成无纺布作为支撑材料; 使用生物可吸收合成无纺布作为支撑材料和凝血酶和纤维蛋白原的组合作为组织密封剂的有效成分; 使用保持凝血酶作为有效成分的生物可吸收性合成无纺布和纤维蛋白原作为组织密封剂的有效成分的组合; 包含保持凝血酶作为有效成分的生物可吸收合成无纺布的组织密封试剂盒和包含纤维蛋白原作为有效成分的容器; 提供了包含生物可吸收合成非织造织物作为底物的组织密封套件，包含凝血酶作为有效成分的容器和包含纤维蛋白原作为有效成分的容器。

    Flame resistant polyester from di aryl-di(hydroxyalkylene oxy)aryl phosphine oxide
    9.
    发明授权
    Flame resistant polyester from di aryl-di(hydroxyalkylene oxy)aryl phosphine oxide 失效
    来自二芳基 - 二（羟基亚烷基氧）芳基氧化膦的阻燃聚酯

    公开(公告)号：US5003029A

    公开(公告)日：1991-03-26

    申请号：US534085

    申请日：1990-06-06

    申请人： Atsuko Ueda ,  Tetsuo Matsumoto ,  Takayuki Imamura ,  Keizo Tsujimoto

    发明人： Atsuko Ueda ,  Tetsuo Matsumoto ,  Takayuki Imamura ,  Keizo Tsujimoto

    IPC分类号： C07F9/53 ,  C08G63/19 ,  C08G63/692 ,  C08G65/02 ,  C08G65/32

    CPC分类号： C08G63/6926

    摘要： A flame resistant polyester produced by addition and copolymerization of a phosphorus compound represented by general formula (I) below as a diol component of the polyester in an amount of 500 ppm or more in terms of phosphorus atom content in the polyester, which polyester has alkylene terephthalate units as main repeating units and which has an intrinsic viscosity of not less than 0.5 measured at 20.degree. C. in a mixture of equal weight of phenol and tetrachloroethane: ##STR1## where E is --CH.sub.2 CH.sub.2 --, Ar is an aromatic group or an aromatic group substituted by a lower alkyl group or a halogen atom, and m and n denote, respectively, integers the sum of which is from 1 to 20.

    摘要翻译： 通过下述通式（I）表示的磷化合物的加成和共聚作为聚酯的二醇成分，以聚酯中的磷原子含量计为500ppm以上的聚酯制成的阻燃聚酯，该聚酯具有亚烷基 对苯二甲酸酯单元作为主要重复单元，其特性粘度在20℃下在等体积苯酚和四氯乙烷的混合物中测得的不小于0.5：其中E是-CH 2 CH 2 - ，Ar是 芳基或被低级烷基或卤素原子取代的芳基，m和n分别表示总和为1〜20的整数。