摘要:
The present invention relates to amine derivatives represented by formula (1) or salts thereof. R3 represents C1-C3 alkyl, hydroxylated C1-C5 alkyl, C1-C5 acyl; C2-C5 alkenyl, or a halogen atom; and k, l, and m are each an integer of 1 to 4.) Exhibiting excellent antifungal effect, these compounds are highly useful as antifungal agents, antifungal compositions, drugs, etc.
摘要:
Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. [in the formula (1, R1 represents a C1-5 alkyl group which may be halogenated, R2 represents 4-(1,1-dimethylalkyl)benzyl group, 4-(1-methyl-phenylethyl)benzyl group, 1-or 2-naphthylmethyl group, or a hydrocarbon group having 3,3-dimethyl-1-butynyl group or a phenyl group at its terminal and 1 to 3 double bonds; R3 represents oxygen atom or a methylene group which may be substituted by a C1-4 alkyl group; and R4 represents 1-or 2 naphthyl group or a phenyl group which may be substituted.
摘要翻译:提供了具有下述通式(1)表示的优异的抗真菌作用的新型胺衍生物及其盐。[式1中,R1表示可被卤化的C1-5烷基,R2表示4-(1,1 - 二甲基烷基)苄基,4-(1-甲基 - 苯基乙基)苄基,1-或2-萘基甲基或其末端具有3,3-二甲基-1-丁炔基或苯基的烃基和1 至3个双键; R 3表示氧原子或可被C 1-4烷基取代的亚甲基; R 4表示1或2个萘基或可被取代的苯基。
摘要:
Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor comprises a compound represented by general formula (1) (excluding clotrimazole), and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent, wherein at least one of A1, A2 and A3 is selected from the aryl group and the aromatic heterocyclic group, the total number of carbon atoms contained in A1, A2 and A3 is 6 to 50 and, when at least two of A1, A2 and A3 represent the aryl groups or the aromatic heterocyclic groups, the adjacent two aryl or aromatic heterocyclic groups may be bound to each other via an alkyl chain or an alkenyl chain to form a ring; m represents an integer of 0 to 2; X represents a hetero atom, a hydrogen atom, or a carbon atom; R1 and R2 are independently selected from a hydrogen atom and an oxo group, wherein when one of R1 and R2 is an oxo group, the other is not present; and R3 is selected from a hydrogen atom, and a C1-8 hydrocarbon group in which one or some of hydrogen atoms or carbon atoms may be substituted by a hetero atom or hetero atoms, wherein the number of R3's present in the compound corresponds to the number of X's and, when two or more R3's are present, the R3's are independently present and the adjacent two R3's may be bound to each other to form, together with X, a ring, and the terminal of R3 may be bound to a carbon atom to which A1, A2 and A3 are bound, thereby forming a ring.
摘要:
Disclosed are: a novel skin-whitening agent; and a skin-whitening cosmetic or quasi-drug which is highly effective for prevention/amelioration of melanopathy and is prepared using the skin-whitening agent. The cosmetic contains a compound represented by the general formula (I) and/or a salt thereof as an active ingredient. In the general formula (I), R1 and R2 independently represent a secondary or tertiary alkyl group having 3 to 7 carbon atoms; and R3 represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to carbon atoms.
摘要:
In the electromagnetic switching device, it is possible to miniaturize and have low costs, have quiet operation noise, and also quickly extinguish the arc. The electromagnetic switching device has an electromagnetic actuator with a movable iron core, a pair of fixed terminals that respectively have a fixed contact point, a movable contact that has movable contact points on the right and left ends, a shaft, and an enclosing component that holds the movable contact points and the fixed contact points. The pair of movable contact points respectively contact with and detach from the pair of fixed contact points, and the pair of fixed contact points respectively conduct each other and are insulated again through the shaft by moving the movable iron core along the axis using the electric magnetic actuator. A quasi-hermetically sealed space, which is the extinguishing space, is formed by the enclosing component and a first yoke. A potting compound is charged, into the space between a body and the quasi hermitically sealed space.
摘要:
An open/close control system for an inspection lid adapted not to open while a vehicle travels. The open/close control system has emergency release means which disables power transmission of drive means for opening and closing a side entrance/exit door of a railway vehicle. The emergency release means is installed in a space inside a wall surface inside the vehicle, and the space can be opened and closed by the inspection lid. The emergency release means has locking devices provided in the space inside the wall surface in order to restrict rotation of the inspection lid, and also has an open/close controller for detecting traveling of the railway vehicle to actuate the locking device.
摘要:
A contact structure having a spring with electro conductivity. The spring is fixed at one inner end side of a battery housing by engaging a plurality of inflection parts of the spring to one end side of the battery housing. The spring urges the battery to the other end side of a battery housing. An end portion on movable side end of the spring is extended toward an opening on a lateral face of the battery housing. The end portion is formed on a contact side end of the spring that is contacted with the battery, and is connected to one end side of a bypassing lead wire. An end portion on the fixed side end of the spring is connected to the other end side of the bypassing lead wire. The end portion of the fixed side end of the spring is connected to a power source lead wire. A free end of the contact movable side end can be bent away from the battery to provide a solder connection to the bypass wire.
摘要:
In the electromagnetic switching device, it is possible to miniaturize and have low costs, have quiet operation noise, and also quickly extinguish the arc. The electromagnetic switching device has an electromagnetic actuator with a movable iron core, a pair of fixed terminals that respectively have a fixed contact point, a movable contact that has movable contact points on the right and left ends, a shaft, and an enclosing component that holds the movable contact points and the fixed contact points. The pair of movable contact points respectively contact with and detach from the pair of fixed contact points, and the pair of fixed contact points respectively conduct each other and are insulated again through the shaft by moving the movable iron core along the axis using the electric magnetic actuator. A quasi-hermetically sealed space, which is the extinguishing space, is formed by the enclosing component and a first yoke. A potting compound is charged, into the space between a body and the quasi hermitically sealed space.
摘要:
First and second parallel link mechanisms 36, 38 are connected via a short link 35 arranged on a rotational angle transmission mechanism 29 so that a rotation applied to the first parallel link mechanism 36 is transmitted to the second parallel link mechanism 38 via the rotational angle transmission mechanism 29. The rotational angle transmission mechanism 29, the second parallel link mechanism 38 and the driven side link of the first parallel link mechanism 36 are horizontally supported by the drive side link 30 of the first parallel link mechanism 36. The rotational angle transmission mechanism 29 transmits the rotational angle applied to the drive side link 30 of the first parallel link mechanism 36 to the drive side link 32 of the second parallel link mechanism 38 supported by the drive side link 30 via the guide means that is parallel to the short link 35.
摘要:
A digital camera having a camera body and a lens assembly within an imaging unit which is rotatably connected to the camera body. Rotation of the imaging unit containing the lens assembly with respect to the position of the camera body causes the flash within the camera body to follow the direction at which the lens assembly is aimed. If the camera has a self-portrait mode in which the lens assembly can be aimed backwards at the user of the camera but the flash cannot be aimed backwards due to constraints of the camera body or if the flash cannot cover the complete angular range of the lens, a mechanism is utilized to couple the movement of the lens and the flash over a limited range of movement of the lens. Springs, concentric gears attached by springs, or a clutch mechanism may be utilized to selectively couple the flash with the lens rotation. By separating the flash from the lens, the red-eye phenomena will be reduced.