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131 条记录 (耗时 0.039 秒)

    Guide for localizing a nonpalpable breast lesion
    1.
    发明授权
    Guide for localizing a nonpalpable breast lesion 失效
    本地化不可接受的乳腺炎指南

    公开(公告)号：US5221269A

    公开(公告)日：1993-06-22

    申请号：US597575

    申请日：1990-10-15

    申请人： Richard H. Miller ,  Brian L. Bates ,  Todd A. Hall ,  Thomas A. Osborne

    发明人： Richard H. Miller ,  Brian L. Bates ,  Todd A. Hall ,  Thomas A. Osborne

    IPC分类号： A61M25/01 ,  A61B17/00 ,  A61B19/00 ,  A61F2/00

    CPC分类号： A61B90/39 ,  A61B2017/00349 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61F2210/0019

    摘要： A medical device for localizing a nonpalpable breast lesion. The device includes a tubular introducer needle and a wire guide positioned therein for inserting into a breast to the site of the lesion. The wire guide includes a distal portion having a preformed, resilient helical coil configuration for locking into position about the lesion. The distal portion includes a superelastic metallic alloy for maintaining the helical coil configuration after repeated extensions from and retractions into the needle passageway. The needle is inserted with the wire guide positioned therein into the breast to the site of the lesion and from the distal portion of the needle. The distal end of the needle includes a plurality of indentations for enhancing the ultrasound visualization thereof. As the distal portion of the wire guide emerges from the needle, the acuate distal end of the wire guide cuts into and scribes a helical path about the tissue distal to the lesion. The remainder of the distal portion of the wire guide follows the path scribed by the acuate distal tip and locks about the tissue distal to the lesion. Should the needle and wire guide not be appropriately positioned, the distal portion of the wire guide is retracted into the passageway of the needle to reposition the needle and guide. After desired positioning, the needle is removed with the wire guide remaining in a locked position distally about the lesion for guiding the surgeon to the lesion site during subsequent surgery.

    Coated implantable medical device
    2.
    发明授权
    Coated implantable medical device 有权
    涂层可植入医疗器械

    公开(公告)号：US07901453B2

    公开(公告)日：2011-03-08

    申请号：US11932113

    申请日：2007-10-31

    申请人： Anthony O. Ragheb ,  Neal E. Fearnot ,  William D. Voorhees, III ,  Thomas G. Kozma ,  Brian L. Bates ,  Thomas A. Osborne

    发明人： Anthony O. Ragheb ,  Neal E. Fearnot ,  William D. Voorhees, III ,  Thomas G. Kozma ,  Brian L. Bates ,  Thomas A. Osborne

    IPC分类号： A61F2/06

    CPC分类号： A61K51/1282 ,  A61F2/24 ,  A61F2/82 ,  A61F2250/0068 ,  A61L27/306 ,  A61L27/54 ,  A61L29/085 ,  A61L29/106 ,  A61L29/16 ,  A61L31/088 ,  A61L31/10 ,  A61L31/16 ,  A61L33/022 ,  A61L2300/256 ,  A61L2300/416 ,  A61L2300/602 ,  A61L2300/606 ,  A61L2300/608 ,  A61L2420/08 ,  A61N5/1002 ,  C08L65/04

    摘要： A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract, and at least one layer 18 of an immunosuppressive agent posited over at least one surface of the structure 12. Optionally, the device 10 can include at least one porous, preferably polymeric layer 20 posited over the layer 18 of immunosuppressive agent, and can alternatively or additionally include at least one coating layer 16 posited on one surface of the structure 12, the at least one layer 18 of immunosuppressive agent being posited in turn on at least a portion of the coating layer 16. The porous layer 20 and the coating layer 16 each provide for the controlled release of the bioactive material from the device 10. The structure 12 is preferably configured as a coronary stent. The polymer of the porous layer 20 is preferably applied by vapor or plasma deposition. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative which is deposited without solvents, heat or catalysts, but rather by condensation of a monomer vapor.

    摘要翻译： 涂覆的可植入医疗装置10包括适于引入到血管系统，食管，气管，结肠，胆管或尿道中的结构12，以及至少一个位于结构的至少一个表面上的免疫抑制剂层18 任选地，装置10可以包括位于免疫抑制剂的层18上的至少一个多孔的，优选的聚合物层20，并且可以替代地或另外包括至少一个涂覆层16，该涂层16位于结构12的一个表面上， 至少一层18的免疫抑制剂依次放置在涂层16的至少一部分上。多孔层20和涂层16各自提供生物活性材料从装置10的受控释放。结构12是 优选构造为冠状动脉支架。 多孔层20的聚合物优选通过蒸气或等离子体沉积来施加。 特别优选的是聚合物是聚酰胺，聚对二甲苯或聚对二甲苯衍生物，它们不用溶剂，加热或催化剂沉积，而是通过单体蒸气的冷凝而沉积。

    Medical device for and a method of endoscopic surgery
    8.
    发明授权
    Medical device for and a method of endoscopic surgery 失效
    内镜手术方法及其手术方法

    公开(公告)号：US5112308A

    公开(公告)日：1992-05-12

    申请号：US592676

    申请日：1990-10-03

    申请人： Douglas O. Olsen ,  Brian L. Bates ,  Thomas A. Osborne

    发明人： Douglas O. Olsen ,  Brian L. Bates ,  Thomas A. Osborne

    IPC分类号： A61B1/00 ,  A61B17/22 ,  A61B17/34 ,  A61M25/01 ,  A61M29/00

    CPC分类号： A61B17/3417 ,  A61M29/00

    摘要： A medical device for endoscopic access of a body cavity and a method of percutaneously placing inner and outer access sheaths of the device into the body cavity. The medical device includes inner and outer access sheaths and a dilator which is inserted into the outer sheath and has a shoulder or a shoulder piece for abutting against the proximal end of the outer sheath. The device also includes a wire guide that is percutaneously inserted into the body cavity via an introducer needle. The dilator and outer sheath are placed over the wire guide to dilate the puncture site and introduce the dilator and outer sheath into the body cavity. The dilator comprises an elongated cylindrical member having a passageway opening distally from the conically-shaped distal end and from an outside lateral wall of the dilator about the proximal end. The dilator also includes an end cap which is utilized to force the dilator and the outer sheath through the puncture site and into the body cavity. After positioning in the body cavity, the dilator and wire guide are removed through the outer sheath. The inner sheath is then inserted through the outer sheath into the body cavity. The proximal ends of both the inner and outer sheaths include seals for maintaining insufflation of the body cavity. The inner sheath includes a shoulder piece having a chamber and a side port for connection to an insufflation gas line.