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    SYSTEM FOR OPTICAL BASED DELIVERY OF EXOGENOUS MOLECULES TO CELLS
    1.
    发明申请
    SYSTEM FOR OPTICAL BASED DELIVERY OF EXOGENOUS MOLECULES TO CELLS 审中-公开
    用于基于光源分布的细胞外分泌的系统

    公开(公告)号：US20130052725A1

    公开(公告)日：2013-02-28

    申请号：US13285976

    申请日：2011-10-31

    申请人： Siavash Yazdanfar ,  Vasile Bogdan Neculaes ,  Kenneth Roger Conway ,  Allen Lawrence Garner ,  Evelina Roxana Loghin ,  Dmitry Vladimirovich Dylov ,  Brian Michael Davis ,  Chulmin Joo

    发明人： Siavash Yazdanfar ,  Vasile Bogdan Neculaes ,  Kenneth Roger Conway ,  Allen Lawrence Garner ,  Evelina Roxana Loghin ,  Dmitry Vladimirovich Dylov ,  Brian Michael Davis ,  Chulmin Joo

    IPC分类号： C12M1/42

    CPC分类号： C12M35/02

    摘要： A system for delivering exogenous molecules comprises a support for containing cells and exogenous molecules; an infra-red (IR) light source that generates an IR optical beam with an average power density at least greater than 105 W/cm2; one or more optical elements; an imaging system to image the cells in a field of view; a processor that generates a signal for localization of cells in the field of view; a light pattern shaper for temporal focusing of optical beam to generate wide field illumination on the cells to permeabilise the cell membrane for delivering the exogenous molecules; and a controller that switches optical beam from wide field illumination to a focused illumination. The processor is operatively coupled to the imaging system and the light pattern shaper and transmits the signal for the localization of cells to ensure the temporal focusing of the optical beam on the cells.

    摘要翻译： 用于递送外源分子的系统包括用于含有细胞和外源分子的载体; 红外（IR）光源，其产生平均功率密度至少大于105W / cm2的IR光束; 一个或多个光学元件; 成像系统，用于在视场中对细胞进行成像; 处理器，其在视野中产生用于细胞定位的信号; 用于光束的时间聚焦的光图案整形器以在细胞上产生宽场照明以透过细胞膜以传递外源分子; 以及将光束从宽场照明切换到聚焦照明的控制器。 处理器可操作地耦合到成像系统和光图案整形器，并且传输信号用于细胞的定位，以确保光束在细胞上的时间聚焦。

    METHODS AND SYSTEMS FOR STABILIZATION OF A FLUID USING APPLIED ELECTRICAL FIELDS
    4.
    发明申请
    METHODS AND SYSTEMS FOR STABILIZATION OF A FLUID USING APPLIED ELECTRICAL FIELDS 审中-公开
    使用应用电场稳定流体的方法和系统

    公开(公告)号：US20140017365A1

    公开(公告)日：2014-01-16

    申请号：US13548710

    申请日：2012-07-13

    申请人： Robert Warren Taylor ,  Bradley Stephen Rogers ,  James Easel Roberts ,  Allen Lawrence Garner

    发明人： Robert Warren Taylor ,  Bradley Stephen Rogers ,  James Easel Roberts ,  Allen Lawrence Garner

    IPC分类号： C12H1/02 ,  C25B7/00 ,  B03C5/00

    CPC分类号： B03C3/41 ,  B03C3/366 ,  B03C3/47 ,  B03C2201/08 ,  C12H1/063 ,  C12H1/16 ,  C12M47/02

    摘要： Methods and systems for fluid stabilization are provided. The system includes a first electrical field generator positioned adjacent to a first passage. The first electrical field generator imparts a first electrical field to a fluid flowing through the first passage such that first particles and second particles entrained in the fluid are charged to a first polarity. A first collector positioned within the first passage collects the first particles charged in the fluid. A second electrical field generator positioned adjacent to a second passage is downstream from the first electrical field generator. The second electrical field generator imparts a second electrical field to the fluid discharged from the first passage and substantially neutralizes the second particles entrained in the fluid.

    摘要翻译： 提供了流体稳定的方法和系统。 该系统包括邻近第一通道定位的第一电场发生器。 第一电场发生器向流过第一通道的流体施加第一电场，使得夹带在流体中的第一颗粒和第二颗粒被充电至第一极性。 位于第一通道内的第一收集器收集流入流体中的第一颗粒。 位于第二通道附近的第二电场发生器位于第一电场发生器的下游。 第二电场发生器向从第一通道排出的流体施加第二电场，并基本上中和夹带在流体中的第二颗粒。

    RADIOISOTOPE POWER SOURCE
    5.
    发明申请
    RADIOISOTOPE POWER SOURCE 失效
    放射源电源

    公开(公告)号：US20110100439A1

    公开(公告)日：2011-05-05

    申请号：US12608589

    申请日：2009-10-29

    申请人： Brent Allen Clothier ,  Matthew Christian Nielsen ,  Todd Ryan Tolliver ,  Allen Lawrence Garner

    发明人： Brent Allen Clothier ,  Matthew Christian Nielsen ,  Todd Ryan Tolliver ,  Allen Lawrence Garner

    IPC分类号： H01L31/02 ,  G21C21/02

    CPC分类号： H01L31/055 ,  G21H1/12 ,  H01L31/115 ,  H02N11/008 ,  Y02E10/52

    摘要： A radioisotope power sources that includes radioisotope nanoparticles and scintillator materials. An embodiment of the radioisotope power source includes radioisotope nanoparticles suspended within a polycrystalline scintillator; additional polycrystalline scintillator at least partially surrounding the polycrystalline scintillator with the radioisotope nanoparticles; and a photovoltaic device in light communication with the surrounding polycrystalline scintillator. A system that employs the radioisotope power source and a method of generating an electrical current are also disclosed. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appending claims.

    摘要翻译： 包括放射性同位素纳米颗粒和闪烁体材料的放射性同位素电源。 放射性同位素电源的实施例包括悬浮在多晶闪烁器内的放射性同位素纳米粒子; 另外的多晶闪烁体至少部分地围绕着具有放射性同位素纳米颗粒的多晶闪烁体; 以及与周围的多晶闪烁体光连通的光电器件。 还公开了采用放射性同位素电源的系统和产生电流的方法。 已经根据具体实施例描述了本发明，并且认识到除了明确说明的那些之外的等同物，替代方案和修改是可能的并且在所附权利要求的范围内。

    Radioisotope power source
    6.
    发明授权
    Radioisotope power source 失效
    放射性同位素电源

    公开(公告)号：US08294023B2

    公开(公告)日：2012-10-23

    申请号：US12608589

    申请日：2009-10-29

    申请人： Brent Allen Clothier ,  Matthew Christian Nielsen ,  Todd Ryan Tolliver ,  Allen Lawrence Garner

    发明人： Brent Allen Clothier ,  Matthew Christian Nielsen ,  Todd Ryan Tolliver ,  Allen Lawrence Garner

    IPC分类号： H01L31/00 ,  H01M14/00 ,  G21H1/00 ,  C09K11/54 ,  C09K11/72

    CPC分类号： H01L31/055 ,  G21H1/12 ,  H01L31/115 ,  H02N11/008 ,  Y02E10/52

    摘要： A radioisotope power sources that includes radioisotope nanoparticles and scintillator materials. An embodiment of the radioisotope power source includes radioisotope nanoparticles suspended within a polycrystalline scintillator; additional polycrystalline scintillator at least partially surrounding the polycrystalline scintillator with the radioisotope nanoparticles; and a photovoltaic device in light communication with the surrounding polycrystalline scintillator. A system that employs the radioisotope power source and a method of generating an electrical current are also disclosed. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appending claims.

    摘要翻译： 包括放射性同位素纳米颗粒和闪烁体材料的放射性同位素电源。 放射性同位素电源的实施例包括悬浮在多晶闪烁器内的放射性同位素纳米粒子; 另外的多晶闪烁体至少部分地围绕着具有放射性同位素纳米颗粒的多晶闪烁体; 以及与周围的多晶闪烁体光连通的光电器件。 还公开了采用放射性同位素电源的系统和产生电流的方法。 已经根据具体实施例描述了本发明，并且认识到除了明确说明的那些之外的等同物，替代方案和修改是可能的并且在所附权利要求的范围内。