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1.发明申请APPARATUS FOR PERFORMING SPECTROSCOPY HAVING A PARABOLIC REFLECTOR AND SERS ELEMENTS 审中-公开用于执行具有抛物面反射器和元件元件的光谱的装置公开(公告)号：US20150241355A1
公开(公告)日：2015-08-27
申请号：US14406653
申请日：2012-07-31
Applicant: Shih-Yuan Wang , Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Steven Barcelo , Ansoon Kim , Mineo Yamakawa , Zhang-Lin Zhou , Huei Pei Kuo
Inventor： Shih-Yuan Wang , Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Steven Barcelo , Ansoon Kim , Mineo Yamakawa , Zhang-Lin Zhou , Huei Pei Kuo
CPC classification number: G01N21/658 , A61F2/02 , A61F2/82 , G01N2201/068 , G02B5/10 , Y10T29/49826
Abstract: According to an example, an apparatus for performing spectroscopy includes a parabolic reflector and a plurality of surface-enhanced Raman spectroscopy (SERS) elements spaced from the parabolic reflector and positioned substantially at a focal point of the parabolic reflector. The parabolic reflector is to reflect Raman scattered light emitted from molecules in a near field generated by the plurality of SERS elements to substantially increase the flux of the Raman scattered light emitted out of the apparatus.
Abstract translation: 根据一个实例，用于执行光谱学的装置包括抛物面反射器和与抛物面反射器间隔开并且基本上位于抛物面反射器的焦点的多个表面增强拉曼光谱（SERS）元件。 抛物面反射器是反射由多个SERS元件产生的近场中的分子发射的拉曼散射光，以大大增加从该装置发出的拉曼散射光的通量。
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公开(公告)号：US20150103340A1
公开(公告)日：2015-04-16
申请号：US14405334
申请日：2012-07-29
Applicant: Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Shih-Yuan Wang , Huei Pei Kuo , Steven Barcelo , Zhang-Lin Zhou
Inventor： Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Shih-Yuan Wang , Huei Pei Kuo , Steven Barcelo , Zhang-Lin Zhou
IPC: G01N21/65
CPC classification number: G01N21/658 , B82Y15/00 , G01J3/4412 , G01N2021/651 , G01N2201/06113 , Y10S977/902
Abstract: A scattering spectroscopy nanosensor includes a nanoscale-patterned sensing substrate to produce an optical scattering response signal indicative of a presence of an analyte when interrogated by an optical stimulus. The scattering spectroscopy nanosensor further includes a protective covering to cover and protect the nanoscale-patterned sensing substrate. The protective covering is to be selectably removed by exposure to an optical beam incident on the protective covering. The protective covering is to prevent the analyte from interacting with the nanoscale-patterned sensing substrate prior to being removed.
Abstract translation: 散射光谱纳米传感器包括纳米级图案化的感测衬底，以产生指示当通过光学刺激询问的分析物存在时的光学散射响应信号。 散射光谱纳米传感器还包括覆盖并保护纳米级图案化感测基板的保护覆盖层。 通过暴露在入射到保护罩上的光束可选地去除保护罩。 保护性覆盖物是在去除之前防止分析物与纳米级图案化的感测基板相互作用。
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公开(公告)号：US09212997B2
公开(公告)日：2015-12-15
申请号：US14405334
申请日：2012-07-29
Applicant: Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Shih-Yuan Wang , Huei Pei Kuo , Steven Barcelo , Zhang-Lin Zhou
Inventor： Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Shih-Yuan Wang , Huei Pei Kuo , Steven Barcelo , Zhang-Lin Zhou
CPC classification number: G01N21/658 , B82Y15/00 , G01J3/4412 , G01N2021/651 , G01N2201/06113 , Y10S977/902
Abstract: A scattering spectroscopy nanosensor includes a nanoscale-patterned sensing substrate to produce an optical scattering response signal indicative of a presence of an analyte when interrogated by an optical stimulus. The scattering spectroscopy nanosensor further includes a protective covering to cover and protect the nanoscale-patterned sensing substrate. The protective covering is to be selectably removed by exposure to an optical beam incident on the protective covering. The protective covering is to prevent the analyte from interacting with the nanoscale-patterned sensing substrate prior to being removed.
Abstract translation: 散射光谱纳米传感器包括纳米级图案化的感测衬底，以产生指示当通过光学刺激询问的分析物存在时的光学散射响应信号。 散射光谱纳米传感器还包括覆盖并保护纳米级图案化感测基板的保护覆盖层。 通过暴露在入射到保护罩上的光束可选地去除保护罩。 保护性覆盖物是在去除之前防止分析物与纳米级图案化的感测基板相互作用。
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4.发明申请IMMOBILIZING CHEMICAL OR BIOLOGICAL SENSING MOLECULES ON SEMI-CONDUCTING NANOWIRES 有权半导体纳米粒子化学或生物传感分子的固定化公开(公告)号：US20110269240A1
公开(公告)日：2011-11-03
申请号：US10795730
申请日：2004-03-08
Applicant: Zhang-Lin Zhou , Zhiyong Li , Sean Xiao-An Zhang
Inventor： Zhang-Lin Zhou , Zhiyong Li , Sean Xiao-An Zhang
CPC classification number: G01N33/54373 , B82Y15/00 , B82Y30/00 , Y10S977/70 , Y10S977/742 , Y10S977/745 , Y10S977/842
Abstract: The present invention is drawn toward a chemical or biological sensor that can comprise a semi-conducting nanowire and a chemical or biological sensing molecule tethered to the semi-conducting nanowire through a spacer group including a hydrophilic reactive group. In one embodiment, the semi-conducting nanowire can be part of an array of like or similar semi-conducting nanowires. Electrical leads can provide an electrical current to the array, and a signal measurement apparatus can be electrically coupled to the array, and can be configured for detecting changes in the electrical current of the array.
Abstract translation: 本发明涉及化学或生物传感器，其可以包括通过包括亲水反应性基团的间隔基团连接到半导体纳米线的半导体纳米线和化学或生物传感分子。 在一个实施例中，半导体纳米线可以是类似或类似的半导体纳米线阵列的一部分。 电引线可以向阵列提供电流，并且信号测量装置可以电耦合到阵列，并且可以被配置为检测阵列的电流的变化。
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5.发明授权Reconfigurable molecules and molecular switches, sensors, and dyes employing the same 失效可重构分子和分子开关，传感器和使用它们的染料公开(公告)号：US08044212B2
公开(公告)日：2011-10-25
申请号：US11799147
申请日：2007-04-30
Applicant: Zhang-Lin Zhou , Zhiyong Li
Inventor： Zhang-Lin Zhou , Zhiyong Li
IPC: C07D235/02
CPC classification number: H01L51/008 , B82Y10/00 , C07D207/46 , G11C2213/14 , H01L51/0072 , H01L51/0595
Abstract: Various embodiment of the present invention are directed to organic molecules that are reconfigurable under application of an external electric field. One organic molecule embodiment of the present invention has the structure: where L1X1 and L2X2 are optional connector groups, A represents an electron acceptor group, D represents an electron donor group, R and R′ represent spacer molecules, and R1, R2, R3, R4, R5, R6, R7, and R8 represent atoms and hydrocarbons.
Abstract translation: 本发明的各种实施方案涉及在外部电场的应用下可重新配置的有机分子。 本发明的一个有机分子实施方案具有以下结构：其中L1X1和L2X2是任选的连接基团，A代表电子受体基团，D代表电子给体基团，R和R'代表间隔基分子，R1，R2，R3， R4，R5，R6，R7和R8表示原子和烃。
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Patent Agency Ranking
6.发明申请Reconfigurable molecules and molecular switches, sensors, and dyes employing the same 失效可重构分子和分子开关，传感器和使用它们的染料公开(公告)号：US20080269486A1
公开(公告)日：2008-10-30
申请号：US11799147
申请日：2007-04-30
Applicant: Zhang-Lin Zhou , Zhiyong Li
Inventor： Zhang-Lin Zhou , Zhiyong Li
IPC: C07D239/00 , H01L29/00
CPC classification number: H01L51/008 , B82Y10/00 , C07D207/46 , G11C2213/14 , H01L51/0072 , H01L51/0595
Abstract: Various embodiment of the present invention are directed to organic molecules that are reconfigurable under application of an external electric field. One organic molecule embodiment of the present invention has the structure: where L1X1 and L2X2 are optional connector groups, A represents an electron acceptor group, D represents an electron donor group, R and R′ represent spacer molecules, and R1, R2, R3, R4, R5, R6, R7, and R8 represent atoms and hydrocarbons.
Abstract translation: 本发明的各种实施方案涉及在外部电场的应用下可重新配置的有机分子。 本发明的一个有机分子实施方案具有以下结构：其中L 1 X 1和X 2 X 2 X 2 是可选的连接基团，A表示电子受体基团，D表示电子给体基团，R和R'表示间隔基分子，R 1，R 2， R 3，R 4，R 5，R 6，R 7和R 7， 8 表示原子和烃。
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7.发明申请公开(公告)号：US20060180480A1
公开(公告)日：2006-08-17
申请号：US11059258
申请日：2005-02-15
Applicant: Sean Zhang , Zhiyong Li , Zhang-Lin Zhou , William Tong , R. Williams , Yong Chen
Inventor： Sean Zhang , Zhiyong Li , Zhang-Lin Zhou , William Tong , R. Williams , Yong Chen
IPC: G01F1/64 , G01N33/487 , G01N27/26
CPC classification number: G01N33/5308 , G01N33/5438 , G01N2430/00
Abstract: A sensor array for sensing at least one of chemical moieties and biological moieties is provided. The sensor array comprises a plurality of working electrodes electrically associated with a reference electrode, each working electrode in combination with the reference electrode forming a transducer. Each working electrode is provided with a coating of a sensing element comprised of an ionizable moiety and a functional group sensitive to one of the chemical and/or biological moieties.
Abstract translation: 提供了用于感测化学部分和生物部分中的至少一个的传感器阵列。 传感器阵列包括与参考电极电连接的多个工作电极，每个工作电极与参考电极组合形成换能器。 每个工作电极设置有由可电离部分和对化学和/或生物部分之一敏感的官能团组成的感测元件的涂层。
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公开(公告)号：US09019495B2
公开(公告)日：2015-04-28
申请号：US13563362
申请日：2012-07-31
Applicant: Ansoon Kim , Zhiyong Li , Steven J. Barcelo , Zhang-Lin Zhou , Gary Gibson
Inventor： Ansoon Kim , Zhiyong Li , Steven J. Barcelo , Zhang-Lin Zhou , Gary Gibson
CPC classification number: G01N21/658 , G01N2021/775 , Y10T29/49826
Abstract: According to an example, an apparatus for performing spectroscopy includes a structure having an opening. The apparatus also includes a plurality of surface-enhanced Raman spectroscopy (SERS) elements positioned within the structure and a porous membrane covering the opening and the plurality of SERS elements. The porous membrane is to allow a predetermined analyte to reach the SERS elements while substantially preventing other analytes from reaching the SERS elements.
Abstract translation: 根据示例，用于执行光谱的装置包括具有开口的结构。 该装置还包括位于结构内的多个表面增强拉曼光谱（SERS）元件和覆盖该开口的多孔膜和多个SERS元件。 多孔膜是允许预定的分析物到达SERS元素，同时基本上防止其它分析物到达SERS元件。
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公开(公告)号：US20140036263A1
公开(公告)日：2014-02-06
申请号：US13563362
申请日：2012-07-31
Applicant: Ansoon KIM , Zhiyong Li , Steven J. Barcelo , Zhang-Lin Zhou , Gary Gibson
Inventor： Ansoon KIM , Zhiyong Li , Steven J. Barcelo , Zhang-Lin Zhou , Gary Gibson
CPC classification number: G01N21/658 , G01N2021/775 , Y10T29/49826
Abstract: According to an example, an apparatus for performing spectroscopy includes a structure having an opening. The apparatus also includes a plurality of surface-enhanced Raman spectroscopy (SERS) elements positioned within the structure and a porous membrane covering the opening and the plurality of SERS elements. The porous membrane is to allow a predetermined analyte to reach the SERS elements while substantially preventing other analytes from reaching the SERS elements.
Abstract translation: 根据示例，用于执行光谱的装置包括具有开口的结构。 该装置还包括位于结构内的多个表面增强拉曼光谱（SERS）元件和覆盖该开口的多孔膜和多个SERS元件。 多孔膜是允许预定的分析物到达SERS元素，同时基本上防止其它分析物到达SERS元件。
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10.发明申请ELECTRONIC AND PLASMONIC ENHANCEMENT FOR SURFACE ENHANCED RAMAN SPECTROSCOPY 审中-公开表面增强拉曼光谱的电子和等离子体增强公开(公告)号：US20140036262A1
公开(公告)日：2014-02-06
申请号：US13562567
申请日：2012-07-31
Applicant: Shih-Yuan Wang , Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Huei Pei Kuo , Zhang-Lin Zhou , R Stanley Williams
Inventor： Shih-Yuan Wang , Gary Gibson , Zhiyong Li , Alexandre M. Bratkovski , Huei Pei Kuo , Zhang-Lin Zhou , R Stanley Williams
IPC: G01J3/44
CPC classification number: G01N21/658
Abstract: An apparatus for surface enhanced Raman spectroscopy includes a substrate, a nanostructure and a plasmonic material. The nanostructure and the plasmonic material are integrated together to provide electronic and plasmonic enhancement to a Raman signal produced by electromagnetic radiation scattering from an analyte.
Abstract translation: 用于表面增强拉曼光谱的装置包括底物，纳米结构和等离子体激元材料。 将纳米结构和等离子体激元材料集成在一起，以对由分析物的电磁辐射散射产生的拉曼信号提供电子和等离子体增强。
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