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公开(公告)号:US10017650B2
公开(公告)日:2018-07-10
申请号:US15142333
申请日:2016-04-29
Applicant: AMERICAN STERILIZER COMPANY
Inventor: Herbert J. Kaiser , Miranda C. Shaver , Timothy Lee Giddens
Abstract: Reactive compositions are provided, having biocidal and chemical decontamination/neutralization properties, comprising a hygroscopic polymer and an active, which are useful in a variety of commercial, healthcare and military applications and a wide variety of contaminants, including without limitation chemical and biological warfare agents. The reactive compositions are renewable or rechargeable after use by exposure to an additional application of the active and do not require removal, disposal or replacement of the originally applied composition. Methods for preparing and applying the reactive compositions are disclosed.
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公开(公告)号:US20180124892A1
公开(公告)日:2018-05-03
申请号:US15642379
申请日:2017-07-06
Applicant: American Sterilizer Company
Inventor: Michael Hollopeter , David Jesurun
CPC classification number: H05B33/0854 , A61B90/30 , A61B2090/309 , H05B33/0842
Abstract: An adaptive shadow control system that compensates for blockage of one lighthead of a surgical lighting system by increasing the light output from one or more other lightheads of the lighting system. The system also includes control logic for automatic enablement/disablement of adaptive shadow control by detecting whether there is blockage of a lighthead and whether the respective light beams of a plurality of lightheads are being aggregated to form a single aggregated co-illumination light pattern at a work area.
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公开(公告)号:US20180103637A1
公开(公告)日:2018-04-19
申请号:US15296163
申请日:2016-10-18
Applicant: American Sterilizer Company
Inventor: Phillip P. FRANCISKOVICH , Kathleen A. FIX , Donald G. ROSENHAMER
Abstract: A sterilant composition is disclosed which contains peracetic acid and a non-aqueous solvent. The sterilant composition may include one or more of a buffer, an anticorrosive agent and a chelator. The sterilant composition may be free of added water. The sterilant composition may be used for sterilizing articles such as medical, dental, pharmaceutical, veterinary or mortuary instruments, devices, and the like.
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公开(公告)号:US20170275632A1
公开(公告)日:2017-09-28
申请号:US15618157
申请日:2017-06-09
Applicant: American Sterilizer Company
Inventor: Phillip P. Franciskovich , Tricia A. Cregger , William A. Yirava , Peter A. Burke
CPC classification number: C12N15/75 , A61L2/28 , C12M1/34 , C12M37/06 , C12N9/2471 , C12Q1/22 , C12Q1/34 , C12Q1/689 , C12Q1/6897 , C12Y302/01023
Abstract: This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
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公开(公告)号:US20170275631A1
公开(公告)日:2017-09-28
申请号:US15618156
申请日:2017-06-09
Applicant: American Sterilizer Company
Inventor: Phillip P. Franciskovich , Tricia A. Cregger , William A. Yirava , Peter A. Burke
CPC classification number: C12N15/75 , A61L2/28 , C12M1/34 , C12M37/06 , C12N9/2471 , C12Q1/22 , C12Q1/34 , C12Q1/689 , C12Q1/6897 , C12Y302/01023
Abstract: This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
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公开(公告)号:US09701968B2
公开(公告)日:2017-07-11
申请号:US15204124
申请日:2016-07-07
Applicant: American Sterilizer Company
Inventor: Phillip P. Franciskovich , Tricia A. Cregger , William A. Yirava , Peter A. Burke
CPC classification number: C12N15/75 , A61L2/28 , C12M1/34 , C12M37/06 , C12N9/2471 , C12Q1/22 , C12Q1/34 , C12Q1/689 , C12Q1/6897 , C12Y302/01023
Abstract: This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
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97.
公开(公告)号:US20170138669A1
公开(公告)日:2017-05-18
申请号:US14940231
申请日:2015-11-13
Applicant: American Sterilizer Company
Inventor: Michael Bacik , Shadruz Daraie , Peter J. Buczynski
IPC: F28C3/04
CPC classification number: F28C3/04 , A61L2/07 , A61L2/26 , A61L2202/122 , A61L2202/13
Abstract: This invention relates to a process for reducing the temperature of an effluent stream flowing out of a sterilization chamber. The process involves the use of a mixing tank and heat exchangers which provide for cooling the effluent to a temperature required by local drain or sewer requirements (e.g., below about 60° C.) while saving on the amount of cooling water needed to cool the effluent.
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公开(公告)号:US20160312263A1
公开(公告)日:2016-10-27
申请号:US15204124
申请日:2016-07-07
Applicant: American Sterilizer Company
Inventor: Phillip P. Franciskovich , Tricia A. Cregger , William A. Yirava , Peter A. Burke
CPC classification number: C12N15/75 , A61L2/28 , C12M1/34 , C12M37/06 , C12N9/2471 , C12Q1/22 , C12Q1/34 , C12Q1/689 , C12Q1/6897 , C12Y302/01023
Abstract: This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
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公开(公告)号:US20160102335A1
公开(公告)日:2016-04-14
申请号:US14512708
申请日:2014-10-13
Applicant: AMERICAN STERILIZER COMPANY
Inventor: Phillip P. Franciskovich , Tricia A. Cregger , William A. Yirava , Peter A. Burke
CPC classification number: C12N15/75 , A61L2/28 , C12M1/34 , C12M37/06 , C12N9/2471 , C12Q1/22 , C12Q1/34 , C12Q1/689 , C12Q1/6897 , C12Y302/01023
Abstract: This invention relates to a biological indicator derived from a composition comprising: a host organism comprising a spore forming bacteria; a reporter gene for producing an indicator enzyme; a regulatory gene; and a vehicle for inserting the reporter gene and the regulatory gene in the host organism; the host organism bearing a transposable genetic element in its genome for inserting an insertion sequence in the regulatory gene; the insertion sequence comprising a transposase, a pair of terminal inverted repeat sequences, and at least one open reading frame for expressing the transposase. The vehicle may be taken up by the host organism. The insertion sequence may be inserted in the regulatory gene. The host organism may undergo sporulation to form the biological indicator. A process and an apparatus for using the biological indicator are disclosed.
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100.
公开(公告)号:US09303283B2
公开(公告)日:2016-04-05
申请号:US14090116
申请日:2013-11-26
Applicant: American Sterilizer Company
Inventor: Phillip P. Franciskovich , Tricia A. Cregger , Paul Vodkin
Abstract: A combined sterilization indicator incubator and reader system, including a sterilization indicator vial containing one of a variety of selected biological indicators and a liquid, at least two incubator blocks, each incubator block independently operable to incubate the sterilization indicator vial at a plurality of independently selectable temperatures, each of the incubator blocks including at least one heating element operable to heat the incubator block to any one of the plurality of independently selectable temperatures; a light source, a photodetector and a control system configured to operate the combined system to determine the efficacy of a variety of sterilization processes. The system calculates and compares a slope to a predetermined threshold slope for the biological indicator, and provides output based only on the comparison of the calculated slope to the predetermined threshold slope without first determining either a baseline or a minimum value of the output from the photodetector.
Abstract translation: 一种组合的灭菌指示器培养箱和读取器系统,包括含有多种选择的生物指示剂中的一种的灭菌指示剂小瓶和液体的至少两个培养箱块,每个培养箱块可独立操作以将灭菌指示剂小瓶以多个可独立选择的温度 每个孵化器块包括至少一个加热元件,其可操作以将培养箱块加热到多个可独立选择的温度中的任何一个; 光源,光电检测器和控制系统,其被配置为操作组合系统以确定各种灭菌过程的功效。 该系统计算并比较生物学指示器的斜率与预定阈值斜率,并且仅基于所计算的斜率与预定阈值斜率的比较来提供输出,而不首先确定来自光电探测器的输出的基线或最小值 。
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