公开(公告)号：US20050249763A1

公开(公告)日：2005-11-10

申请号：US11105528

申请日：2005-04-14

Applicant: Jean-Yves Legendre ,  Carole Guiramand ,  Guillaume Cassin ,  Jean-Thierry Simonnet

Inventor： Jean-Yves Legendre ,  Carole Guiramand ,  Guillaume Cassin ,  Jean-Thierry Simonnet

IPC: A61K8/02 ,  A61Q19/00 ,  A61Q19/08 ,  A61K7/32

CPC classification number: A61Q19/008 ,  A61K8/0208 ,  A61K2800/88 ,  A61Q19/00 ,  A61Q19/08

Abstract: The present invention relates to kits for formulating a cosmetic product, containing an aqueous composition and at least one water-soluble anhydrous film, the aqueous composition and the film(s) being mixed together extemporaneously to form the cosmetic product.

Abstract translation: 本发明涉及用于配制化妆品的试剂盒，其含有水性组合物和至少一种水溶性无水膜，所述水性组合物和所述膜同时混合在一起以形成所述化妆品。

公开(公告)号：US20050175651A1

公开(公告)日：2005-08-11

申请号：US11027993

申请日：2005-01-04

Applicant: Jean-Thierry Simonnet ,  Pascal Richart ,  Bruno Biatry

Inventor： Jean-Thierry Simonnet ,  Pascal Richart ,  Bruno Biatry

IPC: A61K9/51 ,  A61K7/135 ,  A61K9/16 ,  A61K9/50

CPC classification number: A61K9/5146 ,  A61K9/5161 ,  A61K9/5192

Abstract: The present invention relates to an aqueous dispersion of nanocapsules of core/shell type, in which: the core comprises at least one oil, the shell covering the core is of non-crosslinked polymeric nature and is water-insoluble and insoluble in the oil of the said core, the said nanocapsules having a mean size of less than or equal to 1 μm and having a degree of encapsulation of at least 8% by weight relative to the total weight of the said dispersion.

Abstract translation: 本发明涉及核/壳型纳米胶囊的水性分散体，其中：芯包含至少一种油，覆盖芯的壳具有非交联的聚合性质，并且是不溶于水且不溶于油的 所述芯，所述纳米胶囊具有小于或等于1μm的平均尺寸，并且相对于所述分散体的总重量具有至少8重量％的包封程度。

公开(公告)号：US20050031699A1

公开(公告)日：2005-02-10

申请号：US10876527

申请日：2004-06-28

Applicant: Jean-Thierry Simonnet ,  Bruno Biatry ,  Didier Saint-Leger

Inventor： Jean-Thierry Simonnet ,  Bruno Biatry ,  Didier Saint-Leger

IPC: A61K8/04 ,  A61K8/25 ,  A61K8/88 ,  A61K9/14 ,  A61Q5/00 ,  A61Q19/00

CPC classification number: A61K8/88 ,  A61K8/0279 ,  A61K8/25 ,  A61K2800/412 ,  A61K2800/56 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q19/00

Abstract: The present invention relates to individualized porous particles, characterized in that they have a volume-average diameter of less than or equal to 10 μm and a specific surface area of greater than or equal to 1 m2/g, and in that they comprise at least one cosmetically or pharmaceutically active compound at least present inside said particles.

Abstract translation: 本发明涉及个体化多孔颗粒，其特征在于它们具有小于或等于10μm的体积平均直径和大于或等于1m 2 / g的比表面积，并且因为它们 包含至少一种至少存在于所述颗粒内的美容或药学活性化合物。

公开(公告)号：US06464990B2

公开(公告)日：2002-10-15

申请号：US09477715

申请日：2000-01-05

Applicant: Jean-Thierry Simonnet ,  Odile Sonneville ,  Sylvie Legret

Inventor： Jean-Thierry Simonnet ,  Odile Sonneville ,  Sylvie Legret

IPC: A61K600

CPC classification number: B82Y5/00 ,  A61K8/062 ,  A61K8/90 ,  A61K9/0048 ,  A61K9/1075 ,  A61K31/77 ,  A61K2800/21 ,  A61K2800/413 ,  A61Q1/14 ,  B01F17/0028 ,  Y10S514/873 ,  Y10S514/937 ,  Y10S514/938

Abstract: A nanoemulsion comprising an oily phase dispersed in an aqueous phase and having oil globules with a number-average size of less than 100 mm, which dispersion is facilitated by a surfactant comprised of polyethylene oxide and polypropylene oxide blocks, the oily phase comprising at least one oil having a molecular weight of greater than 400 and wherein the ratio by weight of the amount of oily phase to the amount of surfactant ranges from 2 to 10.

Abstract translation: 一种纳米乳液，其包含分散在水相中的油相，并且具有小于100mm的数均粒径的油球，所述分散体由包含聚环氧乙烷和聚环氧丙烷嵌段的表面活性剂促进，所述油相包含至少一种 分子量大于400的油，其中油相量与表面活性剂的重量比为2至10。

公开(公告)号：US6120778A

公开(公告)日：2000-09-19

申请号：US772724

申请日：1996-12-23

Applicant: Jean-Thierry Simonnet

Inventor： Jean-Thierry Simonnet

IPC: A61K8/55 ,  A61K8/06 ,  A61K8/34 ,  A61K8/46 ,  A61K8/58 ,  A61K8/63 ,  A61K8/72 ,  A61K8/89 ,  A61K8/891 ,  A61K8/92 ,  A61K9/107 ,  A61K47/34 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q19/00 ,  B01F17/54 ,  C08L83/12 ,  A61K7/00

CPC classification number: B82Y5/00 ,  A61K8/062 ,  A61K8/585 ,  A61K9/1075 ,  A61Q19/00 ,  A61K2800/21 ,  A61K2800/262 ,  A61K2800/413 ,  A61K47/34 ,  A61Q19/005 ,  A61Q19/008 ,  Y10S514/938

Abstract: The present application relates to a transparent oil-in-water emulsion, the oil globules of which have a mean size of less than 100 nm, which comprises at least one silicone surfactant. The emulsion according to the invention is stable on storage and can contain significant amounts of oil while retaining good transparency. It can contain heat-sensitive active principles and can be used in particular in the cosmetics field and in dermatology for the treatment and the care of the skin, mucous membranes, nails, scalp and hair.

Abstract translation: 本申请涉及一种透明的水包油乳液，其油球的平均尺寸小于100nm，其包含至少一种硅氧烷表面活性剂。 根据本发明的乳液在储存时稳定，并且可以含有大量的油，同时保持良好的透明度。 它可以含有热敏性活性成分，特别可用于化妆品领域和皮肤科用于治疗和护理皮肤，粘膜，指甲，头皮和头发。

公开(公告)号：US5919487A

公开(公告)日：1999-07-06

申请号：US771837

申请日：1996-12-23

Applicant: Jean-Thierry Simonnet ,  Pascal Richart

Inventor： Jean-Thierry Simonnet ,  Pascal Richart

IPC: A61K8/55 ,  A61K8/02 ,  A61K8/04 ,  A61K8/11 ,  A61K8/14 ,  A61K8/58 ,  A61K8/63 ,  A61K8/64 ,  A61K8/67 ,  A61K8/72 ,  A61K8/81 ,  A61K8/89 ,  A61K8/894 ,  A61K8/898 ,  A61Q19/00 ,  A61Q19/08 ,  B01J13/22 ,  C08L83/12 ,  A61K9/16 ,  A61K9/50

CPC classification number: A61K8/894 ,  A61K8/11 ,  A61K8/671 ,  A61K8/678 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q3/00 ,  A61Q5/00 ,  B01J13/22 ,  B82Y5/00 ,  A61K2800/412

Abstract: The present invention relates to nanoparticles, and in particular nanocapsules, provided with a lamellar coating obtained from a silicone surfactant, and to their use in a composition, in particular a topical composition, for treatment of the skin, mucosae, nails, scalp and/or hair.

Abstract translation: 本发明涉及具有由硅氧烷表面活性剂获得的层状涂层的纳米颗粒，特别是纳米胶囊，以及它们在组合物，特别是局部组合物中的用途，用于治疗皮肤，粘膜，指甲，头皮和/ 或头发。

公开(公告)号：US5866158A

公开(公告)日：1999-02-02

申请号：US736936

申请日：1996-10-28

Applicant: Alain Ribier ,  Jean-Thierry Simonnet ,  Rose-Marie Handjani ,  Nadia Terren

Inventor： Alain Ribier ,  Jean-Thierry Simonnet ,  Rose-Marie Handjani ,  Nadia Terren

IPC: A61K8/14 ,  A61K8/39 ,  A61K8/49 ,  A61K8/60 ,  A61K8/70 ,  A61K8/86 ,  A61Q1/02 ,  A61Q19/00 ,  A61Q19/08 ,  A61K9/127 ,  A61K7/00

CPC classification number: A61Q19/08 ,  A61K8/14 ,  A61K8/39 ,  A61K8/4973 ,  A61K8/4993 ,  A61K8/60 ,  A61K8/70 ,  A61K8/86 ,  A61Q19/00 ,  B82Y5/00 ,  A61Q1/02 ,  A61Q19/007 ,  Y10T428/2984

Abstract: The vesicles are prepared from a lipid phase containing a mixture of nonionic amphiphilic lipids consisting of a mixture of esters of at least one polyol chosen from the group composed of polyethylene glycol containing from 1 to 60 ethylene oxide units, sorbitan, sorbitan bearing 2 to 60 ethylene oxide units, glycerol bearing 2 to 30 ethylene oxide units, polyglycerols containing 2 to 15 glycerol units, sucroses, and glucoses bearing 2 to 30 ethylene oxide units and of at least one fatty acid containing a saturated or unsaturated, linear or branched C.sub.5 -C.sub.17 alkyl chain, the number of alkyl chains per polyol group being between 1 and 10, the mixture being stabilized with ionic amphiphilic lipid or lipids chosen from the group composed of those which impart a pH of between 5.5 and 7.5 to the dispersion.

Abstract translation: 囊泡由含有由至少一种选自含有1至60个环氧乙烷单元的聚乙二醇组成的组中的至少一种多元醇的混合物组成的非离子两亲性脂质混合物的脂质相制备，脱水山梨醇，含有2-60个 环氧乙烷单元，含有2至30个环氧乙烷单元的甘油，含有2至15个甘油单元的聚甘油，含有2至30个环氧乙烷单元的蔗糖和葡萄糖，以及至少一种含有饱和或不饱和直链或支链C5- C17烷基链，每个多元醇基团的烷基链数在1和10之间，混合物用离子两亲性脂质或选自由赋予分散体5.5至7.5的pH组成的组中的脂质稳定。

公开(公告)号：US5843476A

公开(公告)日：1998-12-01

申请号：US803146

申请日：1997-02-19

Applicant: Alain Ribier ,  Jean-Thierry Simonnet ,  Chantal Fanchon ,  Evelyne Segot ,  Herve Cantin

Inventor： Alain Ribier ,  Jean-Thierry Simonnet ,  Chantal Fanchon ,  Evelyne Segot ,  Herve Cantin

IPC: A61K9/127 ,  A61K8/00 ,  A61K8/14 ,  A61K8/19 ,  A61K8/25 ,  A61K8/30 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/36 ,  A61K8/368 ,  A61K8/37 ,  A61K8/39 ,  A61K8/40 ,  A61K8/44 ,  A61K8/49 ,  A61K8/63 ,  A61K8/64 ,  A61K8/66 ,  A61K8/68 ,  A61K8/72 ,  A61K8/73 ,  A61K8/81 ,  A61K8/92 ,  A61K8/96 ,  A61K8/97 ,  A61P3/04 ,  A61Q19/06 ,  A61Q90/00

CPC classification number: A61K8/14 ,  A61K8/368 ,  A61K8/4953 ,  A61K8/63 ,  A61Q19/06 ,  Y10S514/869 ,  Y10S514/909

Abstract: Compositions containing a first dispersion of lipid vesicles which are capable of penetrating into the deep layers of the skin and which contain at least one active agent chosen from lipolytic agents, draining agents and firming agents, for treating these deep layers, and a second dispersion of lipid vesicles which are capable of penetrating into the surface layers of the skin and which contain at least one active agent chosen from cutaneous surface treatment agents, exfoliation agents, smoothing agents and softening agents for the skin, for treating these surface layers, are effective as slimming agents for combating plumpness.

Abstract translation: 含有脂质囊泡的第一分散体的组合物能够渗入皮肤的深层并且含有至少一种选自脂肪分解剂，排液剂和紧肤剂的活性剂，用于处理这些深层，以及第二分散体 能够渗透到皮肤表层中并且含有选自皮肤表面处理剂，脱皮剂，平滑剂和皮肤软化剂中的至少一种活性剂用于处理这些表面层的脂质囊泡是有效的 减肥剂，以抵抗丰满度。

公开(公告)号：US5759526A

公开(公告)日：1998-06-02

申请号：US755314

申请日：1996-11-22

Applicant: Jean-Thierry Simonnet ,  Sylvie Legret ,  Alain Ribier, deceased ,  Roger Ribier, executor

Inventor： Jean-Thierry Simonnet ,  Sylvie Legret ,  Alain Ribier, deceased ,  Roger Ribier, executor

IPC: A61K8/14 ,  A61K8/46 ,  A61Q17/04 ,  A61K7/42 ,  A61K7/00 ,  A61K7/44

CPC classification number: A61Q17/04 ,  A61K8/14 ,  A61K8/466

Abstract: A composition comprising an aqueous dispersion of lipid vesicles encapsulating at least one compound which screens out UV radiation and contains at least one free or at least partially neutralized acidic function, wherein the lipid vesicles have a lipid membrane formed from at least one nonionic amphiphilic lipid (A) or from at least one saturated hydrocarbon ionic amphiphilic lipid (B) having an iodine number of less than 10, and from at least one totally neutralized ionic amphiphilic lipid (C) is disclosed. The use of this composition as a base for products to care for the skin, the scalp, the hair, the eyelashes or the eyebrows, as a base for make-up products, and more particularly as bases for compositions to protect the human epidermis, the hair, the eyelashes or the eyebrows against ultraviolet rays are also disclosed.

Abstract translation: 一种组合物，其包含脂质囊泡的水性分散体，其包封至少一种筛选紫外线辐射并且含有至少一种游离或至少部分中和的酸性功能的化合物，其中所述脂质囊泡具有由至少一种非离子两亲性脂质形成的脂质膜 A）或至少一种碘值小于10的饱和烃离子两亲性脂质（B）和至少一种完全中和的离子两亲性脂质（C）。 使用该组合物作为产品护理皮肤，头皮，头发，睫毛或眉毛的基质，作为化妆品的基质，更特别地，作为保护人类表皮的组合物的基质， 还公开了头发，睫毛或眉毛防紫外线。

公开(公告)号：US5658575A

公开(公告)日：1997-08-19

申请号：US301571

申请日：1994-09-07

Applicant: Alain Ribier ,  Jean-Thierry Simonnet ,  Jacqueline Griat

Inventor： Alain Ribier ,  Jean-Thierry Simonnet ,  Jacqueline Griat

IPC: A61K8/97 ,  A61K8/00 ,  A61K8/02 ,  A61K8/06 ,  A61K8/11 ,  A61K8/14 ,  A61K8/19 ,  A61K8/29 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/39 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61K8/58 ,  A61K8/60 ,  A61K8/67 ,  A61K8/72 ,  A61K8/73 ,  A61K8/89 ,  A61K8/92 ,  A61K9/107 ,  A61K9/127 ,  A61K9/51 ,  A61K45/00 ,  A61P17/00 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/08 ,  A61K7/00

CPC classification number: A61Q19/00 ,  A61K8/0295 ,  A61K8/06 ,  A61K8/062 ,  A61K9/107 ,  A61K9/1274 ,  B82Y5/00 ,  A61K2800/21 ,  A61K2800/413 ,  A61Q17/04 ,  A61Q19/005 ,  A61Q19/007 ,  A61Q19/08 ,  Y10S514/937 ,  Y10S514/938

Abstract: Cosmetic or dermatological compositions comprising an oil-in-water type emulsion containing oily globules which are coated with a lamellar liquid crystal coating and are dispersed in an aqueous phase, in which each oily globule contains at least one lipophilic compound which is cosmetically or dermatologically active and is individually coated with a monolamellar or oligolamellar layer of at least one lipophilic surface-active agent, at least one hydrophilic surface-active agent, and at least one fatty acid, the coated oily globules having a mean diameter of less than 500 nanometers, preferably less than 200 nanometers, and the oily phase contains a basic agent in the dissolved state, exhibit good skin and hair penetration.

Abstract translation: 化妆品或皮肤病学组合物，其包含油包水型乳剂，其含有层状液晶涂层并分散于水相中的油性水球，其中每个油性球包含至少一种在化学或皮肤病学活性中的亲油性化合物 并单独地涂覆有至少一种亲脂性表面活性剂，至少一种亲水性表面活性剂和至少一种脂肪酸的单层或多层膜，所述涂覆的油性小球的平均直径小于500纳米， 优选小于200纳米，油相含有溶解状态的碱性试剂，表现出良好的皮肤和毛发渗透性。