公开(公告)号：US11786364B2

公开(公告)日：2023-10-17

申请号：US17002284

申请日：2020-08-25

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Hernan Altman

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2/2412 ,  A61F2/2433 ,  A61F2/2466 ,  A61F2230/0067 ,  A61F2230/0091 ,  A61F2250/006

Abstract: A delivery apparatus for a medical device implant can include an outer catheter and a flexible delivery catheter. The outer catheter can have an axially extending shaft and a first lumen extending co-axially through the axially extending shaft. The flexible delivery catheter can have an elongate shaft having a flexible section extending along a distal portion of the elongate shaft, and the flexible section of the elongate shaft can be positioned or adjusted between a first, delivery configuration and a second, activated configuration. The delivery catheter can have a pull wire extending co-axially through a second lumen axially extending through the elongate shaft. A distal end of the pull wire can be fixedly secured or attached to the distal end of the elongate shaft.

公开(公告)号：US20230263628A1

公开(公告)日：2023-08-24

申请号：US18306842

申请日：2023-04-25

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David Maimon ,  Ron Sharoni ,  Tamir S. Levi ,  Emil Karapetian ,  Tri D. Tran ,  Tung T. Le

IPC: A61F2/24 ,  B21D41/04 ,  A61B50/30 ,  A61B17/06 ,  B23P11/00 ,  B21D41/00 ,  A61F2/00 ,  B25B27/10 ,  B23P19/04

CPC classification number: A61F2/2427 ,  A61B17/06 ,  A61B50/30 ,  A61F2/0095 ,  A61F2/243 ,  A61F2/2433 ,  B21D41/00 ,  B21D41/04 ,  B23P11/00 ,  B23P19/04 ,  B25B27/10 ,  A61F2/9522 ,  Y10T29/5367 ,  Y10T29/53552 ,  Y10T29/53578

Abstract: A device for crimping a radially expandable and collapsible prosthetic valve comprises a crimping loop having a first end portion, a second end portion, and a loop portion extending between the first and second end portions and defining an opening configured to receive the prosthetic valve. The crimping loop is movable between a first state in which the opening has a first diameter and a second state in which the opening has a second diameter smaller than the first diameter such that when the prosthetic valve is positioned within the loop portion, movement of the crimping loop from the first state to the second state is effective to reduce a diameter of the prosthetic valve. A method for crimping a prosthetic valve comprises reducing a diameter of an opening of a crimping loop, thereby radially compressing an at least partially expanded prosthetic valve disposed within the opening.

公开(公告)号：US11723771B2

公开(公告)日：2023-08-15

申请号：US17150355

申请日：2021-01-15

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Noam Nir ,  Tomer Saar

IPC: A61F2/24

CPC classification number: A61F2/2454 ,  A61F2/243 ,  A61F2/2466 ,  A61F2/2487 ,  A61F2/2457 ,  A61F2002/249

Abstract: A method for improving leaflet prolapse and/or valve regurgitation associated with a heart valve involves delivering a spacer device into a ventricle of a heart using a delivery system comprising a catheter, fixing the spacer device to a wall of the ventricle, expanding the spacer device to reposition a papillary muscle disposed in the ventricle away from the wall, the papillary muscle being connected to a leaflet of an atrioventricular heart valve via chordae tendineae, and releasing the spacer device from the catheter.

公开(公告)号：US20230086571A1

公开(公告)日：2023-03-23

申请号：US18058708

申请日：2022-11-23

Applicant: Edwards Lifesciences Corporation

Inventor： Ofir Witzman ,  Eitan Atias ,  Hanoch Cohen-Tzemach ,  David Maimon

IPC: A61B17/122

Abstract: Methods and tools for folding and/or capturing leaflets of a heart valve are disclosed herein. Prior to or during installing of a prosthetic heart valve, part of a leaflet of an existing valvular structure can be positioned distally and/or folded upon itself. The existing valvular structure may be a native heart valve or a previously-implanted prosthetic heart valve. When the existing valvular structure is at the aortic position, the prosthetic heart valve can be subsequently installed within the existing valvular structure such that the leaflet is maintained in a location that avoids obstructing blood flow to one or more of the coronary arteries.

公开(公告)号：US20230077068A1

公开(公告)日：2023-03-09

申请号：US17932654

申请日：2022-09-15

Applicant: Edwards Lifesciences Corporation

Inventor： Ilan Tamir ,  David Maimon ,  Hanoch Cohen-Tzemach ,  Adva Alon ,  Amir Keret ,  Eyal Leiba ,  Boaz Manash ,  Sean Chow ,  Ziv Yohanan ,  Shay Zarneger

IPC: A61F2/24 ,  A61B17/3205 ,  A61B18/14 ,  A61B17/32 ,  A61B17/34

Abstract: Methods and tools for implanting prosthetic heart valves and modifying leaflets of an existing valvular structure in a subject are disclosed herein. Prior to or during implantation of the prosthetic heart valve within the existing valvular structure, each tool can be provided in the ascending aorta (or equivalent thereof) of a subject and can be used to pierce, lacerate, slice, tear, cut or otherwise modify a leaflet or commissure of the existing valvular structure. The existing valvular structure can be a native aortic valve or other native heart valve, or a previously-implanted prosthetic heart valve. The modification can avoid, or at least reduce the likelihood of, issues that leaflets of the existing valvular structure might otherwise cause once the prosthetic heart valve has been fully installed, for example, obstruction of blood flow to the coronary arteries and/or improper valve mounting due to a non-circular cross-section.

公开(公告)号：US20220370198A1

公开(公告)日：2022-11-24

申请号：US17881042

申请日：2022-08-04

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Elena Sherman ,  Michael Bukin ,  Tamir S. Levi ,  Ziv Yohanan ,  David Maimon

IPC: A61F2/24

Abstract: An assembly and associated method for a commissure of a prosthetic heart valve is disclosed. As one example, a method includes forming a plurality of commissures with a plurality of leaflets of a prosthetic heart valve, wherein each commissure is formed by: folding each commissure tab of each leaflet into a series of overlapping layers, each folded commissure tab arranged outward of, in a lateral direction, a portion of a body of the leaflet that is directly connected to the commissure tab; pairing each folded commissure tab of each leaflet with a folded commissure tab of another leaflet; and securing at least a portion of the series of overlapping layers of each folded commissure tab in its folded configuration.

公开(公告)号：US20220280295A1

公开(公告)日：2022-09-08

申请号：US17750826

申请日：2022-05-23

Applicant: Edwards Lifesciences Corporation

Inventor： Anatoly Dvorsky ,  David Maimon ,  Dikla Kersh ,  Gideon Sagi

IPC: A61F2/24

Abstract: An implantable prosthetic device can include a frame that is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The frame can include a plurality of struts, each strut comprising a first portion and a second portion separated by a deflection point. Each strut can be curved helically with respect to a first, longitudinal axis of the frame. The first portion of each strut can be curved in a first direction with respect to a first line parallel to a second axis that is perpendicular to the first, longitudinal axis of the frame, and the second portion of each strut can be curved in a second direction with respect to a second line parallel to the second axis.

公开(公告)号：US11291540B2

公开(公告)日：2022-04-05

申请号：US16034794

申请日：2018-07-13

Applicant: Edwards Lifesciences Corporation

Inventor： Liron Tayeb ,  Eran Goldberg ,  David Maimon ,  Adi Carmi ,  Arie Tylis ,  Ofir Witzman ,  Ralph Schneider ,  Mohammad Jafari ,  Hengchu Cao ,  Eason Michael Abbott ,  Dustin P. Armer ,  Michael D. Franklin ,  Tomer Saar ,  Anatoly Dvorsky ,  John J. Desrosiers ,  Daniel James Murray ,  Michael G. Valdez ,  Assaf Bash ,  Amir Blumenfeld ,  Noa Axelrod ,  Eitan Atias

IPC: A61F2/24 ,  A61F2/90 ,  A61F2/88

Abstract: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.

公开(公告)号：US20220031453A1

公开(公告)日：2022-02-03

申请号：US17502018

申请日：2021-10-14

Applicant: Edwards Lifesciences Corporation

Inventor： Ziv Yohanan ,  Tamir S. Levi ,  David Maimon ,  Michael G. Valdez ,  Tram Ngoc Nguyen

IPC: A61F2/24

Abstract: An implantable prosthetic valve can include an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration. A leaflet structure can be positioned within the frame and secured thereto. An outer skirt can be positioned around an outer surface of the frame and secured to the frame and an annular sealing member can be positioned around an outer surface of the outer skirt and secured to the outer skirt.

公开(公告)号：US20210393398A1

公开(公告)日：2021-12-23

申请号：US17466331

申请日：2021-09-03

Applicant: Edwards Lifesciences Corporation

Inventor： Tamir S. Levi ,  Noam Nir ,  Michael Bukin ,  David Maimon ,  Haim Yushtein

IPC: A61F2/24

Abstract: A prosthetic heart valve includes an annular frame that is radially collapsible and radially expandable, a plurality of leaflets situated within the frame, each leaflet having opposing commissure tab portions on opposite sides of the leaflet, each commissure tab portion paired with an adjacent commissure tab portion of an adjacent leaflet to form at least one commissure, and a plurality of post members mounted on an interior surface of the frame. The at least one commissure includes a commissure attachment assembly including a support member disposed at least partially around the commissure tab portions and the commissure tab portions are folded around the support member. The commissure attachment assembly is secured to a first post member of the plurality of post members such that the commissure tab portions are positioned between the first post member and the support member.