公开(公告)号：US20090171170A1

公开(公告)日：2009-07-02

申请号：US12343792

申请日：2008-12-24

申请人： Li Li ,  Scott Amundson ,  Corydon A. Hinton

发明人： Li Li ,  Scott Amundson ,  Corydon A. Hinton

IPC分类号： A61B5/00

CPC分类号： A61B5/00 ,  A61B5/0002 ,  A61B5/14551 ,  A61B5/746 ,  A61B2562/085

摘要： In an embodiment, a system is provided that includes a sensor configured to monitor a physiological parameter of the patient. The sensor is further configured to communicate with a portable electronic device configured to communicate over a wireless network. A method of operation of a sensor is provided that includes receiving data from a sensor configured to sense a physiological parameter and determining the physiological parameter from the data. A method of operation of a portable electronic device is also provided.

摘要翻译： 在一个实施例中，提供了一种系统，其包括被配置为监测患者的生理参数的传感器。 传感器还被配置为与被配置为通过无线网络进行通信的便携式电子设备进行通信。 提供了一种传感器的操作方法，其包括从配置成感测生理参数并根据数据确定生理参数的传感器接收数据。 还提供了一种便携式电子设备的操作方法。

公开(公告)号：US07549876B2

公开(公告)日：2009-06-23

申请号：US12229349

申请日：2008-08-21

申请人： Qi-Jun Zhao ,  Li Li ,  Hua Yin

发明人： Qi-Jun Zhao ,  Li Li ,  Hua Yin

IPC分类号： H01R13/62

CPC分类号： G06K13/08 ,  G06K7/0021

摘要： An electrical card connector (100) for insertion of an electrical card (200) comprises an insulative housing (1), a plurality of terminals (2) coupled to the insulative housing and a first shell (4). The insulative housing comprises a base portion (11), an arm portion (12) extending from a lateral side of the base portion, and a receiving space (13) formed between the base portion and the arm portion to receive the electrical card. The terminals are coupled to the base portion and extend into the receiving space for electrical connection to the electrical card. The first shell (4) is integrally molded with the insulative housing (1) and covers the insulative housing.

摘要翻译： 用于插入电卡（20​​0）的电子卡连接器（100）包括绝缘壳体（1），耦合到绝缘壳体的多个端子（2）和第一壳体（4）。 绝缘壳体包括基部（11），从基部的侧面延伸的臂部（12）和形成在基部和臂部之间以容纳电卡的容纳空间（13）。 端子耦合到基部并延伸到接收空间中以电连接到电卡。 第一壳体（4）与绝缘壳体（1）整体模制并覆盖绝缘壳体。

公开(公告)号：US20090156419A1

公开(公告)日：2009-06-18

申请号：US12162286

申请日：2007-02-06

申请人： Huafang Gao ,  Ze Li ,  Dong Wang ,  Yanhua Liu ,  Xiang Liu ,  Yangzhou Jiang ,  Li Li ,  Chuanzan Zhao ,  Gengxin Lan ,  Tao Guo ,  Bin Cai ,  Jing Cheng

发明人： Huafang Gao ,  Ze Li ,  Dong Wang ,  Yanhua Liu ,  Xiang Liu ,  Yangzhou Jiang ,  Li Li ,  Chuanzan Zhao ,  Gengxin Lan ,  Tao Guo ,  Bin Cai ,  Jing Cheng

IPC分类号： C40B30/04

CPC分类号： C12Q1/6881 ,  C12Q1/6832 ,  C12Q2600/156 ,  C12Q2535/131 ,  C12Q2527/107

摘要： The present invention provides an improved nucleic acid hybridization process employing a modified oligonucleotide probe comprising naturally occurring nucleotide bases. At least one nucleotide in the modified oligonucleotide is artificially mismatched relative to the control nucleic acid in addition to any mismatches arising from a variant nucleic acid target containing a sequence variation. The artificial mismatch and the sequence variation positions are separated from one another on the oligonucleotide by six to nine nucleotide positions.

摘要翻译： 本发明提供使用包含天然存在的核苷酸碱基的修饰的寡核苷酸探针的改进的核酸杂交方法。 除了由含有序列变异的变体核酸靶产生的任何错配之外，修饰寡核苷酸中至少一个核苷酸相对于对照核酸人为错配。 将人工错配和序列变异位置在寡核苷酸上彼此分开6至9个核苷酸位置。

公开(公告)号：US20090142317A1

公开(公告)日：2009-06-04

申请号：US12325464

申请日：2008-12-01

申请人： Tinghua Cao ,  Li Li

发明人： Tinghua Cao ,  Li Li

IPC分类号： A61K35/12

CPC分类号： A61K39/001 ,  A61K38/14 ,  A61K2039/5158

摘要： Disclosed in this specification is a process for producing ex vivo expanded CD4+CD25+ regulatory T cells. The process includes the steps of extracting a sample that includes peripheral blood mononuclear cells from a human donor. The extracted cells include a certain number of cells which are CD4+CD25+ regulatory T cells. The relative population of the CD4+CD25+ regulatory T cells is enhanced such that the Treg cells constitute the majority of the cells in the sample. Thereafter, the population of the enriched Treg cells, that may include third-party derived Treg cells, is expanded to produce a clinically meaningful population of cells for use in the treatment of GVHD.

摘要翻译： 在本说明书中公开的是制备离体扩增的CD4 + CD25 +调节性T细胞的方法。 该方法包括从人供体中提取包含外周血单核细胞的样品的步骤。 提取的细胞包括一定数量的CD4 + CD25 +调节性T细胞的细胞。 增加CD4 + CD25 +调节性T细胞的相对群体，使得Treg细胞构成样品中的大部分细胞。 此后，扩增可能包括第三方衍生的Treg细胞的富集的Treg细胞的群体，以产生用于治疗GVHD的临床有意义的细胞群。

公开(公告)号：US20090118598A1

公开(公告)日：2009-05-07

申请号：US12348742

申请日：2009-01-05

申请人： Carine Hoarau ,  Li Li

发明人： Carine Hoarau ,  Li Li

IPC分类号： A61B5/1455 ,  A61B5/00 ,  A61B5/11

CPC分类号： A61B5/6826 ,  A61B5/14552 ,  A61B5/6838

摘要： A sensor may be adapted to provide output to indicate when the sensor experiences abnormal forces or pressure. The forces may be outside forces, or the forces may be generated by patient motion. A sensor system as provided may also be adapted to correct for such forces when calculating measurements related to a physiological characteristic.

摘要翻译： 传感器可以适于提供输出以指示传感器何时经历异常的力或压力。 力可能是外力，或者力可以由患者运动产生。 所提供的传感器系统还可以适于在计算与生理特征相关的测量时校正这种力。

公开(公告)号：US07521041B2

公开(公告)日：2009-04-21

申请号：US11974318

申请日：2007-10-12

申请人： Mathai Mammen ,  Yu-Hua Ji ,  YongQi Mu ,  Craig Husfeld ,  Li Li

发明人： Mathai Mammen ,  Yu-Hua Ji ,  YongQi Mu ,  Craig Husfeld ,  Li Li

IPC分类号： A61K49/00 ,  A61K31/44 ,  G01N33/53

CPC分类号： C07D211/62 ,  A61K9/124 ,  A61K9/1623 ,  A61K9/1652 ,  A61K31/4545 ,  A61K45/06 ,  C07D401/12

摘要： This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.

公开(公告)号：US20090081877A1

公开(公告)日：2009-03-26

申请号：US12326834

申请日：2008-12-02

申请人： Li Li ,  Bradley J. Howard

发明人： Li Li ,  Bradley J. Howard

IPC分类号： H01L21/3065

CPC分类号： G03F7/40 ,  G03F7/405 ,  H01L21/0273 ,  H01L21/31116 ,  H01L21/31144

摘要： A method for controlling striations and CD loss in a plasma etching method is disclosed. During the etching process, the substrate of semiconductor material to be etched is exposed first to plasma under a low power strike and subsequently to a conventional high power strike. CD loss has been found to be reduced by about 400 Angstroms and striations formed in the contact holes are reduced.

摘要翻译： 公开了一种用于控制等离子体蚀刻方法中的条纹和CD损耗的方法。 在蚀刻工艺期间，待蚀刻的半导体材料的衬底首先在低功率冲击下暴露于等离子体，然后暴露于传统的高功率冲击。 已经发现CD损耗减少约400埃，并且在接触孔中形成的条纹减小。

公开(公告)号：US20090069335A1

公开(公告)日：2009-03-12

申请号：US12231861

申请日：2008-09-05

申请人： YuHua Ji ,  Craig Husfeld ,  YongQi Mu ,  Rick Lee ,  Li Li

发明人： YuHua Ji ,  Craig Husfeld ,  YongQi Mu ,  Rick Lee ,  Li Li

IPC分类号： A61K31/496 ,  C07D241/04 ,  A61K31/495 ,  C07D207/02 ,  A61K31/40 ,  C07D211/06 ,  A61K31/444 ,  C07D409/02 ,  A61K31/4535 ,  C07D405/02 ,  A61K31/4525 ,  A61P11/00

CPC分类号： C07D333/24 ,  C07D209/14 ,  C07D213/38 ,  C07D231/12 ,  C07D277/28 ,  C07D295/13 ,  C07D307/52 ,  C07D307/81 ,  C07D317/58 ,  C07D333/20 ,  C07D333/58

摘要： The invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein R1-3, R5-7, a, X, Y, Y′, Y″, and Z are as defined in the specification. These compounds are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes for preparing such compounds and methods of using such compounds to, for example, treat pulmonary disorders such as chronic obstructive pulmonary disease and asthma.

摘要翻译： 本发明提供式I化合物或其药学上可接受的盐，其中R1-3，R5-7，a，X，Y，Y'，Y“和Z如说明书中所定义。 这些化合物是毒蕈碱受体拮抗剂。 本发明还提供含有这些化合物的药物组合物，制备这些化合物的方法和使用这些化合物例如治疗慢性阻塞性肺疾病和哮喘等肺疾病的方法。

公开(公告)号：US07502329B2

公开(公告)日：2009-03-10

申请号：US10351913

申请日：2003-01-27

申请人： Li Li ,  Sanjoy Paul ,  Marina K. Thottan ,  Bin Yao

发明人： Li Li ,  Sanjoy Paul ,  Marina K. Thottan ,  Bin Yao

IPC分类号： H04L12/28 ,  H04L12/403 ,  H04J3/16 ,  G06F15/173

CPC分类号： H04L43/10 ,  H04L41/0213 ,  H04L41/046 ,  H04L41/0896 ,  H04L41/5009

摘要： A method and apparatus for optimizing a distributed polling system in a network comprising a plurality of nodes. The method includes identifying bandwidth constraints on polling traffic for each of the plurality of nodes. Selecting, from a plurality of unpolled nodes within the plurality of nodes, at least one poller node according to a maximum number of unpolled nodes assignable to each of the at least one poller node without violating bandwidth constraints, and respectively assigning the unpolled nodes as pollee nodes to the at least one poller node. The apparatus includes a central manager and a plurality of pollee nodes coupled to at least one poller node via at least one routing path. At least one aggregating node is coupled to the at least one poller nodes, where the aggregating node is further coupled to the central manager.

摘要翻译： 一种用于优化包括多个节点的网络中的分布式轮询系统的方法和装置。 该方法包括识别对于多个节点中的每个节点的轮询业务的带宽约束。 根据可分配给所述至少一个轮询器节点中的每一个的最大数量的未被校准的节点，在多个节点内从多个未完成节点中选择至少一个轮询器节点，而不违反带宽限制，以及分别将未被校准的节点分配为轮询 节点到至少一个轮询器节点。 该装置包括中央管理器和经由至少一个路由路径耦合到至少一个轮询器节点的多个轮询节点。 至少一个聚合节点耦合到至少一个轮询器节点，其中聚合节点进一步耦合到中央管理器。

公开(公告)号：US20090010234A1

公开(公告)日：2009-01-08

申请号：US12124332

申请日：2008-05-21

申请人： Li Li ,  Harish Viswanathan ,  Ramachandran Ramjee

发明人： Li Li ,  Harish Viswanathan ,  Ramachandran Ramjee

IPC分类号： H04Q7/24

CPC分类号： H04W40/02 ,  H04L1/0002 ,  H04L1/0057 ,  H04L45/125 ,  H04W40/34 ,  H04W72/1263 ,  Y02D70/142 ,  Y02D70/22 ,  Y02D70/30

摘要： A routing protocol, according to one embodiment of which a first station of a wireless network monitors its outgoing transmissions corresponding to a traffic flow for occurrence of multi-tier signals and for ability to achieve a specified minimum transmission rate. Based on the monitoring, the first station may transmit an outgoing solicitation message that identifies the monitored traffic flow as a candidate for rerouting. Upon receipt of the solicitation message, a second station of the wireless network evaluates whether rerouting of the monitored traffic flow through the second station is capable of increasing data throughput for that traffic flow without decreasing data throughputs for other traffic flows presently handled by the second station. Based on this evaluation, the second station may transmit to the first station an offer to reroute the monitored traffic flow. The first station, in turn, evaluates this offer, e.g., by comparing its benefits with those of alternative offers that the first station might have received from other stations of the wireless network in response to the solicitation message. Based on the latter evaluation, the first station may reroute the monitored traffic flow through the station whose offer is deemed preferable.

摘要翻译： 根据一个实施例的路由协议，无线网络的第一站监视其对应于业务流的出局传输以发生多层信号，并且能够实现指定的最小传输速率。 基于监视，第一站可以将识别被监视的业务流的传出请求消息作为重新路由的候选者发送。 在接收到请求消息时，无线网络的第二站评估通过第二站的所监视的业务流的重新路由是否能够增加该业务流的数据吞吐量，而不减少目前由第二站处理的其他业务流的数据吞吐量 。 基于该评估，第二站可以向第一站发送重新路由所监视的业务流的报价。 反过来，第一站又通过将其优点与第一站可能响应于该请求消息从无线网络的其他站接收到的替代提供的优点进行比较来评估该提供。 基于后一种评估，第一站可以将监视的​​业务流重新路由通过被认为优选的站。