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公开(公告)号：US06800076B2
公开(公告)日：2004-10-05
申请号：US09982549
申请日：2001-10-18
Applicant: Mark Humayun
Inventor： Mark Humayun
IPC: A61B1818
CPC classification number: A61M1/008 , A61B2090/3614 , A61B2090/3937 , A61F9/007 , A61M13/003 , A61M2210/0612
Abstract: A surgical device having a body portion that is gripped by a user, the body portion having a distal end equipped with a soft tip and the proximal end optionally connected to an external vacuum or gas/air source. The surgical device is particularly suitable for use in ophthalmic surgical procedures to remove fluid from the eye or introduce gas/air into the eye. The soft tip is fabricated to protect the delicate tissues if the eye and is further modified so as to enhance a user's visibility of the device in the surgical field.
Abstract translation: 一种手术装置，其具有被使用者抓握的主体部分，所述主体部分具有配备有软尖端的远端，并且所述近端可选地连接到外部真空或气体/空气源。 手术装置特别适合用于眼科外科手术以从眼睛中除去流体或将气体/空气引入眼睛。 制造软尖端以保护精细的组织，如果眼睛被进一步修改以增强使用者在手术领域中的装置的可视性。
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公开(公告)号：US10478206B2
公开(公告)日：2019-11-19
申请号：US14114160
申请日：2012-04-27
Applicant: Mark Humayun , Ashish Ahuja , Yu-Chong Tai , Robert Grubbs , Rodrigo Brant , Trent Wells , Lincoln Vallance Johnson , Sherry T. Hikita , David Hinton
Inventor： Mark Humayun , Ashish Ahuja , Yu-Chong Tai , Robert Grubbs , Rodrigo Brant , Trent Wells , Lincoln Vallance Johnson , Sherry T. Hikita , David Hinton
IPC: A61B17/29 , A61F9/007 , A61L27/16 , A61L27/34 , A61L27/38 , A61L27/50 , A61K35/50 , C12N5/079 , A61F2/14 , A61F2/46 , A61F9/00 , A61M1/12 , A61M5/14 , A61B17/30
Abstract: Disclosed herein are instruments and methods for delivery of substrates, including cell-seeded substrates, to target tissues requiring treatment for various diseases that induce cell death, damage or loss of function. The substrates are configured to provide cells, including stem cells, with a structural support that allows interconnection with and transmission of biological signals between the cells and the target tissue.
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公开(公告)号：US09987417B2
公开(公告)日：2018-06-05
申请号：US14706498
申请日：2015-05-07
Applicant: Jason Shih , Yu-Chong Tai , Changlin Pang , Sean Caffey , Raymond Peck , Fukang Jiang , Mark Humayun
Inventor： Jason Shih , Yu-Chong Tai , Changlin Pang , Sean Caffey , Raymond Peck , Fukang Jiang , Mark Humayun
IPC: A61M1/00 , A61M5/142 , A61F9/00 , A61M39/02 , A61M5/36 , A61M5/14 , A61M5/148 , A61M5/168 , A61M39/00
CPC classification number: A61M5/14212 , A61F9/0017 , A61M5/14276 , A61M5/148 , A61M5/16881 , A61M5/36 , A61M39/0208 , A61M2005/1403 , A61M2039/0072 , A61M2039/0081 , A61M2039/0235 , A61M2209/045
Abstract: In various embodiments, a tool is employed in filling a drug-delivery device. The tool may include, for example, a needle that is admitted through a fill port of the drug-delivery device.
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公开(公告)号：US09623174B2
公开(公告)日：2017-04-18
申请号：US12463265
申请日：2009-05-08
Applicant: Changlin Pang , Jason Shih , Fukang Jiang , Sean Caffey , Mark Humayun , Yu-Chong Tai
Inventor： Changlin Pang , Jason Shih , Fukang Jiang , Sean Caffey , Mark Humayun , Yu-Chong Tai
CPC classification number: A61M5/14276 , A61F9/00781 , A61M5/148 , A61M5/16804 , A61M5/16854 , A61M2005/14204 , A61M2205/3331 , A61M2205/3368 , A61M2210/0612 , A61M2210/0693
Abstract: In various embodiments, an implantable pump includes a cannula. The pump (e.g., the cannula thereof) may include, for example, flow sensors, pressure sensors, filters, and/or other components.
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公开(公告)号：US20160256266A1
公开(公告)日：2016-09-08
申请号：US15062549
申请日：2016-03-07
Applicant: Craig Alan CABLE, III , Charles DeBoer , Yu-Chong Tai , Mark Humayun , Sean Caffey
Inventor： Craig Alan CABLE, III , Charles DeBoer , Yu-Chong Tai , Mark Humayun , Sean Caffey
IPC: A61F2/16
CPC classification number: A61F2/1635 , A61F2002/1682 , A61F2002/169 , A61F2002/1699 , A61F2310/00011
Abstract: An accommodating intraocular lens has a central chamber with an optical axis extending through a vision-correcting optical zone and a peripheral region at least partially surrounding the optical zone but not interfering with light passing therethrough. At least one peripheral chamber surrounds the central chamber at least partially and functions as a storage reservoir for optical fluid, receiving excess fluid when the central chamber is compressed. Within each peripheral chamber (if there is more than one), a shape-retention member resists collapse of the peripheral chamber in response to external force.
Abstract translation: 容纳人工晶状体具有中心室，其中光轴延伸通过视觉校正光学区域和至少部分地围绕光学区域但不干扰穿过其中的光的外围区域。 至少一个周边室至少部分地围绕中央室，并且用作光学流体的储存容器，当中心室被压缩时接收多余的流体。 在每个周边室内（如果存在多于一个），形状保持构件抵抗外力响应于外力而塌陷。
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Patent Agency Ranking
公开(公告)号：US20160158059A1
公开(公告)日：2016-06-09
申请号：US14295102
申请日：2014-06-03
Applicant: Yu-Chong Tai , Mark Humayun , Jason Shih
Inventor： Yu-Chong Tai , Mark Humayun , Jason Shih
CPC classification number: A61F9/0017 , A61K9/0024 , A61K9/0097 , A61M5/14276 , A61M5/14593 , A61M5/155 , A61M5/16877 , A61M5/16881 , A61M37/00 , A61M2005/14204 , A61M2205/0244 , A61M2205/3507 , A61M2207/00 , A61M2210/0612 , B81B2201/058 , B81C1/00119 , B81C2201/019 , F04B43/043 , F16K99/0001 , F16K99/0005 , F16K99/0034 , F16K99/0057 , F16K2099/008 , F16K2099/0088 , Y10T29/49236
Abstract: Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. The cannula is shaped to facilitate insertion thereof into a patient's eyeball.
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公开(公告)号：US09162024B2
公开(公告)日：2015-10-20
申请号：US12463255
申请日：2009-05-08
Applicant: Changlin Pang , Fukang Jiang , Jason Shih , Sean Caffey , Mark Humayun , Yu-Chong Tai , Jeffrey Brennan , Raymond Peck
Inventor： Changlin Pang , Fukang Jiang , Jason Shih , Sean Caffey , Mark Humayun , Yu-Chong Tai , Jeffrey Brennan , Raymond Peck
CPC classification number: A61F9/00781 , A61F9/0017 , A61M5/1408 , A61M5/142 , A61M5/14276 , A61M5/14593 , A61M5/16886 , A61M39/24 , A61M2005/14204 , A61M2005/14264 , A61M2205/0244 , A61M2210/0612 , B44C1/227 , Y10T156/1092 , Y10T156/1093 , Y10T307/625
Abstract: Embodiments of an implantable electrolytic pump include a drug reservoir, a cannula fluidly coupled to the reservoir, a pumping mechanism for forcing liquid from the reservoir through the cannula, control circuitry for operating the pumping mechanism, and a power source comprising primary and auxiliary batteries in a stacked configuration, only the main battery being operatively coupled to the control circuitry during normal operation, the control circuitry operatively coupling the back-up battery upon detection of an electrical fault. The pump may further include a hermetic enclosure containing the control circuitry and the power source.
Abstract translation: 可植入电解泵的实施例包括药物储存器，流体地联接到储存器的套管，用于迫使来自储存器的液体通过套管的泵送机构，用于操作泵送机构的控制电路，以及包括主电池和辅助电池的电源 堆叠配置，在正常操作期间只有主电池可操作地耦合到控制电路，所述控制电路在检测到电气故障时可操作地耦合备用电池。 泵还可以包括包含控制电路和电源的密封外壳。
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98.发明授权公开(公告)号：US08903476B2
公开(公告)日：2014-12-02
申请号：US12718188
申请日：2010-03-05
Applicant: Jeffrey Brennan , Mark Humayun , Sean Caffey
Inventor： Jeffrey Brennan , Mark Humayun , Sean Caffey
CPC classification number: A61B5/0066 , A61B3/10 , A61B3/102 , A61B3/14 , A61B5/0073 , A61B5/415 , A61B5/418 , A61B5/6852 , A61B8/12 , A61B8/4245 , A61B8/5276 , A61B18/20 , A61B34/20 , A61B2017/00207 , A61B2017/00694 , A61B2034/2048 , A61B2034/2051 , A61B2090/061 , A61B2090/3735 , A61B2090/3954 , A61M25/01 , A61M2025/0166 , A61N5/00 , Y10T29/49826
Abstract: A device includes a handpiece having a probe tip disposed at an end thereof, and, connected to the handpiece such that, at the probe tip, a functionality of each is provided, a plurality of optical coherence tomography (OCT) probes.
Abstract translation: 一种装置包括具有设置在其端部的探针尖端的手持件，并且连接到所述手持件，使得在所述探针尖端处提供每个的功能，多个光学相干断层摄影（OCT）探针。
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99.发明授权Methods of determining motion and distance during medical and veterinary procedures 有权在医疗和兽医程序中确定运动和距离的方法公开(公告)号：US08892191B2
公开(公告)日：2014-11-18
申请号：US12718272
申请日：2010-03-05
Applicant: Jeffrey Brennan , Mark Humayun , Sean Caffey
Inventor： Jeffrey Brennan , Mark Humayun , Sean Caffey
IPC: A61B6/00 , A61B8/08 , A61B5/00 , A61B18/20 , A61B17/00 , A61M25/01 , A61N5/00 , A61B19/00 , A61B8/12
CPC classification number: A61B5/0066 , A61B3/10 , A61B3/102 , A61B3/14 , A61B5/0073 , A61B5/415 , A61B5/418 , A61B5/6852 , A61B8/12 , A61B8/4245 , A61B8/5276 , A61B18/20 , A61B34/20 , A61B2017/00207 , A61B2017/00694 , A61B2034/2048 , A61B2034/2051 , A61B2090/061 , A61B2090/3735 , A61B2090/3954 , A61M25/01 , A61M2025/0166 , A61N5/00 , Y10T29/49826
Abstract: A system, for use with a cannula insertable into human or animal tissue, for measuring relative motion during a surgical procedure includes a probe having a probe tip insertable into the cannula, and means for determining relative motion between the cannula and the probe tip.
Abstract translation: 用于在插入人体或动物组织中的套管用于在外科手术过程中测量相对运动的系统包括具有可插入插管中的探针尖端的探针以及用于确定插管与探针针尖之间的相对运动的装置。
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公开(公告)号：US08684997B2
公开(公告)日：2014-04-01
申请号：US13541012
申请日：2012-07-03
Applicant: Changlin Pang , Fukang Jiang , Jason Shih , Sean Caffey , Mark Humayun , Yu-Chong Tai
Inventor： Changlin Pang , Fukang Jiang , Jason Shih , Sean Caffey , Mark Humayun , Yu-Chong Tai
CPC classification number: A61F9/00781 , A61F9/0017 , A61M5/1408 , A61M5/142 , A61M5/14276 , A61M5/14593 , A61M5/16886 , A61M39/24 , A61M2005/14204 , A61M2005/14264 , A61M2205/0244 , A61M2210/0612 , B44C1/227 , Y10T156/1092 , Y10T156/1093 , Y10T307/625
Abstract: Embodiments of an implantable electrolytic pump include an electrolysis chamber, a drug chamber and an osmosis chamber, the osmosis chamber having a first portion in contact with the drug chamber and a second portion exposed to facilitate contact with a surrounding fluid. The pump further includes a cannula for conducting liquid from the drug chamber and electrolysis electrodes within the electrolysis chamber for causing generation of a gas therein, the electrolysis and drug chambers being in contact such that gas electrolysis within electrolysis chamber forces fluid from the drug chamber into the cannula, contact between the drug chamber and the osmosis chamber permitting fluid admitted into the osmotic chamber from the surrounding fluid to offset volume loss from the drug chamber and prevent buildup of vacuum pressure thereon.
Abstract translation: 可植入电解泵的实施例包括电解室，药物室和渗透室，渗透室具有与药物室接触的第一部分和暴露于便于与周围流体接触的第二部分。 泵还包括用于从药物腔室导出液体的插管和电解室内的电解电极，用于在其中产生气体，电解和药物室接触，使得电解室内的气体电解迫使来自药物室的流体进入 插管，药物室和渗透室之间的接触，允许从周围流体进入渗透室的流体以抵消药物室的体积损失并防止其上的真空压力的累积。
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