MEASUREMENT WITH MULTIPLEXED DETECTION
    91.
    发明申请
    MEASUREMENT WITH MULTIPLEXED DETECTION 审中-公开
    测量多重检测

    公开(公告)号:US20090306519A1

    公开(公告)日:2009-12-10

    申请号:US12375047

    申请日:2007-07-16

    IPC分类号: A61B6/00

    摘要: The invention relates to a device (1) for imaging an interior of a turbid medium (45) comprising: a) a measurement volume (15) for receiving the turbid medium (45); b) a light source (5) for irradiating the turbid medium (45); c) a photodetector unit (10) for detecting light emanating from exit positions (60) located on a boundary of the measurement volume (15) as a result of >irradiating the turbid medium (45). The device (1) is adapted to collect light from spatially distinct beams of light emanating from a single exit position (60). The single exit position (60) may, for instance, come in the form of an optical channel (25b) or it may simply be an area of skin tissue from which light emanates. In one embodiment of the device (1) according to the invention multiple optical light guides (55) are optically coupled to the single exit position (60).

    摘要翻译: 本发明涉及一种用于对浑浊介质(45)内部进行成像的装置(1),包括:a)用于接收混浊介质的测量体积(15); b)用于照射混浊介质(45)的光源(5); c)用于检测从位于测量体积(15)的边界上的出口位置(60)发出的光的光电检测器单元(10),作为>照射混浊介质(45)的结果。 装置(1)适于收集从单个出口位置(60)发出的空间上不同的光束的光。 单个出口位置(60)可以例如以光学通道(25b)的形式,或者它可以简单地是光发出的皮肤组织的区域。 在根据本发明的装置(1)的一个实施例中,多个光学光导(55)光耦合到单个出口位置(60)。

    Method and Device for Optical Imaging of a Turbid Medium
    93.
    发明申请
    Method and Device for Optical Imaging of a Turbid Medium 有权
    浊度介质的光学成像方法和装置

    公开(公告)号:US20080300472A1

    公开(公告)日:2008-12-04

    申请号:US12094670

    申请日:2006-11-17

    IPC分类号: A61B5/1455

    摘要: Disclosed is a method and a device for optical imaging of a turbid medium. This method comprises a reference measurement of reference intensities of light emanating from the turbid medium at a reference blood oxygen saturation (SaO2) in the turbid medium and a reference imaging step for reconstructing a reference image of the turbid medium from the measured reference intensities. Furthermore the method comprises a contrast measurement of the contrast intensity of the light emanating from the turbid medium at a contrast blood oxygen saturation (SaO2) level in the turbid medium and a contrast imaging step for reconstructing a contrast image of the turbid medium from the measured contrast intensities. A comparison is made between the contrast image to the reference image of the turbid medium.

    摘要翻译: 公开了一种用于浑浊介质的光学成像的方法和装置。 该方法包括在混浊介质中以参考血氧饱和度(SaO2)从混浊介质发出的光的参考光强度的参考测量值,以及用于根据测量的参考光强度重建浊度介质的参考图像的参考成像步骤。 此外,该方法包括在浑浊培养基中以对比血氧饱和度(SaO2)水平从浑浊培养基发出的光的对比度强度的对比度测量,以及用于从所测量的重量中重建浑浊培养基的对比度图像的对比度成像步骤 对比强度。 对比图像与混浊介质的参考图像之间进行比较。

    Method and Device for Imaging an Interior of a Turbid Medium
    94.
    发明申请
    Method and Device for Imaging an Interior of a Turbid Medium 有权
    用于成像浊度介质内部的方法和装置

    公开(公告)号:US20080290256A1

    公开(公告)日:2008-11-27

    申请号:US12094634

    申请日:2006-11-21

    IPC分类号: H03F3/08

    CPC分类号: A61B5/4312 A61B5/0091

    摘要: The invention relates to a method and device (1) for imaging an interior of a turbid medium (55). A turbid medium (55) inside a measurement volume (15) is irradiated from a plurality of source positions (25a) with light from a light source (5), and light emanating from the measurement volume (15) is detected from a plurality of detection positions (25b). An image of the interior of the turbid medium (55) is reconstructed from the detected light. In both the method and the device (1), detector signals can be amplified for each source position-detection position pair by a multi-gain amplification unit comprising an amplifier circuit (60). The amplification factor is selected from a number of possible amplification factors based on detected signal strength in the prior art. According to the invention, however, the method and device are adapted such that the amplification factor is selected for at least one source position-detection position pair on the basis of an estimate of expected electrical signal strength.

    摘要翻译: 本发明涉及一种用于对浑浊介质(55)的内部进行成像的方法和装置(1)。 从多个源位置(25a)利用来自光源(5)的光照射测量体积(15)内部的混浊介质(55),并且从测量体积(15)发出的光从多个 检测位置(25b)。 从检测到的光重建混浊介质(55)的内部的图像。 在方法和装置(1)中,通过包括放大器电路(60)的多增益放大单元,可以为每个源位置检测位置对放大检测器信号。 基于现有技术中检测到的信号强度,从多个可能的放大因子中选择放大因子。 然而,根据本发明,所述方法和装置被适配成使得根据预期的电信号强度的估计为至少一个源位置检测位置对选择放大系数。

    Device for Imaging an Interior of a Turbid Medium
    95.
    发明申请
    Device for Imaging an Interior of a Turbid Medium 审中-公开
    用于成像混浊介质内部的装置

    公开(公告)号:US20080285823A1

    公开(公告)日:2008-11-20

    申请号:US12094641

    申请日:2006-11-13

    IPC分类号: G06K9/00

    摘要: The invention relates to a device (1) for imaging an interior of a turbid medium (25). The device (1) may be used to accommodate a turbid medium (25) inside a measurement volume (20) and irradiate the turbid medium (25) with light from a light source (5), after which light emanating from the measurement volume (20) is detected and used to determine an image of the interior of the turbid medium (25). The device (1) is adapted such that additional means are introduced for irradiating the turbid medium (25) with light causing fluorescent emission in a contrast agent present in the turbid medium (25), for detecting the fluorescent emission in at least two spectral regions, and for calculating an image reconstruction for the at least two spectral regions detected. By detecting the fluorescent emission spectroscopically, that is as a function of wavelength, information can be obtained from which the concentration of a predetermined component present inside the turbid medium can be determined.

    摘要翻译: 本发明涉及一种用于对浑浊介质(25)的内部进行成像的装置(1)。 装置(1)可以用于容纳测量体积(20)内部的混浊介质(25),并用来自光源(5)的光照射混浊介质(25),之后从测量体积 20)被检测并用于确定混浊介质(25)内部的图像。 装置(1)适于使得附加装置被引入以用在浑浊介质(25)中存在的造影剂中引起荧光发射的光照射混浊介质,用于检测至少两个光谱区域中的荧光发射 并且用于计算所检测的所述至少两个光谱区域的图像重建。 通过检测荧光发射光谱,即作为波长的函数,可以获得可以确定存在于混浊介质内的预定成分的浓度的信息。

    Method and System for Scanning an Information Carrier Via One-Dimensional Scanning
    96.
    发明申请
    Method and System for Scanning an Information Carrier Via One-Dimensional Scanning 审中-公开
    通过一维扫描扫描信息载体的方法和系统

    公开(公告)号:US20080212430A1

    公开(公告)日:2008-09-04

    申请号:US12089776

    申请日:2006-10-11

    IPC分类号: G11B7/00

    摘要: A system for reading an information carrier having a data layer (101) on which is stored a data set. A probe array generating means (104) generates an array of light spots (102) which is applied to the data layer (101). The resultant output light beams are representative of the binary value of data stored in the data layer (101). Macro-cell scanning is effected in a single dimension by moving the array of light spots (102) relative to the data layer (101) along a path (A,B) which is non-parallel to the axes of the matrix defining the probe array. One-dimensional scanning results in a less complex system.

    摘要翻译: 一种用于读取具有数据层(101)的信息载体的系统,其上存储有数据集。 探针阵列产生装置(104)产生施加到数据层(101)的光点阵列(102)。 所得到的输出光束代表存储在数据层(101)中的数据的二进制值。 通过沿着不平行于限定探针的矩阵的轴的路径(A,B)相对于数据层(101)移动光点阵列(102),在单个维度中实现宏小区扫描 数组。 一维扫描导致较不复杂的系统。

    Grazing incidence mirror, lithographic apparatus including a grazing incidence mirror, method for providing a grazing incidence mirror, method for enhancing EUV reflection of a grazing incidence mirror, device manufacturing method and device manufactured thereby
    98.
    发明授权
    Grazing incidence mirror, lithographic apparatus including a grazing incidence mirror, method for providing a grazing incidence mirror, method for enhancing EUV reflection of a grazing incidence mirror, device manufacturing method and device manufactured thereby 有权
    掠入射镜,包括掠入射镜的光刻设备,用于提供掠入射镜的方法,用于增强掠射入射镜的EUV反射的方法,由此制造的器件制造方法和器件

    公开(公告)号:US07235801B2

    公开(公告)日:2007-06-26

    申请号:US10860656

    申请日:2004-06-04

    IPC分类号: G21K5/00 G02B5/28

    摘要: A grazing incidence mirror includes a mirror substrate and a mirror surface layer, the mirror surface layer including a first layer and a second layer, the first layer being positioned between the mirror substrate and the second layer. The first layer includes a material selected from the group of Mo, Nb and combinations thereof, and the second layer includes a material selected from the group of B, C, B4C, SiC and combinations thereof. Such a grazing incidence mirror can be used in lithographic apparatus and in device manufacturing methods and provides a reflectivity that may be larger than state of the art grazing incidence mirrors based on Ru.

    摘要翻译: 掠射入射镜包括镜面基板和镜面层,镜面层包括第一层和第二层,第一层位于镜面基板和第二层之间。 第一层包括选自Mo,Nb及其组合的材料,第二层包括选自B,C,B 4 C,SiC及其组合的材料。 这样的掠入射镜可以用于光刻设备和器件制造方法中,并提供可能比现有技术的基于Ru的掠入射镜更大的反射率。