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116 条记录 (耗时 0.036 秒)

    Hierarchical rate limiting of control packets
    91.
    发明授权
    Hierarchical rate limiting of control packets 有权
    控制包的分级速率限制

    公开(公告)号：US08249088B2

    公开(公告)日：2012-08-21

    申请号：US12432383

    申请日：2009-04-29

    申请人： Anubhav Gupta ,  Arunkumar M. Desigan ,  Arun Sharma

    发明人： Anubhav Gupta ,  Arunkumar M. Desigan ,  Arun Sharma

    IPC分类号： H04L12/28

    CPC分类号： H04L63/1458 ,  G06F21/552 ,  G06F2221/2145 ,  G06F2221/2151 ,  H04L12/4641 ,  H04L47/25 ,  H04L47/323 ,  H04L63/0254

    摘要： Line cards receive control packets and perform a hierarchical rate limiting on those control packets. A set of identifier keys are extracted from the control packets and the protocol of those control packets are determined. At a first level, the control packets are rate limited per unique set of identifier keys per protocol. Those packets which fail the first rate limiting level are dropped. Those packets which pass the first rate limiting level are rate limited at a second level per protocol type. Those packets which fail the second level rate limiting are dropped while those packets which pass the second level rate limiting are sent to the control card for further processing.

    摘要翻译： 线卡接收控制包，并对这些控制包执行分级速率限制。 从控制包中提取一组标识符密钥，并确定这些控制包的协议。 在第一级，每个协议的唯一集合的标识符密钥对控制分组进行速率限制。 那些失败第一速率限制级别的数据包被丢弃。 通过第一速率限制级别的那些分组的速率限制在每个协议类型的第二级别。 丢失第二级速率限制失败的分组，而通过第二级速率限制的分组被发送到控制卡进行进一步处理。

    Method of ensuring the integrity of TLB entries after changing the translation mode of a virtualized operating system without requiring a flush of the TLB
    92.
    发明授权
    Method of ensuring the integrity of TLB entries after changing the translation mode of a virtualized operating system without requiring a flush of the TLB 有权
    改变虚拟化操作系统的翻译模式，而不需要刷新TLB，确保TLB条目完整性的方法

    公开(公告)号：US07823151B2

    公开(公告)日：2010-10-26

    申请号：US11153573

    申请日：2005-06-15

    申请人： Rohit Seth ,  Arun Sharma

    发明人： Rohit Seth ,  Arun Sharma

    IPC分类号： G06F9/455 ,  G06F9/46

    CPC分类号： G06F12/1054 ,  G06F12/0888

    摘要： Systems and methods are disclosed to support partial physical addressing modes on a virtual machine. An example method disclosed herein identifies a change of a first translation mode to a second translation mode on a host hardware platform, the host hardware platform including a processor, the processor further including region registers; identifies an address as cacheable or non-cacheable; saves contents of the region registers for the first translation mode to processor memory; updates content of the region registers corresponding to the second translation mode; identifies a change of the second translation mode to the first translation mode; and populates the region registers with the contents of the saved region registers corresponding to the first translation mode.

    摘要翻译： 公开了系统和方法来支持虚拟机上的部分物理寻址模式。 本文公开的示例性方法将主机硬件平台上的第一翻译模式改变为第二翻译模式，所述主机硬件平台包括处理器，所述处理器还包括区域寄存器; 将地址标识为可缓存或不可缓存; 将第一翻译模式的区域寄存器的内容保存到处理器存储器; 更新对应于第二翻译模式的区域寄存器的内容; 将第二翻译模式的改变识别为第一翻译模式; 并使用对应于第一翻译模式的保存的区域寄存器的内容填充区域寄存器。

    Human hematopoietic growth regulatory gene product
    93.
    发明授权
    Human hematopoietic growth regulatory gene product 失效
    人造血生长调节基因产物

    公开(公告)号：US07612167B2

    公开(公告)日：2009-11-03

    申请号：US11141072

    申请日：2005-05-31

    申请人： Arun Sharma ,  Ronald Hoffman

    发明人： Arun Sharma ,  Ronald Hoffman

    IPC分类号： C07K14/435 ,  C07K14/47 ,  C07K14/475 ,  C12N5/00 ,  C12N5/06 ,  C12N5/08

    CPC分类号： C12N5/0647 ,  C07K14/4702 ,  C12N2501/125 ,  C12N2501/23 ,  C12N2501/40 ,  C12N2510/00

    摘要： The present invention relates to novel human hiwi protein and genes that encode such proteins. The invention is directed toward the isolation and characterization of human hiwi proteins. The invention specifically provides isolated complementary DNA copies of mRNA corresponding to a human hiwi gene. Also provided are recombinant expression constructs capable of expressing the human hiwi gene of the invention in cultures of transformed prokaryotic and eukaryotic cells, as well as such cultures of transformed cells that synthesize the human hiwi proteins encoded therein. The invention also provides methods for isolating human hematopoietic stem cells.

    摘要翻译： 本发明涉及编码这种蛋白质的新型人类hiwi蛋白质和基因。 本发明涉及人类hiwi蛋白的分离和表征。 本发明特别提供了与人hiwi基因相对应的mRNA的分离的互补DNA拷贝。 还提供了能够在转化的原核和真核细胞的培养物中表达本发明的人hiwi基因以及合成其中编码的人hiwi蛋白的转化细胞的这种培养物的重组表达构建体。 本发明还提供了分离人类造血干细胞的方法。

    Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbon1]-5-oxazolidine carboxylic acids
    94.
    发明申请
    Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbon1]-5-oxazolidine carboxylic acids 失效
    使用3 - [（取代-2-三烷基甲硅烷基）乙氧基羰基] -5-恶唑烷羧酸制备抗癌紫杉烷的方法

    公开(公告)号：US20080064887A1

    公开(公告)日：2008-03-13

    申请号：US11812180

    申请日：2007-06-15

    申请人： Arun Sharma ,  Subrata Sarkar ,  Jyan Mahanty

    发明人： Arun Sharma ,  Subrata Sarkar ,  Jyan Mahanty

    IPC分类号： C07D305/04

    CPC分类号： C07D263/04 ,  C07D305/14 ,  C07D413/12

    摘要： This invention relates to a process for preparation of taxanes comprising subjecting 7,10-diprotected intermediates 7-O-(2-haloacyl)baccatin III 6c or 7,10-O-di-(2-haloacyl)-10-deacetylbaccatin III 6b to a step of coupling with (4S,5R)-3-[(2-alkyl/aryl-2-trialkylsilyl)ethoxy-carbonyl]-4-aryl-2-substituted-1,3-oxazolidine-5-carboxylic acid 1 in the presence of a condensation agent, an activating agent and an aromatic hydrocarbon to obtain 7-O-[2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3(2-unsubstituted/substituted-2-trialkylsilyl)-ethoxycarbonyl-1,3-oxazolidinyl-5-carbonyl]baccatin III 7a or 7,10-di-O [2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-unsubstituted/substituted-2-trialkylsilyl)ethoxy-carbonyl-1, 3-oxazolidinyl-5-carbonyl]-10-deacetylbaccatin III 7b; treating the coupled products 7-O-[2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-substituted-2-trialkylsilyl)ethoxy-carbonyl-1, 3-oxazolidinyl-5-carbonyl]baccatin III 7a or 7,10-di-O-[2[(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-substituted-2-trialkylsilyl)ethoxycarbonyl-1, 3-oxazolidinyl-5-carbonyl-10-deacetylbaccatin III 7b with tetraalkylammonium halide in a haloalkane to obtain free amine of structure 8; treating free amine 8 with acid chloride or acid anhydride in the presence of a base in a heterogeneous phase to obtain the intermediates of structure 9; subjecting the intermediates of compound 9 to the deprotection of 2-haloacyl group under mild alkaline condition at −20 to +40° C. for 6-24 h in the presence of ammonia or aliphatic amines or aromatic amines or their combination to obtain paclitaxel or docetaxel.

    摘要翻译： 本发明涉及一种制备紫杉烷的方法，包括将7,10-双保护的中间体7-O-（2-卤代酰基）浆果赤霉素III 6c或7,10-O-二（2-卤代酰基）-10-脱乙酰基浆果赤霉素III 6b （4S，5R）-3 - [（2-烷基/芳基-2-三烷基甲硅烷基）乙氧基 - 羰基] -4-芳基-2-取代-1,3-唑烷-5-羧酸1 在缩合剂，活化剂和芳烃存在下，得到7-O- [2-（卤代酰基）] - 13 - [（4S，5R）-4-芳基-2-取代-3（2- 未取代的/取代的2-三烷基甲硅烷基） - 乙氧基羰基-1,3-恶唑烷基-5-羰基]浆果赤霉素III 7a或7,10-二-O- [2-（卤代酰基）] - 13 - [（4S，5R）-4 （2-未取代的/取代的2-三烷基甲硅烷基）乙氧基羰基-1,3-恶唑烷基-5-羰基] -10-脱乙酰基浆果赤霉素III 7b; 处理偶联产物7-O- [2-（卤代酰基）] - 13 - [（4S，5R）-4-芳基-2-取代-3-（2-取代-2-三烷基甲硅烷基）乙氧羰基-1 3-恶唑烷基-5-羰基]浆果赤霉素III 7a或7,10-二-O- [2 [（卤代酰基）] - 13 - [（4S，5R）-4-芳基-2-取代-3- 取代的2-三烷基甲硅烷基）乙氧基羰基-1,3-恶唑烷基-5-羰基-10-脱乙酰基浆果赤霉素III 7b与四烷基卤化铵在卤代烷烃中反应，得到结构8的游离胺; 在碱存在下用酰氯或酸酐处理游离胺8，得到结构9的中间体; 使化合物9的中间体在温和碱性条件下在-20至+ 40℃下在氨或脂族胺或芳族胺或其组合的存在下将2-卤代酰基脱保护6-24小时，得到紫杉醇或 多西紫杉醇

    Distillation tower baffle
    95.
    发明申请
    Distillation tower baffle 有权
    蒸馏塔挡板

    公开(公告)号：US20070175746A1

    公开(公告)日：2007-08-02

    申请号：US11698099

    申请日：2007-01-26

    申请人： Arun Sharma ,  Theodore Sideropoulos ,  Rutton Patel ,  Brian Albert ,  Alvin Chen

    发明人： Arun Sharma ,  Theodore Sideropoulos ,  Rutton Patel ,  Brian Albert ,  Alvin Chen

    IPC分类号： B01D3/14

    CPC分类号： B01D45/08 ,  B01D1/305 ,  B01D3/32 ,  Y10S159/16

    摘要： An improved de-entrainment device for use in distillation towers, especially vacuum distillation towers used for fractionating petroleum atmospheric resids comprises a baffle which is to be located in the portion of the tower below the feed zone and at the top of the flash zone. The baffle is in the form of an apertured plate above the stripping zone and in its preferred form comprises number of radial fins or blades, resembling a static fan with openings between the fins to permit vapors from the lower portions of the tower to pass upwards through the baffle with a minimal pressure drop. The fins of the baffle are preferably oriented at an angle between 30° and 60° away from the incoming feed so that the incoming feed stream skims over the top edges of the fins.

    摘要翻译： 用于蒸馏塔，特别是用于分馏石油常压渣油的真空蒸馏塔的改进的去夹装置包括挡板，其位于进料区下方和闪蒸区顶部的塔的部分。 挡板是在汽提区上方的多孔板的形式，并且其优选形式包括数量的径向翅片或叶片，类似于在翅片之间具有开口的静态风扇，以允许来自塔的下部的蒸汽向上通过 挡板具有最小的压降。 挡板的翅片优选地与进料相比以30°和60°之间的角度取向，使得进入的进料流在翅片的顶部边缘上滑动。

    Adaptive vibration control for servo systems in data storage devices
    99.
    发明授权
    Adaptive vibration control for servo systems in data storage devices 失效
    数据存储设备伺服系统的自适应振动控制

    公开(公告)号：US06549349B2

    公开(公告)日：2003-04-15

    申请号：US09955391

    申请日：2001-09-18

    申请人： Sri Muthuthamby Sri-Jayantha ,  Arun Sharma ,  Hien Phu Dang ,  Naoyuki Kagami ,  Yuzo Nakagawa ,  Akira Tokizono ,  Isao Yoneda

    发明人： Sri Muthuthamby Sri-Jayantha ,  Arun Sharma ,  Hien Phu Dang ,  Naoyuki Kagami ,  Yuzo Nakagawa ,  Akira Tokizono ,  Isao Yoneda

    IPC分类号： G11B2736

    CPC分类号： G11B21/106 ,  G11B5/59611

    摘要： Methods and systems for detecting and correcting for undesirable vibrations impacting the servo systems in data storage devices. A detection technique is provided wherein a detection filter is configured to scan a position signal of the servo system across a range of frequencies, and, at each respective scanned frequency, record an amplitude associated therewith. The recorded amplitudes are examined to determine whether any exceed a threshold, thereby locating a peak frequency of the vibration. Using the detected peak frequency of the vibration, a corrective filter is configured to operate about the peak frequency of vibration, thereby reducing its impact on the position signal in the servo system. Optimum detection and correction filter structures are disclosed, as are techniques for addressing filter state vectors as initial conditions as the corrective filters are repeatedly engaged during successive settle-out and track follow cycles (between seeks), as are continuous adaptation techniques for changing vibration environments.

    摘要翻译： 用于检测和校正影响数据存储设备中的伺服系统的不期望的振动的方法和系统。 提供了一种检测技术，其中检测滤波器被配置为扫描频率范围内的伺服系统的位置信号，并且在每个相应的扫描频率处记录与之相关联的振幅。 检查记录的振幅以确定是否有超过阈值，从而定位振动的峰值频率。 使用检测到的振动峰值频率，校正滤波器被配置为围绕振动的峰值频率运行，从而减小其对伺服系统中位置信号的影响。 公开了最佳检测和校正滤波器结构，作为用于将滤波器状态向量寻址作为初始条件的技术，校正滤波器在连续的稳定和跟踪周期（寻找之间）期间重复接合），以及用于改变振动环境的连续自适应技术 。

    Increased and randomized output sampling to reduce positioning noise in a data storage system
    100.
    发明授权
    Increased and randomized output sampling to reduce positioning noise in a data storage system 失效
    增加和随机输出采样，以减少数据存储系统中的定位噪声

    公开(公告)号：US06181507B2

    公开(公告)日：2001-01-30

    申请号：US08692164

    申请日：1996-08-05

    申请人： Nobuyuki Kitazaki ,  Kiyoshi Satoh ,  Arun Sharma ,  Sri Muthuthamby Sri-Jayantha ,  Isao Yoneda

    发明人： Nobuyuki Kitazaki ,  Kiyoshi Satoh ,  Arun Sharma ,  Sri Muthuthamby Sri-Jayantha ,  Isao Yoneda

    IPC分类号： G11B5596

    CPC分类号： G11B5/59605 ,  G11B5/59627 ,  G11B5/5965

    摘要： A method and system for reducing positioning noise in a data storage system are provided. An access device is positioned over a data storage medium using a stream of bursts stored on the medium. The bursts are sensed at a frequency determined by the rate at which the medium is moved relative to a sensing device. Output positioning values are provided to position the access device at a frequency higher than the frequency at which the positioning bursts are sensed, and/or at random times. The random times may be calculated as random advances or delays from time points occurring at a fixed frequency.

    摘要翻译： 提供了一种用于降低数据存储系统中的定位噪声的方法和系统。 访问设备使用存储在介质上的突发流来定位在数据存储介质上。 以由介质相对于感测装置移动的速率确定的频率感测脉冲串。 提供输出定位值以将访问设备定位在高于感测定位脉冲串的频率的频率处和/或随机时间。 随机时间可以被计算为在固定频率发生的时间点的随机前进或延迟。