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91.
公开(公告)号:US20050100936A1
公开(公告)日:2005-05-12
申请号:US10927669
申请日:2004-08-26
申请人: Verena Lutz , Friedemann Krause , Manuela Poignee , Thomas Walter , Baerbel Porstmann , Martin Werner , Silke Lassmann
发明人: Verena Lutz , Friedemann Krause , Manuela Poignee , Thomas Walter , Baerbel Porstmann , Martin Werner , Silke Lassmann
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158
摘要: The present invention is directed to a method for determining whether a patient suffering from cancer will be responsive to a treatment with a 5-Fluoro-Uracil and/or 5-Fluoro-Uracil analogs. Specifically, the invention relates to methods of determining the expression levels of certain mRNAs to determine responsiveness to drug treatment.
摘要翻译: 本发明涉及一种用于确定患有癌症的患者是否对5-氟尿嘧啶和/或5-氟尿嘧啶类似物的治疗有反应的方法。 具体地,本发明涉及确定某些mRNA的表达水平以确定对药物治疗的反应性的方法。
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公开(公告)号:US06870047B2
公开(公告)日:2005-03-22
申请号:US09756743
申请日:2001-01-10
申请人: Jörg Kleiber , Thomas Walter , Herbert Harttig , Christoph Lesniak , Martin Mennig , Michael Riedling , Helmut Schmidt
发明人: Jörg Kleiber , Thomas Walter , Herbert Harttig , Christoph Lesniak , Martin Mennig , Michael Riedling , Helmut Schmidt
IPC分类号: G01N33/552 , B01J20/28 , B03C20060101 , B03C1/01 , C07H20060101 , C07H1/08 , C07H21/00 , C12N20060101 , C12N15/09 , C12N15/10 , C12N15/11 , C12Q20060101 , C12Q1/68 , G01N33/553 , H01F1/00 , H01F1/11 , H01F1/36 , C12N15/00 , C12N13/00 , C12P19/34
CPC分类号: C03C3/111 , B03C1/01 , B82Y25/00 , C03C3/078 , C03C3/083 , C03C3/085 , C03C3/087 , C03C3/089 , C03C3/091 , C03C3/102 , C03C3/105 , C03C3/108 , C07H21/00 , C12N15/1013 , C12Q1/6804 , C12Q1/6806 , C12Q1/6834 , H01F1/0063 , H01F1/112 , H01F1/36 , Y10S428/90 , Y10S435/814 , Y10T428/2996
摘要: Magnetic particles are prepared containing a magnetic core coated with a glass layer having a substantially pore-free class surface or having pores with a diameter offices than 10 nm. The particles are used for separating biological material such as nucleic acids. A preferred process of preparing the particles is by forming a mixture of magnetic cores with a sol formed from an alcohol and a metal alkoxide, spray-drying the mixture to coat the cores with a layer of gelled sol, and heating the coated cores to obtain the magnetic glass particles. Preferably, the particles have an average particle size of less than 100 μm. The magnetic core may be a composite material containing a mica core and magnetite particles immobilized on the mica core, and the glass layer may contain boron oxide. Magnetic core materials include magnetite (Fe3O4) and Fe2O3.
摘要翻译: 制备磁性颗粒,其包含涂覆有具有基本上无孔的等级表面或具有直径为10nm以上的孔的玻璃层的磁芯。 颗粒用于分离生物材料如核酸。 制备颗粒的优选方法是通过用由醇和金属醇盐形成的溶胶形成磁芯的混合物,喷雾干燥混合物以用一层凝胶溶胶涂覆芯,并加热涂覆的芯以获得 磁性玻璃颗粒。 优选地,颗粒的平均粒度小于100μm。 磁芯可以是包含固定在云母芯上的云母芯和磁铁矿颗粒的复合材料,并且玻璃层可以含有氧化硼。 磁芯材料包括磁铁矿(Fe3O4)和Fe2O3。
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公开(公告)号:US06322654B1
公开(公告)日:2001-11-27
申请号:US09417391
申请日:1999-10-13
申请人: Thomas Walter , Maximilian Zaher
发明人: Thomas Walter , Maximilian Zaher
IPC分类号: B44C1175
CPC分类号: B05D1/20 , B41M5/025 , B44C1/1745 , B44C1/1758 , Y10S428/914
摘要: A method is disclosed for transferring a colored decoration to an article by applying the decoration onto a first support, transferring the printed decoration onto a second support and then transferring the decoration to the article. To transfer the decoration, it is floated upon a liquid and the article is pressed against the floating decoration.
摘要翻译: 公开了一种通过将装饰施加到第一支撑件上将彩色装饰转移到物品的方法,将印刷的装饰转印到第二支撑件上,然后将装饰物转印到制品上。 为了转移装饰,将其漂浮在液体上,并将物品压在浮动装饰上。
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公开(公告)号:US6105745A
公开(公告)日:2000-08-22
申请号:US106634
申请日:1998-06-29
申请人: Ulrich Husse , Kurt Lindner , Karl Muller , Reiner Voss , Thomas Walter
发明人: Ulrich Husse , Kurt Lindner , Karl Muller , Reiner Voss , Thomas Walter
CPC分类号: F16D23/12 , F16D2300/12
摘要: A disengagement mechanism for a friction clutch which is to be arranged between an internal combustion engine and a transmission flanged to the internal combustion engine by a casing includes a guide pipe fastenable in the casing. A release bearing element is guided radially at the outer circumference of the guide pipe so as to be axially movable thereon. The disengagement mechanism also includes a clutch lever which is to be articulated at the casing for transmitting clutch actuating forces to the release bearing element. At least the guide pipe, the release bearing, and the clutch lever are held together to form a constructional unit prior to their arrangement between the internal combustion engine and the transmission by movement limiting device, thereby facilitating the assembly of the disengagement mechanism. In the operation-ready, installed state, the movement limiting devices influences the movability of the disengagement mechanism.
摘要翻译: 一种用于摩擦离合器的分离机构,该摩擦离合器设置在内燃机与通过壳体引导到内燃机之间的传动装置之间,包括可在壳体内固定的导向管。 释放轴承元件在引导管的外周径向引导以便在其上轴向移动。 分离机构还包括离合器杆,该离合器杆将在壳体处铰接,以将离合器致动力传递到释放轴承元件。 在通过移动限制装置在内燃机和变速器之间的布置之前,至少导向管,释放轴承和离合器杆保持在一起以形成结构单元,从而便于分离机构的组装。 在操作就绪的安装状态下,移动限制装置影响分离机构的可移动性。
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