-
公开(公告)号：US20190100789A1
公开(公告)日：2019-04-04
申请号：US16084941
申请日：2016-09-09
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Siavosh Rezvan Behbahani
IPC: C12Q1/689 , G16H50/20 , G16H50/50 , C12Q1/6806 , C12Q1/6809 , G06F17/15 , G06F17/18
Abstract: Methods, compositions, and systems are provided for detecting one or more effects of antibiotic usage for an infectious disease or other health condition on the microbiome of an individual, monitoring such effects, and/or determining, displaying, or promoting a therapy for such an effect. Methods, compositions, and systems are also provided for generating and comparing microbiome composition and/or functional diversity datasets. Methods, compositions, and systems are also provided for generating a characterization model for antibiotic usage.
-
公开(公告)号：US20190080046A1
公开(公告)日：2019-03-14
申请号：US16132195
申请日：2018-09-14
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Patricio Lagos , Ricardo Castro , Paz Tapia
Abstract: Embodiments of a method and/or system, such as for characterizing at least one microorganism-related condition, can include: determining a set of associations (e.g., positive associations such as positive correlations, negative associations such as negative correlations, non-associations such as no correlation or minimal correlation, etc.) between a set of microorganism taxa and at least one microorganism-related condition; determining a set of reference features (e.g., reference abundance ranges, etc.) for the set of microorganism taxa; and determining one or more significance index metrics based on the set of associations and the set of reference features.
-
公开(公告)号：US20190078085A1
公开(公告)日：2019-03-14
申请号：US16125619
申请日：2018-09-07
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Eduardo Morales , Rodrigo Ortiz , Nicolas Ordenes , Juan Jimenez , Cristian Bravo , Natalia Scioscia , Eduardo Olivares , Luis Leon , Paulo Covarrubias , Felipe Sepulveda , Felipe Melis
IPC: C12N15/10 , C12N15/11 , C12Q1/6806 , C12Q1/6811 , C12Q1/686 , C12Q1/6876 , C12N15/66 , C12Q1/6855 , C12Q1/6869
Abstract: Embodiments of a method and/or system, such as for preparation of a normalized library for sequencing such as next-generation sequencing, can include one or more of: generating one or more normalized amplicon libraries; generating one or more normalized microbial community-associated libraries; and/or generating one or more normalized combined sequence libraries associated with amplicon-associated sequencing and microbial community-associated sequencing.
-
94.发明申请公开(公告)号：US20190050525A1
公开(公告)日：2019-02-14
申请号：US16103830
申请日：2018-08-14
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Valeria Marquez , Ingrid Araya , Melissa Alegria , Mario Saavedra , Luis Gomez , Janyra Espinoza , Javier Gimpel , Eduardo Morales , Rodrigo Ortiz
Abstract: Embodiments of a method and/or system can include administering, to a patient with one or more conditions associated with at least one of TMA, TMAO, and/or derivatives thereof, a therapeutically effective amount of a compound for affecting inhibiting one or more CutC enzymes and/or CntA enzymes associated with microorganisms from at least one taxon from a set of microorganism taxa.
-
公开(公告)号：US20190019575A1
公开(公告)日：2019-01-17
申请号：US16124108
申请日：2018-09-06
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Juan Ugalde , Patricia Vera-Wolf , Sandro Valenzuela
Abstract: Embodiments of a method and/or system (e.g., for nasal-related characterization) can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a nasal-related characterization process, and/or determining one or more therapies, such as for one or more nasal-related conditions.
-
Patent Agency Ranking
96.发明申请公开(公告)号：US20180137931A1
公开(公告)日：2018-05-17
申请号：US15848824
申请日：2017-12-20
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G16H10/40 , C12Q1/6883 , C12Q2600/112 , G01N2800/044 , G01N2800/32 , G06F19/3418 , G16B40/00 , G16B50/00 , G16H50/20 , H01L27/3211 , H01L27/322 , H01L27/3272 , H01L51/0097 , H01L51/5234 , H01L51/5265 , H01L51/5281 , H01L51/5284 , H01L2251/5338 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating a cardiovascular disease condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cardiovascular disease condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cardiovascular disease condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
-
公开(公告)号：US20180137239A1
公开(公告)日：2018-05-17
申请号：US15707907
申请日：2017-09-18
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Laurens Kraal , Francisco Ossandon , Juan Pablo Cardenas , Elisabeth Bik , Audrey Goddard
CPC classification number: G16B30/00 , G16B20/00 , G16B40/00 , G16H10/40 , G16H20/60 , G16H50/20 , Y02A90/26
Abstract: Embodiments of a system and method for characterizing a panel of conditions associated with a set of taxa related to microorganisms can include a taxonomic database including reference microbiome features for the set of taxa associated with the panel of conditions; a handling operable to collect a container including biological material from a user, the handling system comprising a sequencer system operable to determine a microorganism sequence dataset; and a panel characterization system operable to: determine user microbiome features for the set of taxa for the user based on the microorganism sequence dataset, generate a comparison between the user microbiome features and the reference microbiome features, and determine a panel characterization for the panel of conditions for the user based on the comparison; and a treatment system operable to promote a therapy for a condition of the panel of conditions based on the panel characterization.
-
98.发明申请公开(公告)号：US20180122514A1
公开(公告)日：2018-05-03
申请号：US15849110
申请日：2017-12-20
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G16H50/20 , C12Q1/6874 , G06F19/3418 , G16B40/00 , G16B50/00 , G16H10/40 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
-
公开(公告)号：US20180122511A1
公开(公告)日：2018-05-03
申请号：US15845190
申请日：2017-12-18
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Catalina Valdivia , Rodrigo Ortiz , Inti Pedroso , Victoria Dumas , Paz Tapia , Eduardo Morales
IPC: G06F19/28
Abstract: Embodiments of a method and/or system for characterizing a microorganism-related condition (e.g., human behavior condition, disease-related condition, etc.) for a user can include one or more of: generating a microbiome dataset for each of an aggregate set of biological samples associated with a population of subjects, based on sample processing of the biological samples; processing a supplementary dataset associated with one or more microorganism-related conditions for the set of users; and performing a microorganism-related characterization (e.g., human behavior characterization, disease-related characterization, etc.) process for the one or more microorganism-related conditions, based on the supplementary dataset and/or microbiome features extracted from the microbiome dataset.
-
100.发明申请公开(公告)号：US20180070825A1
公开(公告)日：2018-03-15
申请号：US15815365
申请日：2017-11-16
Applicant: uBiome, Inc
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: A61B5/0022 , A61B5/4836 , C12Q1/689 , C12Q2600/112 , G06F19/3418 , G16B40/00 , G16B50/00 , G16H50/20 , G16H50/80 , Y02A90/24 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
-
-
-
-
-
-
-
-
-
Search Results
161
records
(took 0.037 seconds)
