公开(公告)号：US20230159924A1

公开(公告)日：2023-05-25

申请号：US17905442

申请日：2021-03-02

Applicant: MITSUBISHI TANABE PHARMA CORPORATION ,  KYOTO UNIVERSITY ,  OSAKA UNIVERSITY ,  NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION

Inventor： Jun KOTERA ,  Koh ONO ,  Takahiro HORIE ,  Tomohiro YAMASAKI ,  Satoshi KOYAMA ,  Satoshi OBIKA ,  Yuya KASAHARA

IPC: C12N15/113 ,  A61P9/00

CPC classification number: C12N15/113 ,  A61P9/00 ,  C12N2310/11 ,  C12N2310/32 ,  C12N2310/3341 ,  C12N2310/315

Abstract: A prophylactic or therapeutic agent for an aneurysm comprising a miR-33b inhibiting substance, preferably an antisense oligonucleotide against miR-33b, as an active ingredient.

公开(公告)号：US11652194B2

公开(公告)日：2023-05-16

申请号：US17305808

申请日：2021-07-14

Applicant: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEM ,  OSAKA UNIVERSITY ,  NICHIA CORPORATION

Inventor： Tsukasa Torimoto ,  Tatsuya Kameyama ,  Marino Kishi ,  Chie Miyamae ,  Susumu Kuwabata ,  Taro Uematsu ,  Daisuke Oyamatsu ,  Kenta Niki

IPC: H01L33/50 ,  C09K11/62 ,  H01L33/00 ,  H01L33/06

CPC classification number: H01L33/502 ,  C09K11/62 ,  H01L33/005 ,  H01L33/06 ,  H01L33/507

Abstract: Semiconductor nanoparticles including Ag, In, Ga, and S are provided. In the semiconductor nanoparticles, a ratio of a number of Ga atoms to a total number of In and Ga atoms is 0.95 or less. The semiconductor nanoparticles emit light having an emission peak with a wavelength in a range of from 500 nm to less than 590 nm, and a half bandwidth of 70 nm or less, and have an average particle diameter of 10 nm or less.

公开(公告)号：US20230146210A1

公开(公告)日：2023-05-11

申请号：US17518212

申请日：2021-11-03

Applicant: MITSUBISHI TANABE PHARMA CORPORATION ,  OSAKA UNIVERSITY

Inventor： Maiko HAMADA ,  Yuki ARAI ,  Shuhei YAMAKOSHI ,  Hiroko WADA ,  Kazufumi OTSUKI ,  Hiroaki SHITAMA ,  Nobuyuki TAKAKURA

IPC: C07F9/568 ,  C07F9/58 ,  A61K45/06

CPC classification number: C07F9/568 ,  C07F9/58 ,  A61K45/06

Abstract: The present invention aims to provide a compound acting as a specific agonist for LPA4 receptors, and a pharmaceutical composition containing the compound. The present invention relates to a novel lysophosphatidic acid derivative having an agonistic action on LPA4 receptors and useful for the prophylaxis and/or treatment of diseases associated with angiogenesis abnormalities involving LPA4 receptors, diseases associated with vascular disorders, or the symptoms associated therewith, and a pharmaceutical composition containing the derivative.

公开(公告)号：US20230141614A1

公开(公告)日：2023-05-11

申请号：US17913066

申请日：2021-02-12

Applicant: OSAKA UNIVERSITY

Inventor： Shuko TAKEDA ,  Ryuichi MORISHITA

IPC: A61B5/00 ,  A61B3/113

CPC classification number: A61B5/4088 ,  A61B3/113 ,  A61B5/7445

Abstract: A cognitive impairment diagnostic device includes: an obtainer that obtains a distribution map representing a distribution of gaze points of a subject on a movie for cognitive assessment; and a diagnoser. The movie for cognitive assessment includes, in time order: a first movie including a first region including an image for encoding displayed in a visually enhanced manner, and a plurality of second regions including normal images displayed without being enhanced; and an assessment movie including a third region including an assessment image similar to the image for encoding and displayed at a same position as the image for encoding without being visually enhanced, and the second regions. The diagnoser calculates, in a distribution map on the assessment movie, a percentage of fixation duration for which the third region is focused on, and makes diagnosis of suspected memory impairment when the percentage of fixation duration is lower than a threshold.

公开(公告)号：US20230136323A1

公开(公告)日：2023-05-04

申请号：US17910629

申请日：2021-03-18

Applicant: KUNIMINE INDUSTRIES CO., LTD. ,  OSAKA UNIVERSITY

Inventor： Munehiro KUBOTA ,  Kazutake TSUJIKAWA

IPC: C12M3/00 ,  C12N5/07

Abstract: A spheroid formation promoter, including: inorganic particles having adsorbability as an active ingredient; and a method of promoting spheroid formation, including the step of: mixing a dispersion liquid of the spheroid formation promoter and a cell suspension to obtain a mixture in which the inorganic particles having adsorbability contained in the spheroid formation promoter are dispersed, and culturing a cell contained in the obtained mixture to promote spheroid formation.

公开(公告)号：US11635096B2

公开(公告)日：2023-04-25

申请号：US17547788

申请日：2021-12-10

Applicant: ADVANCED TELECOMMUNICATIONS RESEARCH INSTITUTE INTERNATIONAL ,  OSAKA UNIVERSITY

Inventor： Tomoyuki Noda ,  Yoshihiro Nakata ,  Hiroshi Ishiguro ,  Jun Morimoto

IPC: F15B15/08 ,  F15B15/14 ,  F15B21/08 ,  H02K33/16 ,  H02K41/03 ,  H02K7/20 ,  B25J19/00 ,  B25J11/00 ,  A61F2/70 ,  A61H3/00 ,  B25J9/00 ,  F15B15/12 ,  F15B15/20 ,  H02K41/035

Abstract: [Object] To provide a compact, high-output actuator device allowing force control.
[Solution] An actuator device 1000 includes an electromagnetic coil member 110 provided over a prescribed width on an outer circumference of a cylinder 100, and a movable element 200 slidable as a piston in the cylinder 100. The movable element 200 has a magnetic member 202, and is moved relatively by excitation of the electromagnetic coil member 110. Fluid is supplied to first and second chambers 106a and 106b such that when the movable element 200 is to be moved relatively, the movable element 200 is driven in the same direction.

公开(公告)号：US11634890B2

公开(公告)日：2023-04-25

申请号：US16315737

申请日：2017-08-24

Applicant: Komatsu Ltd. ,  Osaka University

Inventor： Takanobu Tanimoto ,  Yu Nanri ,  Yukinori Matsumura ,  Kazuhisa Takahama

IPC: E02F9/26 ,  B60K35/00 ,  B60R1/00 ,  E02F3/32

Abstract: An image display system for a work machine including working equipment having a working tool and a turning body to which the working equipment is attached, includes: a position detector detecting at least one of an attitude and a position of the working equipment; a distance detector obtaining information on a distance from the work machine to a work target; and a processing device that generates, by using information on a position of the working tool obtained by the position detector and information on a position of the work target obtained from the information on the distance obtained by the distance detector, a first image including a portion corresponding to a part of the working tool and extending along a turning direction of the turning body, on the work target opposed to the working tool, and displays the first image on the display device.

公开(公告)号：US20230113556A1

公开(公告)日：2023-04-13

申请号：US17907323

申请日：2021-03-26

Applicant: NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER ,  OSAKA UNIVERSITY

Inventor： Mariko SHIBA ,  Tsuyoshi YAMAMOTO ,  Fumito WADA ,  Tadayuki KOBAYASHI ,  Keisuke TACHIBANA ,  Satoshi OBIKA

IPC: C12N15/113 ,  A61P3/06

Abstract: The present invention provides an antisense oligomer having the base sequence depicted in SEQ ID NO: 26, an antisense oligomer having a base sequence resulting from substitution, deletion, insertion, or addition of 1 to 6 bases in the base sequence depicted in SEQ ID NO: 26, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable hydrate thereof, an oligonucleotide conjugate in which the antisense oligomer is bound with a molecule capable of binding to an asialoglycoprotein receptor, and a pharmaceutical composition containing the same.

公开(公告)号：US11627485B2

公开(公告)日：2023-04-11

申请号：US17230202

申请日：2021-04-14

Applicant: NEC CORPORATION ,  OSAKA UNIVERSITY ,  THE DOSHISHA

Inventor： Kazushi Muraoka ,  Naoto Ishii ,  Takumi Takahashi ,  Shinsuke Ibi

IPC: H04W28/02 ,  H04L1/00 ,  H04W72/04 ,  H04W72/08

Abstract: A computer system includes at least one memory and at least one processor coupled to the at least one memory and configured to execute one or more sets of instructions. The one or more sets of instructions, when executed by the at least one processor, cause the computer system to provide virtualized radio access network functions including executing a BP algorithm and provide controller functions including adjusting the total number of iterations of the BP algorithm depending on available computing resources of the computer system.

公开(公告)号：US11623975B2

公开(公告)日：2023-04-11

申请号：US16481117

申请日：2018-01-26

Applicant: OSAKA UNIVERSITY ,  DAIKIN INDUSTRIES, LTD.

Inventor： Akihiro Oshima ,  Kazuyuki Satoh ,  Mitsuhiro Usugaya ,  Yoshikage Ohmukai ,  Yuko Shiotani

IPC: C08F277/00 ,  B29C35/08 ,  B29K23/00

Abstract: A molding material including a resin material that has a graft chain containing constituent units derived from a fluorine-containing compound and a non-fluorinated compound. The graft chain thereof may be formed, for example, using ionizing radiation.