公开(公告)号：US20230032072A1

公开(公告)日：2023-02-02

申请号：US17774745

申请日：2020-11-06

Applicant: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY

Inventor： Chul Hong OH ,  Yoon Hyeok KANG ,  Eun Young JO ,  Do Hyung KANG ,  Young Deuk LEE ,  Duck Hee JANG ,  Ye Hui GANG ,  Tae Yang EOM ,  Sachithra Amarin HETTIARACHCHI

IPC: C07K14/485 ,  C07K14/245 ,  C12N9/24 ,  A61K8/64 ,  A61Q19/00 ,  A61P17/02

Abstract: The present invention relates to a novel human epidermal growth factor (hEGF)-trigger factor (TF) fusion protein and a use thereof. More particularly, the human epidermal growth factor (hEGF)-trigger factor (TF) fusion protein of the present invention has fused therein: a signal peptide of a Bacillus subtilis-derived xylanase; a human epidermal growth factor (hEGF); and an Escherichia coli-derived trigger factor (TF). Therefore, the present invention not only enhances the water solubility and expression rate of a target protein, but also notably enhances useful effects such as the effects of increasing skin cell growth and healing a wound, and thus may be widely used in various industries as an active ingredient for a functional cosmetic composition and a pharmaceutical composition.

公开(公告)号：US20220404507A1

公开(公告)日：2022-12-22

申请号：US17731964

申请日：2022-04-28

Applicant: Korea Institute of Ocean Science & Technology

Inventor： Moonjin Lee ,  Yongmyung Kim ,  Tae-Sung Kim

IPC: G01S19/13 ,  G01R31/3835 ,  B63B79/15 ,  B63B22/00 ,  B63H1/14

Abstract: This application relates to an apparatus for tracking location using a control platform of a small buoy for simulating marine pollutants, in which at least one small observation buoy floats on the ocean, and a relay buoy collects location information from the observation buoy and provides the collected location information to a weather information management server. The apparatus may include at least one observation buoy and a relay buoy, the observation buoy including a GPS receiver which receives a signal transmitted from a GPS satellite and generate location information. The apparatus may also include a communicator performing wireless transmission and reception of signals with the relay buoy, and a power source providing driving power to the GPS receiver and the communicator. The relay buoy may receive location information from the at least one observation buoy and provide the received location information to a weather information management server.

公开(公告)号：US11526981B2

公开(公告)日：2022-12-13

申请号：US16761753

申请日：2018-11-06

Applicant: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SE-JONG CAMPUS

Inventor： Sang-Woo Oh ,  Moon-Jin Lee ,  Sungkyu Seo ,  Dongmin Seo ,  Sanghoon Shin

IPC: G06T7/00 ,  C12Q1/02

Abstract: The present invention relates to an ecotoxicity evaluation analysis device installed with a microalgae image analysis program therein for analyzing the microalgae 1 and evaluating and analyzing ecotoxicity, the device comprising: a complementary metal oxide semiconductor unit 10 having an arranging part 15 on the top for positioning the microalgae 1 and installed with a microalgae image analysis program therein for photographing a microscopic image and a shadow image of the microalgae 1 and analyzing the images; and a light emitting diode unit 20 for irradiating a light source to the microalgae 1 located in the arranging part 15 of the complementary metal oxide semiconductor unit 10.

公开(公告)号：US20220213463A1

公开(公告)日：2022-07-07

申请号：US17292967

申请日：2018-11-28

Applicant: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY

Inventor： Jung-Hyun LEE ,  Jae Kyu LIM ,  Hyun Sook LEE ,  Sung Gyun KANG ,  Kae Kyoung KWON ,  Yun Jae KIM ,  Ji-in YANG

IPC: C12N9/96 ,  C12N9/02 ,  C12N15/52 ,  C12P7/40

Abstract: The present invention relates to an Fe—S fusion protein acting as an electron transport chain, a novel carbon monoxide:formate oxidoreductase (CFOR) including the Fe—S fusion protein, novel Thermococcus strain BCF12 transformed with CFOR, and the use thereof. According to the present invention, two different enzymes may be physically linked directly to each other through the Fe—S fusion protein of the present invention, and thus electrons generated from any one enzyme may be transported directly to another enzyme through the Fe—S cluster of the Fe—S fusion protein. Accordingly, a reaction that produces a target substance with high efficiency by directly supplying electrons necessary for the production of the target substance is possible without leakage of electrons generated in any one enzyme. In addition, the present invention has an advantage in that the overall enzyme reaction rate and yield can be dramatically improved using a new electron transport reaction. Furthermore, it is possible to ensure the stability of each enzyme by allowing the enzymes to exist in a physically fixed state in cells.

公开(公告)号：US20220112128A1

公开(公告)日：2022-04-14

申请号：US17467028

申请日：2021-09-03

Applicant: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY

Inventor： Seoung Ik CHOI ,  Min Ook KIM ,  Taek Hee HAN ,  Jun Kil PARK ,  Hye Min HONG ,  Sung Won KIM ,  Sang Min PARK

IPC: C04B18/20 ,  D02G3/44

Abstract: This application relates to a cement mortar composition reinforced with a shredded waste fishing net and a method of manufacturing the cement mortar composition. In one aspect, the cement mortar composition includes cement mortar including cement, fine aggregate, and water and 0.5 to 2.0 parts by weight of a fibrous reinforcing material based on 100 parts by weight of the cement mortar. The fibrous reinforcing material may be manufactured by shredding a knotless fishing net and being formed of a single yarn that has a length of 3 mm to 60 mm and a diameter of 0.1 mm to 1 mm. The cement mortar composition that has improved crack resistance and tensile strength and in which an environmentally friendly and inexpensive reinforcing material obtained by shredding a waste fishing net at a random length instead of existing highly-expensive reinforcing material is included may be realized.

公开(公告)号：US20210332063A1

公开(公告)日：2021-10-28

申请号：US17268896

申请日：2018-08-17

Applicant: Korea Institute of Ocean Science & Technology

Inventor： Jong Seok Lee ,  Dan Bi Sung ,  Bo Hyun Mun ,  Sol Park ,  Hyi Seung Lee ,  Yeon Ju Lee ,  Ji Hoon Lee ,  Hee Jae Shin

IPC: C07D495/04 ,  B01J23/52 ,  C09K11/06 ,  G01N31/22 ,  G01N33/58

Abstract: Disclosed are a method for synthesizing a thieno[3,2-b]pyridine-5(4H)-one derivative by using a gold catalyst and a use of the derivative compound, wherein the novel thieno[3,2-b]pyridine-5(4H)-one derivative of the present disclosure, which is a compound synthesized using gold as a catalyst, has fluorescence characteristics with a wide range of emission wavelengths and thus can be helpfully used in various industrial fields, such as physics, chemistry, and biomedicine research.

公开(公告)号：US20210323841A1

公开(公告)日：2021-10-21

申请号：US17221681

申请日：2021-04-02

Applicant: Korea Institute of Ocean Science & Technology

Inventor： Kyoungrean KIM

IPC: C02F1/42 ,  C02F1/52 ,  C02F1/44 ,  B01D63/06 ,  B01D69/04 ,  B01D65/02

Abstract: A system for remedying deep-sea mine tailings includes a reaction basin in which the solid-liquid ratio of deep-sea mine tailings is adjusted and into which aluminum sulfate is injected as an additive for extraction of heavy metals from the deep-sea mine tailings.

公开(公告)号：US20210145721A1

公开(公告)日：2021-05-20

申请号：US16634046

申请日：2017-09-26

Applicant: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY

Inventor： Heejae SHIN ,  Gambang PIL ,  Hyiseung LEE ,  Jongseok LEE ,  Yeonju LEE ,  Jihoon LEE

IPC: A61K8/49 ,  C07D309/36 ,  A61Q19/08 ,  A61Q19/02 ,  A23L33/00 ,  A23L33/10

Abstract: The present invention relates to a novel compound represented by following formula 2 produced by means of marine-derived fungus Penicillium sp. and a composition for improving skin wrinkles, enhancing elasticity and skin whitening using excellent collagen synthesis promoting activity and melanin production inhibitory activity of the novel compound. In formula 2, R1 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R1 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R2 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R3 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R4 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms.

公开(公告)号：US10784971B2

公开(公告)日：2020-09-22

申请号：US16072643

申请日：2018-01-25

Applicant: Korea Institute of Ocean Science & Technology

Inventor： Young Chol Choi ,  A Ra Cho ,  Yong Kon Lim

IPC: G01V1/38 ,  G01S1/72 ,  H04B13/02 ,  H04W72/00 ,  H04W40/24

Abstract: The present invention relates to a method of scheduling for an underwater wireless mobile network. Particularly, the present invention relates to a method of scheduling for an underwater wireless mobile network, whereby the method may consider a scheduling method that does not cause collision at a specific time domain, and improve network efficiency by receiving in a sink node a packet in a packet train form in consideration with a transfer velocity of a sound wave and a packet length rather than performing orthogonalization to avoid transmission time overlap at a specific time.

公开(公告)号：US20200294263A1

公开(公告)日：2020-09-17

申请号：US15781563

申请日：2016-10-24

Applicant: Korea Institute of Ocean Science & Technology

Inventor： Deuk Jae CHO ,  Moon Jin LEE

IPC: G06T7/70 ,  G06T7/60 ,  G01S13/72

Abstract: The present invention relates to a method and an apparatus for continuously detecting a hazardous and noxious substance from multiple satellites, and specifically, provides a method and an apparatus for continuously detecting a hazardous and noxious substance from multiple satellites, the method and apparatus: receiving a multi-satellite image which is photographed by a multi-satellite comprising a satellite having an imaging radar (SAR), a satellite having an infrared sensor, and a satellite having an electronic optical sensor; acquiring a reference image, of the satellite having the SAR, including a ground control point of an observed region; extracting a corresponding point between the reference image and the multi-satellite image; implementing the image matching and geometric correction for the multi-satellite image by using the extracted corresponding point; confirming at least one among the brightness value of pixels of the SAR satellite image, the temperature value of pixels of the infrared satellite image or the color value of pixels of the optical satellite image which are included in the corrected multi-satellite image so as to detect the hazardous and noxious substance, and determine the flow information, thereby detecting continuously and stably the hazardous and noxious substance.