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    Detecting stannous ions
    108.
    发明授权
    Detecting stannous ions 有权
    检测亚锡离子

    公开(公告)号：US09354219B1

    公开(公告)日：2016-05-31

    申请号：US14580497

    申请日：2014-12-23

    Applicant: Colgate-Palmolive Company

    Inventor： Stanislav Jaracz ,  Michael Prencipe

    IPC: G01N33/20 ,  G01N21/78 ,  G01N21/77 ,  G01N21/79 ,  A61Q11/00

    CPC classification number: G01N33/20 ,  A61Q11/00 ,  G01N21/77 ,  G01N21/78 ,  G01N21/79

    Abstract: A method of detecting stannous ions that includes providing a zincon-containing indicator having a color, contacting the indicator with a sample, and detecting any resulting change in the color of the indicator, wherein a change in the color of the indicator from the color to colorless indicates that stannous ions are present in the sample. The method is useful for the analysis of oral care compositions. Also provided is the use of zinc on as an indicator for detecting stannous ions.

    Abstract translation: 一种检测亚锡离子的方法，其包括提供具有颜色的含有蕴含锌的指示剂，使所述指示剂与样品接触，并检测所述指示剂的颜色的任何变化，其中所述指示剂的颜色从所述颜色变为 无色表示样品中存在亚锡离子。 该方法对口腔护理组合物的分析是有用的。 还提供了使用锌作为检测亚锡离子的指示剂。

    Tooth whitening dental tray and method of use
    109.
    发明授权
    Tooth whitening dental tray and method of use 有权

    公开(公告)号：US09320581B2

    公开(公告)日：2016-04-26

    申请号：US13897817

    申请日：2013-05-20

    Applicant: COLGATE-PALMOLIVE COMPANY

    Inventor： Michael Prencipe ,  Suman K. Chopra ,  Michael Collins

    IPC: A61K6/00 ,  A61K8/22 ,  A61K8/25 ,  A61Q11/00 ,  A61C19/06 ,  A61K8/81 ,  A61K8/891 ,  A61K8/18

    CPC classification number: A61C19/066 ,  A61K8/18 ,  A61K8/22 ,  A61K8/8176 ,  A61K8/891 ,  A61Q11/00

    Abstract: A dental tray with a hydrophobic tooth whitening formulation where the tooth whitening formulation is substantially non-water soluble, and a method of using this dental tray to whiten the teeth. The tooth whitening formulation is primarily comprised of a hydrophobic polymer and a peroxide or a peroxide yielding compound. Preferably the hydrophobic polymer is the condensation product of a silicone resin and an organosiloxane. The dental tray is formed to encompass the front and the rear surfaces of the teeth. The dental tray is comprised of a thermoplastic or thermoset polymer. The teeth whitening formulation is placed into the dental tray and the tray placed against the teeth to be whitened. This is for a sufficient period of time to at least partially whiten teeth. This can be a period of time from about 0.5 hour to 2 hours or more. The substantially non-aqueous tooth whitening formulation is effective over a longer period of time since it is not significantly diluted or removed from the dental tray during the treatment time.

    Stannous salt and sodium tripolyphosphate oral care compositions and methods
    110.
    发明授权
    Stannous salt and sodium tripolyphosphate oral care compositions and methods 有权
    亚锡盐和三聚磷酸钠口腔护理组合物和方法

    公开(公告)号：US09265710B2

    公开(公告)日：2016-02-23

    申请号：US14560168

    申请日：2014-12-04

    Applicant: Colgate-Palmolive Company

    Inventor： James R. Brown ,  Linh Fruge ,  Tao Xu ,  Michael Prencipe

    IPC: A61K8/00 ,  A61K8/24 ,  A61K8/36 ,  A61Q11/00 ,  A61K8/69 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/21 ,  A61K8/81 ,  A61K8/55

    CPC classification number: A61K8/21 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/25 ,  A61K8/55 ,  A61K8/69 ,  A61K8/8164 ,  A61K2800/28 ,  A61K2800/591 ,  A61Q11/00

    Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1 of the compositions. Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) prior to dental care usage.

    Abstract translation: 提供含有亚锡盐和三聚磷酸钠的口腔护理组合物，其中三聚磷酸三钠离子中间体包含少于约1种组合物。 可以加入焦磷酸四钠，甲基乙烯基醚 - 马来酸酐共聚物和/或二氧化硅口腔抛光剂以获得更高的效力。 在单相共混物中，口腔护理组合物可以有效地限制为包含小于约10％的水。 在双相共混物中，在牙齿保健使用之前，可以从双室存储管（每个相位由独立的室提供）产生具有第一相中的亚锡盐和第二相中的三聚磷酸钠的混合物。

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