公开(公告)号：US08362215B2

公开(公告)日：2013-01-29

申请号：US12770674

申请日：2010-04-29

申请人： Bruce Keyt ,  Lawrence M. Kauvar ,  Ellen J. Collarini ,  Orit Foord ,  Gizette Sperinde ,  Marjan Fatholahi ,  Hung Nguyen

发明人： Bruce Keyt ,  Lawrence M. Kauvar ,  Ellen J. Collarini ,  Orit Foord ,  Gizette Sperinde ,  Marjan Fatholahi ,  Hung Nguyen

IPC分类号： C07K16/00 ,  A61K39/395

CPC分类号： C07K16/2863 ,  C07K16/22 ,  C07K16/30 ,  C07K16/32 ,  C07K16/40 ,  C07K2317/32 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/76

摘要： Antibodies which specifically bind heregulin-coupled HER3, at a site distinct from the heregulin binding site, are described. These antibodies are particularly useful in treating cancer.

摘要翻译： 描述了在不同于调节蛋白结合位点的位点上特异性结合随机结合的HER3的抗体。 这些抗体特别可用于治疗癌症。

公开(公告)号：US08226710B2

公开(公告)日：2012-07-24

申请号：US13072194

申请日：2011-03-25

申请人： Than Nguyen ,  Hung Nguyen ,  Mykim Nguyen ,  Stanley Komatsu ,  Robrecht Michiels

发明人： Than Nguyen ,  Hung Nguyen ,  Mykim Nguyen ,  Stanley Komatsu ,  Robrecht Michiels

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0039 ,  Y10S623/90

摘要： A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

摘要翻译： 提供了一种心脏瓣膜假体，其具有支撑包括裙部和多个附着小叶的阀体的自膨胀多层框架。 框架在允许经皮腔内递送的收缩递送构型和具有不对称沙漏形状的扩张部署构型之间转变。 阀体裙部和小叶被构造成使得可以选择接合中心以减小施加到阀的连合处的水平力，并且有效地分布和传递沿着传单和框架的力。 或者，阀体可以用作可手术植入的置换瓣膜假体。

公开(公告)号：US20110172765A1

公开(公告)日：2011-07-14

申请号：US13072194

申请日：2011-03-25

申请人： Than Nguyen ,  Hung Nguyen ,  Mykim Nguyen ,  Stanley Komatsu ,  Robrecht Michiels

发明人： Than Nguyen ,  Hung Nguyen ,  Mykim Nguyen ,  Stanley Komatsu ,  Robrecht Michiels

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0039 ,  Y10S623/90

摘要： A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

摘要翻译： 提供了一种心脏瓣膜假体，其具有支撑包括裙部和多个附着小叶的阀体的自膨胀多层框架。 框架在允许经皮腔内递送的收缩递送构型和具有不对称沙漏形状的扩张部署构型之间转变。 阀体裙部和小叶被构造成使得可以选择接合中心以减小施加到阀的连合处的水平力，并且有效地分布和传递沿着传单和框架的力。 或者，阀体可以用作可手术植入的置换瓣膜假体。

公开(公告)号：US07914569B2

公开(公告)日：2011-03-29

申请号：US11128826

申请日：2005-05-13

申请人： Than Nguyen ,  Hung Nguyen ,  Mykim Nguyen ,  Stanley Komatsu ,  Robrecht Michiels

发明人： Than Nguyen ,  Hung Nguyen ,  Mykim Nguyen ,  Stanley Komatsu ,  Robrecht Michiels

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0039 ,  Y10S623/90

摘要： A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

摘要翻译： 提供了一种心脏瓣膜假体，其具有支撑包括裙部和多个附着小叶的阀体的自膨胀多层框架。 框架在允许经皮腔内递送的收缩递送构型和具有不对称沙漏形状的扩张部署构型之间转变。 阀体裙部和小叶被构造成使得可以选择接合中心以减小施加到阀的连合处的水平力，并且有效地分布和传递沿着传单和框架的力。 或者，阀体可以用作可手术植入的置换瓣膜假体。

公开(公告)号：US20100216437A1

公开(公告)日：2010-08-26

申请号：US12680839

申请日：2007-10-26

申请人： Jean Chouraqui ,  Hung Nguyen

发明人： Jean Chouraqui ,  Hung Nguyen

IPC分类号： H04M3/42

CPC分类号： H04N21/439 ,  G10L19/00 ,  H04N1/00281 ,  H04N1/00307 ,  H04N1/00312 ,  H04N21/233 ,  H04N21/2368 ,  H04N21/41407 ,  H04N21/4341 ,  H04N21/643 ,  H04N2201/0025 ,  H04N2201/0084

摘要： There are provided methods and systems for transferring multimedia content using an existing digital sound transfer protocol. A system for processing multimedia content for transfer over one or more networks includes a transformation device (211) and a reconstruction device (251). The transformation device (211) is for transforming a multimedia file into a sound file for subsequent transfer over the one or more networks using an existing digital sound transfer protocol. The multimedia file represents the multimedia content. The reconstruction device (251) is for reconstructing the multimedia content from the sound file, after the sound file has been transferred.

摘要翻译： 提供了使用现有数字声音传输协议传送多媒体内容的方法和系统。 用于处理通过一个或多个网络传送的多媒体内容的系统包括变换设备（211）和重建设备（251）。 变换装置（211）用于将多媒体文件变换成声音文件，以便使用现有的数字声音传送协议通过一个或多个网络进行后续传送。 多媒体文件表示多媒体内容。 重建装置（251）用于在传送声音文件之后从声音文件重建多媒体内容。

公开(公告)号：US20080313433A1

公开(公告)日：2008-12-18

申请号：US12196102

申请日：2008-08-21

申请人： Hung Nguyen ,  Shannon Wichman

发明人： Hung Nguyen ,  Shannon Wichman

IPC分类号： G06F9/38

CPC分类号： G06F9/3853 ,  G06F9/30072

摘要： A processor is disclosed including several features allowing the processor to simultaneously execute instructions of multiple conditional execution instruction groups. Each conditional execution instruction group includes a conditional execution instruction and a code block specified by the conditional execution instruction. In one embodiment, the processor includes multiple registers for storing marking data pertaining to a number of instructions in each of multiple execution pipeline stages. In another embodiment, the processor includes write enable logic and an execution unit. The write enable logic produces write enable signals dependent upon received attributes, and the execution unit saves results of instructions of conditional execution instruction groups dependent upon the write enable signals.

摘要翻译： 公开了一种处理器，其包括允许处理器同时执行多个条件执行指令组的指令的若干特征。 每个条件执行指令组包括条件执行指令和由条件执行指令指定的代码块。 在一个实施例中，处理器包括多个寄存器，用于存储与多个执行流水线级中的每一个中的多个指令有关的标记数据。 在另一个实施例中，处理器包括写使能逻辑和执行单元。 写使能逻辑根据接收的属性产生写使能信号，执行单元根据写使能信号保存条件执行指令组的指令结果。

公开(公告)号：US20080309275A1

公开(公告)日：2008-12-18

申请号：US11820070

申请日：2007-06-18

申请人： Hung Nguyen ,  Mayer Robert

发明人： Hung Nguyen ,  Mayer Robert

IPC分类号： B25J9/18

CPC分类号： E01F13/06 ,  E05F5/12 ,  E05Y2400/41 ,  E05Y2800/21

摘要： A control system and method for ensuring proper closure of a dual swing gate. The control system employs position sensors for monitoring the position of each gate arm. A “differential position” is maintained between the arms during closing to ensure proper sequencing. The control system regulates the speed of the master arm and the slave arm to ensure that the differential position is maintained throughout the closure process.

摘要翻译： 一种用于确保双摆门正确关闭的控制系统和方法。 控制系统采用位置传感器来监控每个门臂的位置。 在关闭期间在手臂之间保持“差异位置”，以确保顺序顺利。 控制系统调节主臂和从动臂的速度，以确保在整个关闭过程中保持差速位置。

公开(公告)号：US07450986B2

公开(公告)日：2008-11-11

申请号：US10469814

申请日：2002-02-28

申请人： Hung Nguyen ,  Nejhdeh Ghevondian

发明人： Hung Nguyen ,  Nejhdeh Ghevondian

IPC分类号： A61B5/04

CPC分类号： G06F19/3481 ,  A61B5/00 ,  A61B5/024 ,  A61B5/0402 ,  A61B5/0531 ,  A61B5/14532 ,  A61B5/7267 ,  G06F19/00 ,  G16H40/63

摘要： The invention relates to the modelling and design of early warning systems for detecting medical conditions using physiological responses. The device comprises sensors for monitoring physiological parameters such as skin impedance, heart rate, and QT interval of a patient, means for establishing when those parameters change, the rate of change of the parameters, and a neural network processor for processing the information obtained by the sensors. The neural network processor is programmed with a fast learning algorithm. When the neural network establishes that a physiological condition is present in the patient an alarm signal will be generated. The invention extends to a method of non-invasive monitoring of a person using a neural network programmed with a fast learning algorithm. A non-invasive hypoglycaemia monitor is specifically described.

摘要翻译： 本发明涉及使用生理反应来检测医学状况的预警系统的建模和设计。 该装置包括用于监测生理参数的传感器，例如患者的皮肤阻抗，心率和QT间隔，用于建立何时这些参数改变，参数变化率的装置，以及用于处理由 传感器。 神经网络处理器用快速学习算法编程。 当神经网络确定患者中存在生理状况时，将产生报警信号。 本发明延伸到使用使用快速学习算法编程的神经网络的人的非侵入性监测的方法。 具体描述非侵入性低血糖监测器。

公开(公告)号：US07397978B1

公开(公告)日：2008-07-08

申请号：US11180990

申请日：2005-07-13

申请人： Hung Nguyen

发明人： Hung Nguyen

IPC分类号： G02B6/12

CPC分类号： G02B6/12004

摘要： An apparatus is disclosed that includes a carrier structure and an optical coupling arrangement. The carrier structure is made of a silicon material and allows for the packaging and integrating of microphotonic devices onto a single chip. The optical coupling mechanism enables laser light to be coupled into and out of a microphotonic resonant disk integrated on the carrier. The carrier provides first, second and third cavities that are dimensioned so as to accommodate the insertion and snug fitting of the microphotonic resonant disk and first and second prisms that are implemented by the optical coupling arrangement to accommodate the laser coupling.

摘要翻译： 公开了一种包括载体结构和光耦合装置的装置。 载体结构由硅材料制成，并允许将微电子器件封装并集成到单个芯片上。 光学耦合机构使得激光能够耦合入和集成在载体上的微孔谐振盘。 载体提供第一，第二和第三空腔，其尺寸被设计成适应由光耦合装置实现以适应激光耦合的微孔谐振盘和第一和第二棱镜的插入和贴合。

公开(公告)号：US20080099279A1

公开(公告)日：2008-05-01

申请号：US11590040

申请日：2006-10-31

申请人： Donald Griswold ,  Hung Nguyen

发明人： Donald Griswold ,  Hung Nguyen

IPC分类号： E06C5/32

CPC分类号： E06C7/14 ,  E06C1/39

摘要： A storage device is particularly suitable for mounting to aluminum or fiberglass step ladders. A mounting assembly on one side of a planar member includes a track into which one leg of the ladder is fitted, and resilient clips that snap over the other leg of the ladder. A support member rests on a cross bar of the ladder. Storage bins are provided on the second side of the planar member. The storage bins may include covers that can be latched into the open or closed position. The storage device is able to remain in place on a step ladder even when the step ladder is folded up.

摘要翻译： 存储装置特别适合于安装到铝或玻璃纤维梯级。 在平面构件的一侧上的安装组件包括一个轨道，梯子的一条腿被装配到该轨道中，弹性夹子卡在梯子的另一条腿上。 支撑构件位于梯子的横杆上。 存储箱设置在平面构件的第二侧上。 存储箱可以包括可以锁定到打开或关闭位置的盖。 即使梯子折叠，存储装置也能够在梯级梯上保持就位。