摘要:
The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
摘要:
This invention relates to substantially anhydrous warming, non-toxic and nonirritating lubricating compositions containing polyhydric alcohols and an insulating agent. The invention also relates to methods of using such compositions for lubrication, administration of active ingredients and for preventing or treating dysmenorrhea.
摘要:
A method is provided for segmenting an image of interest of a left ventricle. The method includes determining a myocardium contour according to a graph cut of candidate endocardium contours, and a spline fitting to candidate epicardium contours in the absence of shape propagation. The method further includes applying a plurality of shape constraints to candidate endocardium contours and candidate epicardium contours to determine the myocardium contour, wherein a template is determined by shape propagation of a plurality of images in a sequence including the image of interest in the presence of shape propagation.
摘要:
The present invention relates to compounds of Formula I, II or Ill, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: wherein W is a substituted or unsubstituted heterocyclic ring system. The compounds inhibit serine protease activity, particularly the activity of hepatitis c virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis c virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
摘要:
A pneumatic demultiplexer that allows a person with a disability to control multiple assistive technology devices by the use of a single sip-and-puff tube. The devices to be controlled are operated by a single pneumatic or electrical switch input. The pneumatic demultiplexer is under the control of a microprocessor. In a scan stage the user selects the target device via scrolling LED indicators. When a specific device is chosen, the corresponding solenoid valve is activated to connect the input sip-and-puff port to the pneumatic output port. In the activation stage, the input sip-and-puff tube controls the target device directly via the pneumatic demultiplexer. The microprocessor monitors the line activity via a sip-or-puff switch. A watchdog timer is implemented by the microprocessor. After there is a lack of activity for preprogrammed time period, the system switches from the activation stage back to the scan stage.
摘要:
Methods and devices to improve the efficiency of uplink scheduling among user equipment (UEs) are disclosed. In one aspect, a base station with a scheduler utilizes a notional or holding “LCG,” in addition to LCGs that correspond to an LCG to which a UE maps one or more logical channels. This notional LCG is a dedicated LCG for maintaining temporary priority information based on the receipt of a scheduling request (SR) from the UE.
摘要:
The present disclosure concerns a method, uplink traffic control device and computer program product. The method comprises determining that predictive scheduling is to be applied for the mobile station. Thereafter an uplink transmission scheme is determined for the predictive scheduling. Thereafter periodic messages comprising uplink transmission grants, according to the uplink transmission scheme, are sent to the mobile station, said messages further comprising a request for a downlink channel quality indicator, CQI, report.
摘要:
A method (200) for a controlling node of a cell (110) in a cellular system, the method comprising (205) the use of Radio Link Control Acknowledged Mode, RLC AM, and scheduling (210) transmissions in the downlink and uplink directions to/from User Equipments, UEs (115, 120, 125), in the cell (110). The scheduling comprises taking into account a priority which each UE has for its transmissions, and counting (215) the number of scheduled transmissions for a UE in a first of said directions since its latest scheduled transmission in the other of said directions. If (220) the count has reached a predetermined value, the priority of the UE in the other of said directions is increased (225), and when (230) the UE has been scheduled for a transmission in said other direction, the counting in said first direction is restarted (235) from an initial value.
摘要:
Methods and devices to improve the efficiency of uplink scheduling among user equipment (UEs) are disclosed. In one aspect, a base station with a scheduler utilizes a notional or holding “LCG,” in addition to LCGs that correspond to an LCG to which a UE maps one or more logical channels. This notional LCG is a dedicated LCG for maintaining temporary priority information based on the receipt of a scheduling request (SR) from the UE.
摘要:
A method and an apparatus are disclosed for extending the service life of a battery source by fully utilizing the energy in batteries and/or providing higher energy reserve using multiple batteries. The invention has economical and environmental benefits by reducing waste in batteries in addition to offering convenience and ease of maintenance in battery use. It also benefits the design of devices when replacing batteries is either difficult or impossible. A universal battery bank consists of an ensemble of possibly heterogeneous batteries all connected in series to provide a usable operational energy source. To exploit this power supply that may vary over a wide voltage range, electronics are designed to monitor the individual batteries, guard against excessive voltage and current, and provide constant current sources and/or constant voltage sources for various appliances.