公开(公告)号：US07576239B2

公开(公告)日：2009-08-18

申请号：US12008728

申请日：2008-01-14

Applicant: Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

Inventor： Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

IPC: C07C233/05 ,  C07D213/02 ,  A61K31/44

CPC classification number: C07D213/64 ,  C07C255/60 ,  C07C275/24 ,  C07C2601/04

Abstract: Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.

Abstract translation: 结构式（I）的新型化合物是大麻素-1（CB1）受体的拮抗剂和/或反向激动剂，可用于治疗，预防和抑制由CB1受体介导的疾病。 本发明的化合物可用作治疗精神病，记忆缺陷，认知障碍，偏头痛，神经病，包括多发性硬化和神经 - 巴利综合征的神经炎症性疾病以及病毒性脑炎的炎症性后遗症，脑血管 事故和头部创伤，焦虑症，压力，癫痫，帕金森病，运动障碍和精神分裂症。 这些化合物还可用于治疗药物滥用障碍，治疗肥胖或进食障碍，以及治疗哮喘，便秘，慢性肠假性梗阻和肝硬化。

公开(公告)号：US20080194645A1

公开(公告)日：2008-08-14

申请号：US12008728

申请日：2008-01-14

Applicant: Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

Inventor： Linus S. Lin ,  William K. Hagmann ,  Sanjeev Kumar ,  Wenji Yin ,  George Doss

IPC: A61K31/44 ,  C07D211/86 ,  A61P25/06 ,  A61P25/28

CPC classification number: C07D213/64 ,  C07C255/60 ,  C07C275/24 ,  C07C2601/04

Abstract: Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.

Abstract translation: 结构式（I）的新型化合物是大麻素-1（CB1）受体的拮抗剂和/或反向激动剂，可用于治疗，预防和抑制由CB1受体介导的疾病。 本发明的化合物可用作治疗精神病，记忆缺陷，认知障碍，偏头痛，神经病，包括多发性硬化和神经 - 巴利综合征的神经炎症性疾病以及病毒性脑炎的炎症性后遗症，脑血管 事故和头部创伤，焦虑症，压力，癫痫，帕金森病，运动障碍和精神分裂症。 这些化合物还可用于治疗药物滥用障碍，治疗肥胖或进食障碍，以及治疗哮喘，便秘，慢性肠假性梗阻和肝硬化。

公开(公告)号：USD475445S1

公开(公告)日：2003-06-03

申请号：US29159447

申请日：2002-04-22

Applicant: Sanjeev Kumar

Designer： Sanjeev Kumar

公开(公告)号：US06535961B2

公开(公告)日：2003-03-18

申请号：US08975601

申请日：1997-11-21

Applicant: Christopher B. Wilkerson ,  Sanjeev Kumar

Inventor： Christopher B. Wilkerson ,  Sanjeev Kumar

IPC: G06F1300

CPC classification number: G06F12/0862 ,  Y02D10/13

Abstract: A spatial footprint predictor includes a mechanism to measure spatial footprints of nominating cache-lines and hold the footprints. In some embodiments, the mechanism includes an active macro-block table (AMBT) to measure the spatial footprints and a spatial footprint table (SFT) to hold the spatial footprints. In other embodiments, the mechanism includes a macro-block table (MBT) in which macro-blocks may be active or inactive.

Abstract translation: 空间足迹预测器包括一种测量提名高速缓存行的空间足迹并保持足迹的机制。 在一些实施例中，该机制包括用于测量空间足迹的活动宏块表（AMBT）和用于保持空间足迹的空间足迹表（SFT）。 在其他实施例中，该机制包括宏块表（MBT），其中宏块可以是活动的或不活动的。

公开(公告)号：USD463046S1

公开(公告)日：2002-09-17

申请号：US29149517

申请日：2001-10-11

Applicant: Sanjeev Kumar

Designer： Sanjeev Kumar

公开(公告)号：USD461707S1

公开(公告)日：2002-08-20

申请号：US29141998

申请日：2001-05-16

Applicant: Sanjeev Kumar

Designer： Sanjeev Kumar

公开(公告)号：USD461264S1

公开(公告)日：2002-08-06

申请号：US29149519

申请日：2001-10-10

Applicant: Sanjeev Kumar

Designer： Sanjeev Kumar

公开(公告)号：US06178469B1

公开(公告)日：2001-01-23

申请号：US09107599

申请日：1998-06-30

Applicant: Rick Hennessy ,  David LeClair ,  Sanjeev Kumar ,  John Mallard

Inventor： Rick Hennessy ,  David LeClair ,  Sanjeev Kumar ,  John Mallard

IPC: G06F1314

CPC classification number: G06F13/409

Abstract: A computer has a processor having a bus port operatively connected to a first bus and being operative to selectively access one of a plurality of peripheral devices operatively connected to the bus via at least one of a series of identifiers. The computer also has a peripheral selector for detecting the presence of one or more of the peripheral devices operatively connected to the first and second peripheral ports, for assigning a first of the identifiers to the first peripheral port if one of the peripheral devices is operatively connected to a first peripheral port that is connected to the bus, and for assigning the same first identifier to a second peripheral port that is operatively connected to the bus if the presence of one of the peripheral devices at the first peripheral port is not detected and the presence of one of the peripheral devices at the second peripheral port is detected.

Abstract translation: 计算机具有处理器，其具有可操作地连接到第一总线的总线端口，并且可操作以通过一系列标识符中的至少一个选择性地访问操作地连接到总线的多个外围设备中的一个。 计算机还具有外围选择器，用于检测可操作地连接到第一和第二外围端口的一个或多个外围设备的存在，用于将外部设备中的一个可操作地连接到第一外围端口的第一外围端口 连接到总线的第一外围端口，并且如果没有检测到第一外围端口处的外围设备之一的存在，并且用于将第一标识符分配给可操作地连接到总线的第二外围端口， 检测第二外围端口处的外围设备之一的存在。

公开(公告)号：US6122274A

公开(公告)日：2000-09-19

申请号：US971243

申请日：1997-11-16

Applicant: Sanjeev Kumar

Inventor： Sanjeev Kumar

IPC: H04L12/56

CPC classification number: H04L12/5601 ,  H04L49/255 ,  H04L49/309 ,  H04L2012/5681 ,  H04L49/1546

Abstract: A data packet switch, in general, and an Asynchronous Transfer Mode switch, in particular employing a plurality of physically separate memory modules operates like a single shared memory switch by allowing sharing of all of the memory modules among all of the inputs and outputs of the switch. The disclosed switching apparatus consists of multiple independent stages where different stages of the switch operate without a common centralized controller. The disclosed switch removes performance bottleneck commonly caused by use of a centralized controller in the switching system. Incoming data packets are assigned routing parameters by a parameter assignment circuit based on packets' output destination and current state of the switching system. The routing parameters are then attached as an additional tag to input packets for their propagation through various stages of the switching apparatus. Packets with the attached routing parameters pass through different stages of the switching apparatus and the corresponding switching functions are locally performed by each stage based only on the information available locally. Memory modules along with their controllers use information available locally to perform memory operations and related memory management to realize overall switching function. The switching apparatus and the method facilitates sharing of physically separate memory modules without using a centralized memory controller. The switching apparatus and the method provide higher scalability, simplified circuit design, pipeline processing of data packets and the ability to realize various memory sharing schemes for a plurality memory modules in the switch.

Abstract translation: 通常，数据分组交换机和异步传输模式交换机特别是采用多个物理上分离的存储器模块，如同单个共享存储器开关一样操作，通过允许在所有输入和输出的所有输入和输出之间共享所有存储器模块 开关。 所公开的交换设备由多个独立的阶段组成，其中开关的不同阶段在没有公共集中式控制器的情况下工作。 所公开的交换机消除了通常在交换系统中使用集中控制器造成的性能瓶颈。 基于分组的输出目的地和交换系统的当前状态，通过参数分配电路为入局数据分组分配路由参数。 然后将路由参数附加为附加标签以输入分组，以便它们通过交换设备的各个阶段的传播。 具有附加路由参数的分组通过交换设备的不同阶段，并且相应的切换功能仅基于本地可用的信息由每个级本地执行。 存储器模块及其控制器使用本地可用的信息来执行存储器操作和相关存储器管理以实现整体切换功能。 切换装置和方法便于在不使用集中式存储器控制器的情况下共享物理上分离的存储器模块。 开关装置和方法提供更高的可扩展性，简化的电路设计，数据分组的流水线处理以及为开关中的多个存储器模块实现各种存储器共享方案的能力。

公开(公告)号：US08743114B2

公开(公告)日：2014-06-03

申请号：US12234988

申请日：2008-09-22

Applicant: Changkyu Kim ,  Jatin Chhugani ,  Christian Bienia ,  Daehyun Kim ,  Anthony Ngueyn ,  Sanjeev Kumar

Inventor： Changkyu Kim ,  Jatin Chhugani ,  Christian Bienia ,  Daehyun Kim ,  Anthony Ngueyn ,  Sanjeev Kumar

IPC: G06T15/00 ,  G06T15/40

CPC classification number: G06T15/40

Abstract: Methods and systems to determine view cell occlusion, including to project objects of a 3-dimensional graphics environment to a 2-dimensional image plane with respect to the view point, to reduce sizes of corresponding object images, to generate an occluder map from the reduced-size object images, to compare at least a portion of the object images to the occluder map, and to identify an object as occluded with respect to the view cell when pixel depth values of the object image are greater than corresponding pixel depth values of the occluder map. Methods and systems to reduce an object image size include methods and systems to nullify pixel depth values within a radius of an edge pixel, and to determine the radius as a distance from the edge pixel to a second pixel so that a line between the view point and the second pixel is parallel with one or more of a line and a plane that is tangential to a sphere enclosing the view cell and a point on the object that corresponds to the edge pixel.

Abstract translation: 确定观察细胞闭塞的方法和系统，包括将三维图形环境的对象相对于视点投影到二维图像平面，以减小相应对象图像的大小，从缩小的图像生成闭塞图 将对象图像的尺寸调整为将至少一部分对象图像与遮挡物图进行比较，并且当对象图像的像素深度值大于对象图像的对应像素深度值时，识别相对于视图单元被遮挡的对象 封堵器图。 减少对象图像尺寸的方法和系统包括使边缘像素的半径内的像素深度值无效的方法和系统，并且将半径确定为距离边缘像素到第二像素的距离，使得视点 并且第二像素平行于与包围视图单元的球体相切的线和平面以及与边缘像素对应的物体上的点的一个或多个。