公开(公告)号：USD575130S1

公开(公告)日：2008-08-19

申请号：US29288903

申请日：2007-06-27

申请人： Richard Smith

设计人： Richard Smith

公开(公告)号：US20080035934A1

公开(公告)日：2008-02-14

申请号：US11845805

申请日：2007-08-28

申请人： Scott Sheppard ,  Richard Smith ,  Zoltan Ring

发明人： Scott Sheppard ,  Richard Smith ,  Zoltan Ring

IPC分类号： H01L29/15

CPC分类号： H01L29/66462 ,  H01L21/045 ,  H01L21/3145 ,  H01L21/318 ,  H01L21/3185 ,  H01L29/1608 ,  H01L29/2003 ,  H01L29/24 ,  H01L29/7787

摘要： An improved field effect transistor formed in the Group III nitride material system includes a two part structure in which a chemical vapor deposited passivation layer of silicon nitride encapsulates a previously sputtered-deposited layer of silicon nitride. The sputtered layer provides some of the benefits of passivation and the chemical vapor deposited layer provides an excellent environmental barrier.

摘要翻译： 形成在III族氮化物材料体系中的改进的场效应晶体管包括二部分结构，其中氮化硅的化学气相沉积钝化层封装预先溅射的氮化硅层。 溅射层提供了钝化的一些优点，并且化学气相沉积层提供了优异的环境屏障。

公开(公告)号：US20080026949A1

公开(公告)日：2008-01-31

申请号：US11770074

申请日：2007-06-28

申请人： John Hoidal ,  Mary Scholand ,  Mark Leppert ,  Michael Paul ,  Robert Gritz ,  Joel Pounds ,  Richard Smith

发明人： John Hoidal ,  Mary Scholand ,  Mark Leppert ,  Michael Paul ,  Robert Gritz ,  Joel Pounds ,  Richard Smith

IPC分类号： C40B20/08 ,  C40B30/00 ,  C40B40/10

CPC分类号： C12Q1/6883 ,  G01N33/6848 ,  G01N2800/122 ,  G06F19/18

摘要： Methods are disclosed for generating and isolating an informative content repository of respiratory related biomarkers to accurately determine whether an individual has normal or abnormal pulmonary function. Specifically, methods are directed to determination of whether individuals have chronic obstructive pulmonary disease, and if so, whether the affected individuals experience rapid long decline or slow lung decline as a result of COPD. Also disclosed is an informative content repository of chronic obstructive pulmonary disease biomarkers, which when linked with other informative content provides a powerful tool for diagnosis, study, therapeutic discovery and development, condition management, health maintenance, and linking chronic obstructive pulmonary disease through pattern of life style, environmental exposure, and genetic susceptibility and inheritance. Disclosed herein is a chronic obstructive pulmonary disease biomarker informative content repository comprising at least one COPD biomarker, apparatus and methods to diagnose, assess, address, and ameliorate related conditions.

摘要翻译： 公开了用于产生和分离呼吸相关生物标志物的信息内容库的方法，以准确地确定个体是否具有正常或异常的肺功能。 具体来说，方法是针对确定个体是否患有慢性阻塞性肺疾病，如果是，受影响的个体是否经历COPD的快速长期衰退或肺缓慢缓慢。 还披露了慢性阻塞性肺疾病生物标志物的信息内容库，当与其他信息内容联系时，通过模式的方式为诊断，研究，治疗发现和发展，病症管理，健康维持和慢性阻塞性肺疾病连接提供了强大的工具 生活方式，环境暴露和遗传易感性和遗传。 本文公开了一种慢性阻塞性肺疾病生物标志物信息内容库，其包含至少一种COPD生物标志物，用于诊断，评估，解决和改善相关病症的装置和方法。

公开(公告)号：US07307830B2

公开(公告)日：2007-12-11

申请号：US10766727

申请日：2004-01-27

申请人： Rolland Gallay ,  Daniel Schlunke ,  Richard Smith

发明人： Rolland Gallay ,  Daniel Schlunke ,  Richard Smith

IPC分类号： H01G9/00

CPC分类号： H01G9/08 ,  Y02E60/13

摘要： High reliable energy density capability of double-layer capacitor electrode technology now enables the use of capacitors as supplements to, or replacements for, battery technologies. In one application, when sized to a standard battery form factor, the large end terminal surface areas of such form factors enable that the energy density of capacitors can now be safely used as direct drop-in replacements for batteries.

摘要翻译： 双层电容器电极技术的高可靠能量密度能力现在使电容器成为电池技术的补充或替代品。 在一个应用中，当尺寸适合标准电池形状时，这种形状因子的大端子表面区域使得电容器的能量密度现在可以安全地用作电池的直接插入式替换。

公开(公告)号：US20070236057A1

公开(公告)日：2007-10-11

申请号：US11393451

申请日：2006-03-30

申请人： Richard Smith

发明人： Richard Smith

IPC分类号： A47C31/00

CPC分类号： A47C1/143 ,  A47C3/34 ,  A47C7/62

摘要： A lounge chair assembly having a seat portion, pivotally associated back portion, and further pivotally associated lower leg portion. Each of the seat, back and leg portions includes an outer frame to which is secured an inner user supporting covering. Pairs of spaced apart and downwardly extending legs, either four or six in total, extend from locations associated with the intermediate seat portion. Each of the legs includes an outer fixed portion and a telescopically extending inner portion adjustable to vary a height of the seat portion relative to a supporting ground surface. Recess mounted and outwardly displaceable handle portions are associated with first and second side frame locations of the seat portion to facilitate transport of the same. Also, a side frame mounted and pivotable canister assembly releasably secures a selected item.

摘要翻译： 一种躺椅组件，具有一个座位部分，一个可枢转的相关的后部，另一个可枢转地连接的小腿部分。 座椅，后腿和腿部中的每一个包括外框，外框架固定在内用户支撑罩上。 间隔开的和向下延伸的一对腿，总共四个或六个，从与中间座椅部分相关联的位置延伸。 每个腿包括外部固定部分和可伸缩延伸的内部部分，其可调节以改变座椅部分相对于支撑地面的高度。 嵌入式和可向外移位的手柄部分与座部分的第一和第二侧框架位置相关联，以便于其移动。 此外，侧框架安装和可枢转的罐组件可释放地固定所选择的物品。

公开(公告)号：US20070233394A1

公开(公告)日：2007-10-04

申请号：US11394839

申请日：2006-03-31

申请人： Lars Kangas ,  Richard Smith ,  Konstantinos Petritis

发明人： Lars Kangas ,  Richard Smith ,  Konstantinos Petritis

IPC分类号： G06F19/00 ,  G01N33/50

CPC分类号： G01N33/6848

摘要： A method of predicting whether a peptide present in a biological sample will be detected by analysis with a mass spectrometer. The method uses at least one mass spectrometer to perform repeated analysis of a sample containing peptides from proteins with known amino acids. The method then generates a data set of peptides identified as contained within the sample by the repeated analysis. The method then calculates the probability that a specific peptide in the data set was detected in the repeated analysis. The method then creates a plurality of vectors, where each vector has a plurality of dimensions, and each dimension represents a property of one or more of the amino acids present in each peptide and adjacent peptides in the data set. Using these vectors, the method then generates an algorithm from the plurality of vectors and the calculated probabilities that specific peptides in the data set were detected in the repeated analysis. The algorithm is thus capable of calculating the probability that a hypothetical peptide represented as a vector will be detected by a mass spectrometry based proteomic platform, given that the peptide is present in a sample introduced into a mass spectrometer.

摘要翻译： 通过用质谱仪分析来检测存在于生物样品中的肽的方法。 该方法使用至少一种质谱仪对含有已知氨基酸的蛋白质的含有肽的样品进行重复分析。 然后，该方法通过重复分析产生被鉴定为包含在样品内的肽的数据集。 然后，该方法计算在重复分析中检测到数据集中的特定肽的概率。 该方法然后创建多个向量，其中每个载体具有多个维度，并且每个维度表示存在于每个肽中的一个或多个氨基酸和数据集中的相邻肽的性质。 使用这些向量，该方法然后从多个向量生成算法，并且在重复分析中检测出数据集中的特定肽的计算概率。 因此，鉴于该肽存在于引入质谱仪的样品中，该算法因此能够计算出通过基于质谱的蛋白质组学平台检测表示为载体的假定肽的概率。

公开(公告)号：US20070228349A1

公开(公告)日：2007-10-04

申请号：US11393972

申请日：2006-03-30

申请人： Richard Smith

发明人： Richard Smith

IPC分类号： E01F7/02

CPC分类号： E01F13/028 ,  E04H12/2215

摘要： An assembly for creating a portable enclosure includes a plurality of individual and elongated ground engaging units, each having an elongated body and an end extending ground engaging portion. A magazine fixedly secures in vertically extending fashion along each of the units, a screen adapted to being withdrawn from the magazine and including hooks defined along a forward withdrawable edge. A plurality of rings extend along a further vertically extending edge associated with each of the units, and which is adapted to receive the hooks associated with a screen withdrawn from a succeeding located unit, in order to construct a barrier between the units.

摘要翻译： 用于创建便携式外壳的组件包括多个单独和细长的地面接合单元，每个具有细长主体和延伸地面接合部分的端部。 盒子沿着每个单元以垂直延伸的方式固定地固定，一个适于从盒中取出并包括沿着可向前抽出的边缘限定的钩子的屏幕。 多个环沿着与每个单元相关联的另一个垂直延伸的边缘延伸，并且其适于接收与从后续位置单元退出的屏幕相关联的钩，以便在单元之间构造屏障。

公开(公告)号：US20070194224A1

公开(公告)日：2007-08-23

申请号：US11346799

申请日：2006-02-02

申请人： Keqi Tang ,  Jason Page ,  Quanzhou Luo ,  Richard Smith

发明人： Keqi Tang ,  Jason Page ,  Quanzhou Luo ,  Richard Smith

IPC分类号： H01J49/10

CPC分类号： H01J49/167 ,  G01N30/7266

摘要： Electrospray ionization (ESI) apparatuses and methods of making the same are disclosed. In one embodiment, an ESI emitter comprises a capillary tube filled with a porous monolithic material, wherein the end of the emitter is tapered and the tip of the tapered end comprises a protrusion of the porous monolithic material. One embodiment of the method for making ESI emitters comprises filling a capillary tube with a porous monolithic material and tapering the end of the capillary tube, thereby exposing a portion of the porous material. The exposed portion of the porous material at the tapered end, rather than the capillary tube itself, forms the tip of the ESI emitter.

摘要翻译： 公开了电喷雾离子化（ESI）装置及其制备方法。 在一个实施例中，ESI发射器包括填充有多孔整体材料的毛细管，其中发射器的端部是锥形的，锥形末端包括多孔整体材料的突起。 用于制备ESI发射器的方法的一个实施例包括用多孔整体材料填充毛细管并使毛细管的端部逐渐变细，由此暴露多孔材料的一部分。 锥形端部的多孔材料的暴露部分而不是毛细管本身形成ESI发射体的尖端。

公开(公告)号：US20070191411A1

公开(公告)日：2007-08-16

申请号：US11246883

申请日：2005-10-07

申请人： Richard Smith

发明人： Richard Smith

IPC分类号： A61K31/485 ,  A61K31/4745

CPC分类号： A61K31/485 ,  A61K31/4709 ,  A61K31/4745 ,  A61K45/06 ,  A61K47/22 ,  A61K2300/00

摘要： During clinical trials on patients suffering from neurological disorders, it has been observed that some patients obtain dramatic improvements in motor control and/or higher mental functioning, when they receive a combination of dextromethorphan and quinidine, at suitable dosages. Improved motor control has been exemplified to date by improved ability to swallow and/or speak, among victims of stroke, head injury, or ALS. Improved higher mental functioning has been exemplified better job performance, increased ability to analyze and solve problems, and increased ability to have successful and satisfying interactions with other people. These types of effects can be seen in a relatively brief time period, such as within several days to a week.

摘要翻译： 在对患有神经障碍的患者的临床试验期间，已经观察到，当以合适的剂量接受右美沙芬和奎尼丁的组合时，一些患者在运动控制和/或较高的精神功能方面获得显着改善。 在中风，头部受伤或ALS的受害者中，通过改善吞咽和/或说话的能力，已经改进了运动控制。 改善了更高的心理功能已被列为更好的工作表现，增加分析和解决问题的能力，以及增加与其他人取得成功和令人满意的互动的能力。 这些类型的效果可以在相对短的时间内看到，例如在几天到一周之内。

公开(公告)号：US20070135679A1

公开(公告)日：2007-06-14

申请号：US11301912

申请日：2005-12-13

申请人： John Hunt ,  Michael Cropper ,  Richard Smith ,  Richard Schwemberger ,  John Measamer

发明人： John Hunt ,  Michael Cropper ,  Richard Smith ,  Richard Schwemberger ,  John Measamer

IPC分类号： A61B1/00

CPC分类号： A61B1/31 ,  A61B1/00154 ,  A61B17/3421 ,  A61B17/3462 ,  A61B2017/3452 ,  A61B2017/347 ,  A61B2017/3492

摘要： A colonoscopic device stabilizer for stabilizing a colonoscopic device when inserted in an anus of a patient. The stabilizer includes a body adapted for receipt within the anus of a patient. The body has an opening sized and shaped for receiving the colonoscopic device when the device is inserted in the anus of the patient. The stabilizer also includes a clamp attached to the body selectively moveable between a locked position in which the clamp resists movement of the colonoscopic device relative to the body and an unlocked position in which the clamp permits movement of the colonoscopic device relative to the body.

摘要翻译： 一种用于在插入患者肛门时稳定结肠镜装置的结肠镜装置稳定器。 稳定器包括适于在患者的肛门内接收的主体。 身体具有开口尺寸和形状，用于当将装置插入患者的肛门时接收结肠镜装置。 稳定器还包括附接到身体的夹具，其选择性地可在其中夹具抵抗结肠镜检查装置相对于身体的移动的锁定位置和夹具允许结肠镜装置相对于身体移动的解锁位置之间移动。