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    Renal Nerve Ablation Using Mild Freezing and Vibration
    101.
    发明申请
    Renal Nerve Ablation Using Mild Freezing and Vibration 审中-公开
    使用轻度冷冻和振动的肾神经消融

    公开(公告)号：US20120123261A1

    公开(公告)日：2012-05-17

    申请号：US13243114

    申请日：2011-09-23

    Applicant: Mark L. Jenson ,  Scott Smith

    Inventor： Mark L. Jenson ,  Scott Smith

    IPC: A61N7/00 ,  A61B8/12 ,  A61H1/00

    CPC classification number: A61B8/0841 ,  A61B8/12 ,  A61B8/4488 ,  A61B17/22004 ,  A61B17/2202 ,  A61B18/02 ,  A61B18/0206 ,  A61B2017/22008 ,  A61B2017/22024 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61N7/022

    Abstract: A catheter includes a thermal unit provided at its distal end and configured to receive a thermal transfer fluid. The thermal unit is configured to cause formation of ice particles in perivascular renal nerve tissue adjacent the thermal unit and warm tissue of the renal artery adjacent the thermal unit to a temperature above freezing while ice particles remain formed in the perivascular renal nerve tissue. A vibration source is configured to generate vibration of the ice particles sufficient to disrupt perivascular renal nerve tissue and terminate sympathetic renal nerve activity with no or negligible damage to thawed renal artery tissue. The vibration source may be configured to generate vibration sufficient to nucleate ice formation within at least the perivascular renal nerve tissue so that ice particles form throughout the perivascular renal nerve tissue adjacent the thermal unit.

    Abstract translation: 导管包括设置在其远端处并构造成接收热传递流体的热单元。 热单元被配置成在邻近热单元的热单元和肾动脉附近的血管周围肾神经组织中形成冰颗粒至高于冰点的温度，同时在血管周围肾神经组织中保持形成冰颗粒。 振动源被配置为产生足以破坏血管周围肾神经组织的冰粒的振动，并终止对解冻的肾动脉组织没有或可忽略的损伤的交感神经肾神经活动。 振动源可以被配置为产生足以使至少血管周围肾神经组织内的冰形成成核的振动，使得冰颗粒在与热单元相邻的血管周围肾神经组织中形成。

    Renal Nerve Ablation Using Conductive Fluid Jet and RF Energy
    102.
    发明申请
    Renal Nerve Ablation Using Conductive Fluid Jet and RF Energy 有权
    使用导电流体射流和射频能量进行肾神经消融

    公开(公告)号：US20120101490A1

    公开(公告)日：2012-04-26

    申请号：US13280784

    申请日：2011-10-25

    Applicant: Scott Smith

    Inventor： Scott Smith

    IPC: A61B18/18

    CPC classification number: A61B17/3203 ,  A61B17/3478 ,  A61B18/1492 ,  A61B2017/00247 ,  A61B2018/00029 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2218/002

    Abstract: An ablation catheter is dimensioned for advancement through a vessel of the body. The catheter includes a lumen configured to receive a pressurized electrically conductive fluid. A nozzle is fluidly coupled to the distal end of the pressurizable lumen and configured to direct a jet of the pressurized conductive fluid at a wall of a target vessel, such as a renal artery, to create or expand a hole through the target vessel and to fill the hole and at least some of the space adjacent to the hole with the conductive fluid. An electrical conductor extends at least partially along the catheter and terminates proximate or at the distal end of the pressurizable lumen. The electrical conductor is configured to conduct radiofrequency energy to the conductive fluid sufficient to ablate target tissue, such as perivascular renal nerve tissue, proximate the hole.

    Abstract translation: 消融导管的尺寸用于通过身体的血管前进。 导管包括构造成接收加压导电流体的内腔。 喷嘴流体地联接到可加压内腔的远端并且构造成将目标血管（例如肾动脉）的壁处的加压导电流体的射流引导以产生或扩大穿过靶容器的孔，并且 用导电流体填充孔和邻近孔的至少一些空间。 电导体至少部分地沿着导管延伸并且终止于可加压腔的近端或远端。 电导体被配置为将射频能量传导到导电流体，该导电流体足以消融靠近孔的靶组织，例如血管周围肾神经组织。

    Cooled Conductive Balloon RF Catheter for Renal Nerve Ablation
    103.
    发明申请
    Cooled Conductive Balloon RF Catheter for Renal Nerve Ablation 有权
    冷气导气球射频导管用于肾神经消融

    公开(公告)号：US20120029511A1

    公开(公告)日：2012-02-02

    申请号：US13188677

    申请日：2011-07-22

    Applicant: Scott Smith ,  Joe Koblish ,  Mark L. Jenson ,  Roger Hastings

    Inventor： Scott Smith ,  Joe Koblish ,  Mark L. Jenson ,  Roger Hastings

    IPC: A61B18/14

    CPC classification number: A61B18/1492 ,  A61B2018/00029 ,  A61B2018/00035 ,  A61B2018/00065 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00238 ,  A61B2018/00285 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00821 ,  A61B2018/1472

    Abstract: A catheter includes a flexible shaft having a lumen arrangement and a length sufficient to access a target vessel of a patient. A balloon at the distal end of the shaft is fluidly coupled to the lumen arrangement. The balloon body comprises a first material and a second material different from the first material. The second material comprises a hydrophilic polymer that becomes electrically conductive in response to absorption of the conductive fluid. The fluid conductive regions facilitate perfusion of the conductive fluid through the balloon body to an inner wall of the target vessel during ablation of perivascular tissues. A cooling arrangement is configured for one of receiving a thermal transfer fluid from the lumen arrangement or facilitating perfusion of blood passing through the target vessel to cool the balloon body during ablation of the perivascular tissues.

    Abstract translation: 导管包括柔性轴，其具有管腔布置和足以进入患者的目标血管的长度。 在轴的远端处的气囊流体地联接到管腔装置。 球囊体包括第一材料和与第一材料不同的第二材料。 第二种材料包括响应于导电流体的吸收变得导电的亲水性聚合物。 流体导电区域便于在血管周围组织消融期间将导电流体通过球囊体灌注到目标血管的内壁。 冷却装置构造成用于接收来自管腔装置的热转移流体，或者促进血液通过靶血管的灌注，以在血管周围组织消融期间冷却球囊体。

    Methods, circuits, and systems to select memory regions
    106.
    发明授权
    Methods, circuits, and systems to select memory regions 有权
    方法，电路和系统来选择内存区域

    公开(公告)号：US07961542B2

    公开(公告)日：2011-06-14

    申请号：US12581747

    申请日：2009-10-19

    Applicant: Scott Smith

    Inventor： Scott Smith

    IPC: G11C7/00

    CPC classification number: G11C11/4082 ,  G06F12/02 ,  G06F2212/1028 ,  G11C8/12 ,  G11C11/406 ,  G11C11/40615 ,  G11C11/40622 ,  G11C11/4087 ,  Y02D10/13

    Abstract: Embodiments for selecting regions of memory are described. For example, in one embodiment a memory device having an array of memory cells includes an array selection block. The array selection block receives an input signal indicative of a region in the array of memory cells. The array selection block generates a selection signal to map the region to at least one physical location in the array of memory cells, based on the detection of the number of defects in that location.

    Abstract translation: 描述用于选择存储器区域的实施例。 例如，在一个实施例中，具有存储器单元阵列的存储器件包括阵列选择块。 阵列选择块接收指示存储器单元阵列中的区域的输入信号。 基于检测到该位置中的缺陷数目，阵列选择块产生选择信号以将该区域映射到存储器单元阵列中的至少一个物理位置。

    IMAGE SENSORS AND IMAGE RECONSTRUCTION METHODS FOR CAPTURING HIGH DYNAMIC RANGE IMAGES
    108.
    发明申请
    IMAGE SENSORS AND IMAGE RECONSTRUCTION METHODS FOR CAPTURING HIGH DYNAMIC RANGE IMAGES 有权
    用于捕获高动态范围图像的图像传感器和图像重建方法

    公开(公告)号：US20100309333A1

    公开(公告)日：2010-12-09

    申请号：US12480651

    申请日：2009-06-08

    Applicant: Scott Smith ,  Peng Lin ,  Christopher Zeleznik ,  Laura Savidge

    Inventor： Scott Smith ,  Peng Lin ,  Christopher Zeleznik ,  Laura Savidge

    IPC: H04N5/235

    CPC classification number: H04N9/045 ,  H04N5/235 ,  H04N5/2355 ,  H04N2209/046

    Abstract: High dynamic range image sensors and image reconstruction methods for capturing high dynamic range images. An image sensor that captures high dynamic range images may include an array of pixels having two sets of pixels, each of which is used to capture an image of a scene. The two sets of pixels may be interleaved together. As an example, the first and second sets of pixels may be formed in odd-row pairs and even-row pairs of the array, respectively. The first set of pixels may use a longer exposure time than the second set of pixels. The exposures of the two sets of pixels may at least partially overlap in time. Image processing circuitry in the image sensors or an associated electronic device may de-interlace the two images and may combine the de-interlaced images to form a high dynamic range image.

    Abstract translation: 高动态范围图像传感器和用于捕获高动态范围图像的图像重建方法。 捕获高动态范围图像的图像传感器可以包括具有两组像素的像素阵列，每组像素用于捕获场景的图像。 两组像素可以交错在一起。 作为示例，第一和第二组像素可以分别形成为阵列的奇数行和偶数行。 第一组像素可以使用比第二组像素更长的曝光时间。 两组像素的曝光可能在时间上至少部分重叠。 图像传感器或相关联的电子设备中的图像处理电路可以对两个图像进行去隔行扫描，并且可以组合去隔行图像以形成高动态范围图像。

    METHODS, CIRCUITS, AND SYSTEMS TO SELECT MEMORY REGIONS
    109.
    发明申请
    METHODS, CIRCUITS, AND SYSTEMS TO SELECT MEMORY REGIONS 有权
    选择存储区域的方法，电路和系统

    公开(公告)号：US20100034034A1

    公开(公告)日：2010-02-11

    申请号：US12581747

    申请日：2009-10-19

    Applicant: Scott Smith

    Inventor： Scott Smith

    IPC: G11C7/00 ,  G11C29/00

    CPC classification number: G11C11/4082 ,  G06F12/02 ,  G06F2212/1028 ,  G11C8/12 ,  G11C11/406 ,  G11C11/40615 ,  G11C11/40622 ,  G11C11/4087 ,  Y02D10/13

    Abstract: Embodiments for selecting regions of memory are described. For example, in one embodiment a memory device having an array of memory cells includes an array selection block. The array selection block receives an input signal indicative of a region in the array of memory cells. The array selection block generates a selection signal to map the region to at least one physical location in the array of memory cells, based on the detection of the number of defects in that location.

    Abstract translation: 描述用于选择存储器区域的实施例。 例如，在一个实施例中，具有存储器单元阵列的存储器件包括阵列选择块。 阵列选择块接收指示存储器单元阵列中的区域的输入信号。 基于检测到该位置中的缺陷数目，阵列选择块产生选择信号以将该区域映射到存储器单元阵列中的至少一个物理位置。

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