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101.发明申请公开(公告)号：US20170357768A1
公开(公告)日：2017-12-14
申请号：US15668956
申请日：2017-08-04
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
Abstract: A method for at least one of characterizing, diagnosing, and treating a locomotor system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the locomotor system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the locomotor system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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102.发明申请公开(公告)号：US20170344719A1
公开(公告)日：2017-11-30
申请号：US15679633
申请日：2017-08-17
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
Abstract: A method for at least one of characterizing, diagnosing, and treating a locomotor system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the locomotor system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the locomotor system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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103.发明申请公开(公告)号：US20170329897A1
公开(公告)日：2017-11-16
申请号：US15655587
申请日：2017-07-20
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G16B30/00 , C12Q1/689 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , G06F19/3418 , G06F19/3456 , G16B5/00 , G16B40/00 , G16B50/00 , G16H20/10 , G16H40/67 , G16H50/20 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating an endocrine system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the endocrine system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the endocrine system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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104.发明申请公开(公告)号：US20170316152A1
公开(公告)日：2017-11-02
申请号：US15655640
申请日：2017-07-20
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G16B30/00 , C12Q1/689 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , G06F19/3418 , G06F19/3456 , G16B5/00 , G16B40/00 , G16B50/00 , G16H50/20 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating an endocrine system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the endocrine system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the endocrine system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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105.发明申请公开(公告)号：US20170308660A1
公开(公告)日：2017-10-26
申请号：US15645102
申请日：2017-07-10
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: G16H50/20 , C40B30/02 , G06F19/00 , G06F19/24 , G06F19/28 , G06F19/3418 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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Patent Agency Ranking
106.发明申请公开(公告)号：US20170308658A1
公开(公告)日：2017-10-26
申请号：US15645008
申请日：2017-07-10
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: G16H50/20 , C40B30/02 , G06F19/00 , G06F19/24 , G06F19/28 , G06F19/3418 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing, and treating an autoimmune disorder in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the autoimmune condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the autoimmune condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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107.发明申请公开(公告)号：US20170286612A1
公开(公告)日：2017-10-05
申请号：US15621420
申请日：2017-06-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G16H40/67 , G06F19/3418 , G16B35/00 , G16B40/00 , G16B50/00 , G16B50/50 , G16C20/60 , G16H20/00 , G16H50/20 , G16H50/50 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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108.发明申请公开(公告)号：US20170277848A1
公开(公告)日：2017-09-28
申请号：US15621445
申请日：2017-06-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
CPC classification number: G16H40/67 , G06F19/3418 , G16B35/00 , G16B40/00 , G16B50/00 , G16B50/50 , G16C20/60 , G16H20/00 , G16H50/20 , G16H50/50 , Y02A90/26
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US20170270272A1
公开(公告)日：2017-09-21
申请号：US15606975
申请日：2017-05-26
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
CPC classification number: G16H40/67 , C12Q1/68 , C12Q1/6883 , C12Q1/689 , C12Q2600/118 , G06F19/30 , G06F19/3418 , G16B5/00 , G16B50/00 , G16B99/00 , G16H20/10 , G16H50/20 , G16H50/50 , Y02A90/26
Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US20170053061A1
公开(公告)日：2017-02-23
申请号：US15240919
申请日：2016-08-18
Applicant: uBiome, Inc.
Inventor： Daniel Almonacid , Zachary Apte , Jessica Richman
CPC classification number: G16B25/00 , C12Q1/6806 , C12Q1/6844 , G01N35/0099 , G01N2035/00881 , G16B30/00 , G16B35/00 , G16C20/60 , G16C99/00 , C12Q2537/143 , C12Q2537/165
Abstract: A method and system for selection of a primer set for a set of target sequences includes: identifying candidate fragments upon performance of a comparison operation with the set of target sequences; identifying a forward subset of unique forward candidates and a reverse subset of unique reverse candidates; reducing the forward subset and the reverse subset based on a filtering operation; performing an in silico search operation with the reduced forward subset and the reduced reverse subset; generating a set of candidate degenerate primers based on the in silico search operation and a base mismatch criterion; generating a reduced set of candidate degenerate primers upon filtering the set of candidate degenerate primers according to the set of primer criteria; and selecting forward primer subsets that amplify the set of target sequences and identifying a reverse primer subset for each of the forward primer subsets with an in silico PCR operation.
Abstract translation: 用于选择一组目标序列的引物组的方法和系统包括：在与所述靶序列集合执行比较操作时识别候选片段; 识别唯一前向候选的前向子集和唯一逆向候选的反向子集; 基于过滤操作减少前向子集和反向子集; 用减少的前向子集和减少的反向子集执行计算机搜索操作; 基于计算机搜索操作和基本不匹配标准生成一组候选简并引物; 在根据引物标准集过滤所述候选简并引物组后，产生一组降低的候选简并引物; 以及选择扩增靶序列集合的正向引物亚类，并使用计算机内PCR操作来识别每个正向引物子集的反向引物子集。
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