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    System and Method for Building and Manipulating a Centralized Measurement Value Database
    111.
    发明申请
    System and Method for Building and Manipulating a Centralized Measurement Value Database 审中-公开
    建立和操纵集中测量值数据库的系统和方法

    公开(公告)号：US20080097794A1

    公开(公告)日：2008-04-24

    申请号：US11953455

    申请日：2007-12-10

    Applicant: Claude Arnaud ,  Barry Linder ,  Daniel Steines ,  Philipp Lang

    Inventor： Claude Arnaud ,  Barry Linder ,  Daniel Steines ,  Philipp Lang

    IPC: G06Q50/00

    CPC classification number: G06Q50/24 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/7264 ,  A61B6/4423 ,  A61B6/505 ,  A61B6/508 ,  A61B6/563 ,  A61B6/583 ,  G06F19/321 ,  G06K2009/00946 ,  G06Q30/02 ,  G06Q50/22 ,  G06T7/80 ,  G06T2207/10116 ,  G06T2207/30036 ,  G16H10/60 ,  G16H50/30 ,  G16H50/80

    Abstract: A system and method for building and/or manipulating a centralized medical image quantitative information database aid in diagnosing diseases, identifying prevalence of diseases, and analyzing market penetration data and efficacy of different drugs. In one embodiment, the diseases are bone-related, such as osteoporosis and osteoarthritis. Subjects' medical images, personal and treatment information are obtained at information collection terminals, for example, at medical and/or dental facilities, and are transferred to a central database, either directly or through a system server. Quantitative information is derived from the medical images, and stored in a central database, associated with subjects' personal and treatment information. Authorized users, such as medical officials and/or pharmaceutical companies, can access the database, either directly or through the central server, to diagnose diseases and perform statistical analysis on the stored data. Decisions can be made regarding marketing of drugs for treating the diseases in question, based on analysis of efficacy, market penetration, and performance of competitive drugs.

    Abstract translation: 一种用于建立和/或操纵集中式医学图像定量信息数据库的系统和方法，用于诊断疾病，确定疾病流行率，分析不同药物的市场渗透数据和功效。 在一个实施方案中，疾病是骨相关的，例如骨质疏松症和骨关节炎。 在信息收集终端（例如医疗和/或牙科设施）处获得受试者的医学图像，个人和治疗信息，并且直接或通过系统服务器传送到中央数据库。 定量信息来自医学图像，并存储在与受试者的个人和治疗信息相关联的中央数据库中。 授权用户（如医务人员和/或制药公司）可以直接或通过中央服务器访问数据库，以诊断疾病并对存储的数据执行统计分析。 根据有效性，市场渗透性和竞争性药物的表现分析，可以作出有关药物治疗有关疾病的销售决定。

    Implant Grasper
    114.
    发明申请
    Implant Grasper 审中-公开
    植入者抓住

    公开(公告)号：US20070156171A1

    公开(公告)日：2007-07-05

    申请号：US11562724

    申请日：2006-11-22

    Applicant: Philipp Lang ,  Albert Burdulis ,  Wolfgang Fitz

    Inventor： Philipp Lang ,  Albert Burdulis ,  Wolfgang Fitz

    IPC: A61B17/00

    CPC classification number: A61F2/461 ,  A61B2017/2808 ,  A61F2/3872 ,  A61F2002/4622

    Abstract: A device for grasping an implant is provided. The implant has a first and second surface, with at least one of the first and seconds surfaces being non-planar. The device includes a first grasping element having a first grasping surface that conforms to the first surface of the implant, and a second grasping element having a second grasping surface conforming to the second surface of the implant. At least one of the first grasping element and the second grasping element can be moved to grasp the implant, such that the first grasping surface contacts the first surface of the implant and the second grasping surface contacts the second surface of the implant.

    Abstract translation: 提供了一种用于抓握植入物的装置。 植入物具有第一和第二表面，第一和第二表面中的至少一个是非平面的。 该装置包括具有与植入物的第一表面一致的第一抓握表面的第一抓握元件和具有与植入物的第二表面相符的第二抓握表面的第二抓握元件。 第一抓握元件和第二抓握元件中的至少一个可以移动以抓住植入物，使得第一抓握表面接触植入物的第一表面，并且第二抓握表面接触植入物的第二表面。

    Assessing the condition of a joint and devising treatment
    115.
    发明授权
    Assessing the condition of a joint and devising treatment 有权
    评估联合和设计治疗的状况

    公开(公告)号：US07239908B1

    公开(公告)日：2007-07-03

    申请号：US09662224

    申请日：2000-09-14

    Applicant: Eugene J. Alexander ,  Thomas P. Andriacchi ,  Philipp Lang ,  Daniel Steines

    Inventor： Eugene J. Alexander ,  Thomas P. Andriacchi ,  Philipp Lang ,  Daniel Steines

    IPC: A61B5/05

    CPC classification number: G09B23/30 ,  A61B5/055 ,  A61B5/103 ,  A61B5/1038 ,  A61B5/112 ,  A61B5/1121 ,  A61B5/1122 ,  A61B5/1127 ,  A61B5/4514 ,  A61B5/4528 ,  A61B5/7257

    Abstract: Methods are disclosed for assessing the condition of a cartilage in a joint, particularly a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. Information on thickness of cartilage and curvature of cartilage or subchondral bone can be used to plan therapy. Information on movement pattern can be used to plan therapy.

    Abstract translation: 公开了评估关节，特别是人膝关节软骨状况的方法。 所述方法包括将诸如MRI的图像转换为软骨的三维图。 软骨图可以与关节的运动模式相关联，以评估运动对软骨磨损的影响。 随着时间的推移，可以确定软骨厚度的变化，从而可以提供治疗。 关于软骨厚度和软骨或软骨下骨曲率的信息可用于计划治疗。 运动模式信息可用于计划治疗。

    Methods and devices for analysis of x-ray images
    117.
    发明申请
    Methods and devices for analysis of x-ray images 审中-公开
    用于分析x射线图像的方法和装置

    公开(公告)号：US20070047794A1

    公开(公告)日：2007-03-01

    申请号：US11514278

    申请日：2006-08-31

    Applicant: Philipp Lang ,  Daniel Steines

    Inventor： Philipp Lang ,  Daniel Steines

    IPC: G06K9/00

    CPC classification number: G06T7/0012 ,  A61B6/4423 ,  A61B6/482 ,  A61B6/505 ,  A61B6/583

    Abstract: The present invention relates to methods and devices for analyzing x-ray images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure from x-ray images.

    Abstract translation: 本发明涉及用于分析X射线图像的方法和装置。 特别地，提供了允许从x射线图像准确可靠地评估骨骼结构的装置，方法和算法。

    Clckb mutation as a diagnostic and therapeutical target
    120.
    发明申请
    Clckb mutation as a diagnostic and therapeutical target 失效
    Clckb突变作为诊断和治疗靶点

    公开(公告)号：US20050084485A1

    公开(公告)日：2005-04-21

    申请号：US10687523

    申请日：2003-10-15

    Applicant: Florian Lang ,  Siegfried Waldegger ,  Philipp Lang ,  Angelika Lampert ,  Hannsjoerg Seybert ,  Nikola Jeck

    Inventor： Florian Lang ,  Siegfried Waldegger ,  Philipp Lang ,  Angelika Lampert ,  Hannsjoerg Seybert ,  Nikola Jeck

    IPC: C12Q1/68 ,  A61K38/48 ,  C07H21/04 ,  C12N9/12

    CPC classification number: C12Q1/6883 ,  C12Q2600/156

    Abstract: The present invention relates to a method for diagnosing hypertension, and/or allergy, and/or hair loss, and/or liabilty for infection, of a human being, or a predisposition therefor; to a nucleic acid molecule coding for a human ClCKb protein comprising a genetic alteration at amino acid position 481 compared to the wild type, as well as for corresponding segments thereof; to a nucleic acid molecule which binds to the before-mentioned nucleic acid molecule under stringent conditions, as well as to a nucleic acid molecule which binds to that nucleic acid molecule; to a (poly)peptide encoded by the afore-mentioned nucleic acid molecules; to a method for identifying substances modulating activity of a peptide derived from ClCKb protein that is genetically altered at amino acid position 481 compared to the wild type; to a substance for modulating activity of a peptide derived from ClCKb protein that is genetically altered at amino acid position 481 compared to the wild type; to methods for preparing a pharmaceutical composition for treatment of hypertension, and/or allergy, and/or hair loss, and/or liability for infection; to pharmaceutical compositions; and to a method for treating a human being affected by hypertension, and/or allergy and/or hair loss, and/or liability for infection.

    Abstract translation: 本发明涉及一种用于诊断人类或其易感性的高血压，/或过敏和/或脱发，和/或感染的可能性的方法; 涉及编码人类ClCKb蛋白质的核酸分子，其包含与野生型相比在氨基酸位置481处的遗传改变，以及其对应的片段; 涉及在严格条件下与前述核酸分子结合的核酸分子，以及与该核酸分子结合的核酸分子; 涉及由上述核酸分子编码的（多）肽; 涉及一种用于鉴定与野生型相比在氨基酸位置481遗传改变的来自ClCKb蛋白的肽调节活性的物质的方法; 涉及调节与野生型相比在氨基酸位置481遗传改变的来自ClCKb蛋白的肽的活性的物质; 制备用于治疗高血压和/或过敏和/或脱发的药物组合物和/或感染责任的方法; 至药物组合物; 以及治疗受高血压，/或过敏和/或脱发影响的人的方法和/或感染责任。

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