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公开(公告)号：US20020193300A1
公开(公告)日：2002-12-19
申请号：US09990444
申请日：2001-11-14
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
IPC: A61K038/17 , C12P021/02 , C07K014/435 , C12N005/06 , C12Q001/68 , C07H021/04 , C12N009/00
CPC classification number: C07K14/47 , A61K38/00 , A61K39/00 , C07K14/52 , C07K14/705 , C07K16/18 , C07K2319/00 , C12N9/00 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/57484 , G01N33/68 , G01N33/6842 , Y10S530/866
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20020177188A1
公开(公告)日：2002-11-28
申请号：US09874503
申请日：2001-06-05
Applicant: GENENTECH, INC.
Inventor： Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Sarah G. Hymowitz , Daniel Tumas , Melissa A. Starvovasnik , Menno Van Lookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel G. Yansura
IPC: C07K014/715 , C07H021/04 , C12P021/02 , C12N005/06
CPC classification number: C07H21/04 , C07K14/715 , C12N5/06 , C12P21/02
Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
Abstract translation: 本发明涉及与IL-17，IL-17受体和编码那些多肽的核酸分子具有序列同一性的新型多肽。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本文还提供了治疗退行性软骨疾病和其它炎性疾病的方法。
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公开(公告)号：US20020156006A1
公开(公告)日：2002-10-24
申请号：US09978295
申请日：2001-10-15
Applicant: Genentech, Inc.
Inventor： Avi Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: A61K038/17 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435 , C07K016/40
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4702 , C07K14/4703 , C07K14/475 , C07K14/52 , C07K14/521 , C07K14/54 , C07K14/705 , C07K14/70503 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N9/00 , C12N2799/026 , C12N2799/027 , G01N33/573 , G01N33/57484 , G01N33/68 , G01N2333/99 , G01N2800/042
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20020132253A1
公开(公告)日：2002-09-19
申请号：US09991163
申请日：2001-11-14
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
IPC: C12Q001/68 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , A61K38/00 , A61K39/00 , C07K14/52 , C07K14/705 , C07K16/18 , C07K2319/00 , C12N9/00 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/57484 , G01N33/68 , G01N33/6842 , Y10S530/866
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20020132252A1
公开(公告)日：2002-09-19
申请号：US09990442
申请日：2001-11-14
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
IPC: C12Q001/68 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , A61K38/00 , A61K39/00 , C07K14/52 , C07K14/705 , C07K16/18 , C07K2319/00 , C12N9/00 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/57484 , G01N33/68 , G01N33/6842 , Y10S530/866
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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Patent Agency Ranking
公开(公告)号：US20020132240A1
公开(公告)日：2002-09-19
申请号：US09909320
申请日：2001-07-18
Applicant: Genentech, Inc.
Inventor： Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20040258678A1
公开(公告)日：2004-12-23
申请号：US10370715
申请日：2003-02-21
Applicant: Genentech, Inc.
Inventor： Sarah C. Bodary , Hilary Clark , Brisdell Hunte , Janet K. Jackman , Jill R. Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
IPC: A61K039/395 , C07H021/04 , C12N009/00
CPC classification number: G01N33/564 , A61K38/00 , C07K14/47
Abstract: The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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公开(公告)号：US20040048332A1
公开(公告)日：2004-03-11
申请号：US09999831
申请日：2001-10-24
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: C12P021/02 , C12N005/06 , C07K014/47 , C07H021/04 , C12N009/00
CPC classification number: C07K16/18 , C07K14/47 , C07K14/4703 , C07K14/705 , C07K2319/00 , C07K2319/30 , C12N2799/026
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20040005626A1
公开(公告)日：2004-01-08
申请号：US10011795
申请日：2001-12-07
Applicant: Genentech, Inc.
Inventor： Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12N005/06 , C12P021/02 , C07K014/435 , C07K016/40
CPC classification number: C07K14/47 , C07K14/705
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20040005312A1
公开(公告)日：2004-01-08
申请号：US10145093
申请日：2001-10-18
Applicant: Genentech, Inc.
Inventor： Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: A61K039/395 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/47
CPC classification number: C07K14/47 , C07K14/705
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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