摘要:
Disclosed are methods and compositions for modulating the function of transcription factors, especially transcription factors that recruit epigenetic regulators (histone modifying enzymes) to specific DNA promoters. The targeted transcription factors include but are not limited to the myocyte enhancing factor (MEF2), the forkhead/winged helix transcription factor FOXP3 and the transcription factor GATA3. Also disclosed are small molecule modulators of MEF2 and its associated factors that include but not limited to histone deacetylases (HDACs), p300/CBP and Cabin1 and the therapeutic applications thereof.
摘要:
This disclosure describes techniques for selectively activating a resume check operation in a single instruction, multiple data (SIMD) processing system. A processor is described that is configured to selectively enable or disable a resume check operation for a particular instruction based on information included in the instruction that indicates whether a resume check operation is to be performed for the instruction. A compiler is also described that is configured to generate compiled code which, when executed, causes a resume check operation to be selectively enabled or disabled for particular instructions. The compiled code may include one or more instructions that each specify whether a resume check operation is to be performed for the respective instruction. The techniques of this disclosure may be used to reduce the power consumption of and/or improve the performance of a SIMD system that utilizes a resume check operation to manage the reactivation of deactivated threads.
摘要:
The present invention relates to polypeptides from Plasmodium and polynucleotides encoding the polypeptides. The invention further relates to compositions comprising the polypeptides and their use in the treatment and prevention of malaria.
摘要:
A method for selecting a channel for an access point (AP) in a Wireless Local Area Network (WLAN). The method includes the AP receiving network conditions of APs within the sensing range of a terminal sent by the terminal, and the AP selecting a channel based on the received network conditions. By forwarding the network conditions of other APs which can be detected by the terminal, the method of the present invention enables an AP to select a channel from the view of a terminal to avoid conflicts at the terminal, thereby improving the available bandwidth of the terminal, and giving a better experience to users.
摘要:
A system and a method for replicating data among heterogeneous databases are described. The system includes an initialization module for creating and initializing shared memory, a message queue and a semaphore; a processing module including a data reader, a data adapter and a data loader; a replication module for replicating the data in the shared memory to a target database according to the messages in the message queue; and a cleaning module for releasing the shared memory after the replication. The method includes creating and initializing the shared memory, the message queue and the semaphore; reading data from the source database, then converting the data into target data for a target database, and loading the target data in the shared memory; replicating the target data in the shared memory to the target database according to the messages in the message queue; and releasing the shared memory after the replication.
摘要:
A method and system for performing byte-writes are described, where byte-writes involve writing only particular bytes of a multiple byte write operation. Embodiments include mask data that indicates which bytes are to be written in a byte-write operation. No dedicated mask pin(s) or dedicated mask line(s) are used. In one embodiment, the mask data is transmitted on data lines and store in response to a write_mask command. In one embodiment, the mask data is transmitted as part of the write command.
摘要:
This disclosure describes techniques for handling divergent thread conditions in a multi-threaded processing system. In some examples, a control flow unit may obtain a control flow instruction identified by a program counter value stored in a program counter register. The control flow instruction may include a target value indicative of a target program counter value for the control flow instruction. The control flow unit may select one of the target program counter value and a minimum resume counter value as a value to load into the program counter register. The minimum resume counter value may be indicative of a smallest resume counter value from a set of one or more resume counter values associated with one or more inactive threads. Each of the one or more resume counter values may be indicative of a program counter value at which a respective inactive thread should be activated.
摘要:
The present disclosure includes system and method of mapping shader variables into physical registers. In an embodiment, a graphics processing unit (GPU) and a memory coupled to the GPU are disclosed. The memory includes a processor readable data file that has a register file portion. The register file portion has a rectangular structure including a plurality of data items. At least two of the plurality of data items corresponding to data elements of a shader program. The data elements have different data storage types.
摘要:
Techniques are described for managing failover in redundant network devices. In particular, each device in a set of redundant network devices includes redundant processing modules. Each module provides a separate operating environment for a set of network services. Each network device includes a control unit that receives configuration information that specifies individual weight values for each of the modules and a threshold value for the network device. The control unit detects failures of the modules and transfers primary responsibility for performing the network service to a second network device when the threshold value is exceeded by a weighted sum of the weight values for the failed modules.
摘要:
A method and device for performing and processing user-defined clipping in object space to reduce the number of computations needed for the clipping operation. The method and device also combine the modelview transformation of the vertex coordinates with projection transform. The user-defined clipping in object space provides a higher performance and less power consumption by avoiding generation of eye coordinates if there is no lighting. The device includes a driver for the user-defined clipping in the object space to perform dual mode user-defined clipping in object space when a lighting function is disabled and in eye space when the lighting function is enabled.