公开(公告)号：US4346988A

公开(公告)日：1982-08-31

申请号：US091777

申请日：1979-11-06

申请人： Hiroyuki Kimura ,  Shuichi Tamura ,  Hideo Yokota

发明人： Hiroyuki Kimura ,  Shuichi Tamura ,  Hideo Yokota

IPC分类号： G01C3/06 ,  G01C3/00 ,  G01S17/46 ,  G02B7/32 ,  G01C5/00 ,  H01L9/00

CPC分类号： G01S17/48

摘要： A distance measuring device having a light projector and a light receptor, at least one of which is caused to move so that when the intersection of their optical paths is disposed at an object, its coincidence is detected by the signal generated in the light receptor for measuring the distance from the device to the object based on the triangulation. In order to obtain a clear peak signal, according to the invention, for the light source, use is made of a light energy distribution characteristic which is higher at the marginal zone than at the central zone.

摘要翻译： 一种具有光投射器和光接收器的距离测量装置，其中至少一个被移动，使得当它们的光路的交点设置在物体上时，其重合通过在光接收器中产生的信号来检测， 基于三角测量来测量从设备到物体的距离。 为了获得清晰的峰值信号，根据本发明，对于光源，使用在边缘区域比在中心区域更高的光能分布特性。

公开(公告)号：US4238770A

公开(公告)日：1980-12-09

申请号：US79252

申请日：1979-09-27

申请人： Masaharu Kobayashi ,  Takao Arai ,  Takashi Hoshino ,  Hiroyuki Kimura ,  Keizo Nishimura

发明人： Masaharu Kobayashi ,  Takao Arai ,  Takashi Hoshino ,  Hiroyuki Kimura ,  Keizo Nishimura

IPC分类号： G11B20/10 ,  H04N5/10 ,  H04N5/932

CPC分类号： H04N5/932 ,  H04N5/10

摘要： There is disclosed a vertical synchronizing signal detector circuit for use with a PCM recording/reproducing system which records and reproduces audio signals with pulse code modulation by the use of a home VTR system or a part thereof. The vertical synchronizing signal detector circuit comprises an input terminal for receiving a composite synchronizing signal including a horizontal synchronizing signal and a vertical synchronizing signal, an output terminal for providing a vertical synchronizing pulse synchronized with the vertical synchronizing signal, a clock pulse generator circuit connected to the input terminal and adapted to generate a clock pulse having half the period of the horizontal synchronizing signal and a phase lag therefrom of one-fourth the period thereof, a vertical synchronizing signal extractor circuit connected to the input terminal and the clock pulse generator circuit and adapted to compare the vertical synchronizing signal with a reference waveform pattern for the vertical synchronizing signal so as to generate a vertical synchronizing signal output synchronized with the vertical synchronizing signal only when the comparison results in a complete coincidence, and a vertical synchronizing signal compensator circuit connected to the vertical synchronizing signal extractor circuit and the clock pulse generator circuit and responsive to the vertical synchronizing signal output to provide this output at the output terminal and simultaneously store the same temporarily, the vertical synchronizing signal compensator circuit being also adapted to provide the stored vertical synchronizing signal output at the output terminal when the vertical synchronizing signal output is not received, whereby the vertical synchronizing pulse is produced at correct timing even if the vertical synchronizing signal is absent in the composite synchronizing signal because of a dropout or the like.

摘要翻译： 公开了一种与PCM记录/再现系统一起使用的垂直同步信号检测器电路，其通过使用家用VTR系统或其一部分来记录和再现具有脉冲编码调制的音频信号。 垂直同步信号检测电路包括：输入端子，用于接收包括水平同步信号和垂直同步信号的复合同步信号;输出端，用于提供与垂直同步信号同步的垂直同步脉冲;时钟脉冲发生器电路，连接到 所述输入端子适于产生具有所述水平同步信号的一半周期的时钟脉冲及其四分之一周期的相位滞后;垂直同步信号提取器电路，连接到所述输入端子和所述时钟脉冲发生器电路;以及 适于将垂直同步信号与用于垂直同步信号的参考波形图案进行比较，以便仅当比较导致完全符合时产生与垂直同步信号同步的垂直同步信号，并且垂直同步信号 l补偿电路连接到垂直同步信号提取器电路和时钟脉冲发生器电路，并且响应于垂直同步信号输出以在输出端提供该输出并同时暂时存储，垂直同步信号补偿器电路还适于 当没有接收到垂直同步信号输出时，在输出端提供所存储的垂直同步信号，由此，即使在复合同步信号中缺少垂直同步信号，因此在正确定时产生垂直同步脉冲， 喜欢。

公开(公告)号：US4198602A

公开(公告)日：1980-04-15

申请号：US934717

申请日：1978-08-21

申请人： Hideo Nishijima ,  Isao Fukushima ,  Hiroyuki Kimura

发明人： Hideo Nishijima ,  Isao Fukushima ,  Hiroyuki Kimura

IPC分类号： H03G11/00 ,  H03G11/04 ,  H04B1/10

CPC分类号： H03G11/04 ,  H03G11/00 ,  H04B1/1027

摘要： A limiter circuit comprises a low-pass filter which passes only a modulation signal out of the modulation signal having pulsive noises superimposed thereon and circuit means for supplying the modulation signal extracted by the filter to current source circuits for a limiter differential amplifier to control the current source circuit for the limiter differential amplifier in accordance with a waveform of the input modulation signal applied thereto.

摘要翻译： 限幅器电路包括低通滤波器，其仅通过叠加有脉动噪声的调制信号通过调制信号;电路装置，用于将由滤波器提取的调制信号提供给限幅器差分放大器的电流源电路，以控制电流 根据施加到其的输入调制信号的波形，限幅差分放大器的源极电路。

公开(公告)号：US09278146B2

公开(公告)日：2016-03-08

申请号：US13269345

申请日：2011-10-07

申请人： Hideo Saji ,  Nobuya Inagaki ,  Hiroyuki Kimura ,  Kentaro Toyoda ,  Konomu Hirao ,  Hirokazu Matsuda

发明人： Hideo Saji ,  Nobuya Inagaki ,  Hiroyuki Kimura ,  Kentaro Toyoda ,  Konomu Hirao ,  Hirokazu Matsuda

IPC分类号： A61K51/00 ,  A61M36/14 ,  A61K51/08 ,  C07K14/575

CPC分类号： A61K51/08 ,  A61K51/088 ,  C07K14/57563

摘要： A new peptide derivative is provided. The peptide derivative is represented by the following general formula (I), where polypeptide ExP is polypeptide that contains completely or partially the amino acid sequence of exendin-4, and a -L-Z group represents a group represented by the following formula (II) that is bonded to an amino acid side chain of or the α-amino group at the N-terminus of the polypeptide ExP,

摘要翻译： 提供了一种新的肽衍生物。 肽衍生物由以下通式（I）表示，其中多肽ExP是完全或部分含有毒蜥外泌肽-4的氨基酸序列的多肽，-LZ基团表示由下式（II）表示的基团， 与多肽ExP的N末端的氨基酸侧链或α-氨基键合，

公开(公告)号：US09238083B2

公开(公告)日：2016-01-19

申请号：US12893896

申请日：2010-09-29

申请人： Hideo Saji ,  Nobuya Inagaki ,  Kentaro Toyoda ,  Hiroyuki Kimura ,  Konomu Hirao ,  Kenji Nagakawa ,  Hirokazu Matsuda

发明人： Hideo Saji ,  Nobuya Inagaki ,  Kentaro Toyoda ,  Hiroyuki Kimura ,  Konomu Hirao ,  Kenji Nagakawa ,  Hirokazu Matsuda

IPC分类号： A61K51/08 ,  C07K14/00

CPC分类号： A61K51/08

摘要： A molecular probe for imaging of pancreatic islets is provided. The molecular probe includes a polypeptide represented by the following formula (1), or a polypeptide that has a homology with the foregoing polypeptide. (SEQ ID NO. 1) Z-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPSX-NH2 (1) Wherein “X” represents a lysine residue, an amino group of a side chain of the lysine residue being labeled with a group represented by the following chemical formula (I), wherein A represents an aromatic hydrocarbon group or an aromatic heterocyclic group; R1 represents a substituent that contains 11C, 13N, 15O, 18F, 64Cu, 67Ga, 68Ga, 75Br, 76Br, 77Br, 99mTc, 111In, 123I, 124I, 125I, or 131I; R2 represents either a hydrogen atom, or a substituent different from that represented by R1; and R3 represents any one of a bond, an alkylene group having 1 to 6 carbon atoms, and an oxyalkylene group having 1 to 6 carbon atoms.

摘要翻译： 提供了用于胰岛成像的分子探针。 分子探针包括由下式（1）表示的多肽，或与前述多肽具有同源性的多肽。 （SEQ ID NO.1）Z-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPSX-NH2（1）其中，“X”表示赖氨酸残基，赖氨酸残基的侧链的氨基用下述化学式（I）表示的基团标记， 其中A表示芳族烃基或芳族杂环基; R1表示含有11C，13N，150C，18F，64Cu，67Ga，68Ga，75Br，76Br，77Br，99mTc，111In，123I，124I，125I或131I的取代基; R2表示氢原子或与R1表示的取代基不同的取代基; R3表示碳原子数1〜6的亚烷基，碳原子数1〜6的氧亚烷基。

公开(公告)号：US09044520B2

公开(公告)日：2015-06-02

申请号：US13434722

申请日：2012-03-29

申请人： Hideo Saji ,  Hiroyuki Kimura ,  Masahiro Ono ,  Ikuya Seki

发明人： Hideo Saji ,  Hiroyuki Kimura ,  Masahiro Ono ,  Ikuya Seki

IPC分类号： A61K51/00 ,  A61M36/14 ,  A61K51/08

CPC分类号： A61K51/088 ,  G01N2800/042

摘要： Embodiments of the invention provide a compound accumulating in an inflammatory site, a diagnostic agent containing the compound in labeled state and its precursor compound for labeling. Such a compound accumulating in inflammatory site may be represented by the following formula (1): Z—Y-Leu-Phe-(X)n-DLys(-(DLys)m-HalB)-(DLys)k-NH2  (1) wherein in the formula (1), Z represents a protective group for an amino group; Y represents Met or Nle; X represents a spacer consisting of one or more of amino acid and/or synthetic organic compounds; n represents 1 or 0; m represents 1 or 0; k represents 1 or 0; and HalB represents a substituted benzoic acid having a radioactive halogen in an aromatic ring.

摘要翻译： 本发明的实施方案提供了一种在炎症部位中积聚的化合物，含有标记状态的化合物的诊断剂及其用于标记的前体化合物。 Z-Y-Leu-Phe-（X）n-DLys（ - （DLys）m-HalB） - （DLys）k-NH 2（1）的化合物可以由下述式（1）表示： ）其中在式（1）中，Z表示氨基的保护基; Y表示Met或Nle; X表示由一种或多种氨基酸和/或合成有机化合物组成的间隔物; n表示1或0; m表示1或0; k表示1或0; HalB表示在芳香环中具有放射性卤素的取代苯甲酸。

公开(公告)号：US08980220B2

公开(公告)日：2015-03-17

申请号：US12964486

申请日：2010-12-09

申请人： Hideo Saji ,  Nobuya Inagaki ,  Kentaro Toyoda ,  Hiroyuki Kimura ,  Konomu Hirao ,  Kenji Nagakawa ,  Hirokazu Matsuda

发明人： Hideo Saji ,  Nobuya Inagaki ,  Kentaro Toyoda ,  Hiroyuki Kimura ,  Konomu Hirao ,  Kenji Nagakawa ,  Hirokazu Matsuda

IPC分类号： C07K14/605 ,  G01N33/74 ,  A61K51/08

CPC分类号： G01N33/74 ,  A61K51/088 ,  C07K14/605

摘要： A molecular probe for use in imaging of pancreatic islets is provided. The molecular probe comprises a polypeptide represented by the following formula (1), (2), or (3), or a polypeptide having homology with the foregoing polypeptide, (SEQ ID NO. 1) Z-HGEGTFTSDLSXQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2 (1) (SEQ ID NO. 2) Z-HGEGTFTSDLSKQMEEEAVRLFIEWLXNGGPSSGAPPPS-NH2 (2) (SEQ ID NO. 3) B-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2 (3) where, in the formulae (1) and (2), “X” represents a lysine residue, an amino group of a side chain of the lysine residue being labeled with a radioactive nuclide, and “Z—” indicates that an α-amino group at an N-terminus is not modified, or is modified with a modifying group having no electric charge; in the formula (3), “B—” indicates that an α-amino group at an N-terminus is labeled with a radioactive nuclide; and in the formulae (1), (2), and (3), “—NH2” indicates that a carboxyl group at a C-terminus is amidated.

摘要翻译： 提供了一种用于胰岛成像的分子探针。 分子探针包含由下式（1），（2）或（3）表示的多肽，或与前述多肽具有同源性的多肽（SEQ ID NO.1）Z-HGEGTFTSDLSXQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2（1）（ SEQ ID NO.2）Z-HGEGTFTSDLSKQMEEEAVRLFIEWLXNGGPSSGAPPPS-NH2（2）（SEQ ID NO.3）B-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2（3）其中，在式（1）和（2）中，“X”表示赖氨酸残基， 赖氨酸残基的侧链的氨基被放射性核素标记，“Z-”表示N末端的α-氨基未被修饰，或者是用不具有电荷的修饰基团修饰 ; 在式（3）中，“B-”表示N末端的α-氨基用放射性核素标记; 在式（1），（2）和（3）中，“-NH 2”表示C末端的羧基被酰胺化。

公开(公告)号：US08451263B2

公开(公告)日：2013-05-28

申请号：US13012209

申请日：2011-01-24

申请人： Tetsuo Morita ,  Hiroyuki Kimura

发明人： Tetsuo Morita ,  Hiroyuki Kimura

IPC分类号： G06F3/038 ,  G09G5/00

CPC分类号： H03K19/018507 ,  G09G3/3655 ,  G09G3/3677 ,  G09G2300/0876 ,  G09G2310/0286

摘要： In one embodiment, a driving circuit includes first, second, third and fourth transistors each having first and second electrodes, and a control gate electrode. First and second input signals for producing alternating current voltage are inputted to the respective first electrodes of the first and second transistors. The first electrode of the third transistor and the second electrode of the fourth transistor are commonly connected with an output terminal. The second electrode of the third transistor and the first electrode of the fourth transistor are respectively connected with first and second voltage sources. The control gate electrodes of the third and fourth transistors are respectively connected with the second electrodes of the first and second transistors. The driving circuit further includes first and second potential holding devices to control the switching operation of the third and fourth transistors to output the first and second voltages.

摘要翻译： 在一个实施例中，驱动电路包括每个具有第一和第二电极的第一，第二，第三和第四晶体管以及控制栅电极。 用于产生交流电压的第一和第二输入信号被输入到第一和第二晶体管的各个第一电极。 第三晶体管的第一电极和第四晶体管的第二电极与输出端子共同连接。 第三晶体管的第二电极和第四晶体管的第一电极分别与第一和第二电压源连接。 第三和第四晶体管的控制栅电极分别与第一和第二晶体管的第二电极连接。 驱动电路还包括用于控制第三和第四晶体管的开关操作以输出第一和第二电压的第一和第二电位保持装置。

公开(公告)号：US08384945B2

公开(公告)日：2013-02-26

申请号：US12203810

申请日：2008-09-03

申请人： Atsushi Torisaki ,  Hironobu Kitabatake ,  Hiroyuki Kimura

发明人： Atsushi Torisaki ,  Hironobu Kitabatake ,  Hiroyuki Kimura

IPC分类号： G06K15/00 ,  G06F3/12

CPC分类号： G06T11/60 ,  G06F3/1205 ,  G06F3/1208 ,  G06F3/1242 ,  G06F3/1245 ,  G06F3/1285

摘要： A printing apparatus includes a determination unit configured to determine whether objects overlap one another by analyzing print data, and a printing unit configured, if it is determined by the determination unit that the objects overlap one another, to separately print an image obtained before the objects overlap one another and an image obtained after the objects overlap one another based on the print data, and if it is determined by the determination unit that the objects do not overlap one another, to print an image based on the print data.

摘要翻译： 打印装置包括：确定单元，被配置为通过分析打印数据来确定对象是否彼此重叠;以及打印单元，如果由所述确定单元确定所述对象彼此重叠，则分别打印在所述对象之前获得的图像 基于打印数据，在物体彼此重叠之后获得的图像彼此重叠，并且如果确定单元确定对象彼此不重叠，则基于打印数据来打印图像。

公开(公告)号：US08282454B2

公开(公告)日：2012-10-09

申请号：US12893861

申请日：2010-09-29

申请人： Shigeru Miyamoto ,  Hiroyuki Kimura ,  Shigeyuki Asuke

发明人： Shigeru Miyamoto ,  Hiroyuki Kimura ,  Shigeyuki Asuke

IPC分类号： A63F9/24 ,  A63F13/00 ,  G06F17/00 ,  G06F19/00

CPC分类号： A63F13/56 ,  A63F13/10 ,  A63F13/20 ,  A63F13/21 ,  A63F13/235 ,  A63F13/25 ,  A63F13/327 ,  A63F13/45 ,  A63F13/58 ,  A63F13/822 ,  A63F13/843 ,  A63F2300/65 ,  A63F2300/8088

摘要： Example systems and methods relate to a multi-player video game in which multiple players each supply inputs to a respective input device to control a corresponding game character in a scrolling-type game world displayed on a display screen. A first predetermined input supplied by one of the players to the respective input device protects the one player's game character from harm in the game world and the protected game character moves based on the scrolling/non-scrolling state of the game world in accordance with the movement of one or more unprotected characters. The protecting of the one player's game character is stopped in response to one or more protecting stopping conditions, whereby the game character is again controllable by the one player in response to inputs to the respective input device.

摘要翻译： 示例系统和方法涉及多玩家视频游戏，其中多个玩家各自向相应的输入设备提供输入以控制显示在显示屏幕上的滚动型游戏世界中的相应游戏角色。 由玩家之一提供给相应输入装置的第一预定输入保护一个玩家的游戏角色免受游戏世界的伤害，受保护的游戏角色根据游戏世界的滚动/非滚动状态移动 一个或多个无保护字符的移动。 响应于一个或多个保护停止条件停止一个玩家的游戏角色的保护，由此响应于对相应输入设备的输入，一个玩家再次控制游戏角色。