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    LIMITED EXPANSION HEART VALVE
    122.
    发明申请
    LIMITED EXPANSION HEART VALVE 审中-公开
    有限扩口心阀

    公开(公告)号：US20170071732A1

    公开(公告)日：2017-03-16

    申请号：US15260053

    申请日：2016-09-08

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Da-Yu Chang

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2220/0033 ,  A61F2220/0075

    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. Interlocking members or flexible loops are included to limit expansion of the valve to one or two valve sizes, for example, with a 2-mm gap between each valve size. The valve may include an internal structural band with overlapped free ends having structure for limiting expansion, or external loops of suture may be added to the fabric covering which limits expansion.

    Abstract translation: 公开了一种假体心脏瓣膜，其构造成替代原生心脏瓣膜并且具有构造成重新成形为膨胀形式以支撑可膨胀假体心脏瓣膜和/或支撑其中的可扩张假体心脏瓣膜的支撑框架及其使用方法。 包括联锁构件或柔性环，以将阀的膨胀限制为一个或两个阀的尺寸，例如每个阀尺寸之间的间隙为2mm。 阀可以包括具有重叠自由端的内部结构带，其具有用于限制膨胀的结构，或者缝合线的外部环可以被添加到限制膨胀的织物覆盖物中。

    Dynamic annuloplasty ring sizer
    123.
    发明授权
    Dynamic annuloplasty ring sizer 有权

    公开(公告)号：US09351833B2

    公开(公告)日：2016-05-31

    申请号：US14867992

    申请日：2015-09-28

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin

    IPC: A61B5/00 ,  A61F2/24 ,  A61B5/107 ,  A61B19/00

    CPC classification number: A61F2/2496 ,  A61B5/107 ,  A61B5/1076 ,  A61B5/6852 ,  A61B5/6869 ,  A61B90/06 ,  A61B2090/0807 ,  A61F2/2445 ,  A61F2/2472 ,  A61F2250/001 ,  A61F2250/0097

    Abstract: A dynamic, adjustable annuloplasty ring sizer can include an adjustable ring replica, which can be adjusted through a range of sizes corresponding to available prosthetic annuloplasty repair ring sizes. Actuation of an adjustment trigger on a handle portion of the ring sizer can displace tension wires that extend through a malleable shaft and through a plurality of articulating segments that form the ring replica. Displacement of the tension wires causes flexion of the joints between adjacent articulating segments, thereby reducing the overall size of the ring replica. Releasing the tension wires can allow an elastic extension wire to act on the ring replica, enlarging the ring replica to its maximum, at-rest size. In this manner, the appropriate size of annuloplasty ring prosthesis can be determined with a single device, without requiring a plurality of static ring sizers that require individual insertion and placement for the conventional trial-and-error sizing methods.

    Force-based heart valve sizer
    124.
    发明授权
    Force-based heart valve sizer 有权

    公开(公告)号：US09277996B2

    公开(公告)日：2016-03-08

    申请号：US14011602

    申请日：2013-08-27

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Da-Yu Chang

    IPC: A61F2/24 ,  A61B19/00 ,  A61B5/107

    CPC classification number: A61B5/1076 ,  A61B5/02028 ,  A61B5/6859 ,  A61B2090/064 ,  A61B2090/065 ,  A61B2090/066 ,  A61F2/243 ,  A61F2/2496

    Abstract: A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals.

    Dynamic annuloplasty ring sizer
    125.
    发明授权
    Dynamic annuloplasty ring sizer 有权
    动态瓣环成形术

    公开(公告)号：US09149360B2

    公开(公告)日：2015-10-06

    申请号：US14187084

    申请日：2014-02-21

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin

    IPC: A61F2/24 ,  A61B5/107 ,  A61B19/00

    CPC classification number: A61F2/2496 ,  A61B5/107 ,  A61B5/1076 ,  A61B5/6852 ,  A61B5/6869 ,  A61B90/06 ,  A61B2090/0807 ,  A61F2/2445 ,  A61F2/2472 ,  A61F2250/001 ,  A61F2250/0097

    Abstract: A dynamic, adjustable annuloplasty ring sizer can include an adjustable ring replica, which can be adjusted through a range of sizes corresponding to available prosthetic annuloplasty repair ring sizes. Actuation of an adjustment trigger on a handle portion of the ring sizer can displace tension wires that extend through a malleable shaft and through a plurality of articulating segments that form the ring replica. Displacement of the tension wires causes flexion of the joints between adjacent articulating segments, thereby reducing the overall size of the ring replica. Releasing the tension wires can allow an elastic extension wire to act on the ring replica, enlarging the ring replica to its maximum, at-rest size. In this manner, the appropriate size of annuloplasty ring prosthesis can be determined with a single device, without requiring a plurality of static ring sizers that require individual insertion and placement for the conventional trial-and-error sizing methods.

    Abstract translation: 动态，可调节瓣环成形术环形筛分器可以包括可调整的环形复制件，其可以通过对应于可用的假体瓣环成形术修复环尺寸的一系列尺寸进行调整。 在环形筛分机的手柄部分上的调节触发器的致动器可以移动延伸穿过可延展的轴并通过形成环形复制件的多个铰接段的张力线。 张力线的位移导致相邻铰接段之间的接头弯曲，从而减小环形复制体的总体尺寸。 释放张力线可以允许弹性延伸线作用在环形复制品上，将环形复制品放大到最大静止尺寸。 以这种方式，可以使用单个装置来确定瓣环成形术假体的适当尺寸，而不需要多个静态环形筛分器，其需要单独的插入和放置用于常规的试验和误差尺寸测量方法。

    Side-entry knotless suture anchoring clamps and deployment tools
    127.
    发明授权
    Side-entry knotless suture anchoring clamps and deployment tools 有权
    侧入式无缝缝合锚固夹具和部署工具

    公开(公告)号：US09078652B2

    公开(公告)日：2015-07-14

    申请号：US13920983

    申请日：2013-06-18

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  Donald E. Bobo, Jr.

    IPC: A61B17/04

    CPC classification number: A61B17/0487 ,  A61B17/0401 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0416 ,  A61B2017/0464 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2442

    Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.

    Abstract translation: 用于固定假体（例如心脏瓣膜或带有缝线和瓣环的瓣环成形术环）的缝合线锁定件提高了植入的容易性。 夹具具有相对的夹具半部，该半部由通向一侧的狭槽分开，并被诸如一个或多个C形夹弹簧的偏置构件包围。 缝合线横向穿过狭槽，狭槽由位于夹子半部之间的保持构件保持打开。 锁定夹具沿着缝合线滑动到适当位置，调节缝合线的张力，并且移除保持构件以允许偏置构件将缝合线夹在夹具半部之间。 用于传送和展开锁定夹具的输送工具在堆叠中的输送管内包含多个夹具，并且为了安全而将其粘合在一起并具有公共保持构件。 该工具在一侧具有用于进入缝合线的纵向通道。

    SELF-CINCHING SURGICAL CLIPS AND DELIVERY SYSTEM
    128.
    发明申请
    SELF-CINCHING SURGICAL CLIPS AND DELIVERY SYSTEM 有权
    自我修复手术和输送系统

    公开(公告)号：US20150173759A1

    公开(公告)日：2015-06-25

    申请号：US14637177

    申请日：2015-03-03

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  James A. Davidson ,  Ralph Schneider

    IPC: A61B17/10

    CPC classification number: A61B17/10 ,  A61B17/064 ,  A61B17/068 ,  A61B17/105 ,  A61B2017/0645 ,  A61B2017/0649

    Abstract: A device and method for deploying self-cinching surgical clips. The device accesses at least two layers of tissue or material from only one side of the tissue or material and punctures through the two layers of tissue or material. The various configurations of clips disclosed herein are made of a superelastic material such as Nitinol, and have a constrained and a relaxed state, and no sharp edges or tips so as to reduce tissue irritation following deployment. The clip is disposed within the housing of the delivery device and held in a constrained state by a tube assembly until deployment wherein the clip assumes its relaxed state, where the ends of the clip are brought into close approximation, thereby securing the layers of tissue or material together.

    Abstract translation: 一种用于部署自闭式手术夹的装置和方法。 该装置仅从组织或材料的一侧接近至少两层组织或材料，并穿刺穿过两层组织或材料。 本文公开的夹子的各种构造由超弹性材料（例如镍钛诺）制成，并且具有约束和松弛状态，并且没有锋利的边缘或尖端，以便在部署之后减少组织刺激。 夹子设置在输送装置的壳体内，并通过管组件保持在约束状态，直到展开为止，其中夹子呈现其松弛状态，其中夹子的端部被近似近似，从而固定组织层或 材料在一起

    Self-cinching surgical clips and delivery system
    129.
    发明授权
    Self-cinching surgical clips and delivery system 有权
    自体手术夹子和输送系统

    公开(公告)号：US08968336B2

    公开(公告)日：2015-03-03

    申请号：US13693952

    申请日：2012-12-04

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  James A. Davidson ,  Ralph Schneider

    IPC: A61B17/10 ,  A61B17/068 ,  A61B17/064

    CPC classification number: A61B17/10 ,  A61B17/064 ,  A61B17/068 ,  A61B17/105 ,  A61B2017/0645 ,  A61B2017/0649

    Abstract: A device and method for deploying self-cinching surgical clips. The device accesses at least two layers of tissue or material from only one side of the tissue or material and punctures through the two layers of tissue or material. The various configurations of clips disclosed herein are made of a superelastic material such as Nitinol, and have a constrained and a relaxed state, and no sharp edges or tips so as to reduce tissue irritation following deployment. The clip is disposed within the housing of the delivery device and held in a constrained state by a tube assembly until deployment wherein the clip assumes its relaxed state, where the ends of the clip are brought into close approximation, thereby securing the layers of tissue or material together.

    Abstract translation: 一种用于部署自闭式手术夹的装置和方法。 该装置仅从组织或材料的一侧接近至少两层组织或材料，并穿刺穿过两层组织或材料。 本文公开的夹子的各种构造由超弹性材料（例如镍钛诺）制成，并且具有约束和松弛状态，并且没有锋利的边缘或尖端，以便在部署之后减少组织刺激。 夹子设置在输送装置的壳体内，并通过管组件保持在约束状态，直到展开为止，其中夹子呈现其松弛状态，其中夹子的端部被近似逼近，由此固定组织层或 材料在一起

    FORCE-BASED HEART VALVE SIZER
    130.
    发明申请
    FORCE-BASED HEART VALVE SIZER 有权

    公开(公告)号：US20130345801A1

    公开(公告)日：2013-12-26

    申请号：US14011602

    申请日：2013-08-27

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Da-Yu Chang

    IPC: A61F2/24

    CPC classification number: A61B5/1076 ,  A61B5/02028 ,  A61B5/6859 ,  A61B2090/064 ,  A61B2090/065 ,  A61B2090/066 ,  A61F2/243 ,  A61F2/2496

    Abstract: A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals.

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