Quadrupole ion trap device and methods of operating a quadrupole ion trap device
    121.
    发明申请
    Quadrupole ion trap device and methods of operating a quadrupole ion trap device 有权
    四极离子阱装置及操作四极离子阱装置的方法

    公开(公告)号:US20050061966A1

    公开(公告)日:2005-03-24

    申请号:US10494493

    申请日:2002-10-24

    CPC classification number: H01J49/424 H01J49/06

    Abstract: A quadrupole ion trap device has a field adjusting electrode located outside the trapping region adjacent the aperture in the entrance end cap electrode, and optionally adjacent the aperture in the exit end cap electrode. The field adjusting electrode(s) controls field distortion in the vicinity of the apertures. By appropriately setting the voltages on the field adjusting electrodes the efficiency and resolution of operational processes such as ion introduction, precursor ion isolation and mass scanning can be improved.

    Abstract translation: 四极离子阱装置具有位于与入口端盖电极中的孔附近的捕获区域外部的场调节电极,并且可选地邻近出口端盖电极中的孔。 场调节电极控制孔附近的场失真。 通过适当地设定场调节电极上的电压,可以提高离子引入,前体离子隔离和质量扫描等操作过程的效率和分辨率。

    Dynamic circuits having improved noise tolerance and method for designing same
    122.
    发明申请
    Dynamic circuits having improved noise tolerance and method for designing same 有权
    具有改进的噪声容限的动态电路及其设计方法

    公开(公告)号:US20050007153A1

    公开(公告)日:2005-01-13

    申请号:US10847018

    申请日:2004-05-17

    CPC classification number: H03K19/0963

    Abstract: A number of different dynamic circuits having improved noise tolerance and a method for designing same are provided. The circuits include a power supply node and a precharge node. Keeper circuitry is connected to the nodes and has a current-voltage characteristic that exhibits a negative differential resistance property to improve noise tolerance of the circuits.

    Abstract translation: 提供了许多具有改进的噪声容限的不同动态电路及其设计方法。 电路包括电源节点和预充电节点。 Keeper电路连接到节点,并具有呈现负差分电阻特性的电流 - 电压特性,以改善电路的噪声容限。

    Stabilized liposomes
    123.
    发明授权
    Stabilized liposomes 失效
    稳定的脂质体

    公开(公告)号:US5962015A

    公开(公告)日:1999-10-05

    申请号:US850052

    申请日:1997-05-02

    CPC classification number: A61K9/1273

    Abstract: Lecithin-type liposomes are stabilized with quaternized alkyated polymers, such as steardimonium hydroxyethylcellulose, to provide excellent stability for cosmetic and pharmaceutical formulations. Temperature, storage, solvent, and acidity stability are described. The stabilized liposomes can serve as vectors for alpha-hydroxy acids and showed no aggregation even after 4 months of storage at pH 2.

    Abstract translation: 卵磷脂型脂质体通过季铵化的烷基化聚合物例如羟乙基纤维素钠稳定化,为化妆品和药物制剂提供优异的稳定性。 描述了温度,储存,溶剂和酸度稳定性。 稳定的脂质体可以用作α-羟基酸的载体,即使在pH 2下储存4个月后也不显示聚集。

    Derivatives of metalloporphyrins and application thereof for therapeutic
purposes and in preparing hybrid molecules
    124.
    发明授权
    Derivatives of metalloporphyrins and application thereof for therapeutic purposes and in preparing hybrid molecules 失效
    金属酞菁的衍生物及其应用于治疗用途和制备混合分子

    公开(公告)号:US5236914A

    公开(公告)日:1993-08-17

    申请号:US613638

    申请日:1990-11-28

    Abstract: Metalloporphyrin derivatives of the formula ##STR1## in which A and B each represents: ##STR2## and Z.sup.+ represents N.sup.+ --R.sub.1 or C--N.sup.+ R.sub.1 R.sub.2 R.sub.3, R.sub.1 being C.sub.1 -C.sub.10 linear or branched aliphatic, andR.sub.2 and R.sub.3 each being hydrogen or C.sub.1 -C.sub.10 linear or branched aliphatic,R represents NH.sub.2, OH, COOH or --N(R.sub.1).sub.3 group or a halogen,n is 0 or an integer from 1 to 10, the corresponding alkylene group being either linear or branched,M represents Fe or Mn, andX represents the anion of a pharmaceutically acceptable carboxylic acid, m being an integer from 1 to 5, andY represents a bond or a --O--, --CO-- or --CONH-- radical.The compounds have antitumoral and antiviral utility.

    Abstract translation: PCT No.PCT / FR89 / 00273 Sec。 371日期1990年11月28日 102(e)日期1990年11月28日PCT Filed Jun.2,1989 PCT Pub。 第WO89 / 12049号公报 日期为1989年12月14日。其中A和B各自表示的式“IMAGE”I的金属卟啉衍生物:IMA和Z +表示N + -R1或C-N + R1R2R3,R1为C1-C10直链或支链脂族, 和R 2和R 3各自为氢或C 1 -C 10直链或支链脂族,R表示NH 2,OH,COOH或-N(R 1)3基或卤素,n为0或1至10的整数,相应的亚烷基 是直链或支链的,M表示Fe或Mn,X表示药学上可接受的羧酸的阴离子,m为1至5的整数,Y表示键或-O - , - CO-或-CONH - 激进 该化合物具有抗肿瘤和抗病毒效用。

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