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公开(公告)号：US07033786B2
公开(公告)日：2006-04-25
申请号：US10015715
申请日：2001-12-12
Applicant: Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood
Inventor： Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Victoria Smith , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood
CPC classification number: C07K14/47
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US06969758B2
公开(公告)日：2005-11-29
申请号：US10033435
申请日：2001-12-27
Applicant: Napoleone Ferrara , Wei-Qiang Gao , Audrey Goddard , Austin L. Gurney , Colin K. Watanabe , William I. Wood
Inventor： Napoleone Ferrara , Wei-Qiang Gao , Audrey Goddard , Austin L. Gurney , Colin K. Watanabe , William I. Wood
IPC: A61K38/00 , C07H21/04 , C07K1/00 , C07K14/435 , C07K14/47 , C07K16/00 , C07K16/40 , C12N1/18 , C12N1/21 , C12N5/06 , C12N9/00 , C12N9/64 , C12N15/74 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/53
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US06936697B2
公开(公告)日：2005-08-30
申请号：US10006768
申请日：2001-12-06
Applicant: Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Colin K. Watanabe , William I. Wood
Inventor： Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Colin K. Watanabe , William I. Wood
IPC: C07K14/705 , C07K16/28 , C07K14/00 , C12N15/62
CPC classification number: C07K14/705 , C07K2319/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US08063186B2
公开(公告)日：2011-11-22
申请号：US10194359
申请日：2002-07-12
Applicant: Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Victoria Smith , Colin K. Watanabe , William I. Wood
Inventor： Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Victoria Smith , Colin K. Watanabe , William I. Wood
IPC: C07K16/18 , A61K39/395
CPC classification number: C07K14/47 , A01K2217/075 , A01K2227/105 , A61K38/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/28 , C07K2319/30 , C12Q1/6816 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5082 , G01N33/5308 , G01N33/574 , G01N33/57419 , G01N33/57423 , G01N33/57434 , G01N33/57484 , G01N33/57488 , G01N33/57492 , G01N2500/00 , C12Q2563/131 , C12Q2527/137
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07728108B2
公开(公告)日：2010-06-01
申请号：US11929465
申请日：2007-10-30
Applicant: Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
Inventor： Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
CPC classification number: C07K14/705 , C07K16/28 , C07K2317/24 , C07K2319/30 , C07K2319/40
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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Patent Agency Ranking
公开(公告)号：US20100028343A1
公开(公告)日：2010-02-04
申请号：US12549497
申请日：2009-08-28
Applicant: Jian Chen , Ellen Filvaroff , Sherman Fong , Dorothy French , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Sarah G. Hymowitz , Hanzhong Li , James Pan , Melissa A. Starovasnik , Daniel Tumas , Menno Van Lookeren , Richard Vandlen , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Daniel G. Yansura
Inventor： Jian Chen , Ellen Filvaroff , Sherman Fong , Dorothy French , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Sarah G. Hymowitz , Hanzhong Li , James Pan , Melissa A. Starovasnik , Daniel Tumas , Menno Van Lookeren , Richard Vandlen , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Daniel G. Yansura
IPC: A61K39/395 , A61P19/02
CPC classification number: C07K16/244 , A61K38/00 , C07H21/04 , C07K14/54 , C07K14/7155 , C07K2317/21 , C07K2317/24 , C07K2317/35 , C07K2317/54 , C07K2317/55 , C07K2317/62 , G01N33/505 , G01N33/564 , G01N33/574 , G01N33/57407 , G01N33/57423 , G01N33/57438 , G01N33/57492 , G01N2333/54 , G01N2333/7155
Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
Abstract translation: 本发明涉及与IL-17，IL-17受体和编码那些多肽的核酸分子具有序列同一性的新型多肽。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。 本文还提供了治疗退行性软骨疾病和其它炎性疾病的方法。
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公开(公告)号：US20090318672A1
公开(公告)日：2009-12-24
申请号：US12319421
申请日：2009-01-06
Applicant: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
Inventor： Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C07K16/18
CPC classification number: C07K14/47 , A01K2217/075 , A01K2227/105 , A61K38/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/28 , C07K2319/30 , C12Q1/6816 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5082 , G01N33/5308 , G01N33/574 , G01N33/57419 , G01N33/57423 , G01N33/57434 , G01N33/57484 , G01N33/57488 , G01N33/57492 , G01N2500/00 , C12Q2563/131 , C12Q2527/137
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07534856B2
公开(公告)日：2009-05-19
申请号：US10195889
申请日：2002-07-15
Applicant: Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
Inventor： Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
CPC classification number: C07K14/47 , A01K2217/075 , A01K2227/105 , A61K38/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/28 , C07K2319/30 , C12Q1/6816 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5082 , G01N33/5308 , G01N33/574 , G01N33/57419 , G01N33/57423 , G01N33/57434 , G01N33/57484 , G01N33/57488 , G01N33/57492 , G01N2500/00 , C12Q2563/131 , C12Q2527/137
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Abstract translation: 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。
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公开(公告)号：US07507404B2
公开(公告)日：2009-03-24
申请号：US10063570
申请日：2002-05-02
Applicant: Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
Inventor： Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
IPC: A61K39/395 , C07K16/00 , C07K16/18 , C07K16/30
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4703 , C07K14/52 , C07K14/54 , C07K14/705 , C07K14/70578 , C07K16/18 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N2799/026 , C12N2799/027
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号：US20080286821A1
公开(公告)日：2008-11-20
申请号：US11263278
申请日：2005-10-31
Applicant: Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
Inventor： Dan L. Eaton , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Colin K. Watanabe , William I. Wood
IPC: C12Q1/02 , C12N15/11 , C12N15/00 , C12N5/06 , C12N1/20 , C12N1/14 , C12P21/04 , C07K14/00 , C07K16/18
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4703 , C07K14/52 , C07K14/54 , C07K14/705 , C07K14/70578 , C07K16/18 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N2799/026 , C12N2799/027
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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